Osteogenon (Osteogenon). Price, reviews, instructions for use

The drug Osteogenon has been popular among people suffering from deficiency of calcium and phosphorus in bone tissue. The price of the original medicine or its analogs is justified by the natural composition, the efficiency of the process of resuming phosphorus-calcium metabolism, which can be judged by the positive feedback from patients.

The medication is prescribed for the treatment of pathologies of the spine, prevention and control of osteoporosis. In case of violation of the strength of bones, Osteogenon allows the missing minerals to be absorbed faster by the body.

Selling features

The production of Osteogenon is carried out by the French pharmaceutical company Pierre Fabre Medicamen. Its cost in the territory of the Russian Federation can be considered above average, but the cost of the medicine fully compensates for its effective properties. Today the price tag ranges from 728 rubles. (St. Petersburg) and from 940 rubles. (Moscow). In other regions of Russia, prices do not differ much.

You can buy a medicine on a natural basis both in stationary pharmacies and reserve / purchase in one of the online pharmacies. Here the buyer acts solely on the basis of their preferences.

The advantage of online pharmacies is that they allow you to monitor all inpatient drug sales establishments in the community where the patient lives. Based on the data obtained, Osteogenon can be found at the lowest cost, and you can arrange home delivery (provided that such a service is provided).

A drug that affects bone mineralization is dispensed only if there is a prescription from the attending doctor. For a sale without this document, Russian law provides for liability.

Active ingredients

Osteogenon (price, reviews, analogues of the drug are discussed in this article) is produced and sold in the form of oblong, biconvex tablets. Each capsule is covered with a light yellow protective shell, which dissolves in the intestinal / gastric juice. In a cardboard box, as a rule, there are 4 blisters with tablets (10 pieces each).

The active ingredient is represented by an ossein-hydroxyapatite compound.

It consists of the following components:

• non-collagen peptides and proteins;
• ossein, which stops resorption;
• calcium, which prevents hormone-related bone loss;
• phosphorus, which fixes the elements entering the body;
• collagen proteins.

In addition, Osteogenon contains a number of auxiliary substances: potato starch, magnesium salt and stearic acid, microcrystalline fiber, silicon dioxide. For the manufacture of a protective shell, hypromellose, talc, food additive E172 (iron oxide), which gives a yellow color, and macrogol are used.

Operating principle

The healthy functioning of the human body directly depends on the level of calcium in it. There is a whole symptomatic picture that indicates a deficiency of this mineral. It is shown in the table below.

Symptom	Description
Bone fractures	Hydroxypatitis deficiency is characterized by a slight tendency of bone tissue to damage.
Insomnia	Calcium-deficient patients find it difficult to fall asleep, at night they are disturbed by frequent awakenings for no apparent reason.
Pain in joints and bones	These symptoms indicate the development of arthritis and arthrosis. The first is always an inflammatory process, and the second refers to metabolic pathologies.
Chipped teeth and cracked tooth enamel	The strength of the teeth, the color of their outer protective shell is violated. Caries and various odontogenic infections also develop.
Hair problems	People have to deal with brittleness, dryness and hair loss.
Abnormal heart rhythm	With a calcium deficiency, blood pressure often rises, symptoms of hypertension appear.
Muscle spasms	Severe cramps appear in the calves, arms and thighs.
Severe recurrent pain	As a rule, they are characteristic only for women, since they occur shortly before the onset of the menstrual cycle.

Osteogenon, the price of which is justified by effective bone mineralization, is able to stimulate bone-forming cells and inhibit osteoclasts. Reviews of the original drug and its analogues indicate that hydroxyapatite is completely absorbed from the gastrointestinal tract.

Hormone-mediated bone resorption is prevented by inhibiting the production of parathyroid hormone. Hypercalcemia will be unable to reach its peak due to the slow release of calcium from hydroxyapatite.

Phosphorus takes part in the crystallization of the main component of bone tissue. It also fixes calcium in the bones and prevents its rapid excretion from the body by the kidneys. Osteogenesis (the process of bone formation) is activated by ossein, the main organic component of bone tissue. This component not only inhibits resorption, but also increases the activity of osteoblasts, normalizes the production of fibrillar protein.

The bone matrix is ​​formed by collagen type 1, which is part of Osteogenon. And the protein from the family of insulin-like growth factors is responsible for stimulating the synthesis of osteocalcin and collagen.

Recommendations for taking the drug

The drug, which is part of the group of regulators of calcium-phosphorus metabolism, is taken orally.

Doctors prescribe it if the patient has at least one of the following pathologies in the patient's history:

• Primary osteoporosis. A disease that affects the connective tissue, which is most susceptible to the bones of the legs and arms, as well as the spine. It can be senile, climacteric, or occur during menopause.
• Secondary osteoporosis. It is a derivative in the form of complications of endocrine, hematological, inflammatory diseases. It also occurs during (or after) steroid drug therapy.
• Disruption of the exchange of calcium and phosphorus in the body, provoked by pregnancy or breastfeeding.
• Genetically determined anomaly of tissue development, which is characterized by defects in fibrous structures, a change in the ratio of collagen fractions (connective tissue dysplasia).
• Osteopenia, in which the number of osteocytes in the bones decreases, their structure changes. The density and volume of bones is lost, they become thinner, become fragile.

Osteogenon (price, reviews, analogues of the drug are listed in the article) doctors recommend taking for scoliosis, rickety deformation of the musculoskeletal system, dysplasia of the joints.

Today it is hardly possible to find a drug whose composition would not be capable of causing an allergic reaction due to individual intolerance to the components.

The instructions for the use of Osteogenon indicate that it is strictly forbidden to take it to patients who, in addition to allergies, have a history of:

• kidney stone disease;
• increased filtration of calcium in the tubules of the nephron (hypercalciuria);
• syndrome of impairment of all kidney functions, resulting in a disorder of nitrogenous, water or electrolyte metabolism;
• hypercalcemia.

A person who is on hemodialysis, that is, undergoes extrarenal blood purification procedures in acute / chronic form of renal failure, cannot use Osteogenon either. The same applies to patients under the age of majority. If therapy cannot do without the use of the drug, the attending doctor will individually adjust the dosage based on the test results.

Laboratory studies have shown that the ossein-hydroxyapatite compound during pregnancy does not have a toxic effect on the woman's body or on the fetus. Also, it does not harm the baby during lactation, since even its potential penetration into breast milk when taken in recommended doses is absolutely harmless.

Reception scheme

The yellow-coated tablets are taken orally, with or without food. There is no need to chew or grind the capsules, it is enough to drink water so that the medicinal substances, when absorbed, begin to act on the focus of the disease. The daily dose is prescribed by the doctor depending on the symptomatic picture, ultrasound examination or tests.

To combat systemic osteoporosis of the spine (senile or climacteric), it is necessary to take at least 2-4 capsules per day. The duration of treatment for such a disease can range from 6 months to a year. In case of complete or partial violation of the integrity of the bone without damaging the skin, the doctor prescribes 2 tablets three times a day. Therapy for fractures lasts an average of 90 days.

Other medical indications require that the dosage be halved. For example, in order to regulate the calcium-phosphorus balance during gestation / breastfeeding, the daily dose should be no more than 1 capsule.

It is strictly forbidden to combine treatment with Osteogenon with the use of alcoholic beverages. And exceeding the daily dose of the drug is fraught with headache, disruption of the gastrointestinal tract. The accompanying symptoms in this case are nausea, constipation, vomiting.

Sometimes, in case of an overdose, patients are diagnosed with chronic poisoning with the following symptomatic picture:

• febrile syndrome;
• increased urine production;
• sudden weight loss;
• the formation of kidney stones;
• dehydration with intense thirst.

Overdose is usually diagnosed by hypercalcemia - high levels of calcium in the body. Usually, patients who have exceeded the dose of the drug are washed with the stomach, the drug is removed with an enema or drugs used to treat constipation.

Osteogenon (price, reviews, analogs are recommended to be studied before using the drug) cannot be used simultaneously with antibiotics belonging to the polyketide class. Tetracyclines are capable of affecting the absorption of biologically active components, due to which the body will not receive the required dose of the ossein-hydroxyapatite compound. To avoid such problems, it is necessary to take a break of 3-4 hours between taking Osteogenon and the antibiotic of the tetracycline group.

Some analogues, prices

There are not many Osteogenon generics on the shelves of pharmacies today, and the composition of most of them differs from the original, although the action is identical. For the production of analogs intended for the treatment of bone pathologies, either calcium carbonate or citrate is used. The following are several drugs that are also effective at replenishing calcium stores in the body.

Calcimax

The composition of this bioactive complex includes calcium, magnesium and amino acids, which are involved in the formation of tissues (bone, nerve and connective). Calcimax also contains manganese, which is involved in phosphorus metabolism, effectively contracting and relaxing muscles. Carbohydrate metabolism is accelerated by chromium, which maintains optimal blood sugar levels. Auxiliary active ingredients are vitamin D, C and chondroitin sulfate.

In addition to osteochondrosis, hypothyroidism, rheumatoid arthritis, Calcimax is effective in radiation sickness, neurodermatitis, eczema and hemorrhagic vasculitis. Dentists sometimes prescribe it to strengthen the outer protective membrane of the coronal part of the patient's teeth. The cost of a jar containing 45 tablets is 765 rubles, and for 90 capsules you will have to pay 1,400 rubles.

Osteoton

Complex homeopathic medicine, which is produced in the form of granules. There are several main active ingredients - calcium, rue extract and strontium carbonate.

In addition to the fact that Osteoton promotes bone growth, stimulates the processes of osteogenesis, it also has an anti-inflammatory effect.

It is prescribed if there are such indications:

• purulent-necrotic processes developing in the bones / bone marrow (osteomyelitis);
• osteoporosis;
• progressive destruction of the structure of the alveolar process of the upper jaws;
• closed fractures, dislocations;
• inflammation of the mucous bags in the joints (bursitis).

This generic drug differs from Osteogenon in that it can be given to children under 18 years of age. The medication has practically no side effects. Only in case of individual intolerance, a rash may appear on the skin, accompanied by severe itching. The average cost of Osteoton is 450 rubles.

Growth-Norm

The medicine is able to influence metabolic processes, regulate the process of intake and distribution of minerals in organs and tissues. Rost-Norma is effective for bone tissue repair after surgical treatment of the primary form of hyperparateriosis. Its advantages include strengthening the ligamentous apparatus of the joints, normalizing the intestinal microflora, the ability to have an immunomodulatory effect.

It is dispensed in pharmacies without a prescription and is prescribed by doctors for the prevention / treatment of bone formation disorders. Indications for use also include the treatment of caries, scoliosis, the normalization of phosphorus-calcium metabolism in adolescents. You can buy Rost-Norm in Moscow pharmacies for 1260 rubles.

Actonel

Osteogenon (price, reviews, analogues of the drug are in the public domain) can be replaced with Actonel. Of all the generics, this bone resorption inhibitor for osteoporosis is one of the most expensive. The price of one package is 3 690 rubles.

Each tablet contains 5 mg of the active ingredient - sodium risedronate. After 30 days of treatment, the level of biochemical markers of bone metabolism in the patient's body decreases. The risk of developing compression fractures of the vertebrae is minimized. In women who go through menopause, the risk of injury to the proximal femur is reduced.

It is strongly not recommended to take Actonel in case of impaired renal function, substance metabolism, during the period of bearing a child. Contraindications are lactose intolerance, stomach ulcers, narrowing of the esophagus.

Terms and conditions of storage

The result of Osteogenon therapy depends on how correctly a person will take it and follow the rules for storing the drug. The metabolism regulator in bone and cartilage tissues must be stored for no more than 4 years in a place where a small child or pet cannot reach. In the place where the medicine is stored, the optimum temperature should fluctuate between 15-30 ° C.

If you take a drug that has already expired, you may experience shortness of breath, increased blood pressure, and dizziness. In such a situation, you need to immediately call an ambulance or rinse your stomach yourself (if the poisoning is not severe).

Osteogenon is an effective pill for the treatment of bone and musculoskeletal diseases. Its price is justified by the result, as evidenced by the reviews of satisfied patients, and analogues are no less popular. But without first consulting a doctor, it is not recommended to take capsules, so as not to worsen the general condition. The doctor will draw up the optimal therapy regimen and, thereby, minimize the risk of various side effects.

Video about the drug Osteogenon

Instructions for the use of Osteogenon: