Content
- Release form
- Chemical composition
- Pharmacological properties
- Pharmacodynamics and pharmacokinetics
- Indications for use
- Contraindications
- At what age can the drug be used?
- Instructions for use, dosage
- Thrombotic ACC 50 mg
- Thrombotic ACC 100 mg
- Side effects
- Overdose
- special instructions
- Drug interactions
- Analogs
- Acetylsalicylic acid
- Acecardol
- Sanovask
- Terms, conditions of sale and storage
- Price
- Video about the drug Thrombo ACC
Thrombotic ACC is a drug, used in the treatment of various diseases of an inflammatory origin. The drug has an acceptable cost, depending on the dispensed dosage - 50 or 100 mg of the active substance.
Release form
The medicine is manufactured in Russia in the form of enteric tablets.
Description: capsules are white, round.
The product is contained in plastic blisters packed in cardboard boxes.
Chemical composition
The active ingredient is acetylsalicylic acid.
Additional composition:
- milk sugar;
- MCC;
- potato starch;
- talc;
- food additive E1518;
- eudragitis L;
- colloidal silicon dioxide.
Thanks to the complex action of all ingredients, a therapeutic effect is achieved.
Pharmacological properties
The drug belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and has a pronounced analgesic and antipyretic effect. The action of the drug is aimed at inhibiting the activity of COX-1, which leads to the suppression of the production of mediators of pain and inflammation, thromboxane and highly active metabolites of arachidonic acid.
The active substance prevents the development of blood clots, which is due to its ability to prevent platelets from sticking together. It also has an antiplatelet effect that lasts for a week after oral use.
Pharmacodynamics and pharmacokinetics
The components of the drug are rapidly and almost completely absorbed from the gastrointestinal tract, partially undergoing metabolic transformation. When ingested, the drug is metabolized in the liver and breaks down into several different metabolites, most of which are found in urine. In women, the reaction of converting the active component into metabolites takes longer.
The main ingredient interacts with proteins. The level of binding in this case varies from 66 to 98%. The components of the drug are able to penetrate the placental barrier and enter breast milk. The half-life of the active substance is 15-20 minutes. However, it does not have a cumulative effect. The drug leaves the body mainly by the renal system. The elimination process takes from 1 to 3 days.
Indications for use
Thrombotic ACC 100 mg (the price of tablets of different dosages may differ) and 50 mg have absolutely identical recommendations for the appointment. The medication has a wide range of applications and is prescribed for conditions associated with the development of inflammation and pain.
Indications:
- prevention of the development of myocardial infarction (in the presence of risks or predisposition), including repeated episodes of the violation;
- angina pectoris (stable or unstable form of the disorder);
- stroke (as a preventive treatment);
- circulatory disorders in the brain (prevention of the development of the disease);
- thromboembolic syndrome (prophylactic use after vascular surgery);
- the formation of blood clots in the area of deep veins or in the pulmonary artery (as a preventive therapy).
The tablets should be used only after a diagnosis has been made and confirmed.
Contraindications
The drug has some limitations, in the presence of which you should refuse to take it, since this can complicate existing diseases or lead to the development of additional complications.
Contraindications:
- intolerance to the components;
- children under the age of 18;
- pregnancy (1st and 3rd trimester);
- lactation period;
- bronchial asthma, occurring together with polyposis (with intolerance to the main component of the drug);
- bleeding, formation in the gastrointestinal tract;
- the presence of ulcers and erosions in the gastrointestinal tract;
- chronic heart failure;
- failure of the kidneys and liver;
- lack of lactase, allergy to lactose, glucose-galactose malabsorption syndrome;
- diathesis (hemorrhagic type of disorder);
- bronchial asthma caused by taking aspirin or other drugs that have an identical composition.
In these conditions, it is recommended to choose another drug.
Take pills with extreme caution in the following cases:
- gout;
- an increase in the level of uric acid in the blood;
- the presence of ulcers and bleeding in the stomach;
- hay fever;
- failure of the kidneys and liver (moderate forms);
- polyps in the nose;
- bronchial asthma;
- damage to the respiratory organs (chronic forms);
- allergy to drugs with a similar composition;
- period before operations;
- 2nd trimester of pregnancy;
- concomitant use with certain drugs.
In these conditions, therapy is carried out under the supervision of a physician.
At what age can the drug be used?
The medicine is prohibited for use in childhood and adolescence. It can be prescribed from the age of 18.
Instructions for use, dosage
The capsules are intended for oral use. They are taken before meals, washed down with 1 tbsp. water. The duration of treatment is determined individually and can be several months.
Thrombotic ACC 50 mg
In a dosage of 50 mg, take 1 capsule 1-2 times a day.
As a prophylaxis for the formation of blood clots in the deep veins and pulmonary artery, use 2-4 tablets per day.
Thrombotic ACC 100 mg
In a dosage of 100 mg, take 1 capsule per day. When preventing the development of blood clots in the deep veins and pulmonary artery, the dose can be increased to 2 tablets per day.
Side effects
Thrombotic ACC 50 mg (the price of the drug is affordable for most patients) leads to the development of negative effects in rarer cases than the drug with higher dosages.
Adverse reactions occur extremely rarely and are associated with the individual characteristics of the patient's body and the influence of active components.
Side effects:
- Digestive organs: signs of dyspepsia, abdominal pain. In more rare cases, ulcers and bleeding in the gastrointestinal tract may occur, as well as an increase in the activity of liver enzymes.
- CNS: hearing impairment, tinnitus, the development of dizziness.
- Hematopoietic function: bleeding (including from the nose, gums or genitals), bruising. There were also recorded cases of bleeding in the gastrointestinal tract and cerebral hemorrhages. At the same time, the development of anemic conditions with concomitant symptoms was noted.
- Allergy Signs: rashes on the skin, itchy elements, urticaria, Quincke's edema. In some cases, there were swelling of the mucous membranes, signs of rhinitis, spasms in the region of the bronchi. Distressful states and anaphylactic reactions occasionally occurred.
In the event of the development of these signs, as well as other symptoms not noted in the instructions, it is recommended to stop further taking the pills and seek medical advice.
Overdose
If the dosages prescribed by a specialist are exceeded, a negative effect may develop, especially in the elderly and children.
Overdose:
- noise in ears;
- dizziness;
- hyperhidrosis;
- migraine;
- nausea and vomiting;
- violation of consciousness;
- apnea;
- increased work of the lungs;
- compensated form of alcoholosis;
- suffocation;
- depression of respiratory function;
- excessive fever;
- disruption of the heart;
- dehydration;
- decrease or increase in glucose levels;
- ketoacidosis;
- dysfunction of blood clotting;
- the formation of bleeding in the gastrointestinal tract;
- oppression of the central nervous system;
- toxic brain damage.
With the development of such symptoms, further use of the medication should be canceled and a doctor should be consulted for symptomatic therapy. Treatment: intake of sorbents, forced diuresis, extrahepatic blood purification, restoration of pH and water-electrolyte balance.
special instructions
Thrombotic ACC should be used with extreme caution in elderly patients and children. In this case, this category of patients is recommended to prescribe lower dosages of the drug (50 mg).
To undergo a full course of therapy, it is recommended to purchase several packs of tablets at once. The cost of the drug is affordable and quite acceptable for most buyers.
The medicine can provoke the development of various allergic reactions, especially in patients with hypersensitivity to the components.
After taking the drug, the risks of bleeding before or after surgery increase, therefore, if necessary, you should stop taking the pills before the operation.
The medication can lead to gout, especially in patients with a predisposition to this disorder. Extremely careful use in this category of patients is required. Drug therapy in patients with diabetes mellitus and taking hypoglycemic agents should be carried out with extreme caution and only under the supervision of a specialist. Reception of increased dosages of the drug can lead to the development of bleeding in the gastrointestinal tract, which must be taken into account in the elderly.
In some cases, the drug can lead to the development of dizziness, and therefore, it is necessary to refuse or take great care when driving a car or carrying out other work that requires the speed of psychomotor reactions.
Drug interactions
The drug can react with other medicines.
At the same time, various negative effects develop:
- Methotrexate is an enhanced action of the drug.
- Anticoagulants and antiplatelet agents, thrombolytics - an increase in the risk of bleeding; damage to the gastrointestinal mucosa.
- Selective serotonin reuptake inhibitors - increase the risk of bleeding in the gastrointestinal tract.
- Digoxin - an increase in the concentration of drug components.
- Hypoglycemic drugs and insulin - an increase in the effect of medications.
- Valproic acid - an increase in the toxic effects of this drug.
- NSAIDs - platelet suppression, increased risk of bleeding in the gastrointestinal tract.
A decrease in the effect of the main drug can occur when it is used simultaneously with the following drugs:
- Diuretics
- ACE inhibitors.
- Uricosuric preparations.
- Systemic glucocorticosteroids.
When using other drugs during the period of prescribing tablets, you should inform the treating person about this in advance. doctor, which will avoid drug incompatibility and, as a result, prevent the development of negative reactions.
Analogs
Thrombotic ACC 100 mg (the price of tablets is not a reason for replacing them) in some cases can lead to the development of intolerance reactions. In the event of such manifestations, it is recommended to replace the medication with another drug that is similar in indications and action.
The selection of generics should be carried out by the attending physician, taking into account the severity of the course of the disease, the condition and other physiological characteristics of the patient.
It is not recommended to prescribe and use substitutes on your own, since an incorrectly selected drug can worsen the condition and cause the development of additional complications.
Acetylsalicylic acid
This product is manufactured in Russia in the form of enteric tablets, the active ingredient of which is acetylsalicylic acid.
The drug belongs to the class of non-steroidal anti-inflammatory drugs and has analgesic and antipyretic effects.
Recommendations for the appointment:
- pain in the chest area;
- myocardial infarction (as a prophylaxis);
- ischemic strokes and attacks, including repeated episodes (for patients who have recently suffered from cerebrovascular accidents);
- prevention of the development of thrombosis after previous surgical operations.
- Dosing regimen: one-time rates - from 40 mg to 1 g, daily dosages - from 0.15 to 8 g.
- The duration of treatment is individual, according to the recommendations of a specialist.
- The drug has multiple contraindications and restrictions on admission, so you should familiarize yourself with them in advance.
- Age restrictions - for adults and children over 15 years old.
- The tablets are prohibited from taking during breastfeeding, as well as in the 1st and 3rd trimesters of pregnancy.
- Terms of sale - over the counter.
- The price of a medicine in public and private pharmacies in Russia ranges from 3 to 65 rubles.
Acecardol
This substitute is produced by a domestic manufacturer of drugs in the form of tablets for oral use.
The active ingredient is acetylsalicylic acid.
Application area:
- myocardial infarction (primary or re-development of the disease) - as a prophylaxis;
- prevention of thrombus formation in veins, vessels and arteries;
- thromboembolism due to vascular surgery (prevention);
- stroke (ischemic disorder);
- unstable form of angina pectoris.
- Dosing rules: 0.1-0.3 g 1 time per day, every day or every other day. The duration of therapy is individual (long-term), according to the doctor's recommendations.
- The tool has a huge list of contraindications that you should familiarize yourself with in advance.
- Age restrictions - for adults and children over 18 years old.
- The drug is prohibited for use with breastfeeding, as well as in the 1st and 3rd trimesters of pregnancy.
- Vacation conditions - over-the-counter.
- The cost of the drug in regional and regional pharmacies in Russia varies from 20 to 30 rubles.
Sanovask
Thrombotic ACC 50 mg (the price of similar drugs may differ significantly from the cost of the original product) and 100 mg can be replaced by such a popular and effective medicine as Sanovask. This generic is produced in Russia in the form of enteric tablets. The active ingredient is acetylsalicylic acid. The medication has a pronounced anti-inflammatory and analgesic effect.
Indications for admission:
- prevention of ischemic stroke or ischemic attacks (for patients who have recently suffered from circulatory disorders in the brain);
- angina pectoris (stable and unstable course of pathology);
- prevention of blood clots after previous surgical actions on the vessels.
- Dosage regimen: from 40 mg to 1 g (one time). Daily norms - from 0.15 to 8 g. The number of applications per day varies from 2 to 6 times.
- Duration of treatment - according to the doctor's recommendations according to the identified violation.
- The drug has multiple contraindications, including the 1st and 3rd trimester of pregnancy, as well as children under 15 years of age.
- The tablets can be used only in the 2nd trimester and only under the supervision of a treating specialist.
- The way of implementation is over-the-counter.
- The cost of a medicine in commercial and state pharmacies in Russia starts from 35 rubles.
Terms, conditions of sale and storage
- The medicine should be stored in a dark and dry place at temperatures up to 25 0C.
- Shelf life is 3 years from the date of issue.
- Do not use after the expiration date stated on the package.
- Dispensing method - over-the-counter.
Price
The prices for the drug may vary slightly depending on the region of sale and the pharmacy trade network.
Region / region | Dosage form / dosage | Price |
Moscow, Moscow region | Tablets, 100 mg | RUB 30-185 |
St. Petersburg | Tablets, 50 mg | 35-160 rub. |
Saint Petersburg (suburbs) | Tablets, 100 mg | 35-165 rub. |
Leningrad region | Tablets, 100 mg | 40-120 rubles |
Novgorod region | Tablets, 50 mg | RUB 45-95 |
Before using Thrombo ACC, you should consult with a specialist and carefully study the instructions for the use of tablets, especially attention should be paid to taking the drug with different dosages of the active substance (50 or 100 mg). You can clarify the cost and purchase the medicine at any pharmacy located in your place of residence.
Video about the drug Thrombo ACC
Is it always necessary to take Thrombo ACC: