Miscellaneous

Antibiotics for gastritis of the stomach with high, low acidity

click fraud protection

Content

  1. Why do you need antibiotics for gastritis?
  2. Contraindications to the use of antibiotics
  3. What groups of antibiotics are taken for gastritis
  4. Special instructions for admission, precautions for treatment
  5. Types of antibiotics and compatibility with other drugs, dosage regimens
  6. Amoxicillin
  7. Levofloxacin
  8. Azithromycin
  9. Tetracycline
  10. The choice of drugs by the type of acidity
  11. Antibiotic therapy regimens for various forms of gastritis
  12. Triple therapy and its essence
  13. Quadroscheme of antibiotic therapy for Helicobacter pylori infection
  14. How to enhance the effectiveness of antibiotic therapy?
  15. Side effects of taking antibiotics
  16. How to treat gastritis that developed after taking antibiotics
  17. How to eliminate dysbiosis with antibiotic therapy for gastritis
  18. Video about the treatment of gastritis

Antibiotics for acute or chronic gastritis of the stomach is prescribed as the main means of therapy to eliminate signs of the inflammatory process. Medicines in this category are used if the painful condition of the digestive organ was caused by bacterial microorganisms. The type of antibiotic is selected individually for each patient, depending on the strain of the pathogenic infection parasitizing on the walls of the stomach.

insta story viewer

Why do you need antibiotics for gastritis?

Antibiotics for bacterial inflammation of the stomach are necessary for the rapid suppression of pathogenic microflora, localization of the focus of the pathological process and prevention of complications. The lack of timely therapy for gastritis of an infectious etiology leads to the destruction of the mucous membrane of the digestive organ with the opening of the ulcerative process.

Antibiotics for gastritis of the stomach with high, low acidity
Antibiotics for gastritis of the stomach

Correctly selected antibiotics make it possible to completely destroy pathogenic microorganisms and normalize the function of the gastrointestinal tract with a minimum risk of recurrence of the disease.

Contraindications to the use of antibiotics

Each type of drugs from the pharmacological group of antibacterial agents has its own comprehensive list of contraindications.

There are general restrictions on the use of medicines in this category:

  • an allergic reaction to the main or auxiliary substances of the drug;
  • inflammation of the gastric mucosa is not bacterial in origin;
  • renal or hepatic impairment;
  • simultaneous administration of other medications is carried out, the constituent components of which are incompatible with antibiotics;
  • after the first use of the antibacterial agent, side effects or signs of individual intolerance to the drug have occurred;
  • being pregnant or breastfeeding a newborn.

Most antibiotics have age restrictions on their use. For example, some medicines are allowed for children aged 1, 3, 6 or 12 years old. Potent medicines with antibacterial properties are used to treat infectious gastritis of the stomach only in relation to adult patients.

What groups of antibiotics are taken for gastritis

Antibiotics for gastritis of the stomach are selected individually after microbiological examination of its mucous contents and tissue fragments.

In gastroenterology, antibacterial drugs of the following groups are most often used:

  • synthetic penicillins of a wide spectrum of action, the cleavage of which occurs under the action of penicillinase;
  • tetracycline series;
  • macrolides azalides;
  • fluoroquinolones.Antibiotics for gastritis of the stomach with high, low acidity

Antibacterial drugs of the above categories are effective against most gram-positive and gram-negative microorganisms. Medicines of these pharmacological groups have potent properties.

Special instructions for admission, precautions for treatment

Antibiotics for gastritis of the stomach are taken in continuous courses, the timing of which is determined by the gastroenterologist.

During therapy with medicines of this category, precautions must be taken:

  • Monitor the functional state of the liver, kidneys, and organs responsible for hematopoiesis.
  • Do not skip the next dose of the drug.
  • In the case of treatment with antibiotics containing tetracycline, it is forbidden to use dairy and fermented milk products. Otherwise, the drug will lose its effectiveness.
  • Stop antibacterial therapy if symptoms of an allergic reaction or other side effects appear.
  • Take an antibiotic in the dosage prescribed by the attending physician.
  • During therapy with antibacterial medicines, do not consume alcoholic beverages.
  • Refuse to drive vehicles and perform work with increased danger. Some types of antibiotics can cause side effects in the form of slowing down the reactions of the central nervous system.

The simultaneous administration of antibiotics from the macrolide group with ergotamine preparations can cause intoxication of the body. In this case, an additional load is created on the kidneys and liver tissue. Antibacterial drugs for the treatment of gastritis are prescribed with extreme caution to elderly patients. Patients in this category should be under constant supervision by medical personnel.

Types of antibiotics and compatibility with other drugs, dosage regimens

During the treatment of bacterial gastritis of the stomach, only one or several antibiotics are used at once. The anti-inflammatory therapy regimen is developed immediately after receiving the results of the gastrointestinal tract diagnostics.

Amoxicillin

Amoxicillin is a broad-spectrum antibacterial agent that belongs to the pharmacological group of synthetic penicillins. This medication is available in the form of white capsules with a red cap. The active ingredient of Amoxicillin is the chemical amoxicillin, but in the form of a trihydrate with a dosage of 500 mg.Antibiotics for gastritis of the stomach with high, low acidity

In terms of its pharmacological properties, this antibiotic is analogous to Ampicillin. The drug Amoxicillin exhibits a bactericidal effect, damaging strains of gram-positive aerobic microorganisms. Bacteria that synthesize the biochemical compound penicillinase are resistant to the active substance of this antibiotic.

For more effective treatment of infectious gastritis, Amoxicillin capsules are taken together with Metronidazole. This scheme of therapy allows you to eliminate inflammation of the stomach, which is caused by the bacterium Helicobacter pylori. The drugs Ampicillin and Amoxicillin are characterized by cross-resistance.

The antibacterial properties of this medication are enhanced by a beta-lactamase inhibitor of clavulanic acid compounds. After oral administration, Amoxicillin quickly dissolves in the gastrointestinal tract, but at the same time its main substance is not damaged by the acidity of gastric juice.

The table below shows the dosage regimen of Amoxicillin for children and adults.

Patient's age Dosage
Child 10 years old weighing no more than 40 kg The therapeutic dose is from 250 to 500 mg, and in a serious condition of the patient up to 1 g.
Children from 5 to 10 years old 250 mg
Child from 2 to 5 years old 125 mg
Children weighing less than 40 kg The dosage regimen is selected individually, but the average is from 20 to 100 mg of antibiotic per 1 kg of patient weight.
Patients over 18 years of age 250 mg to 1 g

The time interval between the next intake of Amoxicillin is at least 8 hours. During treatment with this medication with the simultaneous use of Metronidazole, the use of alcoholic beverages is contraindicated. Amoxicillin can reduce the effectiveness of oral contraceptives.

Parallel therapy with antibiotics of pharmacological groups causes the development of synergism:

  • aminoglycosides;
  • sulfonamides;
  • cephalosporins;
  • containing rifampicin.

Amoxicillin reduces the quality of assimilation of vitamin K, and also enhances the properties of indirect anticoagulants. Non-steroidal anti-inflammatory drugs, diuretic drugs and the substance phenylbutazone suppress the tubular secretion of the antibiotic Amoxicillin. The average cost of this antibiotic is 58 rubles. for 16 capsules.

Levofloxacin

Antibiotics for gastritis of the stomach are selected on an individual basis. Levofloxacin is a synthetic medication belonging to the category of fluoroquinolones, which is effective against most gram-negative and gram-positive microorganisms. The bactericidal properties of this antibiotic are realized by blocking DNA gyrase and damaging the cellular structure of pathogenic bacteria.

Antibiotics for gastritis of the stomach with high, low acidity
Levofloxacin 500 tablets

Reception of Levofloxacin is carried out at 500 mg 1 time per day with the duration of the course of therapy from 10 to 14 days. This antibiotic is contraindicated in patients under the age of 18, since there is a high probability of damage to the tissues of the intra-articular cartilage.

During the treatment of gastritis in elderly patients, it is necessary to monitor the condition of the kidneys. During the period of therapy with Levofloxacin, it is not recommended to expose open skin areas to prolonged exposure to sunlight. Throughout the entire course of treatment with this antibiotic, it is impossible to carry out the simultaneous administration of drugs that inhibit the motility of the gastrointestinal tract.

Patients who are deficient in glucose-6-phosphate dehydrogenase may experience a dangerous side effect of this medication in the form of hemolysis of the cellular structure of red blood cells. The therapeutic properties of Levofloxacin are significantly weakened in conditions of simultaneous administration of sucrafalt. A similar effect is observed when combining this antibiotic with antacids based on magnesium and aluminum. The average cost of Levofloxacin is from 245 rubles.

Azithromycin

Azithromycin is a synthetic macrolide-azalide antibiotic in capsule form with a dosage of 500 mg. This antibacterial drug is highly resistant to the acidic environment of gastric juice. Azithromycin is taken 500 mg once a day before or after a meal. Medicines from the antacid group do not significantly affect the bioavailability of the antibiotic, but reduce its concentration in the blood by 30%.

In this regard, Azithromycin is recommended to be taken 1 hour or 2 hours after a meal. In conditions of simultaneous therapy with antibiotics of the cyclosporin series, it is necessary to monitor the indicators of the biochemical composition of the blood. Treatment with Azithromycin and terfenadine-based drugs can cause arrhythmias. The average cost of this antibiotic is 55 rubles. for 6 capsules.

Tetracycline

Antibiotics for gastritis of the stomach can relieve the inflammatory process by suppressing the pathogenic activity of infectious microorganisms. Tetracycline is an antibacterial agent that comes in the form of tablets covered with a protective layer.Antibiotics for gastritis of the stomach with high, low acidity

The active substance of this medication is the chemical compound tetracycline hydrochloride at a dosage of 100 mg. An antibiotic of this category exhibits a bacteriostatic effect by stopping the synthesis of proteins formed between the ribosome and the bacterial RNA.

The dosage of tetracycline depends on the severity of the inflammatory process in the stomach. Children over 8 years of age take 20-25 mg / kg of this drug every 6 hours. For patients of the adult age group, the therapeutic dosage of tetracycline is from 300 mg to 1.5 g.

The duration of the therapeutic course is determined by the doctor. Throughout the entire period of gastritis treatment, it is necessary to monitor the functional state of the patient's kidneys. In case of manifestation of pathological symptoms from the organs of the excretory system, tetracycline therapy is discontinued, and the patient undergoes a comprehensive examination.

It is recommended to avoid the simultaneous administration of tetracycline with medications that contain metal ions. For example, antacids based on iron, calcium salts or magnesium compounds. Medicines of this category enter into a negative reaction with Tetracycline, forming chelates.

Antibiotics of the cephalosporin and penicillin series have bactericidal properties, disrupting the bacteriostatic effect of tetracycline. In this regard, these drugs are not used simultaneously. Therapy of gastritis with tetracycline with parallel administration of retinol is capable of provoking intracranial hypertension with a large number of complications.

Chymotrypsin increases the concentration of tetracycline in the patient's blood, and also slows down the process of its half-life with further excretion outside the body. The simultaneous administration of drugs based on colestipol and colestyramine interferes with the absorption of tetracycline into the intestinal wall. This leads to the fact that the antibiotic loses its therapeutic properties.

The suppression of the physiological activity of the intestinal microflora causes a decrease in the prothrombin index. Patients receiving concomitant treatment with indirect anticoagulants should reduce the dosage of these drugs. Otherwise, a blood clotting disorder is possible. The average cost of tetracycline is 60 rubles. for 1 plate of 20 tablets.

The choice of drugs by the type of acidity

In the process of treating gastritis of an infectious nature, antibacterial drugs are prescribed, the constituent components of which are resistant to the aggressive properties of gastric juice. Antibiotics for gastritis of the stomach with high, low acidityMedicines Amoxicillin, Tetracycline, Azithromycin do not disintegrate under conditions of high acidity. The choice of these medicines is carried out by the attending physician, depending on the strain of the bacterial microflora found inside the patient's stomach during the diagnosis.

Antibiotic therapy regimens for various forms of gastritis

Helicobacter pylori is the most common infectious organism that causes acute or chronic inflammation of the stomach walls. For the treatment of gastritis provoked by this bacterium, a therapeutic regimen of 3 or 4 antibiotics is used.

Triple therapy and its essence

Gastritis of bacterial etiology is very difficult to drug therapy, and there is always a risk of recurrence of the disease.

At the initial stage of treatment of this ailment, a more gentle drug regimen is used, consisting of 3 drugs of the following types:

  • Omeprazole - 2 times a day, 20 mg.
  • Amoxicillin - at a concentration of 500 mg up to 4 times a day, or this drug is prescribed for taking 1000 mg up to 2 times a day.
  • Clarithromycin - 500 mg 2 times a day. If necessary, this antibiotic can be replaced with drugs Josamycin or Nifuratel.Antibiotics for gastritis of the stomach with high, low acidity

At the discretion of the attending gastroenterologist, other antibiotics may be included in the triple therapy. For example, Tetracycline or Azithromycin, depending on the reaction of the patient's body to the use of drugs with antibacterial properties. The total duration of the course of treatment is from 10 to 14 days.

Quadroscheme of antibiotic therapy for Helicobacter pylori infection

The four-way treatment regimen includes the use of the following drugs to help get rid of infectious gastritis:

  • Omeprazole 20 mg 2 times a day.
  • Amoxicillin 500 mg 4 times a day or at a concentration of 1000 mg, but only 2 times a day.
  • Clarithromycin 500 mg up to 2 times a day.
  • Bismuth tripotassium dicitrate is prescribed at 120 mg taken 4 times a day.Antibiotics for gastritis of the stomach with high, low acidity

Medicines with antibacterial properties suppress the pathogenic activity of a bacterial infection, and bismuth-based preparation protects the inflamed stomach lining from irritating gastric juice. The duration of use of the antibiotic therapy quadrochem is 2 weeks.

How to enhance the effectiveness of antibiotic therapy?

During the treatment of infectious gastritis, it is necessary to use not only antibacterial drugs, but also drugs from the group of antacids, as well as proton pump inhibitors (PPIs). Medicines of these categories envelop the walls of the stomach, protecting them from the influence of gastric juice, and the synthesis of acid slows down.

The following proton pump inhibitors are recommended:

  • Omeprazole;
  • Sanpraz;
  • Gastrozole;
  • Nolpaza.

Any of the above drugs can be included in a triple or quadruple gastritis therapy regimen.

In combination with these medicines, the following antacids are used:

  • Phosphalugel;
  • Maalox;
  • Rennie;
  • Rutacid;
  • Almagel Neo.

During treatment with auxiliary drugs in the form of antacids, special attention should be paid on the nature of the drug interaction of these medicines with antibiotics that are prescribed a doctor.

Side effects of taking antibiotics

Therapy with antibacterial drugs can be accompanied by the following side effects:

  • nausea;Antibiotics for gastritis of the stomach with high, low acidity
  • complete or partial loss of appetite;
  • discharge of vomit;
  • dizziness;
  • the appearance of a red rash on the surface of the skin;
  • hives;
  • attacks of severe headache;
  • discomfort in the stomach and intestines;
  • diarrhea;
  • yellowing or darkening of tooth enamel;
  • anaphylactic shock;
  • conjunctivitis of an allergic nature of origin;
  • a state of chills and fever;
  • peripheral neuropathy;
  • lack of clarity of consciousness;
  • cramps of the lower extremities;
  • impaired renal and liver function;
  • colitis;
  • cholestatic jaundice;
  • constipation;
  • inflammation of the liver tissue;
  • anorexia;
  • exfoliative dermatitis.

If the first signs of side effects appear, you must immediately stop taking further antibiotics and then seek medical attention from your gastroenterologist or therapist.

How to treat gastritis that developed after taking antibiotics

Inflammation of the walls of the stomach, which has arisen after prolonged antibiotic therapy, can be caused by a local allergic reaction to the constituent substances of these medicines.

To restore the normal state of the gastrointestinal tract, the following groups of drugs with anti-inflammatory, healing and antihistamine properties are used:

  • antacids;Antibiotics for gastritis of the stomach with high, low acidity
  • bismuth preparations;
  • antiallergic agents (Suprastin, L-Cet, Aleron, Tavegil).

The selection of medicines and the setting of the dosage regimen is carried out by the attending physician after examining the patient's stomach with an accurate determination of the reasons that caused its inflammation.

How to eliminate dysbiosis with antibiotic therapy for gastritis

Long-term treatment of gastritis with antibiotics periodically causes a side effect in the form of intestinal dysbiosis.

To get rid of this ailment, the following remedies from the probiotic group are used:

  • Linex;
  • Symbiolact Plus;
  • Lactobacterin;
  • Florin Forte;
  • Enterol;
  • Bifiform.

The above preparations contain live bacterial cultures that restore the normal balance of the intestinal microflora. The duration of treatment with probiotics and the dosage are selected individually depending on the condition of the patient's gastrointestinal tract, but the average duration of therapy is from 2 weeks to 1 month.

Gastritis of the stomach caused by infectious microorganisms is a serious and dangerous disease that accompanied by bouts of severe abdominal pain, loss of appetite, general digestive upset systems.

Treatment of this pathology requires an integrated approach using broad-spectrum antibiotics, antacids, bismuth preparations. With gastritis of bacterial etiology, antibacterial medicines are prescribed in the form of Azithromycin, Metronidazole, Tetracycline. The average duration of a therapeutic course is 10-14 days.

Video about the treatment of gastritis

How to properly treat gastritis:

  • Share
The nerve is in the tooth. Where is located, photo, inflammation, removal
Miscellaneous

The nerve is in the tooth. Where is located, photo, inflammation, removal

ContentWhat is a dental nerve and what does it look likeWhere is located, structure, functionsCauses of nerve inflammationSigns of inflammationWhen...

State Register of Medicines 2021 VED. What is it, how to use, site
Miscellaneous

State Register of Medicines 2021 VED. What is it, how to use, site

ContentWhat it isData registry creation historyWhat information doesWhy and for whom is it intendedHow to useWhat is VEDVideo about the state regis...

Conditionally removable prosthesis on implants. Price for the upper, lower jaw, reviews
Miscellaneous

Conditionally removable prosthesis on implants. Price for the upper, lower jaw, reviews

ContentWho is it suitable for, what teeth is it used forDesignLife timeTypes of prosthesesInstallation technology1st stageStage 2Stage 3PriceContra...