Kenalog. The price of 1 ampoule, instructions for use, where to buy injections, reviews

An effective medication Kenalog with anti-inflammatory and antihistamine properties helps to quickly eliminate the acute symptoms of various pathologies. The price of 1 ampoule of the drug is high, so not every patient will be able to use it. Despite the cost, the drug is effective, and when used correctly, it does not provoke negative reactions.

Terms of dispensing from pharmacies, drug price

The drug is currently dispensed in pharmacies by prescription from a doctor, which is explained by the strong effect and danger of self-administration.

The cost of 1 ampoule of the drug is approximately 150-200 rubles. This price is considered high, but the effectiveness of the medication fully justifies it.

Composition and form of release

The pharmaceutical is available to patients in the form of a suspension or solution for parenteral use and tablets for oral use. The solution is packaged in transparent colorless glass ampoules. The liquid is transparent and colorless, has no sediment and foreign inclusions. Ampoules are packaged in special plastic contour cells, 5 pieces each.

An individual cardboard box contains detailed instructions and 5 ampoules with the product. The tablets are of a standard size, packaged in blisters of 10 pieces. Placed in cardboard boxes, along with instructions. The composition of the product in any dosage form contains the triamcinolone acetonide component, which has the main therapeutic effect on the body.

The solution contains auxiliary ingredients:

• Benzyl alcohol.
• Polysorbate.
• Sodium chloride.
• Water for injections.

The tablets also contain additional substances in the form of magnesium stearate, talc, starch. They also contain lactose and povidone. Additional ingredients in the composition of tablets and solution do not have a therapeutic effect.

Principle of operation and efficiency

Kenalog (the price of 1 ampoule is considered very high) has pronounced anti-inflammatory and antihistamine properties. The active component of the composition belongs to the group of glucocorticosteroids, that is, it has an effect quickly, and the effect lasts for a long period.

After the active ingredient enters the bloodstream, the patient almost immediately feels an improvement, itching and burning are eliminated. These symptoms usually appear with an allergic reaction to food, medications, and other substances. After the initial application, complications almost do not occur, and long-term treatment is usually not required, which is considered an advantage of the remedy.

The active ingredient also helps to eliminate the signs of tissue inflammation.

The medication has several effects on the body at once:

• Its principle of action is based on the ability to inhibit the production of substances, which triggers an immune response in the form of an allergic reaction.
• Against the background of this inhibition, patients do not develop edema of the mucous membranes and skin, and severe itching and other symptoms are prevented.
• The active ingredient suppresses the patient's immune system, which helps to avoid a pronounced reaction.
• The drug also has anti-toxic and anti-shock properties, helps prevent the appearance of symptoms that threaten the patient's health. For example, with angioedema, the patient's condition deteriorates greatly, and the use of the drug helps to normalize it.

  

The medication does not affect the level of endorphin in the blood, but suppresses the secretion of certain hormones by the thyroid gland.

A positive property of the agent is considered to stimulate the production of red blood cells, which prevent tissue and brain hypoxia by delivering a sufficient amount of oxygen. Against the background of an increase in the number of red blood cells, a decrease in the level of protein in the blood plasma is observed.

Additional actions of the tool:

• Increases cholesterol levels through the processing of triglycerides.
• Stimulates the rapid absorption of carbohydrates in the digestive tract.
• Promotes the retention of sodium and water ions in the body.
• Leads to intensive excretion of potassium ions.
• Leads to excessive leaching of calcium from bone tissue with prolonged use in high doses. Against the background of this process, pathologies of the musculoskeletal system often develop.
• It inhibits the production of cytokines, which provides an immunosuppressive effect.
• Reduces the risk of scarring, which often remains on the skin after deep wounds have healed.

The anti-inflammatory effect of the drug is achieved due to its ability to suppress the release of substances that provoke the inflammatory process. Against the background of this action, there is a significant improvement in the condition.

After taking the drug inside, the active component is rapidly absorbed in the digestive tract. The substance is distributed through the systemic circulation and has a therapeutic effect. After that, it enters the liver, where it is processed. When administered parenterally, the agent bypasses the digestive tract and immediately enters the systemic circulation.

It works faster than oral pills. In case of impaired liver function, the processing of the active substance slows down. If the patient has kidney pathologies, it is possible for the ingredients of the composition to accumulate in the body, which can lead to the development of an overdose.

That is why, in case of severe kidney disease, dose adjustment and use only under the supervision of a doctor are required.

Usually, the withdrawal period of the active ingredient takes no more than 1 day. Most of the decay products are evacuated by the kidneys. The duration of processing and withdrawal of ingredients depends on the dosage and duration of use, the characteristics of the patient's body and age.

If a patient is diagnosed with acute or chronic pathologies of the mucous membranes of the digestive tract, the tablet dosage form is not used. It is better to prescribe a solution to the patient, but according to strict indications. Experts note the ability of the active substance of the drug to penetrate into breast milk.

Indications for use

Kenalog is usually used for allergic manifestations. The high price of 1 ampoule does not allow each patient to use the medicine for a long period, but this is usually not required.

The main indications for prescribing the drug:

• Allergic reactions against the background of the use of various medications.
• Anaphylactic shock against the background of aggravation of all manifestations of common allergies.
• Hemotransfusion shock during transfusion of blood, erythrocyte mass or other blood products to a patient. The disorder occurs even with the transfusion of suitable products, therefore, the use of potent drugs is required.
• Bronchial asthma with frequent and prolonged attacks that threaten the patient's life.
• Status asthmaticus, in which the patient experiences many attacks of bronchial asthma for a short period, and conventional remedies do not help to improve the condition.
• Systemic pathologies with damage to connective tissue. Quite often, the remedy is used for rheumatoid arthritis.
• Various types of shock, for example, cardiogenic, toxic, traumatic or burns, painful, postoperative.
• Poisoning of the body with toxins, poisonous substances.
• Acute disorders of the thyroid gland, accompanied by a critical decrease or increase in the level of hormones in the blood.
• Adrenal insufficiency or renal failure.
• Hepatic coma, acute hepatitis.
• Arthritis, synovitis, bursitis in the acute stage with severe pain and the development of the inflammatory process.
• Dermatological pathologies of a chronic nature. With psoriasis, eczema, dermatitis, total and nested alopecia, the drug helps to significantly improve the condition, prevents progression.
• Acute conditions of unspecified origin, accompanied by a decrease in blood pressure to a critical level.

The agent can be injected intramuscularly or into the joint cavity, depending on the disease for which it is used to treat.

Contraindications and adverse reactions

Kenalog (the price of 1 ampoule may differ in different pharmacies) is not prescribed when diagnosing intolerance to the components of the composition. Patients who have a history of allergy to glucocorticosteroids are rarely prescribed the drug.

Other contraindications include the following:

• Osteoporosis at any stage. The tool leads to the leaching of calcium from the bone tissue, so its use in such a violation can aggravate the condition.
• Chickenpox and herpes zoster. The use of the product is allowed only after the elimination of acute symptoms.

  

• Tuberculosis, proceeding in a mild latent form or accompanied by acute symptoms, a significant deterioration in the condition.
• Strongyloidosis in patients of different ages.
• Amoebiasis. With such a violation, the remedy can only be prescribed in an emergency.
• Bacterial and fungal diseases in the acute stage. After elimination of pronounced manifestations, the agent can be used with caution.
• The recovery period of the patient after joint surgery involving joint replacement.
• Arthrosis at an advanced stage. Usually at this stage, the joint is deformed, which is also considered an obstacle to therapy.
• Instability of the articular joint after surgery or injury.

With extreme caution, the agent is prescribed to patients with acute pathologies of the cardiovascular system.

The drug belongs to potent drugs, therefore it often provokes complications, worsening the condition and threatening the patient's life:

Organs and systems	Most common reactions
Nervous system	When using the drug for a long period, there is a risk of developing manic-depressive syndrome, even in the absence of a history of mental abnormalities. Some patients talk about disorientation in space and the appearance of hallucinations. The condition is aggravated by insomnia, seizures and increased intracranial pressure. In some patients, complications are mild, provoking anxiety, headache and dizziness.
Digestive organs	During treatment, the digestive tract suffers quite often, especially if there is a history of chronic pathologies. Patients note the appearance of pain in the stomach, exacerbation of pancreatitis, the development of intestinal pathologies, accompanied by bloating and other disorders.
The cardiovascular system	Increased blood coagulability and an increase in blood pressure indicators are observed in middle-aged and elderly patients. Young people do not suffer from such violations very often. The development of arrhythmia, bradycardia or tachycardia is observed.
Endocrine system	Thyroid disorders are considered the most common. In patients, the course of diabetes mellitus may also worsen, and adrenal gland activity is suppressed. The condition worsens significantly if treatment with the drug continues.
Exchange processes	An increase in body weight when using the product is often observed. A blood test reveals a decrease in calcium levels. Many patients talk about excessive sweating, sometimes weight decreases if there is no appetite.
Sense organs	With prolonged use of the drug, there is a deterioration in vision, the development of fungal and bacterial pathologies of the visual apparatus, a change in the structure of the cornea.
Skin and mucous membranes	The use of the drug increases the likelihood of developing fungal pathologies of the mucous membranes. If the drug is intolerant, an allergic reaction develops in the form of a rash, itching and peeling of the skin. Manifestations are usually mild, disappear after discontinuation of the drug.

Adverse reactions can be expressed with varying degrees of intensity, which depends on the individual patient. With prolonged use of high doses of the drug, an overdose develops. At the same time, the patient's blood glucose level rises, the general condition worsens, when examining urine, a specialist finds an increased glucose content in it.

An overdose is considered a reason for the immediate discontinuation of the drug and a visit to a specialist. Treatment is carried out in a hospital, it consists in the gradual withdrawal of the drug and the appointment of symptomatic therapy, taking into account the severity of certain manifestations.

Application and doses

Kenalog (the price of 1 ampoule of the drug is an obstacle to the use by many patients) in tablet form is taken orally. The suspension is injected intramuscularly or into the cavity of the articular joint, if necessary.

For adults

Adults take pills 3 pieces per day. The entire daily rate cannot be taken at one time, therefore it is divided into 3 doses during the day at approximately equal intervals. The maximum duration of treatment is 7 days. After that, the medicine is gradually canceled, reducing the dose daily.

Sometimes, with severe disorders, the daily rate rises to 4 tablets, but such treatment usually lasts no more than 5 days. The solution is administered intramuscularly no more than 1 time in 3-4 weeks. A potent remedy with frequent use can provoke complications.

Intramuscular injections are performed according to the standard scheme, using a long needle for deep injection. A single dosage is 1-2 ampoules, depending on the severity of the condition. In some cases, intra-articular injection is required, which is carried out only in a hospital under the supervision of a physician.

In the joint cavity, you can enter from 0.5 to 1 ml of the agent. The repeated procedure is carried out no earlier than 2 weeks later, but in most cases a break of 3-4 weeks is maintained. The course consists of 3 injections. Longer use is usually not required.

After intra-articular injection, the patient is under observation for at least a day. It is recommended to stay in a horizontal position during this period, reducing the load on the joint. Intravenous infusion of the solution is strictly contraindicated, even after dilution.

When the suspension is injected into the joint cavity, no solvents or pain relievers are used.

For children

The drug is almost never used for the treatment of children, since it has pronounced properties and often leads to complications. But the official instruction allows the appointment of patients over 12 years of age for strict indications.

The dosage is determined individually, the initial dose is 10 mg. 1 ml of the drug contains 40 mg of the active substance. The suspension is administered intramuscularly only in a hospital and under the supervision of a physician. The child's treatment usually does not last more than 7 days.

During pregnancy

During the period of breastfeeding and carrying a child, the drug is not prescribed. It can provoke serious complications for the mother and baby.

Only in rare cases, when an urgent need arises, specialists can use the solution.

Interaction with other drugs

Kenalog (the price of 1 ampoule starts from 150 rubles) should not be used simultaneously with other glucocorticosteroids. Negative reactions are observed when it is combined with acetylsalicylic acid, paracetamol, cardiac glycosides.

When taking pills, you should not use enterosorbents and antacids at the same time. They reduce the absorption of the active ingredient. There is no development of negative reactions with simultaneous use with many antibiotics, but with this combination, the risk of developing fungal pathologies increases.

Allowed to use in combination with antiarrhythmic, vascular drugs and some diuretics. The use of any medication in combination with Kenalog must be approved by a doctor in advance. It is forbidden to mix the product in one syringe with other solutions. An exception is Novocaine or Lidocaine.

Storage conditions and periods

During storage, it is important to protect the product from children and direct sunlight. The maximum storage time is 3 years. You can not put the product in the refrigerator, it is important to protect the tablets from moisture.

It is strictly contraindicated to use the medicine after the expiration date. The date of its production is indicated on the packaging.

The popular and effective medication Kenalog from the group of glucocorticosteroids has pronounced properties. The drug is prescribed for various allergic diseases and other conditions, despite the high price of 1 ampoule. Use as directed and adherence to all rules significantly reduces the risk of complications.

Video about the drug

Overview of ampoules Kenalog: