Mexidol tablets. Dosage, how to take for adults, children

Mexidol is a Russian remedy, normalizing the activity of cells of the nervous system, as well as having a pronounced antioxidant effect. The drug can be purchased in the form of tablets and solution for intravenous and intramuscular administration. The first form of release is more in demand due to ease of use and dosage.

Composition and form of release

Mexidol in tablet form are white tablets (a light cream shade is allowed) of a round biconvex shape and coated. The drug may have a characteristic aroma. The product is in transparent honeycomb blisters of 10 pcs. A cardboard box contains 3 and 5 blisters, as well as instructions for use.

The components of the tablets are:

List of components	Component Description
The main component
Ethylmethylhydroxypyridine succinate	The substance has an antioxidant effect, helps to strengthen cell membranes, reduces anxiety, fear and emotional stress, as well as activates mental activity, normalizes memory, increases immunity. In addition, the element improves adaptation and protects brain cells from adverse effects.
Minor components of the tablet
Lactose monohydrate	The component is a preservative and allows the tablets to maintain their desired shape.
Magnesium stearate	The component gives the tablets a homogeneous texture and allows the drug to maintain a given shape.
Povidone	The substance attracts and removes harmful substances from organs and tissues.
Shell components
Hypromellose	The element has a lubricating and softening effect, facilitating the movement of the tablet through the digestive tract.
Titanium dioxide	The component gives the shell the desired white color, and also prevents the penetration of moisture into the tablet.
Lactose monohydrate	The substance prolongs the shelf life of the shell.
Polyethylene glycol	A component is used to combine components.
Triacetin	The component is used as a solvent and moisture retainer. It also has a mild antimicrobial and antifungal effect.

The main element in each tablet contains 125 mg.

Terms of sale, storage, prices

Mexidol tablets (dosage of the active element in which 125 mg) can be purchased strictly with a prescription. At home, it is required to store the drug at a temperature not exceeding 25 degrees with a plus sign, and the place should be darkened and away from the access of children. Under these conditions, the drug can be stored for up to 36 months from the date of release.

You can buy a medicine in Russian pharmacies at the following cost:

Number of tablets in a package	Minimum price	Maximum price
30 pcs.	RUB 250	320 RUB
50 pcs.	RUB 410	RUB 500

The lowest cost for Mexidol tablets was recorded in online pharmacies (the understated price is justified by the absence of extra charges for delivery to the pharmacy). But it should be borne in mind that the sites may have an additional courier delivery fee.

Pharmacological properties

Mexidol tablets are included in the group of antioxidant drugs. In addition, the medication has the following effects: normalizes oxygen supply of tissues, strengthens cell membranes, protects the brain from harmful influences, and also stabilizes psychological balance, strengthens memory and activates work brain cells.

Pharmacodynamics and pharmacokinetics

Mexidol tablets (the dosage of the drug is selected optimal, for the convenience of using the product for both adults and children) after oral administration have the following effects on the body:

• prevent and slow down the development of oxidation processes that provoke damage and early aging of cells;
• make the cell membrane less susceptible to damage;
• normalize the membranes of blood cells;
• increase the ratio between proteins and lipids;
• normalize oxygen delivery to all tissues and organs, including brain cells;
• activate the protective functions of brain tissue for resistance to harmful influences;
• eliminate stress and prevent its development;
• suppress anxiety, fear and anxiety, and also reduce emotional stress;
• activate mental activity;
• improve thinking and memory;
• increase the ability to learn;
• prevent the development of seizures;
• activate metabolism in the brain;
• enhances the body's resistance to harmful factors, such as: oxygen starvation, alcohol poisoning, shock and others;
• protect cells and tissues from the harmful effects of highly toxic oxygen radicals;
• normalize the work of the heart;
• reduces the severity of symptoms with a hangover and with general blood poisoning;
• regulate the action of membrane-bound enzymes;
• activate the production of a hormone responsible for feelings: satisfaction and pleasure;
• improve blood circulation in the brain;
• normalize sleep and improve well-being during wakefulness;
• increase blood flow;
• reduce the likelihood of developing thrombosis;
• reduce the amount of bad cholesterol in the blood;
• reduces the amount of low-density fats;
• restores blood flow in the tissues of the heart after ischemia;
• reduces the manifestation of negative consequences after acute coronary insufficiency;
• prevent the spread of necrotic foci;
• normalize blood microcirculation.

After taking the tablet, it is rapidly absorbed (approximately 20-30 minutes is required) and lasts for about 5 hours. After that, the drug begins to be excreted from the body. Complete withdrawal of the drug (the active substance leaves the body mainly with urine) from organs and tissues is noted after 5 days.

Indications for use

Mexidol tablets, due to their wide spectrum of action, are used to eliminate the following pathologies:

• to normalize the condition after acute circulatory disorders in the brain tissues;
• restoration of the brain and its tissues after traumatic brain injury (TBI);
• poisoning of brain tissue with toxins;
• the presence of vascular dystonia;
• impairment of memory, thinking, attention, due to deterioration of the condition and activity of blood vessels;
• increased anxiety and nervousness;
• violation of the blood supply to the muscle of the myocardium;
• severe hangover;
• poisoning of the body with potent medicines or other toxic substances;
• chronic tiredness and fatigue;
• severe stress;
• severe oxygen starvation of tissues or the brain;
• the development of seizures;
• violation of metabolic processes in the tissues of the brain;
• severe sleep disturbance;
• tendency to thrombosis;
• violation of the state of brain tissue is not inflammatory.

In addition to the presented list of indications, Mexidol tablets are prescribed for epilepsy.

Contraindications

The doctor can prescribe Mexidol tablets only after the patient has excluded the presence of contraindications. In addition, the attending specialist strictly discusses the individual dosage of the drug.

List of contraindications for Mexidol tablets:

• severe damage to kidney or liver tissue;
• the time of bearing the child, since the effect of the drug on the fetus has not been studied;
• breastfeeding the baby. The medication is not used, since its effect on the baby has not been studied either;
• the patient's age is up to 18 years. The ban is also justified by the lack of research on the effects of the drug on the child's body;
• severe violation of the state of the walls of blood vessels;
• the presence of bleeding in the brain.

  

If you are allergic to the components of the tablets, Mexidol is also not prescribed.

Method of administration and dosage for children and adults

The dosage of Mexidol tablets is made by the doctor individually according to the general condition of the patient, as well as by the type of pathology and its severity.

Dosing rules for Mexidol tablets for adults (children are not prescribed the drug), depending on the purpose of use:

List of pathologies	Dosing rules	Duration of admission
After an acute circulatory disorder in the brain	The initial dosage is 1 tablet 3 times every 24 hours. It should be gradually increased to 2 tablets 3 times a day. The daily dosage is no more than 6 tablets per day.	14-30 days. If necessary, you can extend the treatment up to 45 days. But only with the permission of the doctor.
Normalization of blood circulation in the brain after TBI	First you need to take 1 tablet 2 times a day. Further, the dosage must be increased to 2 tablets 2 times every 24 hours.	10-20 days. The duration of the course depends on the dynamics of the treatment.
Violation of the state of brain tissue of a non-inflammatory nature	The initial dosage is 1 tablet 2-3 times a day. If necessary, the dosage is allowed to be increased to 6 tablets (divided into 3 doses).	The duration of the use of the medication is 30-45 days. Longer therapy is prescribed by the doctor.
Poisoning of brain cells with toxins	You need to take 6 tablets per day. Divide the dosage into 3 doses. No dose increase is required.	The duration of the course is set individually.
Disruption of metabolic processes in the brain	3-4 tablets should be used during the day. The dosage should be divided into 2-3 doses. (1 tablet 3 times or 2 tablets 2 times every 24 hours).	The average duration of treatment is 21-30 days. The more accurate course is determined by the treating specialist.
Vegetovascular dystonia	Use 2-3 tablets per day. Divide the prescribed dose into 2-3 doses.	45-60 days. It is impossible to use tablets longer.
Decrease in memory, attention and impairment of perception of new information	Take 1-2 tablets every 24 hours. Divide the used dose into 1-2 doses. It is not recommended to increase the dosage.	The duration of therapy is 20-30 days. Extension of treatment up to 45 days is allowed.
Increased anxiety and nervousness, stress	Take 1 tablet in the morning and evening. It is not advisable to increase the dosage.	The duration of taking the pills is 2-3 weeks.
Impaired blood supply to myocardial muscle	First, take 1 tablet 3 times every 24 hours. then the dose is increased to 2 tablets 3 times a day.	The duration of therapy is set individually.
Severe hangover	Take 1-2 tablets once in the morning.	The course is 5-7 days.
Poisoning of the body and tissues with toxins	First, use 1 tablet in the morning and in the evening. Then the dose is increased to 2 tablets (also taken in the morning and in the evening).	10-15 days. If the body does not fully recover, then it is allowed to extend the course up to 1 month.
Chronic fatigue	Take 1 tablet in the morning.	20-30 days.
Oxygen starvation of the brain and tissues	Take 2 tablets in the morning and in the evening. Then the dose is increased to 2 tablets 3 times every 24 hours.	The duration of taking the medication is 15-30 days.
Convulsions or epilepsy	Prescribe 2-3 tablets per day. Divide the dose into 2-3 doses.	The course lasts from 1 to 2 months.
Thrombosis tendency	First take 1 tablet in the morning and in the evening. Then 2 tablets in the morning and in the evening.	The duration of therapy can be from 2 weeks to 1.5 months.
Severe insomnia	Use 1-2 tablets in the evening.	Use the product for no more than 30 days.

The table shows the approximate dosage of tablets for Mexico. It should also be borne in mind that it is impossible to abruptly stop the course of using the drug. It is necessary to gradually reduce the dosage to the initial one over the course of 2-3 days.

Side effects

Mexidol tablets, the dosage of which changes from the purpose of administration, can cause (during the course of the course) the development of a negative reaction, which manifests itself in the form of:

• increased tendency to sleep, or vice versa, increased insomnia;
• headache;
• dry mouth;
• nausea, immediately after swallowing the pill;
• burning sensation, pain and discomfort in the abdomen;
• heartburn;
• bloating due to the accumulation of gas in the intestines;
• frequent and loose stools;
• flushed face;
• rumbling in the stomach;
• change in appetite;
• lack of coordination;
• jumps in the pressure indicator;
• an increase in the amount of sweat discharge;
• increased weakness and lethargy.

If the patient is allergic to the constituents of Mexidol, the development of suffocation, urticaria and other symptoms is possible.

Overdose

When swallowing more than 6 tablets at a time, symptoms of drug poisoning appear, which are expressed in the form:

• severe sleepiness;
• the development of insomnia;
• severe migraine;
• severe dryness in the mouth;
• frequent vomiting;
• severe pain throughout the abdomen;
• diarrhea;
• rush of blood to the skin;
• lack of appetite;
• high amplitude pressure surges;
• heavy sweating;
• lack of strength.

In case of poisoning with Mexidol tablets, you should rinse the sick stomach. Further treatment is usually not prescribed, the symptoms that appear disappear after approximately 24 hours. But if the symptoms persist or are severe, then symptomatic therapy is needed.

special instructions

When prescribing Mexidol tablets, the attending specialist must discuss with the patient the special conditions for taking the drug:

• the product can not be used with lactose and fructose intolerance, as well as other components of the medication;
• in childhood, the drug is not used, since the body's response to pills has not been studied;
• Mexidol can be used simultaneously with alcoholic beverages, while the drug will partially protect the liver from the harmful effects of ethanol;
• in the presence of pathologies of the kidneys and liver in severe form, the drug is strictly prohibited to use.

Mexidol tablets affect the attention and activity of the nervous system. In this regard, during the period of treatment, driving a car or performing hazardous work requires special attention.

Drug interactions

Mexidol tablets, the dosage of which is 125 mg of the main component, should be used with extreme caution when combined treatment with the following drugs:

• tablets enhance the effect of potent soothing medications;
• Mexidol increases the therapeutic effect of antipsychotics (used to normalize the psychological state);
• the drug increases the effectiveness of antidepressants;
• tablets enhance the effect of sleeping pills;
• Mexidol increases the therapeutic effect of anticonvulsant drugs;
• The medication reduces the toxic effects of ethanol on the body.

Thanks to this property of the drug, it is possible to reduce the dosage of additional medications, as a result, the likelihood of developing side effects from taking the last funds decreases.

Analogs

The doctor may prescribe analogs of the Mexidol tablet if the patient has contraindications or in cases where the drug is not on sale.

You can replace the medication with the following drugs:

List of analogues and prices	Active element and its action	Notes (edit)
Trigamma. Injection. RUB 500 On prescription.	A multicomponent drug with metabolic, local analgesic and anti-inflammatory effects.	The tool is allowed to be used from 18 years old. Contraindications and side effects include allergies and severe heart problems.
Riluzole. Pills. RUB 12,000 On prescription.	The main element riluzole affects the activity of the nervous system.	The analogue is prohibited under 18 years of age. Before starting to use it, you need to familiarize yourself with the contraindications.
Vitagamma. Injection. RUB 200 On prescription.	The multicomponent composition of a complex of vitamins helps to normalize the activity of the nervous system.	A substitute is prescribed from the age of 18. Before buying, you need to familiarize yourself with the contraindications and side effects.
Vitaxon. Tablets and injection solution. 1650 RUB On prescription.	The main components (benfotiamine and pyridoxine hydrochloride) normalize the activity of the nervous system, restore blood circulation and metabolic processes	The analogue should not be used until the patient reaches 18 years of age. Additionally, it must be borne in mind that the tool contains a sufficient list of prohibitions and side effects.
Hypoxene. Capsules. 800 RUB Over the counter.	The multicomponent agent prevents the development of oxygen starvation of tissues, and also has an antioxidant effect.	The tool is not used until the age of 18, as well as for allergies or after a recent stroke. Of the side effects, only an allergic reaction was recorded.

In addition, you can replace the tablets with Mexico with the following medicines:

• Mexiprim. Solution for injection, tablets. RUB 200 On prescription;
• Neurox. Injection. RUB 300 On prescription;
• Cytoflavin. Tablets and injection solution. RUB 500 On prescription;
• Memoria. Drops for oral administration. RUB 350 Over the counter;
• Combilipen. Solution for injection, tablets. RUB 250 On prescription.

Only the attending physician can replace Mexidol tablets. It takes into account why the analogue is selected and the general well-being of the patient.

Mexidol tablets are considered the best drug in this group. The drug quickly eliminates the symptoms of cerebrovascular accident, eliminates anxiety, and also makes the hangover "painless". In addition, the use of the drug rarely causes the development of a negative reaction, but subject to the dosage.

Author: Kotlyachkova Svetlana

Video about the drug Mexidol

Mexidol instructions and doctor's review: