Lizobact during pregnancy 1-2-3 trimester

Lizobact is an effective drug, which belongs to the pharmacological group of local antiseptics. This medication was created for the complex treatment of dental diseases and pathological conditions of the ENT organs. Lizobakt is produced by the Bosnian pharmaceutical company AO Bosnalék.

The active substances of this drug are approved for use by women who are in a state of pregnancy. In this case, the term of fetal development does not matter (can be taken during 1-2-3 trimesters). Lizobact is used as an independent means of therapy, and is also included in the general course of treatment of bacterial and inflammatory diseases.

Indications for use

The drug Lizobact is not intended for symptomatic therapy. This medication is taken in continuous courses, the duration of which is determined by the dentist or otolaryngologist.

The drug Lizobact has the following pharmacological properties:

• destroys gram-positive and gram-negative microorganisms;
• promotes more accelerated regeneration of the oral mucosa, which has been damaged as a result of an infectious process;
• increases the protective functions of the local immunity of the larynx and nasopharynx (this property of Lizobact is especially useful for people who suffer from tonsillitis and other chronic throat diseases);
• relieves inflammation and swelling of the mucous membrane;
• shows the same therapeutic efficacy in the treatment of diseases of the oral cavity and larynx, which are caused by bacterial, viral, and fungal infections;
• enhances the therapeutic effect of antibacterial drugs.

The antiseptic properties of Lizobact allow you to get rid of an unpleasant odor from the oral cavity, which is caused by an inflammatory process of an infectious nature of origin. This medication is equally effective for diseases of the nasopharyngeal mucosa and pathological conditions of the gums.

The drug Lizobact is indicated for use in the following clinical cases:

• ulceration of the mucous membrane of the aphthous type;
• complications of herpes infection, when papular blisters affect the mouth and throat;
• inflammation of the gums;
• stomatitis of viral, bacterial or fungal etiology;
• erosive processes inside the oral cavity;
• diseases of the upper respiratory tract, accompanied by inflammation, dry cough, sore throat, hoarseness.

Lizobact is one of the few medications that are allowed for women in the 1st and 2nd trimester of pregnancy. The absence of therapeutic restrictions allows the use of this medication in the treatment of acute and chronic infectious processes in patients of this category.

For example, if, due to hormonal imbalance and weakening of general immunity, a woman falls ill with stomatitis, gingivitis or pharyngitis. Moreover, this medication has a minimum number of contraindications.

Chemical composition

Lizobact is a drug with a combined biochemical composition. The table below lists the active ingredients of this drug.

Composition of Lizobact	Dosage
Lysozyme hydrochloride	The active substance of this medication, which has a protein structure. The concentration of this component is 20 mg.
Pyridoxine hydrochloride	The active substance of the antiseptic preparation Lizobakt. This component is also known under the more popular name vitamin B6. The dosage for pyridoxine is 10 mg.

The auxiliary function of the drug Lizobact is performed by the following chemicals:

• sodium saccharinate (sweetener) - 0.5 mg;
• gum tragacanth at a concentration of 10 mg;
• lactose monohydrate (milk sugar) - 155.4 mg;
• vanillin, which gives the drug a pleasant aroma - 0.1 mg;
• magnesium stearate, which prevents the disintegration of the drug to a powder state - 4 mg.

The main and auxiliary substances of Lizobact are absolutely safe for the human body. In the composition of this medication there are no dangerous preservatives, chemical stabilizers, toxic and carcinogenic compounds.

Release form

The drug Lizobact is available in the form of round white tablets with a slight yellowish tinge. On one or immediately on both sides of this medication, there are fractional inclusions in the form of dark particles. Antiseptic agent Lizobact is designed to be absorbed in the oral cavity. The preparation is packaged in polymer blisters of 10 tablets each. The main packaging of this medication is a cardboard box, inside which the manufacturer's instructions are enclosed.

Pharmacodynamics

Lizobact during pregnancy (1 trimester of fetal development excludes taking medications with a large number of side effects) does not have a pathological effect on the health of the child. The pharmacodynamics of this drug is due to its combined biochemical composition. Lysozyme is a protein-based enzyme substance.

In this case, there is a direct effect on gram-positive and gram-negative microorganisms, exhibiting the properties of a local antiseptic. This component disrupts the cell division of viral, bacterial and fungal microorganisms, reducing their numerical population.

Lysozyme destroys the pathogenic microflora, and also helps to increase the local immunity of the larynx and oral tissues. This component of the drug Lizobact is not absorbed into the local bloodstream, does not accumulate in the tissues of the throat, gums and tongue. The implementation of the pharmacodynamic properties of the substance lysozyme begins immediately after dissolution of the tablet in the patient's oral cavity. Pyridoxine has an antiphthous effect.

This component of the drug Lizobact protects the mucous membrane of the larynx and oral cavity from the consequences of the infectious process. This substance accelerates the regeneration of tissues and mucous membranes that have been damaged by pathogenic microorganisms.

Application for pregnant women

Lizobact during pregnancy (the 2nd trimester of fetal development requires high-quality nutrition and periodic intake of vitamin-mineral complexes) is taken only as directed by the attending physician. This medication is completely safe for the mother and baby. Lysobact is also used to treat women who are breastfeeding a newborn baby. The tablets of this medication slowly dissolve in the oral cavity until they are completely dissolved.

The drug Lizobact should not be chewed or swallowed whole. The dissolved tablets should be kept inside the mouth as long as possible. This will provide the maximum therapeutic effect from the action of their constituent substances.

The dosage regimen for pregnant women involves taking 1-2 tablets 3 to 4 times a day. The duration of the therapeutic process is determined individually depending on the type of throat, upper respiratory tract or oral cavity disease, but on average it is 8 days.

Contraindications

The drug Lizobact has a minimum number of medical contraindications.

This drug is not prescribed for admission in the following cases:

• individual sensitivity to the constituent substances of this medication, which is manifested by local or more extensive allergic reactions;
• congenital lactose intolerance, as well as systemic lactase deficiency;
• an allergic reaction to the protein of chicken eggs.

The drug Lizobact is contraindicated for use in children under 3 years of age. Patients who show signs of an allergic reaction after taking this drug should seek medical attention from their doctor.

Overdose

There is a minimal chance of an overdose with Lizobact tablets. This is due to the fact that this agent has a local effect without saturating the general blood flow. The appearance of signs of an overdose periodically occurs in patients who significantly exceed the therapeutic doses of Lizobact.

In this case, the following symptoms may be observed:

• numbness of the mucous membrane of the mouth and throat;
• the appearance of a feeling of tingling of tissues in the area of ​​application of the medication;
• loss of sensitivity of certain areas of the lower and upper extremities (the presence of this symptom indicates the absorption of a large number of constituent substances of Lizobact in the total blood flow).

Patients with signs of an overdose with Lizobact should immediately seek medical attention. To eliminate the above symptoms, patients are prescribed an abundant drink of large amounts of liquid. With the help of enhanced diuresis, the effect of rapid cleansing of the blood from the metabolic products of pyridoxine and lysozyme is achieved.

If necessary, gastric lavage is performed. If the water-electrolyte balance is disturbed, intravenous droppers with a saline solution and 5% glucose are prescribed. An overdose of Lizobact does not entail the onset of severe consequences or the occurrence of disturbances in the work of internal organs.

Side effects

Lizobact during pregnancy (the 3rd trimester of intrauterine development of the fetus is not a restriction for taking of this medication) is not prohibited from taking, but can cause side effects in the form of allergic reactions.

In case of individual intolerance to the constituent substances of this drug, the following symptoms may occur:

• angioedema of the mucous membranes of the larynx, which can cause a feeling of suffocation;
• hives;
• bronchial spasm, accompanied by a feeling of compression of the chest;
• redness and itching of the mucous membranes of the mouth, larynx;
• exudative erythema.

The appearance of signs of an allergic reaction to the constituent substances of Lizobact requires immediate medical attention. Patients with the above symptoms are admitted to an inpatient department of a hospital or receive outpatient treatment.

The main direction of therapy is taking medications that block the sensitivity of histamine H1 receptors. These are medicines Aleron, Loratadin, Tsetrin, Suprastin. In conditions of an acute allergic reaction, when the patient shows signs of angioedema, the non-steroidal anti-inflammatory drugs Dexamethasone or Prednisolone are used. These medicines are intended for injection.

Special recommendations

When symptoms of a moderate or acute allergic reaction appear, further administration of Lizobact is stopped. The constituents of this drug do not affect the central and peripheral nervous system, do not inhibit the thought process and do not cause drowsiness. During therapy with Lizobact, it is allowed to drive vehicles, complex mechanisms, technological equipment, and perform work with increased danger.

Drug interactions

Lizobact during pregnancy (1 trimester of fetal development is not a reason for canceling this medication) is taken during a continuous therapeutic course.

This drug is distinguished by the following forms of drug interactions:

• enhances the pharmacological properties of antibacterial agents based on chloramphenicol, penicillin series, as well as antimicrobial medicines containing nitrofurantoin;
• weakens the biochemical activity of levodopa;
• oral contraceptives with the addition of estrogens and drugs from the group of immunosuppressants increase the patient's need for pyridoxine;
• enhances the effect of diuretic drugs, increasing the physiological load on the kidneys.

Before starting therapy with the antiseptic agent Lizobact, the patient must inform his attending physician about all the medications he is currently taking. This will avoid negative drug interactions, and also minimize the risk of side effects.

Storage conditions and periods

The drug Lizobact is stored in a dry, cool and well-ventilated room at an air temperature not exceeding +25 degrees Celsius. This medication should be left in the original manufacturer's packaging, out of the reach of children. The general shelf life of Lizobact tablets is 5 years, after which the drug is prohibited.

Conditions of dispensing from pharmacies

The drug Lizobact is dispensed without a prescription from the attending physician. The price of this medication in pharmacies is from 240 to 273 rubles. per pack of 30 tablets.

Analogs

On the pharmaceutical market, there are other antiseptic agents for absorption in the oral cavity, which are analogs of the drug Lizobact.

ZOTT

The drug ZOTT is produced by the Indian pharmaceutical company Unicue Pharmaceutical Laboratories.

This medication is an analogue of the drug Lizobact, and it contains the following substances:

• pyridoxine at a concentration of 10 mg;
• lysozyme in a dosage of 20 mg.

ZOTT belongs to the pharmacological group of local antiseptic agents with a combined biochemical composition.

This drug has the following indications for use:

• diseases of the oral mucosa, gum tissue and throat, which are caused by infectious microorganisms;
• herpetic ulceration;
• bacterial, viral and fungal diseases of the upper respiratory tract.

The antiseptic agent ZOTT helps to restore damaged areas of the oral mucosa, increases local immunity and promotes faster recovery. The dosage regimen with this medication involves taking 1-2 tablets from 3 to 4 times a day. The duration of the therapeutic course is 8 days. The drug ZOTT is approved for use in the treatment of pregnant women and mothers who are breastfeeding.

The drug ZOTT is contraindicated for admission to patients with individual intolerance to its constituent components. In this case, the appearance of local or more extensive allergic reactions of the body is possible. If symptoms of itching of the oral mucosa, reddening of the throat, urticaria and edema of epithelial tissues appear, further use of this medication must be stopped.

Lorolizin

Lorolizin is a domestic analogue of the drug Lizobakt. This medication is produced by the Russian enterprise CJSC Obninsk Khimfarm Company.

The active ingredients of this medicinal product are the following chemicals:

• lysozyme with a mass fraction of 20 mg;
• pyridoxine at a concentration of 10 mg.

Lorolizin tablets are indicated for use in dentistry, as well as for the relief of inflammatory processes in the upper respiratory tract.

This medication is used in the complex treatment of the following diseases:

• gingivitis;
• ulcerative formations on the oral mucosa, which are caused by the herpes virus;
• stomatitis of an infectious origin;
• inflammatory processes in the upper respiratory system.

The drug Lorolizin has antimicrobial, regenerating and anti-inflammatory properties. This remedy is taken 1-2 tablets 3-4 times a day. The total duration of treatment is at least 8 days.

The drug Lorolizin is completely safe for the body of pregnant women and the developing fetus. The constituents of this medication are not absorbed into breast milk. In this regard, Lorolysin can be used during lactation. The average cost of this drug in pharmacies is 281 rubles.

FluCold ENT

FluCold ENT antiseptic agent is produced by the Russian pharmaceutical company Kanonpharma Production CJSC. This medicine comes in the form of white tablets to be sucked into the mouth.

The active substances of FluCold ENT are lysozyme hydrochloride at a dosage of 20 mg, as well as the vitamin component of pyridoxine hydrochloride in an amount of 10 mg. This tool is used in therapeutic practice by dentists and otolaryngologists for the treatment of inflammatory and infectious pathologies of the mucous membrane of the mouth, larynx and gums.

FluCold ENT suppresses bacterial, viral and fungal infections. This medication is effective in clinical cases where multiple oral ulcerations are caused by severe herpes. The constituents of FluCold ENT tablets do not have a negative effect on the body of the mother and the child at the stage of intrauterine development. Therapeutic doses of this medication are 1-2 tablets, which are taken 3-4 times a day. The terms of treatment are 8 days.

FluCold ENT tablets should not be chewed or swallowed whole. This tool only needs to be absorbed, keeping it inside the oral cavity for a maximum amount of time.

In patients with individual sensitivity to the active substances of this medication, allergic reactions may occur. Symptoms in the form of skin redness, itching and swelling of the oral mucosa, the appearance of urticaria are grounds for discontinuing further therapy with FluCold ENT tablets.

Lizobact is an antiseptic agent of the local spectrum of action, which contains the active components lysozyme and vitamin B6. This medication is approved for use by women in the 1st, 2nd and 3rd trimester of pregnancy. The active substances of this drug are completely safe for the body of the expectant mother and the developing fetus.

At the same time, Lizobact also has no restrictions in its use by patients who breastfeed a newborn baby. Vitamin B6, which is part of these tablets, only accelerates the healing process of the oral mucosa. In case of violation of the established dosing rules with Lizobactom, an allergic reaction may occur.

Video about the drug Lizobact

Lizobact for sore throat, sore throat: