Vasobral( Vasobral) is a combined medicinal product, the components of which are part of the dihydrated derivatives. Effective in cases of circulatory disorders in the brain.
The drug has a stimulating effect on the receptors of dopamine and serotonin, which are located in the structures of the central nervous system. With the use of the drug, the processes of gluing together platelets in the peripheral blood stream decrease, the permeability of the vascular wall decreases. Under the influence of the drug, the blood flow of the brain improves, the risk of hypoxic brain damage decreases.
Caffeine is part of the drug has a stimulating effect on mental activity and has an analeptic effect.
The mechanism of action of caffeine is associated with an exciting effect on the cerebral cortex, increases efficiency and mental activity, reduces drowsiness and relieves fatigue. Stimulating affects reflex centers in the spinal cord, stimulates the action of the respiratory center, increases daily diuresis.
Contents
- Chemical Composition
- Pharmacokinetic Properties
- Scope
- Use of the drug for osteochondrosis
- Migraine use
- Contraindications and limitations
- How to use and dosage regimen
- What are the symptoms of a drug overdose?
- Side effects
- Special instructions
- Interaction with drugs from other pharmaceutical groups
- Use with alcoholic beverages
- opinion
- opinion Disposal and storage conditions
Chemical composition
The drug is given in the form of tablets of 4 mg of active ingredient, 10 tablets in one plate and in vialsin the form of a solution of 2 and 50 ml.
One tablet of Vasobrala contains in its chemical composition alfadihydroergokryptin - 2 mg, caffeine - 20 mg. A similar chemical composition is contained in ampoules of 2 ml of drug solution in each.
Additional substances include citric acid, ethyl alcohol, purified water and glycerin.
Pharmacokinetic properties of
When the drug is administered orally, it is absorbed into the stomach in the bloodstream, the absorption process is accelerated by the ingestion of caffeine impurities by the .
After 30 minutes after taking the drug, its maximum concentration in the blood plasma is reached.
The substance is excreted by the kidneys after about 1-3 hours.
Two hours after taking the medication, its increased concentration in bile is fixed, a small amount of the drug can be contained in breast milk.
Scope of application
Indications for use The scope is quite wide and varied:
- reduced mental activity and memory;
- with reduced spatial orientation;
- age-related changes in brain tissue;
- attention violations;
- treatment of vegetovascular dystonia with cerebral vascular lesions;
- with traumatic brain and head injuries;
- infectious diseases of the central nervous system;
- for the prevention of the development of migraine attacks;
- Ménière's disease;
- impairment of visual function in diabetes mellitus;
- therapy of hypertension;
- for acute or chronic venous insufficiency of peripheral vessels.
Application of the drug for osteochondrosis
Reception Vazobrala with cervical osteochondrosis greatly improves blood flow through the spinal and cerebral arteries, a violation in the bloodstream which occurs due to compression of the altered vertebrae.
The use of the drug improves local microcirculation, improves memory and significantly reduces the risk of progression of symptomatic signs in osteochondrosis.
Migraine application
People with different ages are affected by migraine attacks. The use of the drug for migraine improves blood flow to the brain, stimulates the action of intellectual reserves, reduces blood pressure and cures headaches.
In such a disease, the drug is administered exclusively individually, depending on the severity and severity of the headache.
Contraindications and limitations
The use of medication is strictly prohibited in such cases:
- with individual drug intolerance;
- period of bearing the child;
- period of lactation.
How the drug drug affects the fetus during pregnancy to date is not fully known, but has been found to have small concentrations of metabolites in the breast milk.
That's why women during pregnancy and lactation use tablets and Vasobrala solution is not recommended.
It is known that a large concentration of metabolites after the breakdown of the components of the medicine accumulates in the bile ducts of the liver, and therefore the use of the drug by persons with acute or chronic hepatic insufficiency is unacceptable.
Method of administration and dosage regimen
Vasobrail is prescribed for 1 -3 tablets in two divided doses throughout the day, a solution of 1-2 ml can be used, which is recruited using a syringe or pipette.
The medicine is consumed while eating, while being washed down with water. The duration of the course of treatment is established by a qualified specialist, the dosage and duration of medication depends on the age of the organism and on the individual sensitivity to the components of the drug.
The average duration of the therapeutic course is approximately 1-2 months. If there is such a need, then the course of treatment is prolonged depending on the decision of the treating doctor.
What are the symptoms of a drug overdose?
If the drug is taken in large quantities than prescribed in the doctor's prescription, the risk of developing symptoms of an overdose increases. Symptomatic reactions with an overdose of Vasobrail manifested in the form of dyspeptic disorders, migraine attacks, allergic reactions, dizziness.
In case of development of one of the above symptomatic signs, it is necessary to urgently seek medical help. Antidote for overdose is Atropine in a dose of 1-2 mg subcutaneously.
Side effect of
When taking Vazobral, there are possible side effects on the part of the body in the form:
- of a sharp drop in blood pressure;
- of allergic manifestations in the form of rash, itching and flushing of skin;
- nausea and vomiting, soreness in the stomach and intestines, manifestations of flatulence;
- sensations of palpitation, tachycardia;
- attacks of migraine and dizziness, increased nervous excitability and nervousness.
The occurrence of adverse reactions when taking medication is rarely found in clinical practice.
Specific instructions
Vasobral is a drug that can affect systemic arterial blood circulation, the drug is able to rapidly reduce blood pressure in people with hypertensive crisis.
Since the drug contains caffeine in its composition, it can disrupt the sleep and wake cycle, and also causes tachycardia against a background of a sharp drop in blood pressure. It is necessary to exclude the taking of tablets and solution before a long automobile journey.
It is necessary to take medicine only during meals, it is strictly forbidden to use medicinal substance on an empty stomach.
Before a sporting event, medication should be discarded, as doping control in this case can be positive. It is forbidden to perform heavy and dangerous work together with taking the drug.
Interaction with medications from other pharmaceutical groups
Use of Vasobrail with drugs that lower blood pressure may contribute to hypotonic crisis, fainting and even lead to collapse.
Since the drug contains caffeine in its chemical composition, it is forbidden to use sleeping pills and sedatives, since they have the opposite pharmacological effect.
When used in conjunction with Levodopa, painful sensations develop in the epigastric region, there is a fever and a headache.
Use with alcoholic beverages
When taking medication, avoid drinking alcohol. Known is the fact that Vazobral has a stimulating effect on the central nervous system, and is also able to strengthen the mechanisms of action of drugs that are applied with it in the complex.
Since chronic alcoholics are constantly at risk of alcohol intoxication, joint intake of alcohol and Vasobrail can lead to increased side effects and the rapid development of intoxication symptoms.
There is an opinion of
Opinion of practicing doctors and reviews of patients who have undergone or undergoing Vazobral treatment.
Since Vasobral has appeared on the pharmacological market, I apply it for the treatment of vertigo and for violations of coordination of movements in people with impaired functions of the vestibular apparatus. For all time of application of adverse reactions it was not observed.
Ekaterina Sergeevna, neurologist 15 years of experience
I use the medication only in the treatment of patients undergoing in-patient care. Vazobral is also well suited for the treatment of venous insufficiency. Side effects when taking the drug has not been observed so far.
Olga Nikolaevna, neuropathologist 27 years of experience
With the advent of Vazobrala in medicine, we actively began to apply it in practice, and the medicine proved itself from the best side. In frequent cases, I prescribe the drug to elderly people suffering from dizziness, headaches, insomnia. The treatment is effective, I am satisfied with the results.
Neurologist, work experience 27 years
The drug is widely used in medical practice for treating people of different age categories. Judging by the analysis, the results exceeded our expectations.
Neurologist, 16 years work experience
Three months ago, I was diagnosed with myocardial infarction, my head ached terribly, my stomach ached, my blood pressure increased. The neurologist has appointed or nominated to me Vazobral, I apply a medicamental agent already during a month.
Almost from the very beginning of the treatment, I noticed that the headaches and dizziness disappeared. Thanks a lot to my doctor, the drug helped a lot.
Galina, 42 years old
For a long time I was tormented by migraine attacks, hypertension and hypersensitivity to a sharp change of weather.
Used various means, including traditional medicine. The neurologist advised me to use Vasobrail. As a result, after half a month after the start of taking the medication the headaches decreased, the general well-being improved, the sleep normalized.
Ekaterina, 45 years old
Tired of migraine, blood pressure jumps and therefore there were difficulties with the selection of a suitable medication. Buying dietary supplements, threw a lot of money to the wind, because the effect was not observed.
On the advice of friends I turned to the doctor - neurologist, who prescribed me Vasobral. With the beginning of taking the drug, headaches, insomnia was gone, an upbeat mood returned.
Catherine, 42 years old
From a painful headache neuropathologist prescribed Vazobral to me, as the drug dilates the vessels of the brain, thus relieving pain. Started taking a second course and the general state of the body improved significantly, memory became better, the noise in the ears disappeared.
Xenia, 38 years old
More than two years ago, I was diagnosed with CHEM( chronic cerebral ischemia), was suffering from headaches and the constantly depressed mood did not bother me. My attending physician said - you need to be treated, Vazobral prescribed and after a couple of days of therapy I felt relief, the pain decreased, and my tone improved.
Alla, 44 years
Release and storage conditions
Prescription from the treating doctor.
Price Vazobrala is:
- tablets, 30 pieces in one package, 800 -900 rubles;
- solution, 50 ml 400-500 rub.
Store medicament in a dry and cool place, without free access for children.
The drug is usable from the time it is manufactured, the expiration date should be indicated on the package or in the instructions for use.