Midokalm nyxes and pills - instructions for use

Meadocam is a drug that helps to remove the increased tone of skeletal muscles in arthrosis, osteochondrosisand other neurologic syndromes. There are many diseases associated with a pathological increase in muscle tone.

These conditions are accompanied by pain and circulatory disorders, which in turn leads to the appearance of edema and provokes more pronounced adverse changes in tissues and organs. To break this vicious circle and called for drugs, like Midokalma. They cope well with painful symptoms, have local anesthetic and muscle relaxant effect.

Muscle relaxants help to remove the pathological tension of the muscles, so that the pain recedes and the person can lead a habitual way of life. At the same time, it should be understood that such drugs do not solve the main problem, but only eliminate pain, therefore they are used as ancillary drugs in the complex therapy of the underlying disease.

Midokalm refers to muscle relaxants of central action. This drug affects the areas of the brain and the central nervous system, which are responsible for the regulation of muscle tone.

The exact mechanism of muscle relaxant effect is still unknown, but numerous studies have confirmed that the use of such medicines does not harm the cardiovascular system and other vital organs of man. Let us dwell in more detail on how correctly to use Midokalm, under what conditions it helps and what features it possesses.

Midokalm - the action of the drug

Midokalm is an effective and safe central muscle relaxant, intended for the treatment of neurological syndromes associated with trophic disorders, pain and increased skeletal muscle tone. The main active substance of the drug - tolperisone hydrochloride, has a local anesthetic effect and helps reduce hypertonicity and muscle rigidity.

Its action is carried out through the central nervous system. Suppressing the increased excitability of the spinal cord, it inhibits the transmission of pathological nerve impulses. Due to this, relaxation of muscles is achieved, puffiness is eliminated and painful sensations are removed. In addition to reducing musculoskeletal tension, the drug promotes vasodilation, improves blood circulation and lymph flow.

This effect provides the ability to perform active voluntary movements, the patient can move freely without feeling pain. Midokalm does not affect the cerebral cortex, which allows you to maintain a clear consciousness and a high level of wakefulness.

This distinguishes the drug from other drugs that cause lethargy and drowsiness. Numerous clinical studies of Midokalma confirmed the absence of adverse effects on the functions of the kidneys, the liver and the organs of hematopoiesis.

The drug is well absorbed from the digestive tract and reaches its maximum concentrations 30-60 minutes after ingestion. Metabolized in the liver and kidneys, is excreted from the body in the form of metabolites with urine.

Composition and Form of Release

Medication Medokalm is produced in two dosage forms:

1. Tablets( 50 mg and 150 mg)
2. Solution for injections in ampoules under the name Midokalm Richter

For oral administration Midokalm is released as round tablets enclosed in a film membrane. Biconvex, white tablets have a weak characteristic odor and a corresponding engraving. One tablet Midokalm 50 mg with an engraving "50", contains the main active substance Tolperisone in a volume of 50 mg, Midokalm 150 mg with an engraving "150" contains 150 mg Tolperisone, respectively.

In addition, the tablets contain auxiliary substances:

• Citric acid monohydrate
• Silicon dioxide
• Microcrystalline cellulose
• Talc
• Cornstarch
• Stearic acid
• Lactose

The preparation is produced in plastic blisters, each containing 10 tablets, blisters of 3 pieces packed in cardboard packs. Midokalm stored in a dark, dry place, inaccessible to children. The permissible temperature conditions are from 15 to 30 ° C.Shelf life of the drug is 3 years.

Midokalm for injection is released in dark ampoules containing 1 ml of solution. The injection solution is clear, colorless or with a slightly greenish tinge and a characteristic specific odor. One ampoule contains 100 mg of tolperisone hydrochloride + 2.5 mg of lidocaine. In the package with the drug there are 5 ampoules. Lidocaine, which is part of the drug, provides a local anesthetic effect.

Indications

Midokalm is widely used in medical practice for the treatment of various pathologies:

• In diseases of the musculoskeletal system accompanied by muscle spasms, hypertension of muscles and muscle contractures( cervical and lumbar osteochondrosis, spondylosis, arthrosis of large joints, intervertebral hernia, spondylarthrosis, lumbago)
• With organic CNS diseases accompanied by spasms of the transverse striated muscles and increased muscle tone( myelopathy, acute disorders of cerebral circulation, raceseyanny sclerosis, encephalomyelitis, pyramidal tract lesions)
• In pediatric drug used in the treatment of disease Little( spastic paralysis) and encephalopathies involving muscular dystonia. Little's disease is manifested in children's spastic paralysis of the hands and feet. Intellect of the child does not suffer at the same time. Miorelaxant helps relieve pathological tension and significantly improves the condition, therefore it is widely used by neurologists to treat such conditions.
• Midokalm is used as part of restorative treatment after traumatologic and orthopedic operations.
• The drug is prescribed to eliminate postthrombotic disorders of venous outflow and recovery of lymphodynamics.
• It is used in the treatment of trophic ulcers of the lower extremities, diabetic angiopathy, thrombangiitis obliterans.
• The combination therapy is prescribed for the treatment of autoimmune diseases: Raynaud's disease, systemic scleroderma, angiopathy of various genesis.
• Used to restore impaired vascular innervation in acrocyanosis, angioedema dysbasia.

Thus, Midokalm is widely used not only in the field of neurology, but also successfully used in pediatrics, traumatology, in the treatment of vascular disorders and autoimmune pathologies.

Instruction for use

The doctor selects the dosage of the preparation and the optimal treatment regimen individually, taking into account possible contraindications, the severity of the disease, the weight and age of the patient.

According to the instructions for use of Miodocalm, the dosage for adults is set at an initial volume of one tablet( 50 mg) 2 to 3 times a day. Then the dose gradually increases to 150 mg three times a day. According to the recommendations, the tablets should be taken after a meal, washed down with a small amount of liquid.

With intramuscular application of the injections of Midokalm-Richter, during the day 200 mg of the drug are administered in two divided doses, intravenously prescribed a single dose of 100 mg per day. When administered intravenously, the drug is injected into the vein very slowly, in a drip fashion.

When administered intramuscularly the drug immediately enters the bloodstream and acts much faster than when taking Midokalma in the form of tablets inside. The effect of the drug is characterized by the removal of muscle spasm and muscle tension located near the focus of pain. Miorelaxant contributes to blocking the transmission of nerve impulses to the cells of the motor nerves, whose task is to transfer commands to the muscles from the central nervous system.

As a result - the skeletal muscles relax, and the painful symptoms weaken. In addition to anesthesia, Midokalm has an effect on the blood vessels, expanding them, which in combination with the elimination of spasm of skeletal muscles, improves the nutrition of tissues in the lesion and significantly alleviates the condition of the patient.

For the treatment of children, Midokalm is used only in the form of oral tablets. If the child can not swallow the pill, it is ground to a powdery state, mixed with a small amount of water and given to the baby. To small patients at the age of 3 to 6 years, the daily dose of the drug is determined from the calculation of 5 mg per 1 kg of body weight.

It is divided into three parts. At the age of 7 to 14 years, the dose is calculated in the amount of 2-4 mg per 1 kg of weight and taken three times a day. Children with 14 years of age Medocamma are prescribed in the same dosage as adult patients. Sometimes Midokalm is used to treat children under one year, strictly according to the indications of a neurologist. In this case, the doctor selects an individual dosage and controls the treatment process.

The duration of the course of treatment by Miodocal is determined exclusively by a specialist and depends on the specific clinical case, age and general condition of the patient.

Contraindications

In general, the drug is safe and does not have toxic effects on the body. Nevertheless, it has a number of contraindications. Do not prescribe Miodocalum in the following cases:

• With increased sensitivity or intolerance to
• components Children under 3 years of age
• Myasthenia gravis or myasthenic syndrome

Injectable drug should not be given to patients with allergic reactions to lidocaine. In addition, treatment with injections is contraindicated in childhood. With extreme caution, one should approach the use of a solution for injections in people with impaired liver and kidney function.

Midsection during pregnancy

During pregnancy and breastfeeding use the drug is not recommended. It is especially dangerous to prescribe a drug in the 1st trimester of pregnancy.

In other cases, treatment with the drug is only possible in cases where the expected therapeutic effect for the mother will exceed the possible risk in relation to the fetus. The drug is prescribed strictly according to the indications, the course of therapy is under the supervision of a doctor.

Overdose

An overdose of the drug is very rare. In such situations, there is an increase in side effects. In severe cases, it is possible to lower blood pressure, inhibition of cardiac activity and respiration.

In children, exceeding the dosage may cause anxiety and increased irritability. Such manifestations require immediate measures, which include washing the stomach and performing symptomatic and maintenance therapy.

Side effect of

Midokalm is well tolerated by patients and has no pronounced toxic effect. But in some cases, there may be adverse reactions that quickly pass on their own with a reduced dose.

With increased sensitivity, dyspeptic phenomena( nausea, vomiting, discomfort and abdominal pain) can occur. These reactions are accompanied by the appearance of headache, weakness, a decrease in blood pressure. In case of individual intolerance of the components, allergic reactions may develop:

• Hives
• Itching
• Erythematous rash

In severe cases, development of suffocation and anaphylactic shock is possible. Such conditions are very rare, but they are fatal and require emergency medical care. When injecting Midokalma, there may be drowsiness or a feeling of slight intoxication,
, but these phenomena quickly pass.

With intravenous jet injection, it is possible to develop arterial hypotension( lowering blood pressure), so procedures should be performed by qualified medical personnel who can help with the development of such conditions.

Drug Interaction

Medication Medocalm does not have a sedative effect, so it can be used simultaneously with hypnotics and sedatives. When combined with niflumic acid, the drug enhances its effect.

Simultaneous reception with psychotropic drugs, clonidine, peripheral relaxants, means for general anesthesia, the effect of using Midokalma is enhanced. Data on interactions with other drugs are not available, as well as undesirable toxic effects of the drug on the body.

Other recommendations

Ethanol does not affect the effectiveness of the drug, so it can be used with products containing ethyl alcohol. During treatment with Mydocalm, it is not forbidden to drink alcoholic beverages. Before prescribing the drug in pricks it is necessary to specify the presence of allergic reactions to lidocaine in the patient. If any, use the drug in the form of injections can not.

Receiving Midokalma does not cause a sedation effect and can not serve as a limitation when driving a vehicle, controlling mechanisms or other actions that require speed of psychomotor reactions and increased attention.

To avoid undesirable complications, the drug should be taken strictly according to the scheme and not exceed the dosage prescribed by the attending physician. Self-medication is unacceptable.

Analogues and the price of

Midodalm has a number of structural analogues that contain a similar active substance. These drugs are Tolperisone, Tolperisone hydrochloride.

Mydocalm is a rather expensive drug. In the pharmacy network, the packing of Meadokalm 50 tablets is sold at a price of 280 to 330 rubles, the packaging of Midokalm 150 costs 300-360 rubles. The cost of the drug in ampoules for injections is from 300 to 500 rubles.

Therefore, the pharmaceutical industry produces a number of cheaper drugs that differ in composition but have similar pharmacological effects. These are such medicines, as:

• Sirdalud,
• Baclofen,
  
• Miolgin.

The main disadvantage of cheap analogues of Miodocalm is a large number of undesirable side reactions, manifested in drowsiness, lowering blood pressure and neurological disorders. Decide on the choice of the drug should the attending physician, independently replace Midokalm by analogs is not recommended.

Feedback on the application of

Review No. 1

I was prescribed Midokalm for the treatment of osteoarthritis of the knee joint. There were constant pains, could not walk, at night practically did not sleep. It was treated in a hospital. The first injections of the drug were normal. After the fifth injection, a strong dizziness, weakness, I became covered with a cold sweat, pressure dropped sharply.

I could not reach the ward myself, I was somehow brought and laid on the bed, injected an additional drug. Then it was found out that the nurse had done an intravenous injection too quickly, whereas the medication should be administered slowly, for 3 to 4 minutes. Therefore, it became so bad for me. After all it was found out, it was necessary to continue course of treatment. In general, the drug is effective and I really helped. Now I feel much better and move freely.

Ekaterina, Krasnodar

Review No. 2

Her husband Midokalm in tablets was prescribed as part of a complex treatment after an operation to remove the intervertebral hernia. He took one tablet( 150 mg) twice a day. He says that after the treatment it became much easier. I also decided to try this drug.

For a long time I am excruciated from a cervical osteochondrosis. At exacerbations there are strong pains, practically can not turn heads. By the end of the day, headaches become unbearable. Saw one tablet a night. I noticed that I feel much better in the morning, I did not feel any side effects.

Regina, Kazan

Review No. 3

For the treatment of osteochondrosis, the doctor prescribed Medikalma injections. The drug is quite expensive, but I was hoping for an improvement, because the constant pain in my back I just exhausted. Went to the procedures in the clinic. Already after the first injection I felt sick, my head began to spin, I felt sick, my legs became wadded, I could not even stand up and almost lost consciousness.

It's good that my husband and I were in a car, he helped me go down the street and drove home. I did not risk any more, and refused to take any injections. Apparently, this drug does not suit me. After a while my brother asked me for these injections and successfully pierced them, he had no side effects, and the result from the treatment was positive.

Yanina, Moscow

Review No. 4

Mildocalma tablets were prescribed to my child by a neurologist. My daughter had an increased tone. In addition, we were given a relaxing massage and coniferous baths. I do not know what helped, but after the course of treatment it became much better.

We took 1/4 tablets for a month, but I noticed that all this time the child was sluggish and capricious. After the end of the course of treatment, everything passed.

Anastasia, Togliatti