Afobazol (Aphobazolum). How to take for an adult, instructions, analogs are cheaper, what helps, composition, doctors' reviews, prices

Afabazole is one of the medicines that is used to normalize the psycho-emotional state the patient. The drug is recommended to be taken by an adult in order to eliminate anxiety, causeless fear and other manifestations. The medication is effective, but it is recommended to start taking it after examination and identification of the cause of the disorder.

Forms of release and composition of the drug Afobazol

The drug is produced by a Russian pharmaceutical company only in the form of oral tablets of small size and white color. They are packaged in blisters of 30 pieces. The cardboard box contains instructions explaining the rules for using the medicine, as well as 2 plates with pills.

You can also find a product packaged in small plastic bottles of 50 or 100 pieces. The substance afobazole or morpholine ethylthioethoxybenzimidazole acts as the main active ingredient, due to which the therapeutic effect is carried out. Its dose in a tablet is 5 or 10 mg.

Present in tablets and auxiliary ingredients:

• microcrystalline cellulose;
• potato starch;
• lactose;
• magnesium stearate;
• povidone.

The auxiliary ingredients have no therapeutic properties. The tablets are odorless, but rather unpleasant in taste.

Pharmacological properties

Afobazole can be taken by an adult for various emotional disorders, since it has sedative properties. The drug can be classified as an anxiolytic drug, and its active substance is a derivative of a non-benzodiazepine tranquilizer.

This means that the drug is not addictive, but is quite effective in the treatment of untreated forms of the nervous disorder.

The drug has the ability to affect certain centers in the brain that are responsible for sleep, motor skills and some other reactions. At the same time, benzodiazepine receptors are not stimulated, which is an advantage in the treatment of various disorders.

The drug has a mild hypnotic effect, and also protects nerve cells from the negative effects of external and internal factors.

As a result, the transmission of nerve impulses is normalized, irritability is reduced, and anxiety is eliminated. Additionally, the medicine helps to eliminate the somatic symptoms of the autonomic nervous system that occur during prolonged nervous tension.

Another property of the drug is the ability not only to eliminate anxiety, but also not to suppress the patient, that is, not to provoke constant drowsiness and apathy. As a result, there is a significant improvement in the condition without pronounced negative reactions.

Pharmacodynamics and pharmacokinetics

The drug, after ingestion, begins to act rather quickly. The active ingredient penetrates into nerve tissues and acts on the sigma receptors in the brain.

These receptors are located primarily in areas responsible for memory, emotional and sensory perception. In addition, they regulate fine motor skills, which explains limb tremors and other phenomena that occur during periods of severe anxiety.

When the medicine is taken, the transmission of impulses in these zones is normalized, which leads to an alleviation of the condition, as well as the elimination of internal and external manifestations.

Additionally, the active ingredient normalizes sleep, reduces the time required for the body to fully relax. As a result, the patient falls asleep faster, during the night he wakes up less often, his dreams are calm and do not provoke a new attack of anxiety.

In addition, the active substance of the agent does not have a negative effect on the patient's condition and does not slow down mental reactions. This allows you to use it for a long time without the risk of complications.

It is worth noting that the dual action of the drug makes it effective, since the sedative effect develops against the background of a slight stimulation of the emotional state.

The drug eliminates suspiciousness, uncertainty, and also prevents a sharp and unreasonable change in the patient's mood, which is observed when the psychoemotional balance is disturbed. In combination with normalization of sleep, recovery occurs, and the risk of relapse is also reduced.

After penetration into the digestive tract, the main ingredient of the drug is quickly absorbed and enters the patient's bloodstream, binds well to plasma proteins. The bioavailability of the drug is high, which explains its effectiveness. The active substance is rapidly processed in the body and within 3-6 hours is completely evacuated in the form of metabolites.

Food intake slows down the absorption somewhat. Patients with various diseases of the digestive tract and kidneys may notice that the therapeutic effect occurs somewhat later, but this does not reduce the effectiveness of the drug.

Rapid evacuation of metabolites from the body reduces the risk of overdose. The components also do not accumulate in tissues, blood, which is also considered an advantage, especially with prolonged use of the drug.

Indications for use

Afobazol is recommended to be taken only under strict indications, which reduces the risk of complications.

An adult medication is prescribed in the following cases:

• sleep disorders of various origins;
• nervous disorders of mild and neglected forms, accompanied by fear, sudden changes in mood and impaired coordination;
• neuroses associated with serious somatic diseases, for example, with oncological, cardiovascular, dermatological disorders of the chronic form;
• anxiety and insomnia in severe hypertension;
• vegetative-vascular dystonia, in which not only the internal organs suffer, but also the psychoemotional state. In this case, the patient has depression or increased excitability, mood changes often and suddenly, sleep worsens;
• premenstrual syndrome in women of different ages;
• withdrawal symptoms in patients with chronic alcoholism;
• discomfort arising in patients with refusal from cigarettes.

The drug can be used as the main method of therapy or as part of a complex treatment.

Contraindications

The drug is not prescribed to patients with intolerance to its main substance, as well as a tendency to allergic manifestations. It is not used in the treatment of patients during breastfeeding and carrying a child.

In addition, contraindications include lactose intolerance, when taking pills, the risk of complications increases. Severe hepatic and renal failure is considered a reason for refusal to use.

In case of internal bleeding, acute gastric ulcer, the drug is not used. The severe course of coronary heart disease, as well as the acute period of stroke, are contraindications.

At what age can the drug be used?

Afobazole can be taken by an adult in the absence of contraindications. However, the drug is not prescribed for patients under 18 years of age, since side reactions from the internal organs may develop. In each case, the doctor decides on the prescription of the medication.

Instructions for use, dosage

Tableted medication is prescribed for oral use only. It is allowed to take pills immediately after meals or after 2-3 hours, which does not impair the effectiveness. The daily dosage of the drug is determined individually, taking into account the degree of neglect of the condition.

For mild sleep disorders, 1 tablet is prescribed at bedtime. The medicine should be taken for 10 to 14 days. As a rule, the therapeutic effect appears after 5-7 days, and the course is sufficient to normalize the condition.

If necessary, a single dosage is doubled, which allows you to achieve the maximum therapeutic result. In addition, a longer use is possible if the condition does not normalize for 10-14 days.

In severe forms of a nervous disorder associated with various reasons, the course of therapy lasts at least 2 weeks. In this case, the patient takes 1 tablet 2 times a day. If the disorder is associated with autonomic disorders, the daily dosage can be increased to 30 mg, that is, the patient needs to take 1 tablet 3 times a day for 2-3 weeks.

Hypertension, accompanied by anxiety, headaches and unreasonable fear, is treated in a comprehensive manner. The therapy regimen includes Afobazol, which should be taken 2 tablets per day. The course lasts up to 3 weeks.

There are cases when it is necessary to double the daily rate to 6 tablets, and extend the course to 2-3 months. However, the decision is made by the doctor after examination and finding that there is no effect from taking the pills.

Side effects

Afobazole should be taken by an adult with caution, since the drug often leads to negative reactions. They can be observed if all the rules are observed or if they are violated.

Organs and systems	Frequent negative reactions
Nervous system	Headache is considered the most common complication of medication. It can be associated with various reasons and usually does not require specific treatment. Symptoms disappear after drug withdrawal or daily dosage reduction. Some patients report dizziness, lethargy, and drowsiness.
Musculoskeletal system	Muscle and joint pain is considered a rare side effect of medication use. Usually, the symptom is associated with damage to nerve endings and a violation of the impulse to the tissues. No special treatment is required to eliminate the symptom, the condition returns to normal a few days after the pills are discontinued.
Vessels and heart	Arrhythmia and tachycardia with prolonged use of the drug manifests itself quite often. However, the agent has almost no effect on blood pressure indicators, but in patients with hypertension, they decrease slightly, which is associated with a sedative effect and normalization of sleep. When taking an excessive dose of the drug, the side reaction may be more pronounced.
Digestive tract	With prolonged treatment and taking pills on an empty stomach, there is pain in the epigastric region, nausea, and digestion is disturbed. In many patients, there is a disorder of stool, manifested in the form of constipation or diarrhea.
Leather	An allergic reaction to a medication manifests itself in the form of rhinitis and conjunctivitis, which is aggravated if left untreated. In addition, rashes, itching of the skin and flaking areas may occur.

Adverse reactions are considered a reason to discontinue the drug and visit a doctor.

Overdose

Despite the rather rapid elimination of the active substance from the body, cases of drug overdose have been recorded. Experts note an increase in the sedative effect, which leads to the development of lethargy and indifference to surrounding events. The patient cannot clearly answer the questions posed, his speech is indistinct, confused.

Many patients with an overdose spend most of the day in a horizontal position, refuse food. Only in some cases, taking a large dose of the drug leads to a clouding of consciousness, the development of a delusional state.

In addition, an overdose is often accompanied by symptoms of intoxication, manifested in the form of severe headache, nausea, and vomiting. In this case, gastric emptying leads only to a short-term improvement, after which there is repeated vomiting.

If an overdose develops an allergy, it can turn into acute urticaria, in which the appearance of a rash is accompanied by severe itching of the skin and nervous disorders. In any case, the condition requires immediate discontinuation of the pills and a visit to the doctor for symptomatic treatment.

special instructions

Afobazol is recommended for an adult only after a preliminary examination and identification of the cause of the symptoms. Otherwise, the condition may deteriorate. If the patient does not feel any improvement during the first 2 weeks, or if the symptoms worsen, it is necessary to see a doctor. Cancellation of pills may be required.

It should be noted that the medicine does not affect the ability to drive vehicles, therefore, during the period of treatment, the patient is allowed to drive a car or operate various production technique.

Drug interactions

The medication is allowed to be used simultaneously with antibiotics, pain relievers and anti-inflammatory drugs. There are no negative reactions when taking vascular, antihypertensive, antiarrhythmic drugs in combination with Afobazole.

However, it is worth remembering that the remedy enhances the effect of some hypnotics and antiepileptic drugs, so it is worth warning the doctor if the patient is taking such medications.

There is a lack of negative reactions when taking Afobazol and hormonal agents. It does not enhance or weaken the effect of drugs used for general anesthesia.

Analogs

Some patients need treatment for nervous disorders, but for some reason cannot take Afobazol. In this case, you need to find a suitable substitute with a similar composition and therapeutic properties.

The most popular analogues:

• Tenoten - homeopathic medicine based on natural ingredients, available in tablet form. The drug cannot become a full-fledged substitute for Afobazole, but as a mild sedative it helps to cope with anxiety and improves concentration. Tablets should be taken 1 piece 2-3 times a day for 4 weeks.
• Grandaxin - a sedative that helps to eliminate anxiety, insomnia and other manifestations. The remedy is considered effective, it is prescribed in short and long courses, depending on the severity of the symptoms. The drug is available in oral tablet form.
• Novo-passite - a herbal remedy that also contains a synthetic component. It has pronounced sedative, mild hypnotic and anti-anxiety properties. The drug can be purchased in the form of oral drops or tablets. The dosage and duration of use is determined individually, taking into account the disease and the degree of its neglect.

Any of the medicines is prescribed by a specialist according to strict indications; self-administration can provoke complications.

Terms, conditions of sale and storage

You can buy a medication at a pharmacy without a prescription from a doctor, which increases the risk of complications when used alone.

The maximum storage time is 2 years. The production date can be seen on the packaging. Taking pills after the expiration date is strictly prohibited. Store the medicine in a cool and dry place, limiting the access of children and sunlight.

Price

The cost of the drug in different pharmacies ranges from 250-400 rubles. depending on the number of tablets in the package.

Afobazole is a fairly effective and relatively safe medicine that can be taken for various nervous disorders. For an adult, a medication is prescribed as the main or auxiliary in order to eliminate the most pronounced manifestations that worsen the condition and work of internal organs.

Video about the drug Afobazol

Afobazol - application, analogues, price: