Burana 400 mg tablets from Finland. Price, instructions for use

Burana (400 mg) - this medicine is from Finland, which is widely used in medical practice for inflammatory diseases. The tablets have a pronounced therapeutic effect and are highly appreciated by specialists and patients.

Release form

The medicine is produced in Finland in the form of tablets for systemic use. They are round and white or off-white.

The product is packaged in blisters or plastic bottles. It is packed in cardboard boxes.

Chemical composition

Ibuprofen is the main ingredient.

Additional composition:

• MCC;
• pregelatinized starch;
• food additive E551;
• dextrates;
• primlose;
• milk sugar;
• magnesium stearate;
• food additive E171;
• polysorbate 80;
• 85% glycerol;
• hypromellose.

All components are combined with each other and enhance the effect of the main substance.

Pharmacological properties

The drug is a representative of a non-steroidal anti-inflammatory group of drugs (NSAIDs). The drug relieves inflammatory reactions, helps to eliminate pain and fever.

The action of the drug is aimed at suppressing the activity of COX, a component responsible for the development of pain and inflammation. The analgesic effect occurs due to the peripheral and central mechanism of action of the agent. It inhibits platelet adhesion.

Pharmacodynamics and pharmacokinetics

The tablets are completely absorbed from the gastrointestinal tract. With the consumption of food, the absorption rate decreases. The active substance lends itself to metabolic transformation in the liver. The half-life is from 2 to 3 hours. About 80% of the drug leaves the body together with urine, mainly in the form of metabolites (about 70%). Approximately 10% of the drug leaves the body unchanged. 20% of the drug is excreted through the intestines.

Indications for use

The drug has a wide list of recommendations for admission.

Indications:

• inflammatory reactions and degenerative changes in the articular system and spine;
• disorders in the articular system with relapses of gout;
• radiculitis;
• inflammatory processes in the area of ​​soft tissues and the musculoskeletal system, caused by injuries;
• psoriatic arthritis;
• painful sensations caused by inflammatory diseases of the mouth, throat, nose;
• myalgia;
• inflammation of the tendons;
• bursitis;
• ankylosing spondylitis;
• salpingo-oophoritis;
• pain during menstruation;
• migraine;
• toothache;
• feverish conditions caused by infectious and inflammatory processes;
• childhood infectious diseases;
• reactions in children due to vaccination.

The drug should be used only in the presence of these conditions.

Contraindications

Burana (400 mg) - tablets from Finland, which have numerous restrictions on their use.

Contraindications:

• intolerance to the components;
• the presence of erosions, ulcers and bleeding in the stomach;
• heart failure (a severe form of the disorder);
• functional disorders of the kidneys and liver, proceeding in a pronounced form;
• hematopoietic disorders;
• aspirin triad;
• rehabilitation after bypass surgery;
• the presence of bleeding of various localization;
• diathesis (hemorrhagic type of disease);
• coagulation disorders;
• 3rd trimester of pregnancy.

  

With extreme caution, the medication can be used in the following cases:

• bleeding due to the presence of ulcers and erosions in the stomach (in a single case);
• other diseases of the gastrointestinal tract - gastritis, colitis (including the ulcerative form of the disorder), enteritis, Helicobacter;
• bronchial asthma;
• various forms of allergies (relapses);
• systemic lupus erythematosus, Sharpe syndrome;
• kidney failure;
• chickenpox;
• increased content of bilirubin;
• cirrhosis of the liver;
• renal syndrome;
• heart failure;
• chronic high blood pressure;
• cerebrovascular disorders;
• diseases of the circulatory system of unknown origin;
• psychosomatic disorders (severe forms of pathologies);
• an abnormal increase in the level of lipids and lipoproteins;
• diabetes;
• damage to peripheral arteries;
• smoking;
• alcohol abuse;
• advanced age;
• lactation period;
• 1st and 2nd trimester of pregnancy.

In the presence of these conditions, therapy is carried out only under the supervision of a specialist.

At what age can the drug be used?

The tablets can be used in therapy in children. The minimum age thresholds are from 3 months.

Instructions for use, dosage

The tool is intended for systemic use.

• Dosages for adults and children over 6 years old: 0.2-0.4 g from 3 to 4 times a day.
• Dosing features for children from 3 months to 6 years: based on the child's body weight or 50 mg 3 times a day.

Duration of use - according to the instructions of a specialist.

Side effects

Burana (400 mg) - tablets from Finland, which must be taken strictly according to the instructions in the instructions or as recommended by a doctor. Negative signs caused by taking the medication develop in extremely rare cases and may be due to violations of the rules of use.

Side effects:

• Hematopoietic dysfunction: anemic conditions, decreased production of leukocytes, platelets, red and white blood cells.
• Immune disorders: allergies, anaphylactic reactions, respiratory system disorders, skin manifestations, allergic rhinitis, increased concentration of eosinophils. Swelling, shortness of breath, hypotension may also occur.
• Digestive Disorders: soreness in the abdomen, dyspeptic disorders, ulcerative lesions and the presence of perforations in the stomach. In more rare cases, it can develop vomiting of blood, bleeding in the stomach, tarry stools (extremely rarely, it can be fatal). The development of ulcerative stomatitis, gastritis, Crohn's syndrome is also noted. Occasionally, colitis worsens.
• Liver and biliary tract: functional disorders of the liver, hepatitis, hyperbilirubinemia, increased activity of liver enzymes.
• Urinary system: kidney failure (aggravated course of the disease), blood formation and increased levels proteins in urine, nephrotic syndrome, bladder inflammation, nephritis (interstitial form violations). In more rare cases, the development of papillary necrosis is noted.
• Nervous system: migraines, meningitis (aseptic type of pathology).
• CCC: heart failure, edema, increased risk of consequences in case of blood clots, increased blood pressure.
• Respiratory system: spasms in the bronchi, the development of shortness of breath and bronchial asthma.
• Changes in indicators during research: a decrease in the concentration of hemoglobin and hematocrit, an increase in the period of bleeding, a decrease in sugar, an increase in the activity of liver enzymes.

In these conditions, it is required to discontinue therapy and seek medical advice.

Overdose

When taking higher doses, undesirable symptoms may develop.

Overdose:

• soreness in the abdomen;
• inhibited state;
• nausea and vomiting;
• increased sleepiness;
• migraine;
• depressive conditions;
• kidney failure (acute course);
• hypotension;
• noise in ears;
• various types of arrhythmias (including atrial fibrillation);
• metabolic acidosis;
• an increase in the level of potassium in the blood;
• coma;
• cessation of breathing.

In the event of the development of the listed signs, you should contact a medical facility for symptomatic therapy. As a treatment, gastric lavage, sorbents and alkaline drinks are prescribed.

In more difficult cases, forced diuresis is performed and other means are used to eliminate negative manifestations (normalization of acid-base balance and blood pressure).

special instructions

Finnish Burana tablets must be taken with precautions. In this case, one should strictly adhere to the established dosages, since each dose (200 and 400 mg) has its own characteristics of administration.

Treatment with the drug should be carried out in short courses and minimal dosages. When using tablets for more than 1.5 weeks, mandatory consultation with a specialist is required.

With prolonged use of the medication, it is necessary to regularly diagnose blood functions and the condition of the kidneys and liver. In case of changes, additional studies are required - a general blood test, EGDS, a study of feces for the presence of bloody impurities.

The drug for chickenpox can lead to severe infection and the development of complications. It is necessary to avoid the use of tablets during this period.

The medication can have a depressing effect on cyclooxygenase and prostaglandins. It can lead to reproductive disorders in women.

If any negative symptoms develop, it is recommended to refuse to drive or perform other work with increased psychomotor function.

Drug interactions

The drug can interact with other medicines.

Medicines and their interactions:

• Antihypertensive drugs, diuretics - reducing their action.
• Glucocorticosteroids - an increase in the risk of adverse reactions from the gastrointestinal tract.
• Anticoagulants - increasing their action.
• Derivatives of sulfonylureas or hydantoins, indirect anticoagulants, hypoglycemic agents (for systemic use) - a violation of the compounds of the components of the funds with blood proteins.
• Amlodipine - a slight decrease in the hypotensive effect.
• Aspirin - lowering the level of the main drug.
• Baclofen - increasing its toxicity.
• Warfarin - an increase in the period of bleeding, the formation of blood in the urine and bruising.
• Captopril - a decrease in its hypotensive effect.
• Cholestyramine - a decrease in the absorption of the main agent.
• Lithium carbonate - increasing lithium levels.
• Magnesium hydroxide - increasing the absorption of the main agent.
• Methotrexate - increasing its toxic effect.
• Cardiac glycosides - an increase in their level in the blood, worsening of the condition of patients with heart failure.
• Cyclosoprine - an increased risk of kidney toxicity.
• Mifepristone - a decrease in its effectiveness.
• Zidovudine - an increase in toxic blood damage, the formation of hematomas.
• Tacrolimus - an increased risk of kidney toxicity.
• Quinolines - an increase in the risk of developing a convulsive state.
• Myelotoxic drugs - an increase in the toxic effect on the blood.
• Cefamandol, cefoperazone, cefotetan, plikamycin, valproic acid - an increased risk of developing coagulation factor deficiency.
• Calcium channel blockers - a decrease in absorption and an increase in the level of the main drug.
• IMO - an increase in the formation of metabolites, an increase in the risks of toxic damage to the body.

When taking these funds, you should inform your doctor in advance.

Analogs

Burana (400 mg) - tablets from Finland, which occasionally can cause the development of intolerance reactions.

Similar drugs are prescribed when the main drug is poorly tolerated. In this case, the physiological characteristics of the patient and the severity of the disorder should be taken into account.

The choice of a replacement should only be dealt with by a specialist who is familiar with the characteristics of the patient's illness.

Ketonal (Slovenia)

The medication is produced in the form of tablets based on ketoprofen. Pharmacological group - NSAIDs. It is prescribed for inflammatory and degenerative diseases of the articular and muscular system, for pain of various etiologies and elimination of temperature.

Take the medicine 1 capsule 3 times a day, but not more than 0.2 g. The duration of the course is according to the testimony of a specialist. The tool has multiple restrictions on its use, so it is recommended that you familiarize yourself with this list in advance. The medicine is not prescribed for children and pregnant women (3rd trimester). Terms of sale - without a prescription. Price - from 200 to 600 rubles.

Diclofenac (Russia)

The medicine is available in the form of tablets for systemic use. The active ingredient is sodium diclofenac. The drug is used for various inflammatory diseases accompanied by pain and fever. Dosages: from 75 to 150 mg per day, divided into 2 equal doses. The duration of use depends on the identified pathology and is set individually.

The remedy has numerous contraindications, which you should familiarize yourself with in advance. The minimum age limit is for children over 6 years old. Tablets can be prescribed during pregnancy, with the exception of the 3rd trimester. They are also prohibited for breastfeeding. Vacation rules - over the counter. Cost - from 35 rubles.

Ibuprofen (Russia)

The medication is produced in the form of tablets for systemic use. The main substance is ibuprofen. Indications for the use of the drug are various inflammatory diseases, accompanied by the development of pain syndrome and an increase in body temperature. It can also be prescribed for menstrual and childhood infections.

Dosage regimen: from 0.2 to 0.4 g per day. It is recommended to divide the dose into several equal doses. The drug has many different contraindications, therefore, mandatory familiarization with them is required. The tablets are not used in the 3rd trimester of pregnancy. Application in childhood is possible.

Dispensing method - over-the-counter. Cost - from 80 rubles.

Other similar means

Burana (400 mg) - tablets from Finland, which have many other similar drugs.

List of funds:

• Dexalgin.
• Dexketoprofen.
• Dyclogen.
• Indomethacin.
• Ketoprofen.
• Meloxicam.
• Melbek.
• MOMENT.
• Naisulid.
• Nimesulide.
• Nurofen.
• Piroxicam.
• Flamax.

Most of these medicines are available over the counter.

Terms, conditions of sale and storage

• The medicine should be stored in a dark and dry place at a temperature of 15 to 25 ⁰C.
• Expiration date - 5 years from the date of issue. Do not use after the expiration date stated on the package.
• The way of implementation is without a prescription.

Price

The prices for the drug may differ slightly from each other depending on the region of sale and the pharmacy trade network. You can clarify the availability of tablets on sale, as well as find out their cost, at any pharmacy located in your place of residence.

Region / region	Dosage form / dosage	Price
Moscow, Moscow region	Tablets, 10 pcs.	From 1480 rub.
St. Petersburg	From 1550 rub.
Saint Petersburg (suburbs)	From 1500 rub.
Leningrad region	From 1540 rub.
Novgorod region	From 1550 rub.

Before using Buran (400 mg), it is necessary to read the instructions for use of the tablets and consult a doctor. If necessary, it is additionally recommended to study the reviews of buyers who took the Finnish drug.

Video about the active substance Burana

Malysheva about ibuprofen: