Tivortin (Tivortin) analogues in Russia by active ingredient

Tivortin is a drug that also has a second international name Arginine. This medication is available in the form of a liquid solution for intravenous infusion with an active ingredient concentration of 4.2% per 100 ml of the finished product. The active component of this drug is the chemical compound arginine hydrochloride, and sterile water for injection performs an auxiliary function.

Tivortin belongs to the pharmacological group of amino acids with plasma-substituting and nutritional properties. This medication is used to treat severe cardiovascular diseases.

Tivortin is produced by the Ukrainian pharmaceutical company Yuria-Pharm LLC. A large number of drugs with similar properties are sold in Russian pharmacies.

Domestic and imported analogues of the product

Tivortin is a powerful prescription medication. Domestic and imported analogues of this medication can be purchased in most cities of Russia, but only after the preliminary prescription of the medication by a doctor.

Dipeptive

Dipeptiven is a drug produced by the Austrian pharmaceutical company Fresenius Kabi.

This medication and the infusion agent Tivortin have the following pharmacological similarities:

• both drugs are designed for intravenous administration in the form of a drop solution;

  

• the constituent components of Dipeptiven and Tivortin are amino acids that are necessary for the human body for full functioning and further development;
• medicines of these types accelerate the process of tissue regeneration, restoration of internal organs and life support systems after serious illnesses, the consequences of surgical intervention and injuries;
• drugs Dipeptiven and Tivortin belong to a single pharmacological group of drugs for parenteral nutrition;
• course reception of these medicines allows you to increase the protective functions of the immune system, eliminate the signs of immunodeficiency states;
• both drugs are intended for infusion therapy with their infusion into the central venous cavity;
• the drugs Dipeptiven and Tivortin can cause the same side effects in the form of a local or extensive allergic reaction, nausea and vomiting;
• these medicines can be used as part of a combination therapy with the simultaneous use of other medicines aimed at a faster recovery of the patient's body.

Despite the fact that Dipeptiven and Tivortin have a similar effect on the internal organs of a person, these drugs have a large number of differences, which consist in the following characteristics:

• the drug Dipeptiven contains several completely different amino acids at once in the form of L-alanine and L-glutamine, and arginine is also completely absent;
• the drug Dipeptiven is produced in the form of a concentrate for further preparation infusion solution with an active ingredient of 20%, and Tivortin is initially produced in the form intravenous infusion;
• the drug Dipeptiven can be used to treat not only adults, but also patients of the pediatric age category, and the Tivortin solution is approved for use only in relation to patients over 18 years old;
• the medication Tivortin is prescribed to pregnant women to eliminate pathological signs of delay in the physical development of the fetus, and the amino acid complex Dipeptiven is contraindicated for use for the treatment of patients with this categories;
• Tivortin infusion solution can be purchased at most city pharmacies on the basis of a prescription from the attending physician, and Dipeptiven is dispensed only at health care facilities.

Tivortin (analogues in Russia have different costs) can be prescribed by the attending physician for joint use with the drug Dipeptiven. For example, if the patient is in serious condition, requires a regular intake of the amino acids L-glutamine and L-alanine, and also needs arginine therapy.

Betargin

Betargin has similar therapeutic effects as the drug Tivortin.

The drugs have similarities in pharmacological characteristics:

• both products contain the biologically active substance arginine;
• Betargin and Tivortin have the same form of release in the form of a liquid transparent solution without signs of a specific odor;
• these drugs are used as the main and auxiliary means to maintain the vitality of the body, increase the efficiency of the liver and other internal organs;
• both amino acid solutions are equally contraindicated in patients under 18 years of age;
• the constituent substances of Betargin and Tivortin stimulate metabolic processes in the body, improving the biological synthesis of phospholipids;
• both drugs are not used as a means of symptomatic therapy, but are intended to be taken during a continuous course of treatment;
• in terms of chemical properties, Betargin and Tivortin are vital amino acids necessary for the normal functioning of the body;
• the drugs Betargin and Tivortin have a beneficial effect on the functions of the gastrointestinal tract, contributing to its rapid recovery from previous inflammatory diseases.

The drug and Tivortin and Betargin solution have not only pharmacological similarities in terms of similar effects on the human body, but also a number of the following distinctive features:

• the source of amino acids Betargin is not a medicine, but is produced under the brand name of a dietary supplement, which is included in the main diet;
• the drug Betargin is distinguished by an expanded biochemical composition, since it contains an additional substance betaine;
• therapeutic agent Betargin is produced in the form of a liquid transparent solution, which is taken orally in the form of a drinking suspension, and the medication Tivortin is indicated for intravenous infusion;
• the drug Betargin is not used to treat women in a state of pregnancy, and the intravenous solution of Tivortin does not have such restrictions on use;
• Betargin liquid solution is contraindicated for the treatment of patients diagnosed with disorders carbohydrate metabolism, and the medication Tivortin can be used in the presence of similar problems with health;
• Betargin is available in the form of glass ampoules or sticks, which contain a single dose of this agent to be taken orally;
• the drug Betargin cannot be used as the main therapeutic agent, since it acts as an additional component in the general diet;
• to purchase dietary supplements Betargin does not require a prescription from the attending physician;
• the drug Tivortin is characterized by a large therapeutic effect, as well as a rapid saturation of the body with the required amount of arginine (this distinctive feature the drug is due to the fact that the amino acid enters the patient's body directly into the venous bloodstream through a dropper, and part of the taken Betargin goes through the stage of chemical decomposition in organs of the digestive tract).

The dietary supplement Betargin is produced by the Russian pharmaceutical company Pharma International LLC. This tool cannot be classified as analogue drugs that can completely replace the Tivortin infusion solution. These drugs are not interchangeable.

L-Arginine hydrochloride

Arginine and the drug Tivortin have the following pharmacological similarities in terms of their effects on the human body:

• increase the efficiency of internal organs and life support systems;
• prevent the development of atherosclerosis of peripheral blood vessels, which reduces the likelihood of sudden onset of myocardial infarction and ischemic stroke of the brain;
• both drugs are a source of the vital amino acid arginine;
• regular intake of drugs L-Arginine and Tivortin has a beneficial effect on the functions of the digestive tract;
• the constituent components of these funds contribute to a faster regeneration of muscle tissues after physical exertion, as well as during post-traumatic and postoperative rehabilitation;
• drugs L-Arginine and Tivortin normalize blood pressure indicators;
• the active substance arginine hydrochloride, contained in the composition of these therapeutic agents, stimulates the process of spermatogenesis in men, and also increases the quality characteristics of sperm;
• regular use of these drugs provides high-quality nutrition for muscle tissue and all parts of the musculoskeletal system;
• both therapeutic agents are equally contraindicated in women who breast-feed a newborn baby;
• drugs L-Arginine and Tivortin can cause attacks of allergic reactions in patients with individual intolerance to arginine and other substances based on this amino acid;
• these funds are included in the complex therapy of cardiovascular diseases and pathological conditions organism associated with its depletion or the period of rehabilitation after severe injuries, previously underwent surgical operations.

Tivortin (analogs in Russia are sold without a doctor's prescription, if it is a biologically active food supplement) and the drug L-Arginine have not only a number of pharmacological similarities, but also significant differences, consisting in the following characteristics:

• the therapeutic agent L-Arginine is available in the form of gelatin capsules intended for oral administration, which must be washed down with a sufficient amount of water;
• the drug L-Arginine is contraindicated for use in women who are in a state of pregnancy, and infusion Tivortin solution is used by doctors to stimulate the physical development of the fetus, which is lagging behind the timing of recruitment weight;
• L-Arginine capsules are not a medicine, but are registered by their manufacturer as a dietary supplement to the main diet;
• the drug Tivortin can cause signs of phlebitis in the area of ​​infusion solution, and the use of the drug L-Arginine is not the cause of such health problems;
• the use of the drug Tivortin is contraindicated in men and women who have severe kidney pathologies, as well as carry out concomitant therapy with medicines from the group of potassium-sparing diuretics, dietary supplement L-Arginine has no similar restrictions;
• infusion therapy with intravenous Tivortin solution can lead to the development of hyperkalemia, and treatment with L-Arginine capsules does not cause similar effects;
• the introduction of the drug Tivortin is dosed at intervals of intravenous infusion of 2, 3, 5, 7 or 10 days in depending on the type of the diagnosed disease, and the dietary supplement L-Arginine is taken 3 capsules daily directly during meals;
• the dosage of the drug L-Arginine is 500 mg of pure arginine in 1 capsule, and the medicinal Tivortin solution has a concentration of the active ingredient in the form of arginine hydrochloride 4.2 g per 100 ml medication;
• the maximum concentration of Tivortin in human blood plasma is reached after 20-30 minutes. from the start of infusion therapy, and in the case of taking capsules, a similar effect is observed no earlier than 1-2 hours (this is when provided that the patient does not have concomitant pathologies that disrupt the natural process of absorption of arginine into the walls Gastrointestinal tract);
• solution for intravenous administration Tivortin is able to overcome the placental barrier, penetrating into the tissues of the developing fetus, and L-Arginine capsules do not have similar properties;
• filtration of the drug Tivortin occurs in the structure of the renal glomeruli, and in the case of therapy with L-Arginine, the main burden of its metabolic breakdown falls on the liver tissue.

The advantage of the drug Tivortin over the drug L-Arginine is that it has an increased therapeutic efficacy, and its active the substance in the form of a vital amino acid is delivered directly into the general bloodstream, bypassing the preliminary stages of metabolic decay in the digestive tract and liver.

The dietary supplement L-Arginine cannot be used as an independent agent for the treatment of severe diseases of internal organs and life support systems of the body.

Vazoton

Tivortin (analogues in Russia are produced in the form of liquid solutions and cylindrical capsules) and Vasoton have the following pharmacological similarities:

• both therapeutic agents contain the same active ingredient in the form of arginine;
• the active component of these drugs is an amino acid, which is necessary for the human the body to maintain stable functions of internal organs, skeletal muscles and systems life support;
• infusion solution Tivortin and the drug Vasoton act as a safe regulator of metabolic processes that occur at the intracellular level;
• the amino acid contained in these therapeutic agents has a hepatoprotective effect, increasing the functional the capabilities of the liver (this pharmacological property of drugs is realized provided that a person does not have severe pathologies of this body);
• taking Vasoton regularly and receiving intravenous doses of Tivortin ensures that antihypoxic effect, and also stabilizes the membrane structure of muscle tissue cells and internal organs;
• the constituent substance of these drugs protects the body from the harmful effects of free radicals, and also exhibits pharmacological properties that are similar to antioxidants;
• Vasoton and Tivortin maintain a stable balance of female and male sex hormones, preserving the health of the whole organism;
• Dosed use of these therapeutic agents leads to an increase in the level of insulin in the blood plasma, and also contributes to an increase in indicators growth hormone, prolactin and glucagon (these properties of amino acid preparations are equally useful to all people who have concomitant diseases of the endocrine systems);
• Vasoton and Tivortin similarly affect the physiological processes of fibrinolysis, accelerating the rate of regeneration epithelial and muscle tissues damaged as a result of injury, serious illness or previous surgical operations;
• the constituent substance of these drugs stimulates the organs of the male reproductive system to synthesize more germ cells, and also increases the quality of sperm;
• both therapeutic agents are directly involved in the biochemical conversion of ammonia to urea;
• arginine contained in these preparations is a chemical substrate for catalyzing the synthesis of an additional amount of nitric oxide in the structure of endotheliocytes;
• the action of these funds is aimed at preventing the formation of atherosclerotic plaques in large arterial vessels;
• Vasoton and Tivortin infusion solution improve the functions of the thymus gland, which is responsible for the synthesis of blood T-cells;
• these drugs regulate the balance of glucose in the blood at the time of intense physical work and sports;
• therapeutic agents of these types have an acid-forming effect, helping to restore the optimal ratio of acid and alkaline substances present in the human body.

The drugs Vasoton and Tivortin have not only a large number of pharmacological similarities, but also the following differences:

• the therapeutic agent Vasoton is available in the form of capsules with a concentration of the active substance arginine of 180 and 500 mg;
• Vasoton is a dietary supplement to the main diet and does not belong to the category of medicines;
• Vasoton is contraindicated in women who are in a state of pregnancy, and Tivortin is prescribed to these patients if a lag in the physical development of the fetus is detected;
• the drug Vasoton is taken orally with its further dissolution in the gastrointestinal tract, and Tivortin enters the patient's body in the form of an intravenous infusion, the dosage regimen of which depends on the variety diseases.

Tivortin (analogues in Russia are presented not only in the form of medicines, but also in the form of dietary supplements) may cause a mild sensation of heat, headache, which occur soon after injection drug.

Prices

The average cost of the drug Tivortin is 365 rubles. The table below lists the approximate prices for drugs analogs of this medication.

Name of the medicine	Cost in pharmacies
Dipeptive	From 20,000 to 23,000 rubles. per bottle 100 ml
Betargin	From 4450 to 4680 rub. per pack of 20 ampoules of 10 ml
L-Arginine	From 1171 rub. for 1 bottle containing 50 capsules
Vazoton	From 183 to 190 rubles. for 30 capsules

Tivortin is a drug designed for intravenous infusion therapy in adult patients. age group with atherosclerosis of blood vessels, pulmonary hypertension, angina pectoris and coronary heart disease muscles. This medication has a pharmacological advantage over other analog drugs sold in Russia.

It consists in the fact that Tivortin can be used to treat pregnant women with a delay in the physical development of the fetus, as well as signs of preeclampsia. This drug is taken only intravenously by installing a dropper. The dosage regimen and duration of treatment with Tivortin depends on the type of disease diagnosed.

Video about the analogue of Tivortin

Solution Betargin description and instructions: