Maxitrol (Maxitrol) eye drops. Price, instructions for use, cheap analogs, reviews

Maxitrol - effective combined eye drops, which are used in the treatment of various pathologies of the visual apparatus. The price of the drug is quite high, but it is justified by the effectiveness and unique properties of the drops. Before starting the therapeutic course, a preliminary examination and consultation with a specialist are recommended, which will avoid complications.

Forms of release and composition of the drug

The medication can be purchased in the form of eye drops. The liquid is transparent and colorless, has a specific odor. Drops are packaged in 5 ml polyethylene bottles equipped with a dropper. Each bottle is placed in an individual cardboard box, where you can also find instructions explaining the rules for using the drug.

The composition of the medication contains several main components, the combination of which makes it possible to exert a pronounced therapeutic effect on the ocular apparatus. The main substance is dexamethasone, the amount of which in 1 ml of drops is 1 mg. In addition, the action of the hormonal component is enhanced by neomycin and polymyxin B.

There are also excipients in the composition:

• Polysorbate.
• The additives are neutral.
• Cellulose.
• Distilled water.
• Benzalkonium chloride.

Additional ingredients do not have a therapeutic effect, they are necessary to preserve the composition of the drug.

Pharmacological properties

Maxitrol eye drops, the price of which may differ depending on the region of distribution, have pronounced anti-inflammatory and antibacterial properties.

The antibiotic contained in the composition helps to destroy pathogens, and hormonal the substance stimulates tissue repair and relieves inflammation, even with an advanced course diseases.

Additionally, the drug removes tissue edema, eliminates redness of the eyeball and prevents the growth of pathogenic bacteria on the cornea. As a result, the healing process is accelerated and the risk of the pathology spreading to other tissues outside the visual apparatus is significantly reduced.

The presence of polymyxin B in the composition helps to cope with such microorganisms that are not sensitive to neomycin. As a result, even very resistant bacteria are destroyed. Due to the presence of a hormonal component, the effect of antibacterial substances is enhanced, which leads to a significant improvement after the first applications.

Pharmacodynamics and pharmacokinetics

The drug begins to act immediately after it enters the cornea or the conjunctival sac. The active substances gradually spread to the affected tissues, after which they begin to act separately.

Dexamethasone helps to stop the inflammatory process, and also stimulates the restoration of the tissues of the eye apparatus. Even in the event of complications, the substance helps to significantly improve the patient's condition and prevents further progression of the disease.

Additionally, the drug has an anti-allergic effect, relieves itching and swelling of the eyelid skin, if the pathology is accompanied by similar manifestations.

In addition, dexamethasone improves the condition of the cornea and increases its resistance to various external stimuli, bacteria and viruses. The action of the antibacterial component of neomycin is significantly reinforced by the presence of hormonal component, therefore the risk of complications in infectious lesions of the eyeball is significantly decreases.

Neomycin has bactericidal properties, effectively destroys various microorganisms. The activity of the component against Staphylococcus aureus, streptococci and Pseudomonas aeruginosa was noted.

The substance destroys the causative agents of diphtheria, Klebsiella, as well as gram-negative and gram-positive bacilli. Thanks to such a wide spectrum of antibacterial activity, it is possible to treat the most common and dangerous pathologies of the visual apparatus.

Polymyxin B also belongs to the group of antibacterial components. Neomycin has a bactericidal effect, that is, it disrupts the metabolism in pathogenic bacteria. Which leads to their death. However, the action of polymyxin B is aimed at blocking the permeability of the membranes of pathogenic microorganisms.

It acts on Klebsiella, Pseudomonas aeruginosa, Escherichia coli. The substance is noted to be active against some dangerous rod-shaped bacteria.

The complex action of the active ingredients leads to a quick cure of the patient with mild the form of the disease and a significant acceleration of recovery in the advanced course of the pathological process.

With local application of the drug, there is a slight absorption into the systemic circulation. It is almost impossible to detect drug components in the blood, which reduces the risk of overdose and other complications.

The active substances are almost completely localized precisely in the area of ​​application, that is, in the tissues of the eyeball and on the cornea. It is due to this that a pronounced therapeutic effect is carried out.

Experts note the absence of a cumulative effect, that is, the components do not accumulate in the tissues, therefore, after the termination of the course of treatment, their residues are removed using the lacrimal apparatus.

The ingredients of the drug do not pass into breast milk and do not penetrate the placental barrier. The assimilation of the drug does not depend on the condition of the digestive tract, as well as the patient's urinary system.

Even in patients with chronic severe disorders of the stomach, kidneys, intestines, there is no decrease in the effectiveness of the medication.

Indications for use

Maxitrol is used only under strict indications and after examination. Eye drops have a pronounced effect, so their price is justified.

The main indications for the appointment of a medication:

• Blepharitis of varying severity, when the condition of the mucous membrane of the eyelids worsens significantly.
• Conjunctivitis of allergic, inflammatory or infectious origin. In this case, the medicine can be used not only in the case of an acute course of the disease. But even when it goes into a chronic form.
• Keratoconjunctivitis in acute and advanced form in patients of different ages.
• Keratitis, in which a patient's vision deteriorates as a result of the development of an inflammatory process.
• Iridocyclitis in acute and chronic form. The tool can be used in the presence of complications or an advanced course of the disease.

Additionally, the drug can be prescribed as a means of preventing complications in the postoperative period. This application is most often practiced for the treatment of elderly patients after lens replacement or other interventions. Its useful to note. That the drops are equally effective when performing a major operation or when using a minimally invasive technique.

Contraindications

An effective medication is not always allowed to be used, especially without first consulting a doctor. Contraindications include intolerance to the components of the composition and a tendency to allergic manifestations, in which complications arise after using medications from different groups.

The remedy is contraindicated in the diagnosis of chickenpox, as well as eye diseases caused by viruses.

Do not prescribe drops when detecting purulent inflammation of the eye, provoked by microorganisms that are not sensitive to the active antibacterial components of the composition. In addition, the medicine is contraindicated for various fungal pathologies affecting the eyeball.

It should be noted that the medication is not effective in identifying extensive mycotic lesions of the visual apparatus., since its active ingredients are not capable of destroying such microorganisms.

After removing a foreign body from the cornea of ​​the eye, the use of drops is contraindicated. Only after tissue repair is it allowed to use the medication. In case of damage to the eyes with a tubercle bacillus, the drug is not prescribed, since its active ingredients are not able to destroy the microorganism, but can provoke a worsening of the course of the disease.

The use of the drug for shingles is categorically contraindicated. In this case, the degree of neglect of the disease does not matter.

With extreme caution, the drug is prescribed to patients with diagnosed glaucoma and cataracts. For elderly patients, drops are also prescribed with caution and only after a preliminary examination. This approach allows you to avoid complications or significantly reduce the likelihood of their occurrence.

Relative contraindications include the severe course of epilepsy and heart failure, as well as the recovery period after surgery on the organs of the rye cavity. In this case, the doctor makes the decision on the prescription of the medicine individually in each case.

At what age can the drug be used

Maxitrol eye drops, the price of which may differ slightly in different pharmacies, are prescribed only to patients over 18 years of age. This is due to the lack of data on the effect of drops on the eyeballs of children and adolescents. In exceptional cases, a medication can be prescribed to a child, but only on strict indications and under the supervision of a specialist.

Instructions for use, dosage

The scheme of use and dosage of the drug is determined taking into account the degree of neglect of the disease and associated complications that can aggravate clinical manifestations. As a rule, 2 schemes are used - for light and severe course of the pathological process.

The course of the disease	Scheme of the use of drops, dosage
Mild infectious or inflammatory disease	At the initial stage or mild course of the pathological process, adults are prescribed 2 drops of the drug in each or only in the affected eye. The procedure should be carried out 4-5 times a day, depending on the disease and the rate of its progression. The duration of the therapeutic course is 7-10 days. In each case, the duration of use may vary depending on the individual characteristics of the organism.
Severe pathology with an increased risk of complications	With a running inflammatory or infectious process, 1-2 drops are administered to the patient every hour during the day. This scheme can be used from 2 to 5 days, depending on the disease. After that, the patient receives 1 drop of the drug every 3 hours for 5-7 days. As a rule, this period is sufficient to achieve a therapeutic result and prevent complications.

When using drops, it is important to follow the rules that prevent complications. It is important to wash your hands with soap and water before instilling an eye. During the procedure, the drop should fall into the conjunctival sac, which, after closing the eye, will allow the medicinal solution to be distributed over its entire area.

When carrying out manipulations on your own, it is very difficult to trace the degree of approach of the dropper to the eye, which increases the risk of attachment of the tip to the cornea. This can lead not only to its damage, but also increases the risk of reproduction of pathogens on the surface.

That is why it is better to entrust the instillation procedure to a specialist or a relative. If complications arise during the manipulation, it is worth interrupting it and consulting a doctor.

Side effects

Maxitrol eye drops, the price of which is quite high, rarely provoke general adverse reactions, which is associated with minimal absorption of the components of the composition into the systemic circulation. Despite this, patients may develop complications. They usually affect the visual apparatus, but can provoke a deterioration in the general condition.

An allergic reaction to the drug manifests itself in the form of redness of the eyeballs, as well as the skin around the eyes. Puffiness of the eyelids is considered a common symptom of allergies. In this case, the patient has severe itching, burning and peeling of the skin.

As the condition progresses, a rash appears around the eyes, as well as on the face. In this case, the rash can spread to the hands, as they come into contact with the affected area when scratching.

The skin on the face, especially around the eyes, is very sensitive and thin, therefore, scratching the affected area leads to severe irritation. As a result, the outer layer is damaged, a weeping painful surface is formed.

Gradually, it becomes covered with a crust. Only after the independent discharge of the crusts and in the absence of their mechanical damage at the site of irritation, the skin is restored.

It is worth noting that such negative reactions are less common. In addition, allergies can provoke a deterioration in the general condition. The patient speaks of weakness and rapid fatigability, as well as decreased performance. Allergies can trigger headaches, dizziness, and sleep disturbances.

Additionally, intolerance to the composition can provoke allergic rhinitis. In this case, the patient has edema of the mucous membrane of the nasal sinuses, but a large amount of transparent liquid mucus is released from the nose.

With the progression of the condition, the patient cannot breathe air through the nose, which leads to an increase headache and deterioration in concentration as a result of insufficient oxygen supply to tissues.

With prolonged independent use of the drug, areas of ulceration may appear on the cornea, which are formed as a result of exposure to the tissues of corticosteroids.

Sometimes complications manifest themselves in the form of the development of fungal lesions of the cornea, which occurs against the background of exposure to antibacterial components. In this case, the use of antifungal drugs is required to eliminate the manifestations.

If negative reactions occur, it is recommended to stop using the drops. Symptoms usually disappear within a few hours. However, if the manifestations persist or worsen, it is worth visiting a doctor who will prescribe medications to normalize the condition.

Overdose

To date, no cases of drug overdose have been recorded, since it is used topically and penetrates into the systemic circulation in a minimal amount. However, experts do not exclude this possibility if the patient has a tendency to allergic manifestations.

In case of an overdose, the symptoms of allergy are aggravated, the itching intensifies, and there is a strong swelling of the eyelids. The patient is unable to fully open his eyes, the swelling spreads to the face. In addition, foci of redness appear on the skin. The symptoms of allergic rhinitis are also aggravated, leading to increased headaches and sleep disturbances.

Overdose usually does not threaten the patient's life, and its symptoms gradually disappear after stopping the use of drops. However, if the condition worsens, the help of a doctor is required. In a hospital setting, a specialist usually prescribes systemic medications that eliminate the manifestations of an overdose.

special instructions

Maxitrol eye drops, the price of which corresponds to high quality, is important to use only after a preliminary examination and in the absence of contraindications. It is prohibited to prescribe medication on your own. You can not increase the dosage without a doctor's prescription, and also prolong the course prescribed by a specialist.

When instilling drops, it is better to take a comfortable position, for example, lying with the body raised or sitting with your head tilted back. This will allow the drops to be maximally distributed over the cornea, while providing a therapeutic effect.

When using the medicine for more than 10 days in a row, it is necessary to measure the intraocular pressure in the patient, since there is a risk of a significant increase. That is why the drug and its dosage are prescribed only by a doctor.

Drug interactions

There is no negative effect of the drug in combination with other medicines. However, you should not bury the solution at the same time as other antibacterial and hormonal agents. This can lead to complications and aggravation of the course of the underlying disease.

If it is necessary to use other eye drops, it is necessary to maintain an interval between the use of different medicines. The minimum interval is 15 minutes. This will eliminate complications.

Analogs

In some cases, the combined medication cannot be used.

In this case, the doctor selects a suitable substitute with similar medicinal properties:

• Dexa-Gentamicin - popular and effective eye drops that have anti-inflammatory, antibacterial and antiseptic effects due to the content of dexamethasone and gentatsmicin in the composition. The medicine is prescribed to adults for various inflammatory and infectious pathologies.
• Tobradex - another popular and very effective eye drops. They have pronounced anti-inflammatory and antibacterial properties, as they contain dexamethasone and tobramycin. The latter component has a wide spectrum of antimicrobial activity, which enhances the effect of the hormonal component.

Maxitrol has no structural analogs, the composition of which would be completely identical, but substitutes have similar properties, therefore, if necessary, they can replace the original medication. Despite this, it is prohibited to use them without a doctor's prescription.

Terms, conditions of sale and storage

You can buy medication at the pharmacy with a doctor's prescription. The maximum shelf life is 2 years. But after opening the bottle, the drops can be used for no more than 4 weeks. After that, they are unusable. It is necessary to store the medicine in a dark, cool place out of the reach of children.

Price

In different pharmacies and regions, the price of drops is different. On average, it is 450-700 rubles.

Maxitrol is a popular and effective eye drop that is used to treat many eye conditions in adults. The price of the medicine is quite justified, since they have unique properties and almost always help prevent complications.

Video about eye drops

How to properly instill eye drops: