Hepatrombin gel. Instructions for use, price, reviews

Hepatrombin is a multifunctional agentwhich comes in the form of a gel or ointment. The instructions for use indicate that it is effective in the treatment of venous diseases, sports injuries and various skin inflammations. It is important to know that before you start using it, you need to consult a specialist.

Terms of dispensing from pharmacies, drug price

Hepatrombin belongs to non-prescription drugs, that is, when selling it, a pharmacy employee will not require the patient to have a special form prescribed by a doctor. However, this does not mean that you can self-medicate. It is better to first get a consultation with a phlebologist, surgeon or therapist, as well as undergo the necessary examination in order to establish an accurate diagnosis.

This drug is widespread in the pharmaceutical market, so it will not be difficult to find it. The cost of the gel depends on the form of release. So, a tube containing 20 g of the drug will cost the buyer 220-270 rubles, while 40 g of the drug will cost 370-420 rubles.

Composition, release form

Hepatrombin gel, the instructions for use of which describe in detail the composition of the drug, includes several active components:

Ingredient name	Amount per 100 g of gel
Heparin sodium	30,000 IU (medical units)
Allantoin	250 mg
Dexpanthenol	250 mg

In addition, the manufacturer has added a number of excipients to the drug.

Among them:

• Carbomer. Promotes a longer contact of the drug with the affected tissue.
• Disodium edetate, sorbitol, isopropanol, polysorbate. The compounds act as stabilizers and antioxidants.
• Purified water is added as a solvent.
• A complex of essential oils (oils of mountain pine needles and Scots pine, lemon oil). Plants are added to the composition to give the product a pleasant scent. In addition, these ingredients provide mild local pain relief.

The resulting gel is packed in aluminum tubes of 20 g or 40 g, which, together with the paper instructions, are placed in cardboard boxes with the name of the drug and the manufacturer's logo.

Operating principle

Instructions for use of the drug indicate 3 compounds simultaneously as active substances of Hepatrombin. They are responsible for the therapeutic effect of the gel.

It turns out that the drug is a complex medicine, where each of the components is responsible for its own therapeutic effect:

• Heparin sodium is a direct anticoagulant, prevents the formation of blood clots, prevents the process of gluing together and the formation of conglomerates. In addition, heparin improves blood circulation at the site of its application, relieves inflammation and tissue swelling.
• Allantoin has a pronounced anti-inflammatory effect, improves metabolism in the affected tissue, and stimulates cell division.
• Dexpanthenol accelerates tissue regeneration, enhances the penetration of heparin at the site of gel application.

Indications and contraindications for use

Due to its complex composition, Gepatrombin has a wide range of applications.

Its use will be relevant for diseases such as:

• Varicose veins of any stage. As a rule, in case of violation of the elasticity of the venous walls of stage 1, therapy is reduced only to the external use of the gel. In more severe conditions, Gepatrombin is recommended to be used in combination with venotonic drugs intended for internal use.
• Inflammation of the walls of the veins with the formation of clots of blood clots in them (thrombophlebitis).
• Vein thrombosis of the lower extremities.
• Sports injuries (sprains, sprains, blows, bruises, bruises). The use of the gel helps relieve pain, heal wounds and eliminate bruises.
• Inflammation of the tendon or its sheath (tendovaginitis).
• The presence of inflammatory infiltrates at the site of injury.
• An important note is that the use of Hepatrombin in the form of a gel for trophic ulcers of the leg is unacceptable. Patients with this pathology are recommended to use Hepatrombin G. These forms of release are somewhat different in composition, therefore, it is prohibited to use the gel with open wounds.

Despite the fact that the drug belongs to drugs for external use, its use is unacceptable in some cases.

These include:

• Skin lesions of a viral, bacterial or fungal nature. In the presence of infection, the use of the gel can aggravate the course of the process. If local inflammation remains after such a disease, Hepatrombin can be used only after the end of the main course of treatment.
• Hypersensitivity, intolerance to one or more components of the drug. Such patients will have to refuse treatment with Hepatrombin. Otherwise, a severe allergic reaction may develop. As a rule, it manifests itself in the form of skin rashes or itching, swelling of the mucous membranes. If such symptoms appear, treatment with the drug should be canceled and a doctor should be sought for help.
• Hepatrombin gel is also unacceptable to use in violation of the integrity of the skin, in the presence of open wounds or ulcers.

Terms of use

Hepatrombin gel, the instructions for the use of which indicate the dosage regimen and the duration of the course, may have several schemes of use. Her choice depends on the disease and stage of the process, as well as on the age of the patient.

With hemorrhoids

For the treatment of this disease, it is recommended to use Hepatrombin G, which is available in the form of an ointment. This form of release can be used rectally. The drug is approved for use from the age of 18. It is permissible for young patients to be treated with the drug only after consulting a pediatrician or pediatric proctologist.

The tool can be used for pathologies such as:

• hemorrhoids in any of its location (outside or inside);
• thrombophlebitis;
• the presence of fistulas, discomfort and itching;
• cracks.
• The ointment is also relevant for those patients who are preparing for surgery in the anorectal region.

Hepatrombin G is applied in a thin layer 3-4 times a day to the affected area, after the elimination of pain and other discomfort, the number of uses should be reduced to once a day, the duration of the course is 1 week. For the convenience of injecting the agent into the rectal cavity, you need to use a special tip that is included in the kit.

In addition, the pharmaceutical plant "STADA" produces Hepatrombin in the form of suppositories. This form of release is usually more convenient and effective in the treatment of hemorrhoids. Suppositories Hepatrombin G differ somewhat in composition from ointment and gel.

The active ingredients of the drug include:

• Heparin sodium. Eliminates blood clots, exudates, inflammation in the anus.
• Prednisolone acetate. Relieves inflammation and swelling, reduces itching, burning and pain in the anorectal region. Additionally, it has antiallergic effect.
• Lauromacrogol 600. It is a local anesthetic, promotes the adhesion of hemorrhoids and the cessation of blood supply in them.

The use of Hepatrombin in the form of suppositories should be carried out according to the following scheme: 1-2 times a day. The course of treatment can be from 5 to 10 days. It is important that the suppository is inserted into the rectal cavity after the act of defecation.

Suppositories are approved for use in patients over 18 years of age. At a younger age, half a candle should be used, but only after consulting a specialist.

With bruises and bruises

Hepatrombin gel can be used in the presence of bruises or bruises on the skin. The drug promotes rapid resorption of the hematoma. The tool can be used by patients over the age of 5 years.

The gel should be applied in a thin layer 1-2 times a day for 10 days. It is important that the drug is applied only to the site of the lesion. If symptoms (pain, inflammation) disappear earlier, treatment can be stopped.

If within 10 days the patient does not notice an improvement in his condition, he should seek medical help in order to exclude other possible pathologies (fracture, dislocation, rupture of ligaments).

With varicose veins

Varicose veins can have several stages of development. Despite this, the preparation in the form of a gel will be used in the same way.

The drug is approved for use in patients over 5 years old. To eliminate the symptoms of varicose veins, the gel must be applied in a thin layer twice a day for 7-10 days. In this case, it is important to avoid massaging or pressing movements.

If stage 4 varicose veins are observed, in which trophic ulcers may be present, it is better to use an ointment Hepatrombin G, which should be applied with light rubbing movements to the area around the wound, the frequency of use is 2 once a day.

With varicose veins, the drug Hepatrombin not only helps to eliminate the external symptoms of the disease, but also has a number of other therapeutic effects:

• moderately relieves pain syndrome;
• pleasantly cools the skin around the veins;
• relieves fatigue of the limbs.

From scars

Hepatrombin gel, the instructions for use of which do not indicate such experience of use, is still sometimes used to eliminate scars and scars on the skin. However, there is no proven effect in this pathology. First of all, the agent helps to eliminate edema, inflammation and the formation of blood clots, its active ingredients are not able to restore epithelial tissue, dissolving scars.

However, dermatologists sometimes practice prescribing this drug to treat scars in patients over 18 years of age, but only as an adjunct to primary therapy. To do this, the gel must be applied 2-4 times a day to the scar area. Massaging this area is not recommended. It is important to let the gel dry completely.

Some analogues, prices

There are several drugs on the pharmaceutical market that have a similar composition and a similar field of application. Hepatrombin gel has no absolute analogues, as it has a unique composition.

Partial analogs include:

• Lioton 1000, a gel for external use, produced by the Italian pharmaceutical company A. Menarini industrie Farmaceutiche Riunite, Italy.
• Heparin ointment, produced by Altayvitamins, JSC, Russia.
• Heparidex gel produced by Tatkhimfarmpreparaty, Russia.

In addition to the manufacturer, the presented drugs differ in active ingredients and cost.

Name	Active substances	Price
Hepatrombin gel	Heparin sodium, Allantoin, Dexpanthenol	20 g - 220-270 rubles, 40 g - 370-420 rubles.
Lioton 1000 gel	Heparin sodium	30 g - 340-390 rubles., 50 g - 430-480 rubles., 100 g - 780-830 rubles.
Heparin ointment	Heparin sodium, Benzocaine, Benzyl nicotinate	25 g - 60-110 rubles.
Heparidex gel	Heparin sodium, Dexpanthenol, Dimethyl sulfoxide	50 g - 270-320 rubles.

According to the data in the table, each of the drugs has its own unique composition, so their cost differs significantly from each other. Before making a choice, you need to understand the action of the medicine. This will help you choose a product with the best price-quality ratio.

As you can see, Lioton 1000 gel has only one active component in the form of sodium heparin, and the cost of the drug for 1 g is one of the highest. Compared to Heparin ointment, this price is about 5 times higher. At the same time, in Lyoton and Heparin ointment, the same concentration of sodium heparin (100,000 IU per 100 g of the drug).

In addition, the Russian-made ointment includes two additional active ingredients.

We are talking about such means as:

• Benzocaine. It is a local anesthetic, when applied externally, relieves pain.
• Benzyl nicotinate. Promotes the penetration of heparin into the vessel walls, expands them.

The closest to Hepatrombin in composition is the drug Heparidex, which is produced in the form of a gel. It also contains sodium heparin and dexpanthenol. Allantoin is excluded from the composition, but dimethyl sulfoxide is added.

This substance has a number of therapeutic actions:

• eliminates pain when applied topically;
• relieves inflammation;
• fights edema.

Since the drugs have similar compositions, their field of application is the same. Heparidex can serve as a substitute for Hepatrombin gel. To understand which of the drugs is cheaper, you need to recalculate the cost of 1 g of gel.

• Hepatrombin: 395 (average cost of a package) / 40 g (amount of gel in a package) = 9.8 rubles.
• Heparidex: 295/50 = 5.9 rubles.

It turns out that the purchase of Heparidex will cost the buyer almost 2 times cheaper. Another issue is the availability of drugs. The fact is that Gepatrombin is more popular and can be easily found in most pharmacy chains. Heparidex is also presented on the pharmaceutical market, but in search of it, you can bypass more than one pharmacy. A person who is experiencing discomfort or pain should not waste time looking for a drug. For this reason, buying Hepatrombin Gel can save the patient's time and nerves.

Thus, Hepatrombin remains a drug with an optimal price-performance ratio. In addition, any replacement of the drug is recommended to be carried out only after consultation with a therapist, phlebologist or proctologist.

Terms and conditions of storage

Hepatrombin gel, the instructions for use of which describe this item in detail, can be stored for 3 years from the date of production. But only on condition that it has never been used before. An open tube of gel can be used within 6 months after opening. The expiration date is indicated by the manufacturer on the side of the package.

Storage conditions for Hepatrombin gel are as follows:

• Temperature from 15 to 25 ° C. Deviation from these limits leads to the loss of the medicinal effects of the drug.
• Air humidity not higher than 65%. If the values ​​are exceeded, the product may delaminate, change its physical and chemical characteristics.
• A dark place, out of sunlight. In the light, the drug can heat up and decompose, as a result, its effectiveness decreases.
• Out of the reach of small children and pets. The best storage space is a tightly closed dry box that is high enough for children to reach. The tool is not intended for oral administration, otherwise it is fraught with the development of unforeseen consequences.

Since the gel can only be used for external treatment, it can be applied after shelf life, however, the manufacturer does not guarantee the therapeutic effect and the absence of side reactions. Therefore, if possible, it is better to replace the expired packaging of Hepatrombin with a new one. The fact that the gel is expired can be understood by some external signs.

These include:

• The appearance of color. Normally, the gel is colorless. If it acquires a yellow, white or green hue, this is an occasion to check its suitability.
• Stratification of the gel. This often happens when the temperature regime is violated or if it is exposed to direct sunlight. The homogeneous structure is lost, instead of it white layers appear, between which the liquid is observed.
• The appearance of lumps and a pungent, unpleasant odor also indicate that the drug has expired or the storage and transportation conditions have been violated.

When one or more signs appear, the gel must not be used.

Hepatrombin gel is an effective remedy for the treatment of varicose veins, thrombophlebitis, injuries and bruises, which has no complete analogues. Before using it, it is important to read the instructions for use in order to avoid possible complications.

Author: Olga Orlova

Video about hepatrombin

Hepatrombin gel - indications, video instructions: