- Composition and dosage form
- Indications for the use of Miramistin during pregnancy
- Can Miramistin go down the throat during pregnancy?
- How does it affect the fetus
- Treatment features
- Instructions for Miramistin throat during pregnancy
- Contraindications for use during pregnancy
- Video about Miramistin during pregnancy
Most medications are contraindicated during pregnancy, even with a simple cold or acute respiratory viral infection, due to a direct or indirect negative effect on the development of the fetus or the course of pregnancy. And also the infection itself has a negative effect if it is not stopped in time. A simple and safe drug in the treatment of the oral cavity, throat and nasopharynx is Miramistin, which can be used even by women in the 1st, 2nd or 3rd trimester pregnancy.
Composition and dosage form
Miramistin belongs to antiseptic and disinfectants. It comes in the form of a rinse solution or a topical spray. It is colorless or slightly yellowish, transparent, odorless and neutral in taste. When shaking the bottle, a slight foaming of the solution may be observed. The active ingredient is 0.1 mg miramistin (benzyldimethyl-myristoylamino-propylammonium chloride). The additional substance is sterile water.
Bottles with rinsing solution are produced in 50, 100, 150 ml. In the form of a spray, the cans have 50 and 100 ml.
Indications for the use of Miramistin during pregnancy
Miramistin during pregnancy is prescribed for the prevention of acute respiratory viral infections during a period of increased risk of the disease or to eliminate the first symptoms of the disease.
It is also used in the complex therapy of the following pathologies:
- acute or chronic tonsillitis;
- acute or chronic pharyngitis;
- periodontitis and periodontal disease;
- oral candidiasis;
The drug is highly effective against most pathological microorganisms, namely:
- gram positive and gram negative bacteria;
- aerobic and anaerobic bacteria;
- monocultures and microbial associations, including hospital strains;
- ascomycete fungi;
- yeast fungi.
The effectiveness of Miramistin lies in its direct interaction with the lipids of the membrane wall of microorganisms, which leads to their fragmentation and destruction. The enzymatic activity of the microbial cell changes, which contributes to the suppression of the viability of microbes and their cytolysis. Miramistin is highly effective in the prevention of secondary infection after removal of the tonsils.
It is also successfully used in other areas of medicine:
Can Miramistin go down the throat during pregnancy?
The drug has undergone a number of studies when prescribing it to pregnant women. When testing it, no direct side effects were found on the course of pregnancy, fetal development, as well as any teratogenic effects. But in the 1st and 2nd trimester of pregnancy, when the nervous, cardiovascular, herbal systems of the fetus are formed, the drug should be prescribed only taking into account the risk-benefit ratio for the mother and the child.
Miramistin during pregnancy in the 3rd trimester in the throat is absolutely safe, since it acts locally in the area of its spraying. It does not penetrate the mucous membranes and the blood-brain barrier, which protects the fetus from exposure to the drug.
The solution has practically no effect on the membranes of human cells, but has a high selective effect on microorganisms.
There is no resorption of the drug, so it is allowed to use it by pregnant women, as well as breastfeeding women.
How does it affect the fetus
The effect of medications on the fetus is due to their ability to penetrate the blood-brain barrier. Miramistin does not have this ability. Its molecules accumulate in the membrane of microorganisms, increase their susceptibility to high-molecular substances, change the enzymatic composition of the microbial cell, which leads to its cytolysis.
Miramistin during pregnancy in the 3rd trimester in the throat is used in the form of a spray or solution. Clinical studies confirm that local use of the solution does not have a negative effect on the fetus, therefore it is safe. The drug destroys streptococci, staphylococci, Klebsiella, as well as fungal infections. Having destroyed the focus of infection, its impact on the body is also prevented, as well as negative consequences in the development of the child.
The drug is allowed to be taken by pregnant and lactating women.
Miramistin does not affect concentration, does not cause a hypnotic effect, therefore it is safe when driving or other vehicles. Its use when engaging in potentially hazardous activities or with increased mental activity does not in any way affect the results of work. It has been proven that the speed of psychomotor reactions does not change when using Miramistin.
When combined with an antibiotic, Miramistin increases its effect, since the resistance of microorganisms to the antibiotic decreases. This is due to the effect of the drug on the cell membrane of microbes.
Usually, the drug is well tolerated and does not cause adverse reactions. But some people with sensitive mucous membranes may experience sensations slight burning sensation in the area of application of the solution, which quickly disappears on its own (in average 20-30 sec.). This feature does not require additional intervention or drug withdrawal.
Miramistin has the following abilities:
- reduces swelling of the mucous membranes;
- improves local immunity;
- restores the protective functions of the mucous membranes;
- moisturizes the throat;
- prevents or relieves coughing;
- has a mild analgesic effect, which alleviates the symptoms of the disease;
- normalizes the respiratory tract;
- prevents infection and progression of the disease;
- improves the regenerative processes of the mucous membrane;
- reduces inflammation of the throat, larynx and oral cavity;
- increases the effectiveness of antibiotics.
Instructions for Miramistin throat during pregnancy
Miramistin, prescribed to a pregnant woman in the 1st, 2nd or 3rd trimester of pregnancy for the treatment of inflammatory diseases of the throat or oral cavity, is used in two versions - in the form of a spray or solution for rinsing.
In order to use the spray correctly and effectively, you must act step by step according to the instructions:
- Remove the can from the box.
- Shake it several times to avoid sediment formation.
- Remove the protective cap from the sprayer.
- Straighten the spray and direct it to the desired spray location (throat, mouth, nose).
- Hold the flexible tube in your mouth and hold your breath.
- Pressing the cylinder head, spray the spray 2-3 times, capturing the desired area of the mouth or throat.
During the procedure, the can with the liquid should be kept upright, not turned over to a horizontal position or upside down.
In order to use the solution correctly, you should adhere to the following procedure for the procedure:
- Remove the bottle from the box.
- Shake it 2-3 times and unscrew the cap.
- Pour 10-15 ml of the solution into a clean glass.
- Pour liquid from the glass into the mouth and rinse the throat, holding it inside for 20-30 seconds.
- Spit out the solution.
- Repeat the procedure, distributing the liquid in the glass 2-3 times.
For the effectiveness of treatment, after using a solution or spray, you should not drink, eat or rinse your mouth with other solutions for 15-0 minutes.
For different forms of infection, Miramistin is used in different forms and with the frequency recommended by the doctor.
|Pathology||Drug form||Receive frequency|
|Tonsillitis||Spray||3-4 times a day, 3 sprays for each tonsil.|
|Pharyngitis||Spray or solution||3-4 times a day for 2-3 sprays into the throat or gargle 2-3 times.|
|Stomatitis, gingivitis||Solution||Rinse 4-5 times a day, keeping the liquid in the mouth for a few seconds.|
|Candidomycosis||Solution or spray||2-4 times a day.|
After opening the bottle, store in a dark place at a temperature not exceeding 25 ° C. It is not necessary to keep it in the refrigerator and cannot be frozen, since the molecules of the active substance are destroyed when frozen or heated.
Contraindications for use during pregnancy
Miramistin during pregnancy in the 3rd trimester in the throat is easy and safe to use. During this period, practically no side effects of the drug were revealed. It is also safe in the 1st and 2nd trimesters of pregnancy, but it is used less frequently. Scientific studies have shown that the drug does not affect the embryo, since it is not absorbed through the mucous membranes.
Direct contraindications include increased individual sensitivity to Miramistin, which is rarely observed. It is also undesirable to use the remedy for children under 3 years of age, since studies at this age on the tolerance of the drug and the characteristics of treatment have not been sufficiently studied. Treatment at this age can be carried out only after being prescribed by a doctor, having studied all the risks and benefits for the child.
Among the side effects, the most common is a burning sensation at the site of application of the solution. But it quickly passes and does not make the patient much discomfort. To avoid misuse of Miramistin and self-withdrawal through this symptom, the patient should be warned about possible sensations before prescribing the drug.
In case of an overdose of the drug, hoarseness of the voice may occur. By adhering to the recommendations for the use of the drug, this side effect can be avoided.
There are also known cases of skin rash after using Miramistin. This rarely happens and is associated with increased individual sensitivity to the active substance.
During pregnancy, it is difficult to determine the choice of treatment for viral diseases, and also inflammatory processes of the throat, larynx, oral cavity and decide whether to treat them at all medicines. But the infection can quickly progress and worsen the condition of not only the mother, but also the child. Therefore, a safe, reliable and simple solution for diseases of the upper respiratory tract or throat in the 1st, 2nd or 3rd trimester of pregnancy is treatment with Miramistin.
Video about Miramistin during pregnancy
Miramistin during pregnancy: