- 1 Tablets Supraks - drug description
- 2 Forms of release, composition
- 3 Indications for use
- 4 Instructions for use
- 5 Contraindications
- 6 adverse reactions
- 7 Analogs
- 8 Application Reviews
The instructions for use of the drug Supraks indicated that this is the first third-generation cephalosporin antibiotic, intended for oral administration. The drug is used to treat bacterial infections in adults and children in various fields of medicine - therapy, urology, dermatology, gynecology, otolaryngology.
Supraks tablets - a description of the drug
Suprax is a semi-synthetic antibacterial drug from the group of third-generation cephalosporins. Active ingredient - cefixime has a wide range of bactericidal action. The antibacterial effect is achieved due to the destruction of a special substance responsible for the construction of bacterial cell walls, which leads to the death of microorganisms.
The advantage of the drug is immunity to beta-lactamase, which bacteria have learned to produce to protect against antibiotics. Thanks to this property, Supraks does not lose its effectiveness, since most pathogenic microorganisms are not capable of producing resistance to the active substance of the preparation. The cephalosporin antibiotic exhibits bactericidal activity against the following microorganisms:
- intestinal and hemophilic coli;
- gonokokki and so forth.
At the same time, the drug is ineffective against most strains of Staphylococcus aureus, Pus bacillus, Listeria, and enterobacteria.
The active substance of the drug is not presented in pure form, but in the form of salt (cefixime trihydrate), which protects it from the aggressive effects of hydrochloric acid in the stomach. As a result, the antibiotic is released only in the intestine, from which it enters the bloodstream. Bioavailability of the drug is about 50%, food intake does not affect this indicator.
An antibacterial agent is eliminated from the body during the day, while up to 50% is excreted in the urine, about 10% in bile. A longer half-life allows you to take the drug only 1 time per day, which is a significant advantage compared with other antibiotics.
Forms of release, composition
Antibacterial agent is available in three dosage forms:
- Suprax tablets dispersible - oblong orange tablets with a risk on both sides and a pleasant strawberry flavor, contain 400 mg of cefixime. The composition of Supraksa complements the set of auxiliary components. The drug is presented in the pharmacy network called Supraks Solyutab. In a carton pack there is a blister in which 1, 5 or 7 dispersible tablets are inserted.
- Suprax 400 mg - oblong capsules with a white body and a purple lid, inside which are small yellowish granules. Each capsule contains 400mg cefixime + auxiliary components. This form of the drug is intended for adult patients. Capsules of 6 pcs. packaged in blisters and placed in cardboard packaging.
- Suspension Supraks - children's form of release in the form of small granules intended for the preparation of suspensions. After their dissolution in water, a suspension of white or cream-colored with a sweetish taste and the smell of strawberries is formed. In 5 ml of this suspension is 100 mg cefixime. The granules are placed in dark glass bottles, a dosing syringe or a measuring spoon are put into the package with the drug. With their help, it is convenient to measure the necessary dose of medication.
Indications for use
Suprax and Suprax Solutab are prescribed for the treatment of infectious-inflammatory diseases caused by microorganisms sensitive to the active substance of the drug. These include:
- infectious processes (acute and chronic) affecting the respiratory tract - bronchitis, sinusitis, pharyngitis, tonsillitis;
- infectious lesions of the urinary tract (cystitis, urethritis, cystourethritis, cystitis, pyelonephritis);
- inflammation of the middle ear (otitis media);
- gonorrhea without complications.
Instructions for use
The dosage and regimen of the cephalosporin antibiotic should be selected by the doctor taking into account the age and weight of the patient, the severity of the disease, the presence of possible contraindications.
According to the instructions, the standard dose of Supraks capsules for adults and children over 12 years old is 400 mg (1 tablet) per day. In addition to the antibiotic, there is an additional weight limit, so if the young growth over 12 years of age does not reach 50 kg, it is not recommended to prescribe the medicine.
The capsule should be swallowed whole, without chewing and emptying the contents. The drug must be washed down with a sufficient amount of water (at least 100 ml). The capsule can be swallowed at any convenient time, regardless of the meal. On average, the course of treatment takes from 7 to 10 days. When treating gonorrhea, a single dose of 1 capsule (400 mg) is sufficient.
Tablets are recommended to be swallowed whole, washed down with a large volume of liquid, or dissolved in a small volume of cool boiled water and immediately drunk. For adult patients and adolescents over 12 years old, weighing more than 50 kg, the daily dosage is the same as for capsules. That is, one pill can be taken at any convenient time of the day, regardless of the meal.
Suprax for children and adolescents weighing from 25 to 50 kg is taken in a dosage reduced by half - 1/2 tablet (200mg) once a day.
The duration of the course of therapy depends on the type of disease. In case of mild urinary tract infections in women, the duration of the medication is from 3 to 10 days, while treating pyelonephritis or cystitis, the course of therapy can be extended to 14 days. In men, the treatment of such pathologies takes from 7 to 14 days. Treatment of uncomplicated gonorrhea takes only one day, recovery occurs after a single pill (400 mg).
How many days does Suprax take for a child during the treatment of ENT diseases? It all depends on the severity of the symptoms and the general condition of the patient. On average, in the treatment of respiratory tract infections, children and adults take an antibiotic for 7-14 days. In this case, both adults and children need to continue taking pills for another 1-2 days after the body temperature returns to normal, and all symptoms of the infection disappear.
The drug in the form of a suspension is intended for the treatment of children aged 6 months to 12 years. The dosage of the drug is calculated individually by the doctor, taking into account the body weight and the age of the small patient. The calculation is made from the ratio of 8mg / kg of weight. The calculated dose is given to the child once a day or divided into two doses.
How much water should be added to the Suprax suspension and how to properly dilute it? After opening the package, the bottle of granules should be shaken, open the lid, measure 40 ml of cool boiled water with a syringe and gradually add it to the preparation in 2 stages. In the process of introducing the liquid, the vial should be shaken to achieve a homogeneous state of the suspension. For complete dissolution of the granules, 5 minutes is enough, after which the ready suspension can be given to the child.
For babies from 6 to 12 months, the daily dose of the drug is 2.5-4 ml. It can be given at one time or divided into two doses (in the morning and in the evening).
For children from 2 to 4 years a single dose of the suspension is 5 ml (1 scoop). After 5 years, the child can be given from 6 to 10 ml of suspension per day. How many days does the baby take Suprax in suspension? On average, the duration of treatment for streptococcal infections is at least 10 days. In angina, the treatment takes from 7 to 14 days.
Modern antibiotic has few contraindications. It is not prescribed for hypersensitivity to antibiotics of the penicillin and cephalosporin, in violation of renal functions, renal failure, pseudomembranous colitis (including history). With extreme caution and under the supervision of a physician Supraks used in elderly patients and young children.
Suprax during pregnancy can be prescribed only in the case when the intended benefit to the mother exceeds the possible risks to the developing fetus. In practice, gynecologists quite often prescribe a cephalosporin antibiotic to pregnant women, since this is the safest option compared with other antibacterial agents.
If there is a need to use the drug during lactation, the baby should be temporarily transferred to artificial mixtures. You can return to breastfeeding a day after the end of the antibiotic.
Suprax is well tolerated by patients and rarely causes adverse reactions. The most common of these are malaise associated with the digestive system. During treatment, nausea, dry mouth, lack of appetite, vomiting, abdominal pain, flatulence, constipation or diarrhea may appear.
Symptoms of glossitis, stomatitis, enterocolitis, and dysbacteriosis are possible. In the process of treatment, there is a violation of blood parameters, headaches, dizziness, tinnitus, shortness of breath. Hypovitaminosis sometimes develops, renal function deteriorates, and in rare cases nephritis or acute renal failure occurs.
If you are hypersensitive, allergic reactions are observed (hyperemia, pruritus, urticaria, fever), in exceptional cases, dangerous conditions develop - angioedema, anaphylactic shock.
An overdose of the drug increases the severity of side effects. Washing the stomach and taking sorbents (activated carbon, Polysorb) will help to relieve the unpleasant symptoms.
Prolonged use of Supraksa can lead to dysbiosis, provoke the development of pseudomembranous colitis and severe diarrhea. Therefore, in the course of treatment all medical recommendations should be strictly followed and the drug should not be used for longer than the specified period.
It should be borne in mind that the use of diuretics simultaneously in Suprax, slows down its excretion by the kidneys, which can lead to an increase in the concentration of cefixime in the blood. Antacids slow down the absorption of Supraksa - the time interval between taking these medicines should be 2-4 hours.
Among the structural analogues of Supraksa we can name the following antibiotics:
- Ixim Lupine;
- Ceforal Solyutab;
Among other drugs with a similar therapeutic effect, but with another active ingredient, Sumamed, Amoxiclav, Lendatsin.
The price of Supraks depends on the form of the drug and the manufacturer. The average cost of antibiotics in pharmacies is:
- Supraks capsules 400mg (6 pieces) - from 680 rubles;
- Supraks Solyutab tablets (7 pieces) - from 800 to 1000 rubles;
- Suprax in granules (suspension) - from 550 to 700 rubles.
The overwhelming majority of reviews of Supraks are positive. Patients note the high efficacy of the antibiotic in the treatment of severe infectious diseases, ease of use (1 time per day) and the possibility of use in young children. The disadvantages of the drug include the high cost and the presence of side effects.
My son, aged 3, was prescribed Suprax suspension in the treatment of prolonged bronchitis. At first they offered to make injections of the antibiotic, but I refused. The son is very difficult to tolerate such manipulations.
But the sweetish suspension with a strawberry smell drank without objection. We really liked this drug. Firstly, it is necessary to take it only once a day, and secondly, the medicine very quickly eliminated all the symptoms of the disease.
Marina, St. Petersburg
Review number 2
Capsules Supraks took with cystitis 1 piece per day. It is very convenient, you can drink the medicine at any time, regardless of the meal. An antibiotic is expensive, but it justifies its price.
Quickly removes all unpleasant symptoms and provides recovery in just 5-7 days. Yes, and the side effects of the drug is not as much as other antibiotics.