Pantogam Active 300. Reviews, instructions for use, price

Pantogam Active is a drugused for cognitive neurological problems. The drug in a dosage of 300 mg has an average cost and numerous positive reviews.

Release form

The drug is produced in Russia in the form of capsules for systemic use. The capsules are white and hard. Their filler is white or with a yellow tint.

The product is contained in blisters and sealed in cardboard boxes.

Chemical composition

The main ingredient of the product is D, L-hopantenic acid.

Additional composition:

• MCC;
• magnesium stearate;
• gelatinous filler;
• food additive E.

All substances are combined with each other and enhance the effect of the active ingredient.

Pharmacological properties

The drug belongs to the class of nootropic drugs that have additional anticonvulsant and anti-anxiety effects.

Since the active ingredient contains gamma-aminobutyric acid (GABA), the drug has a direct effect on these receptors. Moreover, the improvement in the interaction and transport of the ingredient with the GABA receptors is due to the hopantenic acid contained in the drug and its isomers.

Unlike similar 1st generation drugs, capsules have a more pronounced nootropic effect and are effective against seizures.

The systematic intake of the drug leads to an increase in the resistance of the brain to toxic damage and the prevention of oxygen starvation. It also helps stimulate anabolic reactions in neurons.

The drug has a moderate sedative effect. The capsules help to eliminate anxiety and prevent the development of asthenic conditions, reduce motor activity and normalize behavioral ability.

The medicine increases intellectual and physical activity. It also helps to reduce excessive muscle tone and bladder reflex.

Pharmacodynamics and pharmacokinetics

When used orally, it is rapidly and almost completely absorbed from the gastrointestinal tract. The drug is able to penetrate the blood-brain barrier. The drug does not lend itself to metabolic transformation and leaves the body unchanged within 2 days. Approximately 70% is excreted in the urine. About 30% of the product leaves the body through defecation.

Indications for use

Pantogam Active 300 (reviews of the drug are mostly positive and recommend it for purchase) is used in the treatment of various disorders with neurological or vascular etiology.

Indications:

• organic brain diseases and neurotic disorders accompanied by cognitive disorders (including neuroinfectious lesions, trauma);
• cerebrovascular insufficiency due to the deposition of atherosclerotic plaques in the region of the vascular system of the brain;
• extrapyramidal disorders, including forms provoked by the use of neuroleptic drugs;
• epileptic seizures (in combination therapy with anticonvulsant drugs);
• psychoemotional disorders, decreased intellectual and physical capabilities, decreased concentration of attention;
• problems with urination caused by neurogenic factors;
• schizophrenia (complex treatment of the disease).

The tool should be used only after making or clarifying the diagnosis.

Contraindications

If there are contraindications, a different treatment must be used.

Contraindications:

• intolerance to ingredients;
• minor age;
• carrying a child;
• lactation period;
• kidney disease, occurring in acute and severe form.

Before taking the capsules, you should undergo a diagnosis to determine the sensitivity to the components.

At what age can the drug be used?

The medication is not used in pediatric practice. The minimum age is 18 years old.

Instructions for use, dosage

The medicine is indicated for systemic use. Take capsules immediately after eating (after 15-20 minutes).

Dosages: 1-3 pcs. from 2 to 3 times a day. In this case, the remedy is recommended to be taken in the morning or afternoon.

The maximum daily dose should not exceed 8 capsules.

The duration of therapy is from 1 to 4 months. In more rare cases, treatment can be carried out within six months or a year.

If necessary, repeated courses can be prescribed.

Side effects

Pantogam Active 300 (drug reviews warn about the possible development of side effects) in most cases is well tolerated by patients and does not cause addiction or withdrawal syndrome.

Negative manifestations occur in extremely rare cases and can be triggered by the action of the active substance on the patient's body.

Side effects:

• Immunity dysfunctions: signs of allergy. In addition to skin reactions, rhinitis or conjunctivitis may occur.
• Mental disorders: sleep disturbances (insomnia or, conversely, increased sleepiness).
• Changes in the work of the central nervous system: tinnitus, attacks of dizziness, migraines.
• Gastrointestinal disorders: nausea, soreness in the abdomen.

With the development of these or any other symptoms, it is necessary to interrupt further therapy and seek medical advice.

Overdose

When taking higher dosages, undesirable symptoms may develop. Most often, the use of high doses of the drug leads to increased side effects.

In the event of the development of such signs, it is necessary to contact a medical institution for appropriate therapy (according to the symptoms that have arisen).

It is self-recommended to take activated charcoal.

In severe forms of poisoning, gastric lavage should be performed. As a rule, the effectiveness of the technique is noted in the first 1-2 hours after the development of an overdose.

special instructions

If dizziness develops, it is recommended to refrain from driving or performing other work associated with increased concentration of attention or the speed of psychomotor reactions.

Pantogam Active 300 (expert reviews of the drug are positive and recommend it for use) is prohibited use simultaneously with other similar agents, as this can cause various negative reactions.

Drug interactions

The drug can interact with other drugs.

Thus, the following effects and actions are noted:

• Barbiturates - an increase in the action and activity of this group of medicines.
• Anticonvulsants - increasing their effects.
• Phenobarbital, carbamazepine, antipsychotics - reduces the risk of side effects of these drugs.

An increase in the action and effectiveness of the main agent is observed when it is used simultaneously with glycine or etidronic acid.

The main agent enhances the effect of local anesthetic drugs.

When taking other medications during the period of prescribing the main drug, you should inform the specialist in advance.

Analogs

Pentogam Active can occasionally cause the development of intolerance reactions, especially in cases of exceeding dosages (over 300 mg at a time). In this regard, it can be replaced by other similar drugs. In this case, the physiological characteristics of the patient and the severity of the disorder should be taken into account. Additionally, you can read the reviews of people who took the pills.

The choice of a replacement should only be dealt with by a specialist who is familiar with the characteristics of the patient's illness.

Amilonosar (Russia)

This tool is produced in the form of tablets for systemic use. N-nicotinoyl-gamma-aminobutyric acid sodium salt is used as an active ingredient. Drug group psychostimulating and nootropic drugs.

Recommendations for use:

• cerebrovascular insufficiency;
• asthenic syndrome;
• depression (for elderly patients);
• violations that are accompanied by fear, anxiety, irritability and other psycho-emotional factors;
• ethanol poisoning (including chronic alcoholism);
• headaches, neuroinfections and head injuries;
• excessive physical and mental stress (including in sports practice);
• open-angle glaucoma (to improve vision);
• problems with urination (for children).

Dosages: depending on the violation, from 40 to 200 mg per day, divided into several doses. The duration of the course is according to the testimony of a doctor, from 1.5 weeks to six months.

Restrictions on use:

• allergy to the composition;
• pregnancy;
• lactation period;
• chronic kidney failure.

Adverse reactions are extremely rare and can be expressed in the following symptoms:

• irritability;
• increased excitability;
• anxious states;
• migraines and dizziness;
• nausea;
• skin reactions - rash, itchy elements.

Method of sale - the medicine is subject to prescription. Price - from 160 rubles.

Gliatilin (Italy)

Pantogam Active 300 (reviews of similar medicines can differ significantly from each other) can be replaced with both domestic medicines and foreign-made means. For example, the drug Gliatilin, which is made in the form of oral capsules.

The main ingredient is choline alfoscerate. The drug is a representative of the nootropic group of drugs with cholinomimetic activity.

Indications for admission:

• circulatory disorders in the brain;
• organic psychosyndrome caused by various age-related and degenerative disorders in the brain;
• cognitive disorders (for elderly patients) - confusion, disorientation in space, decreased motivation and concentration, lack of initiative;
• cerebrovascular insufficiency (as elimination of consequences and complications);
• behavioral disorders associated with age-related changes - irritation, lack of interest, unstable emotional state;
• pseudomelancholia (senile form of the disease);
• dementia due to myocardial infarction.

Dosing rules: 1 capsule 2-3 times a day before meals.

The duration of therapy is according to the testimony of a specialist, according to the diagnosis. In this case, the duration can be adjusted if necessary.

The medication is prohibited for use in the following cases:

• intolerance to ingredients;
• pregnancy;
• period of breastfeeding;
• minor age.

The medicine rarely leads to the development of negative symptoms associated with its use.

The most common reactions are:

• nausea (dosage adjustment downward is required);
• allergic manifestations;
• pain in the abdomen;
• confusion (usually short-lived).

Dispensing method - by prescription. Price - from 650 rubles.

Phenibut (Russia)

This generic comes in pill form for systemic use. The active ingredient is aminophenylbutyric acid hydrochloride.

The drug is a representative of the class of nootropic drugs and is prescribed for the development of the following disorders:

• asthenic syndrome;
• anxiety-neurotic disorders - fear, psychopathy, anxiety disorder, obsessional neurosis;
• stuttering and nervous tics (for children), including urination disorders caused by neurotic factors;
• sleep disturbance (insomnia) - for elderly patients;
• Meniere's syndrome (dizziness caused by the development of disorders in the vestibular system);
• Air sickness or motion sickness (as a prophylaxis);
• open-angle glaucoma (complex treatment);
• alcoholism (adjuvant therapy).

Dosing features (for adults): from 20 mg to 0.75 g. Children are prescribed from 20 to 250 mg. Dosages are determined individually according to the identified form of violation, as well as the severity of the pathological process. The duration of the course is individual, based on the established diagnosis. A contraindication to taking capsules is intolerance to the components.

With extreme caution and only under the supervision of a physician, a medication can be prescribed under the following conditions:

• liver failure;
• carrying a child;
• lactation period;
• the presence of ulcers and erosions in the gastrointestinal tract.

Adverse reactions are extremely rare and can manifest themselves in the form of the following symptoms:

• dizziness and migraine;
• excited state;
• anxiety;
• increased sleepiness;
• nausea;
• rashes on the skin;
• itchy elements.

Terms of sale - prescription.

Cost - from 250 to 600 rubles.

Other similar remedies

The drug has other analogues that have a similar effect and belong to the same pharmacological group.

List of funds:

• Picamilon (Russia) - tablets for oral administration
• Betaserc (Switzerland) - tablets for oral administration.
• Hopantenic acid (Russia) - tablets for course administration.
• Cortexin (Russia) is a lyophilisate for intramuscular administration.
• Lucetam (Hungary) - tablets or solution.
• Pantocalcin (Russia) oral solution or tablets.
• Piracetam (Russia) - capsules for oral administration or solution for intravenous / intramuscular administration.
• Citicoline (Russia) - solution for intramuscular or intravenous administration.

Most remedies are prescription drugs available from pharmacies.

Terms, conditions of sale and storage

• The capsules should be stored in a dark and dry place at temperatures up to 25 ⁰C.
• Expiration date - 3 years from the date of issue.
• Do not use after the expiration date stated on the package.
• Dispensing method - prescription.

Price

The prices for the product may vary slightly depending on the region of sale and the pharmacy trade network. You can clarify the availability of the drug, as well as find out its cost at any pharmacy located at the place of residence.

Region / region	Dosage form / dosage	Price
Moscow, Moscow region	Capsules, 300 mg (60 pcs.)	RUB 470-620
St. Petersburg	RUB 500-585
Saint Petersburg (suburbs)	RUB 490-615
Leningrad region	RUB 525-565
Novgorod region	530-580 rub.

Before taking Pantogam Active (300 mg), it is required to read the instructions for using the tablets and consult a doctor. Additionally, it is recommended to study the reviews of patients who have already used the drug.

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