Actovegin tablets. Price, reviews, analogues, instructions for use

Actovegin is a pill which are used in the treatment of neurological disorders. The tool has a high cost, however, it has most positive reviews and several cheaper analogues.

Release form

The medicinal product is produced in Russia in the form of tablets intended for systemic use. They are round, yellowish-green in color.

The product is contained in darkened glass bottles and packed in cardboard boxes.

Chemical composition

The active ingredient is deproteinized hemoderivat prepared from the blood of calves.

Additional composition:

• MCC;
• povidone K90 and K30;
• magnesium stearate;
• acacia gum;
• phthalic acid ester;
• talc;
• ozokerite;
• hypromellose phthalate;
• coloring matter;
• food additive E171;
• cane sugar;
• macrogol-6000.

All components combine well with each other and complement each other's action.

Pharmacological properties

The drug belongs to the group of stimulants that regenerate damaged tissues. At the same time, it improves trophism and normalizes metabolic processes.

The drug has an antihypoxic effect and has pronounced metabolic, neuroprotective and microcirculatory properties.

The action of the medication is aimed at the absorption and removal of oxygen. It also has an effect on improving glucose transport and excretion. This reduces the risk of ischemia and increases metabolic reactions in cells.

The drug blocks the programmed processes of cell death and reduces the risks of developing inflammatory processes in the nervous system (central and peripheral).

The drug promotes the detection and repair of damaged cells in the chain structures of DNA and suppresses the action of the enzyme responsible for premature cell death. This, in turn, leads to an improvement in the functioning and general condition of the nervous system. The medication has a positive effect on hematopoietic function and endothelium.

Thanks to its systematic reception, the development of the following effects is noted:

• increased capillary blood flow rate;
• reduction of the pericapillary area;
• a decrease in the tone of the sphincter and arterioles located in the pericapillary area;
• decreased blood flow in problem areas;
• improving the function of the enzyme responsible for the synthesis and, as a result, the restoration of the microvasculature.

Thanks to the studies carried out, it was possible to establish that the action of the drug occurs after about half an hour after its use. The maximum pronounced effect is observed after 3-6 hours after taking the drug inside.

Pharmacodynamics and pharmacokinetics

It is not possible to study the pharmacodynamic and pharmacokinetic properties of the drug, since its active substance is a physiological component present in the body person.

Indications for use

Actovegin - tablets (price, reviews, analogues of the drug are discussed in the article for informational purposes), which are used as part of complex treatment. The remedy has several recommendations for prescription related to neurological and vascular disorders.

Indications:

• impairment of cognitive functions, including disorders due to previous stroke or dementia;
• disruptions in peripheral circulation, as well as complications caused by this violation;
• polyneuropathy (diabetic form of the disease).

The medication should be used only after all examinations and diagnosis has been made.

Contraindications

The drug should be taken only in the absence of certain disorders and conditions.

Contraindications:

• intolerance to the components;
• allergy to fructose, sucrase / isomaltase deficiency, glucose-galactose malayusorption syndrome;
• minor age of the patient.

With extreme caution and only with the permission of a doctor, tablets can be used during pregnancy and during breastfeeding.

Before starting treatment, it is necessary to make sure that the patient is not allergic to the components. This requires a special diagnosis or a single dose of medication.

If any undesirable effects develop after taking 1 tablet, therapy should be interrupted and a specialist should be consulted.

At what age can the drug be used?

The medication is not intended for use in children and adolescents. The minimum age limit is over 18 years old.

Instructions for use, dosage

Actovegin - tablets (price, reviews, drug analogues may differ slightly from each other), which are intended for systemic use. Eat them just before eating.

• On the 5-7th day after the onset of ischemic stroke (acute phase), 2 g of solution is prescribed intravenously, after which they switch to tablets. Dosages: 2 tablets 3 times a day (no more than 1.2 g). Duration of admission is six months.
• With the development of dementia, 2 capsules are prescribed 3 times a day (1.2 g). The duration of the course is 20 weeks.
• Dosages for failures in the hematopoietic system: 1-2 pcs. 3 times a day (0.6-1.2 g). The duration of therapy is from 1 to 1.5 months.
• Patients with polyneuropathy in the first days are prescribed intravenous administration of the drug. Then they switch to a tablet form. Dosages: 3 capsules 3 times a day (1.8 g). Duration of admission is from 4 to 5 months.

Side effects

Adverse manifestations occur in extremely rare cases. Moreover, their development depends on the effect of the active substance on the human body or its physiological characteristics.

Side effects:

• allergy - shock conditions, fever caused by taking medications;
• skin manifestations - urticaria, a sharp development of hyperemia.

With the development of the listed signs or other reactions caused by taking the drug, it is recommended to stop further therapy and consult a doctor.

Overdose

According to clinical data, the drug does not have a toxic effect on the body, even in cases of exceeding the established dosages by 30-40 times.

To date, no cases of overdose have been recorded.

However, if the prescribed doses are significantly exceeded and any negative symptoms occur, you should immediately contact a medical institution for advice.

special instructions

It is not recommended to use the drug in pediatric practice. During pregnancy, the medication is prescribed only in cases where the expected benefit significantly outweighs the potential danger. The effect of the drug on the ability to drive a car or carry out other work requiring the speed of psychomotor functions has not been established.

Drug interactions

There is no information on drug interactions between tablets and other medications. However, when using other medical devices, it is recommended that you inform your doctor in advance.

Analogs

Actovegin tablets, if necessary, can be replaced with agents similar in action. Analogues are prescribed when the main agent is poorly tolerated. When choosing a substitute, the physiological characteristics of the patient and the form of the established disorder should be taken into account.

At the same time, the cost of the original product is not a determining indicator for its purpose. If necessary, you can preliminarily familiarize yourself with patient reviews on taking a particular medication. The choice of a generic drug should only be dealt with by the attending physician who is familiar with the characteristics of the patient's disease.

Tanakan (France)

This drug is available as a tablet or oral solution. The active ingredient of the product is Ginkgo biloba leaf extract. The drug belongs to the group of phytopreparations with a pronounced angioprotective effect.

It is used for the following conditions and disorders:

• cognitive and neurosensory dysfunction of various origins;
• damage to the arteries of the legs (lameness);
• hearing impairment and dizziness. Having a vascular origin;
• Raynaud's syndrome.

Dosages: 40 mg 3 times a day (1 tablet or 1 ml of solution). Take the remedy when eating. The solution must first be diluted in ½ tbsp. water. When taking the solution, it is recommended to use a special dispenser in the form of a pipette. The duration of therapy is at least 3 months. Further admission should be agreed with a specialist.

The drug has the following contraindications:

• allergy to components;
• gastritis, accompanied by the formation of erosion (exacerbation stage);
• blood clotting disorders;
• myocardial infarction;
• disorders of cerebral circulation, occurring in an acute form;
• the presence of ulcers in the stomach and duodenum;
• lack of lactase, allergy to lactose, glucose-galactose malabsorption (only for tablets);
• the minor age of the patient;
• carrying a child;
• lactation period.

Since the solution contains alcohol-containing components, it is recommended to use it extremely carefully and only under the guidance of a specialist under the following conditions:

• alcoholism;
• liver disease;
• TBI;
• pathology of the brain.

The dispensing system is over-the-counter. Cost - 450-570 rubles. depending on the dispensed dosage form and dosage.

Noben (Russia)

Actovegin - tablets (price, reviews, drug analogues, if necessary, it is recommended to clarify before starting therapy), which should not be used simultaneously with similar drugs. This substitute comes in the form of idebenone-based capsules.

It belongs to the group of nootropic drugs and is used for the following pathologies:

• cognitive and behavioral disorders caused by vascular disease or degenerative changes in the brain;
• cerebrovascular disorders and age-related changes in the brain, which led to the development of cognitive and behavioral dysfunctions.

Application features: the medicine is taken after eating, 1 capsule 2 to 3 times a day. The duration of treatment is individual, according to the indications of the attending physician.

Restrictions on taking the drug:

• hypersensitivity (allergy to any of the components);
• the minor age of the patient;
• chronic renal failure;
• lack of lactase, hypersensitivity to lactose, glucose-galactose malabsorption.

With extreme caution and only under the supervision of a specialist, the medication can be used under the following conditions:

• simultaneous use with anticoagulants;
• hemorrhagic stroke.

During pregnancy, as well as during breastfeeding, capsules are prescribed in cases where the potential danger is lower than the expected benefit.

The remedy has numerous side reactions, which you should familiarize yourself with or ask your doctor. If the patient has a high predisposition to the development of reactions of intolerance, it is necessary to choose another means of treatment.

If the color of urine changes during the use of the medication, its further use should be discontinued and a specialist should be consulted. Sales mode - by prescription. Price - 490-555 rubles.

Mexidol (Russia)

Actovegin - tablets (price, reviews, analogues of the drug are indicated by popularity, starting from the very demanded funds), which must be used by prior agreement with a specialist. This medicine is produced in the form of tablets for systemic use. Ethylmethylhydroxypyridine succinate acts as an active ingredient.

The drug belongs to the class of antioxidant drugs and is prescribed in the treatment of the following diseases and disorders:

• complications caused by impaired cerebral circulation;
• TBI (mild forms), including the consequences after them;
• withdrawal symptoms provoked by the use of alcoholic beverages (against the background of the development of neurosis-like vegetative-vascular disorders);
• encephalopathy with various factors of occurrence;
• VSD (vegetative-vascular dystonia);
• cognitive dysfunction caused by the presence of atherosclerotic deposits;
• ischemic disorders (complex treatment);
• anxiety states caused by neurotic or neurosis-like pathologies;
• asthenic syndrome;
• rehabilitation after toxic damage to the body caused by taking antipsychotic drugs;
• stressful situations that lead to the development of various disorders in behavior and cognitive functions.

Dosage regimen: 1-2 tablets 1-2 times a day, depending on the diagnosis. In case of withdrawal symptoms, treatment is carried out within 5-7 days. In other cases, the duration of therapy can vary from 2 weeks to 1.5 months. In severe conditions and ischemic disorders, the duration of the course can be up to 2 months.

Contraindications:

• hypersensitivity to the medication;
• functional disorders of the kidneys and liver, proceeding in severe form;
• lack of lactase, hypersensitivity to lactose, glucose-galactose malabsorption;
• children and adolescence;
• pregnancy;
• lactation period.

Terms of sale - prescription.

Cost - from 220 to 300 rubles.

Terms, conditions of sale and storage

• The tablets should be stored in a dark and dry place at temperatures up to 25 ⁰C.
• Expiration date - 3 years from the date of issue.
• Do not use after the expiry date stated on the package.
• Dispensing method - over-the-counter.

Price

Prices for pills may vary slightly depending on the region of sale and the pharmacy trade network.

Region / region	Dosage form / dosage	Price
Moscow, Moscow region	Tablets, 200 mg, 50 pcs.	RUB 1395-1555
St. Petersburg	RUB 1350-1480
Saint Petersburg (suburbs)	RUB 1410-1600
Leningrad region	RUB 1450-1590
Novgorod region	RUB 1485-1540

Before using Actovegin or its substitutes, it is necessary to read the instructions for their use and consult a doctor. Additionally, it is recommended to study the reviews of patients who took the pills. You can clarify the availability of funds, as well as find out its cost, at any nearby pharmacy located at the place of residence.