Suprax solutab 400 mg tablets: instructions for use, price

The instructions for use of the drug Suprax indicate that this is the first cephalosporin antibiotic of the 3rd generation, intended for oral administration. The drug is used to treat bacterial infections in adults and children in various fields of medicine - therapy, urology, dermatology, gynecology, otolaryngology.

Suprax tablets - description of the drug

Suprax is a semi-synthetic antibacterial drug from the group of 3rd generation cephalosporins. The active ingredient, cefixime, has a broad spectrum of bactericidal action. The antibacterial effect is achieved by destroying a special substance responsible for building the cell walls of bacteria, which leads to the death of microorganisms.

The advantage of the drug is its immunity to beta-lactamases, which bacteria have learned to produce to protect against antibiotics. Due to this property, Suprax does not lose its effectiveness, since most pathogenic microorganisms are not able to develop resistance to the active substance of the drug. The cephalosporin antibiotic exhibits bactericidal activity against the following microorganisms:

• streptococci;
• salmonella;
• Proteus;
• Escherichia coli and Haemophilus influenzae;
• klebsiella;
• shigella;
• gonococci, etc.

At the same time, the drug is ineffective against most strains of staphylococcus, Pseudomonas aeruginosa, listeria, enterobacteria.

The active substance of the drug is not presented in pure form, but in the form of a salt (cefixime trihydrate), which protects it from the aggressive effects of hydrochloric acid in the stomach. As a result, the antibiotic is released only in the intestines, from where it enters the bloodstream. The bioavailability of the drug is about 50%, food intake does not affect this indicator.

The antibacterial agent is excreted from the body within a day, while up to 50% leaves with urine, about 10% with bile. A longer half-life allows you to take the drug only once a day, which is a significant advantage compared to other antibiotics.

Forms of release, composition

The antibacterial agent is available in three dosage forms:

• Suprax tablets dispersible - oblong orange tablets with a scored on both sides and a pleasant strawberry aroma, containing 400 mg of cefixime. The composition of Suprax complements the set of auxiliary components. The drug is presented in a pharmacy chain called Suprax Solutab. The cardboard box contains a blister containing 1, 5 or 7 dispersible tablets.
• Suprax 400 mg - capsules of an oblong shape with a white body and a purple lid, inside which there are small yellowish granules. Each capsule contains 400mg cefixime + auxiliary components. This form of the drug is intended for adult patients. 6 capsules packaged in blisters and placed in cardboard boxes.
• Suspension Suprax - children's form of release in the form of small granules intended for the preparation of a suspension. After dissolving them in water, a white or cream-colored suspension with a sweetish taste and strawberry smell is formed. 5 ml of such a suspension contains 100 mg of cefixime. The granules are placed in dark glass vials, a dosage syringe or a measuring spoon is placed in the package with the drug. With their help, it is convenient to measure the required dose of the medicine.

Indications for use

Suprax and Suprax Solutab are prescribed for the treatment of diseases of an infectious and inflammatory nature, provoked by microorganisms sensitive to the active substance of the drug. These include:

• infectious processes (acute and chronic) affecting the respiratory tract - bronchitis, sinusitis, pharyngitis, tonsillitis;
• infectious lesions of the urinary tract (cystitis, urethritis, cystourethritis, cystitis, pyelonephritis);
• otitis media (otitis media);
• shigellosis;
• gonorrhea without complications.

Instructions for use

The dosage and regimen for taking the cephalosporin antibiotic should be selected by the doctor, taking into account the age and weight of the patient, the severity of the disease, and the presence of possible contraindications.

Suprax capsules

According to the instructions, the standard dose of Suprax capsules for adults and children over 12 years old is 400 mg (1 tablet) per day. There is an additional weight restriction to the antibiotic intake, so if the undergrowth over 12 years old does not weigh 50 kg, it is not recommended to prescribe a medicine.

The capsule should be swallowed whole without chewing or spilling the contents. The drug must be taken with a sufficient amount of water (at least 100 ml). The capsule can be swallowed at any convenient time, regardless of the meal. On average, the course of treatment takes 7 to 10 days. In the treatment of gonorrhea, a single dose of 1 capsule (400mg) is sufficient.

Suprax Solutab

It is recommended to swallow the tablets whole with a large volume of liquid, or dissolve in a small volume of cool boiled water and drink immediately. For adult patients and adolescents over 12 years old, weighing more than 50 kg, the daily dosage is the same as for capsules. That is, one tablet can be taken at any convenient time of the day, regardless of food.

Suprax for children and adolescents weighing from 25 to 50 kg is taken in a dosage reduced by half - 1/2 tablet (200 mg) once a day.

The duration of the course of therapy depends on the type of disease. With mild urinary tract infections in women, the duration of taking the medication is from 3 to 10 days; in the treatment of pyelonephritis or cystitis, the course of therapy can be extended to 14 days. In men, the treatment of such pathologies takes from 7 to 14 days. Treatment of uncomplicated gonorrhea takes only one day, recovery occurs after a single dose of the tablet (400mg).

How many days should a child take Suprax for the treatment of ENT diseases? It all depends on the severity of the symptoms and the general condition of the patient. On average, children and adults take an antibiotic for 7 to 14 days to treat a respiratory tract infection. At the same time, both adults and children need to continue taking pills for another 1-2 days after the body temperature returns to normal, and all symptoms of infection disappear.

Suspension Suprax

The drug in the form of a suspension is intended for the treatment of children aged 6 months to 12 years. The dosage of the medicine is calculated by the doctor individually, taking into account the body weight and age of the little patient. The calculation is based on a ratio of 8 mg / kg weight. The calculated dose is given to the child once a day or divided into two doses.

How much water to add to the Suprax suspension and how to properly dilute it? After opening the package, shake the bottle with granules, open the lid, measure 40 ml of cool boiled water with a syringe and gradually, in 2 stages, add it to the preparation. During the introduction of the liquid, the bottle must be shaken to achieve a homogeneous state of the suspension. For the complete dissolution of the granules, 5 minutes is enough, after which the finished suspension can be given to the child.

For babies from 6 to 12 months, the daily dose of the drug is 2.5-4 ml. It can be given in one go or divided into two doses (morning and evening).

For children from 2 to 4 years old, a single dose of the suspension is 5 ml (1 measuring spoon). After 5 years, the child can be given from 6 to 10 ml of suspension per day. How many days should a child take Suprax in suspension form? On average, the duration of treatment for streptococcal infections is at least 10 days. With angina, the course of treatment takes from 7 to 14 days.

Contraindications

The modern antibiotic has few contraindications. It is not prescribed for hypersensitivity to antibiotics of the penicillin and cephalosporin series, with impaired renal functions, renal failure, pseudomembranous colitis (including anamnesis). With extreme caution and under the supervision of a physician, Suprax is used in elderly patients and young children.

Suprax during pregnancy can be prescribed only if the intended benefit to the mother outweighs the possible risks to the developing fetus. In practice, gynecologists quite often prescribe a cephalosporin antibiotic to pregnant women, since this is the safest option compared to other antibacterial agents.

If there is a need to use the drug during lactation, the baby should be temporarily transferred to artificial mixtures. You can return to breastfeeding one day after the end of the antibiotic intake.

Adverse Reactions

Suprax is well tolerated by patients and rarely causes adverse reactions. The most common of these are ailments associated with the digestive system. During treatment, you may experience nausea, dry mouth, lack of appetite, vomiting, abdominal pain, flatulence, constipation or diarrhea.

Symptoms of glossitis, stomatitis, enterocolitis, dysbiosis are possible. In the course of treatment, there is a violation of blood counts, headaches, dizziness, tinnitus, shortness of breath. Sometimes hypovitaminosis develops, renal function worsens, in rare cases, symptoms of nephritis or acute renal failure occur.

With individual intolerance, allergic reactions are observed (hyperemia, pruritus, urticaria, temperature increase), in exceptional cases, dangerous conditions develop - Quincke's edema, anaphylactic shock.

An overdose of the drug increases the severity of side effects. To relieve unpleasant symptoms, gastric lavage and the intake of sorbents (activated carbon, Polysorb) will help.

Additional recommendations

Long-term use of Suprax can lead to dysbiosis, provoke the development of pseudomembranous colitis and severe diarrhea. Therefore, in the course of treatment, all medical recommendations should be strictly observed and the drug should not be used longer than the specified period.

It should be borne in mind that the use of diuretics at the same time in Suprax slows down its excretion by the kidneys, which can lead to an increase in the concentration of cefixime in the blood. Antacids slow down the absorption of Suprax - the time interval between taking these medications should be 2-4 hours.

Analogs

Among the structural analogs of Suprax are the following antibiotics:

• Pancef;
• Ixim Lupine;
• Ceforal Solutab;
• Cefspan.

Among other drugs with a similar therapeutic effect, but with a different active substance, Sumamed funds are best suited, Amoxiclav, Lendatsin.

Price

The price for Suprax depends on the form of the drug and the manufacturer. The average cost of an antibiotic in pharmacies is:

1. Suprax capsules 400mg (6pcs) - from 680 rubles;
2. Suprax Solutab tablets (7pcs) - from 800 to 1000 rubles;
3. Suprax in granules (suspension) - from 550 to 700 rubles.

Feedback on application

The overwhelming majority of reviews about Suprax are positive. Patients note the high efficiency of the antibiotic in the treatment of severe infectious diseases, ease of use (1 time per day) and the possibility of using it in young children. The disadvantages of the drug include high cost and side effects.

Review number 1

My son, at the age of 3 years, was prescribed Suprax suspension for the treatment of prolonged bronchitis. At first they offered to do antibiotic injections, but I refused. The son is very difficult to endure such manipulations.

But he drank a sweetish suspension with a strawberry smell without objection. We liked this drug very much. Firstly, you need to take it only once a day, and secondly, the medicine very quickly eliminated all the symptoms of the disease.

Marina, St. Petersburg

Review number 2

Suprax took capsules for cystitis 1 piece per day. It is very convenient, you can drink the medicine at any time, and regardless of the meal. The antibiotic is expensive, but it justifies the price.

Quickly relieves all unpleasant symptoms and provides recovery in just 5-7 days. And the side effects of the drug are not as many as those of other antibiotics.

Antonina, Moscow