Karipazim with a hernia of the spine. Reviews, ampoule price


  1. Form of release of ampoules Karipazim
  2. Composition of the preparation
  3. Pharmacological properties
  4. Pharmacodynamics and pharmacokinetics
  5. Indications for use
  6. Contraindications
  7. At what age can the drug be used?
  8. How does Karipazim help with spinal hernia?
  9. Instructions for the use of ampoules, dosage
  10. Side effects
  11. Overdose
  12. special instructions
  13. Drug interactions
  14. Analogs
  15. Terms, conditions of sale and storage
  16. Price
  17. Video about the drug Karipazim

In traumatology, neurosurgery and orthopedics, it is in great demand pharmacological agent Karipazim. The drug helps to achieve a positive therapeutic effect in spinal hernia, neuritis and radiculitis. Karipazim is a plant proteolytic enzyme agent.

The drug is based on antienzymes, which exhibit the properties of inhibitors that prevent the destruction of healthy cells in the body. Numerous reviews of neurosurgeons confirm that a plant-based medication helps to restore the damaged membrane of the intervertebral disc.

When used correctly, the drug allows you to achieve an anti-inflammatory effect, eliminates swelling of soft tissues, stimulates phagocytosis and blood circulation. Before buying a product, you need to consult a doctor to eliminate the likelihood of side effects.

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Form of release of ampoules Karipazim

Karipazim with a hernia of the spine (reviews of traumatologists and neurosurgeons indicate that with regular administration of the drug into the pathological the focus with the help of physiotherapy procedures increases the elasticity of the ligaments and cartilage tissue by 80%) should be prescribed by an exclusively qualified doctor. Only an individual course of treatment will help to cope with the extrusion of the core of the intervertebral disc into the spinal canal, which is caused by the violation of the integrity of the annulus fibrosus.

The drug is produced in glass ampoules, in which the concentration of the active substance can be 350 or 700 PE. Each bottle is closed with a rubber stopper and additionally crimped with aluminum caps. A pharmacological agent is sold together with instructions in cardboard boxes, each of which contains 10 or 50 ampoules.

Composition of the preparation

The medication contains only natural substances. Enzymes of plant origin are used as active ingredients, which are found in the milky juice of the melon tree (papaya):

  • Proteinase.
  • Papain.Karipazim with a hernia of the spine. Reviews, price
  • Peptidases (A, B) are enzymes of the hydrolase class.
  • Amino acids.
  • Lysozyme (an antibacterial agent of natural origin with a pronounced antimicrobial and antiparasitic effect).
  • Chymopapaines (A, B).
  • Carbohydrates.
  • Sodium, magnesium, potassium and calcium salts.

Pharmacological agent Karipazim is a white, odorless lyophilized powder. The finished medicinal solution is intended for topical application using physiotherapeutic procedures (electrophoresis).

Pharmacological properties

Karipazim with a hernia of the spine (reviews of traumatologists indicate that the components of the drug, when used correctly externally are not absorbed into the systemic circulation and do not have a negative effect on the body) helps to reduce the intensity of pain syndrome and improve the patient's quality of life, but at the same time does not stop the progression of degenerative changes in the intervertebral disks.

The pharmacological agent is produced on the basis of sulfhydryl proteolytic enzymes, due to which the completed course of therapy helps to achieve selective proteolytic activity, which is expressed in the hydrolysis of proteins of necrotic tissues and polypeptides. The drug does not affect the state of healthy tissues, which is due to the presence of protease inhibitors in the composition.

Among the main pharmacological properties of the drug Karipazim are:

  • Stimulates the formation of new blood vessels, improves blood circulation.
  • Relief of the inflammatory process.
  • Increasing the trophic role of the nucleus pulposus.
  • Elimination of soft tissue swelling.
  • Restoration of the natural turgor of the intervertebral disc, increasing its elasticity.
  • Stimulation of phagocytosis, without which it is impossible to eliminate pathogenic microorganisms.
  • Decreased hyaluronidase activity. This enzyme triggers the breakdown of hyaluronic acid, which is essential for maintaining joint mobility.
  • Stimulation of regeneration processes in soft tissues.
  • Increasing the intensity of collagen protein production.
  • Dissolution of necrotic tissue.
  • Scarring of the fibrous annular membrane of the intervertebral disc.

The annotation to the drug indicates that, provided that Karipazim is used by electrophoresis, it is possible to achieve selective accumulation of the drug in the affected intervertebral discs. The components of the drug undergo complete biotransformation in the liver.

Pharmacodynamics and pharmacokinetics

To achieve the maximum therapeutic effect from the use of Karipazim is possible only through electrophoresis procedures. Thanks to this, it is possible to stop the inflammatory process and reduce the intensity of the manifestation of the pain syndrome.

Under the action of the drug, the dead cells are gradually rejected from the intervertebral disc, which allows the body to activate tissue regeneration. After the completed therapeutic course, fibro-cartilaginous formation in the form of a flat round plate, connecting adjacent vertebrae, becomes smaller and softer, due to which it ceases to squeeze the nerve endings.

Karipazim is effective even in cases where the pathological process is running, since the drug helps to normalize the condition of the damaged intervertebral disc, as well as reduce the intensity of development hernia. The drug contains lysozyme, which restores blood circulation and improves nutrition in all parts of the spine.

Indications for use

Karipazim is used in traditional medicine not only for hernia of the spine, but also for the complex treatment of osteochondrosis, as well as burns. Patient reviews confirm the fact that in 99% of cases the drug does not cause side effects and helps to reduce the likelihood of further progression of the diagnosed disease.

Orthopedists, traumatologists and neurosurgeons recommend using Karipazim for the treatment of the following pathologies:

  • Schmorl's hernia. This is a vertical indentation of the cartilaginous tissue of the intervertebral disc into the cancellous bone of the vertebral body (above or below the disc).
    Karipazim with a hernia of the spine. Reviews, price
    Schmorl's hernia
  • Arthrosis and arthritis that affect large structures.
  • Discogenic sciatica. This is a clinical symptom complex due to degenerative-dystrophic changes, as well as secondary inflammation of the spinal roots in the lumbar and sacral spine.
  • Neuritis of the facial nerve. This is an inflammatory lesion of the nerve that innervates the facial muscles of one half of the face.
  • Periarthritis of the shoulder is an inflammatory disorder of the tissues that surround the shoulder joint.
  • Burns of the III degree. Karipazim helps to speed up the rejection of scabs, as well as to cleanse granulating wounds to eliminate remnants of necrotic tissue.
  • Cerebral, spinal arachnoiditis.
  • Flexion contracture of the fingers.
  • Diagnosed dental diseases. For example, pulpitis, chronic periodontitis, stomatitis, gingivitis, periodontal disease.

Karipazim is also included in combination therapy for the relief of aseptic inflammatory processes that develop as a result of soft tissue damage.


Despite the natural composition, not all patients can use the pharmacological agent Karipazim.

In the annotation to the drug, the manufacturer indicated the following contraindications:

  • Sequestration of a herniated disc.Karipazim with a hernia of the spine. Reviews, price
  • The period of bearing a child.
  • Foraminal sequestration location.
  • Lactation.
  • Individual intolerance to papaya.
  • Violation of the integrity of the skin at the site of the intended fixation of the electrophoresis pads.
  • The presence of an inflammatory process in the body.
  • Hypertension.
  • The period of exacerbation of kidney disease.
  • Increased body temperature.
  • Chronic heart failure.
  • Diseases of the skin.
  • Hyperthermia.
  • Childhood.
  • The presence of oncological neoplasms in the body.

It is forbidden to use Karipazim for intramuscular, intravenous and subcutaneous administration. Otherwise, if a pharmacological agent enters the mucous membrane of the gastrointestinal tract with a 99% probability of tissue degeneration, which will affect the rapid development of an attack of colitis or gastritis.

The drug is not prescribed to patients for the treatment of a diagnosed hernia in situations where the contents of the intervertebral disc have been sequestered. If, after using the medication, discomfort occurs, then it is recommended to rinse the problem area with warm water and apply a thin layer of Hydrocortisone ointment.

At what age can the drug be used?

Karipazim is not used in pediatrics. If a child is diagnosed with spinal diseases, then orthopedists and traumatologists prescribe safer pharmacological agents for the electrophoresis procedure. You can use the drug only from the age of 18.

How does Karipazim help with spinal hernia?

As a result of violation of the integrity of the annulus fibrosus, the nucleus of the intervertebral disc protrudes into the spinal canal, due to which the patient's condition is rapidly deteriorating against the background of the onset of painful symptoms. For the complex therapy of a hernia of the spine, electrophoresis procedures are indicated. In severe osteochondrosis, Karipazim at the physiological level acts as a stabilizer of the spinal motion segment.

Regular use of the drug helps to reduce the likelihood of further protrusion of the hernia and prolapse of the disc by 90%. The use of Karipazim allows you to normalize the work of all structures of the spinal column.

Medical data confirm that after the completed therapeutic course in more than 70% of patients, the condition stabilizes, thereby avoiding surgical intervention.

It is recommended to carry out electrophoresis procedures in medical institutions, exclusively under the supervision of qualified medical personnel.

Karipazim with a hernia of the spine. Reviews, price
Karipazim with a hernia of the spine

With regular use of Karipazim for the treatment of a hernia of the spine after the completion of the therapeutic course, the following results can be achieved:

  • Reduce the intensity of the manifestation of painful symptoms in radicular syndrome.
  • Fix the fibrous disc, stabilize the spinal motion segment.
  • Reduce the size of the hernia.
  • Normalize the protein composition of the cartilage tissue.
  • Eliminate spinal compression syndrome.

In laboratory conditions, it was proved that the drug Karipazim is made on the basis of papaya milky juice containing vitamin complexes, the use of which helps to prevent the development of osteochondrosis and reduce the likelihood of diseases of the musculoskeletal apparatus.

Instructions for the use of ampoules, dosage

Karipazim for a hernia of the spine (reviews of qualified traumatologists and orthopedists confirm that the drug helps to reduce the hernia and make it more soft, which in most cases is quite enough to release the nerve endings that it pinches) is used for procedures electrophoresis. Thanks to physiotherapeutic procedures, the drug penetrates as quickly as possible into the focus of pathological changes.

To achieve a positive therapeutic effect, a pharmacological agent must be used in a course. The number of procedures is determined by the attending physician, taking into account the age, general condition of the patient and the form of the disease diagnosed in him.

To eliminate pain and improve the mobility of the musculoskeletal system, 3 courses are most often prescribed, each of which includes up to 35 sessions of electrophoresis. Each procedure lasts 15-20 minutes. The break between courses should be 1-2 months.

The electrophoresis procedure is carried out according to the following algorithm:

  • It is recommended to prepare a solution of Karipazim in 2-7 minutes. before the intended use, since with a longer preparation, papain begins to break down under the influence of oxygen. Not more than 100 mg of the drug should be diluted in 10 ml of saline. To enhance the positive therapeutic effect, you can additionally add 1 drop of Dimexide.
  • The pads of the physiotherapy apparatus must be impregnated with a medicinal solution. It is recommended to use Euphyllin together with Karipazim. A pad with a positive electrode is impregnated with a solution based on Karipazim and applied to the lumbar region. This technology for carrying out the electrophoresis procedure is appropriate for lesions of the lumbar spine. A pad with a negative electrode is impregnated with Eufillin 2.4% and placed under the abdomen. This method of treatment is called transverse. In medicine, the placement of negative electrodes on the shoulders, hips, and also at the point of exit of the sciatic nerve is also practiced.
  • The electrodes are fixed and connected to the apparatus.

The pads soaked in the medicated solution should be heated to 37-39 C. The current must be between 5 and 15 mA.Karipazim with a hernia of the spine. Reviews, priceKaripazim with a hernia of the spine. Reviews, price

Special therapeutic exercises, which are designed to strengthen the muscles of the abdomen, back, neck and extremities, help to enhance the final therapeutic effect. With proper exercise, the condition of the muscular system can be improved and the spine stabilized so that the patient can better cope with daily tasks.

If necessary, the patient can also be prescribed massage, the use of medications and manual therapy. It is additionally recommended to visit the pool. For hernia of the spine, arthrosis and protrusion, the drug Karipazim is used according to the general scheme. Only the attending physician can make changes to the treatment regimen, since self-medication is fraught with the development of complications and a deterioration in the patient's quality of life.

Side effects

Karipazim with a hernia of the spine (patient reviews confirm that the price of the drug is justified by its high efficiency in the fight against pain syndrome, which occurs due to the protrusion of the intervertebral disc outside the spine and compression of the nerve roots) can, in isolated cases, provoke the occurrence of side reactions.

With increased sensitivity of the body to the milky juice of papaya, the patient may develop an allergic reaction, which will be accompanied by the following symptoms:

  • Increased body temperature.
  • Itching, burning at the site of application of electrophoresis pads that have been soaked in Karipazim solution.
  • Chills.
  • General malaise.
  • Headache attacks.
  • Local edema of soft tissues.
  • Hives.
  • Redness of the skin.

The occurrence of the listed symptoms indicates the presence of hypersensitivity of the body to the composition of the drug. To normalize the condition, you need to abandon the further use of the drug. Antihistamines can help eliminate the symptoms of an allergic reaction. Only the attending physician can choose a safe analogue of Karipazim.


In traditional medicine, no cases of overdose of Karipazim have yet been recorded. The drug is safe, since when used correctly it does not affect the functioning of internal organs.Karipazim with a hernia of the spine. Reviews, price

The manufacturer of the pharmacological agent admits the likelihood that too frequent electrophoresis procedures can provoke a rapid deterioration in the patient's well-being. In this case, it is necessary to seek advice from the attending physician, who, if necessary, will prescribe symptomatic treatment.

special instructions

Between 5 and 8 electrophoresis procedures, 85% of patients experience a temporary exacerbation of the diagnosed disease of the musculoskeletal system, but drug withdrawal is not required. The condition is necessarily normalized after 3-5 procedures. To achieve the desired therapeutic effect, it is important not to discontinue treatment.

So that the therapy of a hernia of the spine using electrophoresis does not provoke complications, the patient must first undergo a comprehensive examination of the body. The patient is prescribed magnetic resonance imaging so that the rheumatologist can assess the condition of the spine.

After the completion of the first course of electrophoresis, consisting of 30 procedures, it is recommended to additionally strengthen the back muscle corset by myostimulation of the paravertebral muscles. The standard course consists of 12 procedures, which are carried out with a frequency of 1-2 times a week. Daily gymnastics will also help to maintain muscle tone.

Drug interactions

It is recommended to include Karipazim in the combined drug therapy of spinal diseases. The feasibility of using several drugs at once can be assessed only by the attending physician. It is strictly forbidden to self-medicate, since an incorrectly selected therapy for a hernia of the spine is fraught with a complete loss of the ability to control the lower extremities.


If there are contraindications to the use of the drug Karipazim, it must be replaced with a safer drug. It is preliminarily recommended to consult with the attending physician, who, based on the collected anamnesis, will draw up an individual treatment regimen and select a safe analogue.

Drug name Description
Chymotrypsin It is a proteolytic drug of protein origin. The drug helps to activate the processes of cleavage of necrotic tissues and fibrous formations. Chymotrypsin is prescribed to patients with the following diseases: thrombophlebitis, periodontal disease, iridocyclitis, spinal hernia, osteomyelitis. Contraindications for use: liver cirrhosis, decompensated forms of tuberculosis, pancreatitis, heart failure. For electrophoresis procedures, it is recommended to use 10 mg of chymotrypsin powder, which must be dissolved in 20 ml of distilled water. A safe treatment regimen is drawn up by the attending physician on an individual basis. The tool costs 810-1080 rubles.
Trypsin It is an effective drug of proteolytic principle of action. Trypsin exhibits a pronounced anti-edematous and anti-inflammatory effect. When used correctly, the drug breaks down fibrous formations, dead areas of soft tissues and viscous exudate. The pharmacological agent is effective in the fight against the following diseases: acute thrombophlebitis, iritis, odontogenic osteomyelitis, pleural empyema, bronchiectasis, postoperative atelectasis. In traditional medicine, Trypsin is also used for electrophoresis procedures when a patient is diagnosed with a hernia of the spine, osteochondrosis, bursitis. The drug should not be used in the following cases: renal failure, oncological neoplasms, hypertension, disorders of the cardiovascular system. To achieve a positive therapeutic effect, 10 mg of Trypsin powder must be dissolved in 20 ml of distilled water. Negative electrode pads should be impregnated with the agent. For the treatment of a hernia of the spine, you need to undergo 7-15 electrophoresis procedures. The exact treatment regimen can only be prescribed by the attending physician. The product costs in the range of 790-883 rubles.
Karipain It is an enzymatic drug with proteolytic properties. The drug is produced in the form of a powder. In the annotation to the pharmacological agent, the following indications for use are indicated: herniated intervertebral discs, carpal tunnel syndrome, sciatica, osteochondrosis. Karipain is forbidden to use in case of acute inflammation of connective tissues and complete prolapse of the disc nucleus. To achieve a positive therapeutic effect, the drug powder must be dissolved in saline by adding a few drops of the anti-inflammatory drug Dimexide. Karipain is used for electrophoresis. The standard course of therapy consists of 30 procedures. The medicine costs 586-950 rubles.

To effectively treat a hernia of the spine and prevent the development of complications, patients should avoid strenuous physical activity. At the same time, it is important to constantly maintain muscle tone.

Terms, conditions of sale and storage

The drug Karipazim is sold only with a doctor's prescription. Store the drug in a dry, well-ventilated place, out of the reach of children and direct sunlight. The air temperature in the room should be between +15 and +25 C. The shelf life of the drug is 18 months. After this period of time, the unused medicinal product must be disposed of.


The drug Karipazim is used in traditional medicine for performing electrophoresis procedures for spinal hernia. The cost of the drug varies from 88 to 200 rubles.

Numerous reviews of patients and traumatologists confirm that a pharmacological agent has not only affordable price, but also high efficiency in the fight against burns, osteochondrosis and dental diseases. For safe treatment, the patient must first undergo a comprehensive examination of the body and consult with the attending physician in order to avoid side reactions and complications.

Video about the drug Karipazim

Treatment of hernia by electrophoresis of karipazim:

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