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Nolpaza. Indications for use, instructions, price, reviews

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Content

  1. Release form of Nolpaza
  2. Composition of the preparation
  3. Pharmacological properties
  4. Pharmacodynamics and pharmacokinetics
  5. Indications for use
  6. Contraindications
  7. At what age can the drug be used?
  8. Instructions for use, dosage
  9. With gastritis
  10. With pancreatitis
  11. With VSD
  12. Side effects
  13. Overdose
  14. special instructions
  15. Drug interactions
  16. Analogs
  17. Terms, conditions of sale and storage
  18. Price
  19. Video about the drug Nolpaza

Nolpaza is an effective medicine for the treatment of pathologies of the digestive system. Indications for its use are assessed after identifying the neglect of the disease, the presence of concomitant deviations. The medication is considered very effective, is well tolerated by patients of different ages and helps to eliminate the symptoms of diseases in a short period.

Release form of Nolpaza

The drug is sold in the form of tablets for oral use. They are small, enteric coated, packaged in foil plates of 10 pieces. In a small package made of cardboard, 2 plates with tablets are packed, as well as a description for the drug. It indicates the nuances of the application and possible complications during therapy.

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The drug is also produced as a white lyophilisate for solution preparation. It is administered parenterally as needed. The lyophilisate is placed in small transparent glass containers. Each of them is in an individual cardboard package, a description is attached to it, as well as to the tabletting agent.

Composition of the preparation

Nolpaza (indications for the use of the medication are described in the instructions) contains the component pantoprazole, which has the main therapeutic effect on the body. The amount of ingredient per 1 tablet can be 20 or 40 mg.

In the lyophilisate, 1 bottle also accounts for 40 mg of the active substance.

Tablet dosage form includes auxiliary ingredients:

  • Talc.
  • Macrogol.
  • Calcium stearate.
  • Mannitol.
  • Sodium carbonate.
  • Sorbitol.
  • Propylene glycol.

Excipients do not have medicinal properties. The lyophilisate also contains additional ingredients that do not have a therapeutic effect.

Pharmacological properties

The medicine belongs to proton pump inhibitors, therefore it has pronounced properties. The drug suppresses the production of hydrochloric acid, which in large quantities provokes damage to the mucous membrane of the digestive tract and leads to the development of diseases.

The product helps to protect the walls of the stomach and intestines from the negative effects of hydrochloric acid, prevents the progression of pathologies and the spread of lesions to large areas of the mucous membrane shell. As a result, the general condition improves.

The medication also has a beneficial effect on the production of digestive enzymes that facilitate digestion.

Pharmacodynamics and pharmacokinetics

The drug, when taken orally or parenterally, quickly affects the production of hydrochloric acid. It helps to reduce its amount, which prevents irritation of the walls of the stomach and intestines. As a result, digestion is facilitated and the likelihood of progression of the pathological process decreases.

The medicine normalizes the enzyme composition of gastric juice, despite a slight decrease in its amount during therapy.

Another effect of the medication on the patient's body is noted:

  • The pain, which often bothers patients with the progression of stomach pathologies, is eliminated. Discomfort is associated with irritation of the mucous membranes and the spread of the lesion over large areas.
  • The process of food processing is improved, especially in patients with digestive disorders.
  • In patients, the heaviness in the stomach area disappears after eating. Many talk about the elimination of heartburn, accompanying deviations from the digestive system.
  • The work of the pancreas and liver is facilitated. The functioning of these organs deteriorates in the presence of stomach pathologies, but with the use of the drug, an improvement is observed.
  • The functioning of the intestines is somewhat improved. Patients often suffer from diarrhea or persistent constipation.

After oral administration of the medication, improvement occurs in about 50-60 minutes. If the drug is administered parenterally, this time is somewhat reduced, but the effectiveness of therapy does not decrease. The drug is well tolerated by the body, processed in the digestive tract and relieves the condition quite quickly.

The processing of the ingredient is carried out in the liver, and the excretion of the components of the composition occurs with the help of the kidneys. Within 12-24 hours, the body is released from the decay products of the active component of the composition. If patients have liver or kidney pathologies, there is a slowdown in processing and excretion ingredients of the composition, which can slightly reduce the effectiveness and increase the concentration of the active substance in blood.

Chronic diseases of the digestive system often slow down the onset of the therapeutic effect if they are severe. This is due to impaired absorption of ingredients or an excessive increase in the concentration of components.

Indications for use

Nolpaza is used for various diseases of the digestive system.

The main indications for use:

  • Peptic ulcer of the stomach, duodenum, accompanied by severe symptoms and disorders of the digestive function.
  • Gastritis with increased acidity of gastric juice. At the same time, patients are worried about pain, heartburn, the process of food processing is disrupted, which leads to complications from the intestines.
  • Reflux disease, in which the patient often has dyspeptic disorders that worsen the general condition.
  • Diagnosis of gastritis, which occurs against the background of damage to the walls of the stomach by the bacterium Helicobacter pylori. The drug is prescribed in combination with other drugs to improve the effectiveness of treatment and prevent the development of complications.
  • Ulcerative and erosive damage to the walls of the stomach and intestines, which occurs against the background of a stressful state.

The drug is often prescribed as part of the complex treatment of pathologies of the liver, intestines, pancreas. The tool helps to enhance the effectiveness of treatment and prevents the progression of the disease.

Contraindications

An effective remedy has contraindications that should be considered before starting therapeutic use.

The main barriers to treatment are:

  • Identification of allergies to the components of the composition, a tendency to such manifestations in the patient's history. The remedy can provoke serious complications.
  • Diagnosis of insufficient production of hydrochloric acid and digestive enzymes. With the use of the drug, the suppression of these processes is noted, the patients develop complications.
  • The period of gestation and breastfeeding. Despite the absence of a teratogenic effect of the component on the development of the fetus, the drug can provoke complications, therefore its use at this time is not recommended.
  • Neurotic origin of dyspeptic disorders. The drug can be used to identify pathologies of the digestive tract against a background of stress, but some forms of the disease are not treated with this remedy.
  • Lack of liver or kidney function, in which the work of other organs worsens.
  • Malignant neoplasms of the digestive tract, which are characterized by rapid growth and complications.
  • Bowel obstruction in acute form, accompanied by severe symptoms and deterioration of the general condition of the patient.

In each case, there may be individual contraindications, since the drug has a different effect on the body. For elderly patients, the medicine is prescribed with caution, especially in the presence of chronic pathologies.

At what age can the drug be used?

Nolpaza (indications for the use of the drug are recommended to be taken immediately after the onset of symptoms of the disease) is prescribed only to adult patients.

This is due to the fact that today there is not enough data on the effect of the component of the composition on the body of patients under 18 years of age. In individual cases, use is possible, but according to strict indications and under the supervision of a specialist.

Instructions for use, dosage

Depending on the pathological condition and its severity, the drug therapy regimen may differ. The tablets are taken only orally in a certain dosage, the lyophilisate is intended for the preparation of a solution that is administered intravenously or with a dropper.

The treatment regimen is determined after examination and identification of the degree of neglect of the symptoms of pathology.

With gastritis

The dosage of the drug when diagnosing gastritis with increased acidity of gastric juice ranges from 20-40 mg per day. Usually, this norm is not exceeded, since it is enough to obtain a therapeutic result.

With gastritis, patients are very rarely prescribed a lyophilisate, since the tablets have the same properties and can be taken at home. Depending on the dosage in 1 tablet, you can take 1 or 2 tablets per day. Experts recommend dividing the norm into 2 doses during the day, which will ensure a uniform effect on the tissues of the digestive tract.

The duration of the therapeutic course depends on the severity of the manifestations. Sometimes 2 weeks are enough, often patients are extended the course up to 1 month. A prerequisite for taking pills is considered to be their use 30 minutes before meals. If a lyophilisate is used, 1 bottle is administered per day. The amount of active ingredient in it is 40 mg.

  • Before the introduction, the powder is dissolved in 20 ml of sodium chloride. 0,9%. This amount of solution is required for jet infusion.
  • If the patient receives the remedy with a dropper, 1 bottle of powder is taken for 100-200 ml of sodium chloride. The duration of therapy with the solution does not exceed 10 days.

In most cases, parenteral administration is required when the patient is in the hospital and in severe disease.

With pancreatitis

Nolpaza (indications for the use of the drug include not only disorders of the stomach and intestines) when diagnosed pancreatitis is prescribed as an auxiliary method of treatment, since patients often have complications from the work stomach.

In chronic subacute course, it is enough to take 20-40 mg of the drug per day in tablet form. The treatment lasts up to 3 weeks. If patients develop acute symptoms, hospitalization and administration of a parenteral agent are required.

The daily dosage usually does not exceed 40 mg, but sometimes it is increased to 80 mg when symptoms are acute. Most often, the drug is administered using a dropper, the powder is standardly diluted in 100 or 200 ml of sodium chloride. The treatment lasts up to 2 weeks, but in each case its duration is adjusted individually. In combination with the drug, other agents are prescribed, the action of which is directed directly at the therapy of the pancreas.

With VSD

Vegetovascular dystonia is not an indication for prescribing a medication, since the drug does not affect its course and does not help improve the condition. Despite this, many patients with chronic pathology can talk about frequent pain in the stomach, dyspeptic disorders.

During the examination, the doctor reveals gastritis against the background of damage to the autonomic nervous system. That is why, with an exacerbation of VSD, patients can be prescribed Nolpaza, but only in combination with other drugs. The dosage does not exceed 40 mg per day, which are taken from 10 to 20 days in a row.

In most cases, when prescribing, the doctor prefers the tablet dosage form.

Side effects

During the period of therapy, patients may experience negative reactions that worsen the condition. They affect not only the digestive system, but also the work of other organs.

Damage area Frequent negative reactions
Digestive tract On the part of the digestive system, disorders can manifest itself in the form of frequent loose stools and pain in the intestinal region. Sometimes there is severe flatulence, bloating, pain in the stomach. Patients report poor appetite and impaired digestive function. The symptomatology of the underlying disease is aggravated. Negative reactions disappear after discontinuation of treatment, but sometimes it is necessary to use other medications.
Nervous system Disorders from the nervous system do not occur so often, they usually manifest themselves against the background of other disorders. Weakness and fatigue are considered the most common reactions in patients. Sleep disturbance, irritability and decreased performance are sometimes noted. The drug has no effect on the functioning of the nervous system, does not lead to an aggravation of the manifestations of any chronic disorders.
Vessels and heart Complications from the heart and blood vessels occur in patients who have a history of chronic diseases of the cardiovascular system. Sometimes there is tachycardia, fluctuations in blood pressure indicators. Symptoms in most cases do not require special treatment.
Skin and mucous membranes Allergy to a medication manifests itself with classic symptoms in the form of a rash, burning sensation and itching. There is a spread of the rash to large areas of the skin, which leads to an aggravation of the manifestations. Patients comb the affected area, which significantly increases the risk of complications in the form of infection.

If complications appear, it is worth abandoning therapy with a remedy. If symptoms persist, it is recommended to see a doctor for specific treatment.

Overdose

Nolpaza (indications for use include pathologies accompanying upset stomach and intestine) does not lead to the development of an overdose if the patient follows all the recommendations and does not exceed dose.

With the simultaneous administration of an increased dose of the drug, it is possible to aggravate all negative reactions. Patients note not only allergic symptoms, but also acute systemic disorders. Overdose requires immediate discontinuation of therapy and the appointment of drugs to normalize the condition.

If the condition develops with the use of pills, gastric lavage is considered the first aid method, which allows you to get rid of the remnants of the pills.

special instructions

The drug is not used in the absence of indications. You can not take it for prophylaxis, independently increase the dose or prolong the therapeutic course.

When complications arise, do not ignore them. Aggravation of manifestations often leads to severe negative reactions, up to death, against the background of acute angioedema.

Drug interactions

Do not prescribe the remedy at the same time as antiviral drugs, as the condition may worsen and severe symptoms develop.

Experts also do not recommend taking it simultaneously with other drugs from the group of proton pump inhibitors. When combined with antibiotics, complications are not observed, but the choice of means is made by the doctor in each case individually.

Analogs

On drugstore shelves, you can find many substitutes with similar properties, they often contain the same ingredient in the composition.

The most effective of them:

  • Omeprazole contains an active ingredient of the same name, which has the same therapeutic properties. The drug helps to suppress the production of hydrochloric acid and reduce the risk of developing pathologies, as well as their progression. Like the original, the drug is available as a lyophilisate to make a solution. Oral capsules are also available. A substitute is often prescribed to patients when the original cannot be used. It is considered to be just as effective. The cost of an analogue is approximately 50-90 rubles.
  • Omez also considered a common substitute, contains omeprazole as the main active ingredient. The drug reduces the amount of hydrochloric acid in the stomach, which has a beneficial effect on the work of the entire digestive tract. An analogue can be found in the pharmacy in the form of tablets for oral use and a lyophilisate to obtain a solution. The remedy is prescribed in short and long courses, depending on the severity of the disease. The cost of the funds is 120-190 rubles.
  • Controlok has the same composition as the original medicine. The medicine is available in the form of tablets and powder for a solution that is administered parenterally. The tool has pronounced properties and improves the condition of patients when diagnosing pathologies of the stomach and intestines. The action of the substitute does not differ from the original, the drug is considered as effective. However, its cost is approximately 275-340 rubles.

The selection of a substitute is made only by a doctor, since they can provoke complications, despite the same therapeutic properties.

Terms, conditions of sale and storage

The drug is dispensed in pharmacies today upon presentation of a prescription from a doctor. Its storage period is 2 years.

Nolpaza. Instructions, indications for use, reviews
Nolpaza

After the expiration date, you should not use any dosage form. During storage, it is important to limit access to children and direct sunlight.

Price

The cost of the medication ranges from 230-520 rubles. depending on the number of tablets in the package.

Nolpaza is an effective pantoprazole-based drug that reduces the amount of hydrochloric acid in the stomach. The indications for its use are described in the instructions, which should be read before starting to use to prevent complications.

Video about the drug Nolpaza

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