Clindovit gel. Reviews, instructions for use, analogues for acne, price

Clindovitis is a medical a drug designed to treat acne. The gel has many positive reviews and is often used as part of a complex treatment.

Forms of release and composition of the drug

This drug is produced in Russia in the form of a gel for external use.

The active ingredient of the drug is clindamycin.

Additional composition:

• methylparaben E218;
• allantoin;
• propylene glycol;
• tocopheryl phosphate lauriminodipropionate disodium;
• caustic soda;
• macrogol 400;
• carbomer copolymer;
• carbomer interpolymer;
• filtered water.

The product is contained in aluminum tubes packed in cardboard containers. The nominal volume of the tube is 30 g. Each package includes a tube of gel and detailed instructions for using the drug.

Pharmacological properties

Clindovit is a gel (reviews about the effectiveness of the drug are mostly positive), which, when applied topically, exhibits some pharmacological and pharmacokinetic properties.

This medicine belongs to the category of antibiotics from the group of lincosamides. It exhibits high antimicrobial activity against propionobacteria, which provoke the development of acne.

The main substance, when interacting with a pathogenic cell, suppresses the synthesis of its protein, while acting on the ribosome of the microorganism.

The drug has no in vitro ability. However, when used locally, the medication lends itself to hydrolytic processes, as a result of which the active substance, clindamycin, is formed.

When using the gel topically, the level of free fatty acids on the skin is significantly reduced and is no more than 2% (instead of 14%).

Pharmacodynamics and pharmacokinetics

When using the drug, its components accumulate in comedones in patients with acne. In this case, the active substance of the medication begins to exhibit an antibacterial effect.

Gel action:

• suppression of pathogenic pathogens responsible for the development of acne;
• reduction and elimination of clinical manifestations - inflammatory reactions in the affected area;
• an obstacle to the further development of pathology - restoration of local microcirculation of blood, elimination of edema, spots;
• suppression of excess sebum production, which complicates the course of the pathological process;
• prevention of the development of post-acne - trophic scars, microscars.

The level of the active ingredient after topical application of the product is significantly higher than the level maximum oxygen consumption consumed by pathogenic microorganisms responsible for the development of acne rashes.

Local use of the drug leads to an insignificant content of the main substance in the patient's blood. Moreover, this concentration has no clinical significance.

Indications for use

This drug is used in the treatment of acne. It can be used both as part of a combination treatment and as monotherapy.

Contraindications

This tool has some restrictions on its use. Thus, the gel is contraindicated in the presence of high sensitivity to the components, as well as in Crohn's syndrome (ulcerative and pseudomembranous colitis).

With extreme caution, the product is approved for use in the following cases:

• children under 12 years of age;
• breast-feeding;
• allergic diseases;
• simultaneous use of gel and muscle relaxants.

Before using the drug, you must consult a dermatologist for the presence / absence of allergic reactions.

You should also check for allergies to the composition of the gel yourself. To do this, you need to apply a small amount of the product to the elbow bend. With the development of any negative manifestations (redness, itching, irritation), it is recommended to refuse further use of the drug and seek advice from a treating dermatologist.

At what age can the drug be used?

Clindovit is a gel (reviews and instructions for the tool inform about the possibility of its use in pediatric practice), which can be prescribed to children and adolescents. However, with a high degree of caution, the gel should be prescribed to children under 12 years of age, since there is no experience of using the drug at this time.

In this case, treatment should be carried out under the supervision of a pediatrician or dermatologist.

Instructions for use, dosage

The product is intended for outdoor use. Apply the drug to the affected skin with a thin layer. Before applying the gel, it is recommended to pre-clean the skin.

Applied in this way from 2 to 3 times a day, depending on the severity of the pathology.

The duration of treatment is 6 to 8 weeks. If necessary, and only on the recommendation of a doctor, therapy can be continued for six months.

In the absence of a therapeutic effect within 2 months, it is recommended to consult with a treating dermatologist.

Side effects

Usually, the drug is well tolerated by all groups of patients and does not cause negative reactions. However, in rare cases, the drug can lead to the development of side effects associated with the action of the active substance or the individual characteristics of the patient's body.

Side effects:

• irritation on the applied area;
• itching;
• excessive dryness of the skin;
• the development of erythema;
• peeling formation;
• excess sebum production;
• contact dermatitis;
• pseudomembranous colitis.

If a side effect occurs, including symptoms not listed in the annotation, it is necessary to cancel further medication and consult a treating dermatologist.

Overdose

Data on the development of symptoms of overdose are not provided. However, if the indicated dosages are significantly exceeded or if the agent is accidentally swallowed, it is necessary to contact the attending specialist for the appointment of symptomatic therapy.

In case of accidental ingestion of the drug, it is necessary to use sorbents (activated carbon) and contact a medical institution for gastric lavage.

special instructions

Clindovit is for external use only. According to patient reviews, the gel has a soft texture and is easily applied to the skin.

When using the medication, avoid contact with the eyes or mucous membranes of the mouth. After applying the composition to the skin, it is recommended to thoroughly wash your hands with soap and water.

The medicine can be prescribed during the period of bearing a child. However, the decision on the possible use of the drug during pregnancy should be made by the attending specialist, taking into account the possible risks / benefits for the mother and the unborn child.

The use of the drug during breastfeeding should be abandoned, since there is no data on the penetration of the active substance of the gel into breast milk. If it is necessary to use the medication, it is recommended to stop breastfeeding for the entire period of treatment.

The drug does not have a depressing effect on the psyche or visual functions of a person. Therefore, it is allowed to drive a vehicle or carry out other work requiring high psychomotor functions.

Drug interactions

The drug exhibits some drug interactions when administered simultaneously with other medications. Thus, it is not recommended to combine the drug with erythromycin and clindamycin. This combination can lead to a decrease in the therapeutic effect of the gel.

When combining the drug with lincomycin, cross-resistance may develop.

The simultaneous use of the main agent with muscle relaxants can lead to an increase in the effect of the second group of medicines. In this case, there is a violation in the transmission of neuromuscular impulses.

When taking other medications during the period of application of the gel, you should inform the attending specialist about this in advance. This will avoid the possible development of drug interactions.

Analogs

Clindovit is a gel (reviews of the tool declare high risks of developing allergic reactions), which, if intolerance reactions occur, must be replaced with another similar drug.

The selection of the drug is made taking into account the pharmacological group and identical indications.

Analogs:

• Zenerite. This medicine is produced in Denmark as a gel for external use. The active ingredients are: zinc acetate and erythromycin. The medicine belongs to the category of local antiseptic and disinfectants. The drug exhibits antimicrobial, anti-inflammatory and comedolytic effects. In this case, the drug has an activity aimed at suppressing propionobacteria and epidermal streptococcus. The indications for the use of the gel are acne eruptions. The drug is contraindicated in the presence of intolerance to the active ingredients that make up the product. During pregnancy, the remedy should only be prescribed by the treating specialist, taking into account the potential risks and benefits. In childhood, the medication is used only under the supervision of a pediatrician (dermatologist). Apply only externally. The agent is applied 2 times a day with a thin layer on the affected area. Use in the morning and evening. The duration of treatment is from 2.5 to 3 months. The first result appears after 2 weeks of application. Dispensing method - over-the-counter. The cost of the gel in pharmacies in Moscow and the Moscow region can vary and ranges from 515 to 719 rubles. per packing.
• Klenzit-C. This drug is made as a topical gel by an Indian pharmaceutical company. The remedy has 2 active substances - clindamycin and adapalene. The drug belongs to the group of local antiseptic and antimicrobial medicines. The drug has a local anti-inflammatory, antibacterial and comedolytic effect. It is effective in the treatment of various skin lesions caused by the action of propionobacteria. The indication for the use of the medication is acne. Restrictions to the appointment of the gel are the following conditions and disorders: allergy to the drug, ulcerative colitis, Crohn's syndrome, period of gestation and breastfeeding, children under 12 years of age. It is allowed to use the remedy with extreme caution for dermatitis, eczema, allergic diseases. Apply the gel to the affected areas 1 time per day before bedtime. The treatment is carried out for 3 months. The therapeutic effect occurs in 2-4 weeks. Repeated courses are allowed after a break and prior consultation with a dermatologist. Vacation conditions - without a prescription. The price of the drug in Russian pharmacies varies between 400-765 rubles.
• Baziron AC. This drug is produced in Switzerland in the form of a gel for external use, the active ingredient of which is benzoyl peroxide. The drug belongs to the category of antiseptic and disinfectant medicines. It exhibits keratolytic and antimicrobial effects aimed at suppressing propionobacteria and staphylococcus epidermidis. The gel is used as a treatment for acne breakouts. List of restrictions: children under 12 years of age, allergy to the components that make up the drug. The gel is applied 1-2 times a day in a thin layer, covering the affected area. The effects of taking the drug are noted after the expiration of the first month of treatment. A lasting result occurs at the end of a 3-month course. Re-therapy is possible after a long break and preliminary consultation with a specialist. The way of implementation is without a prescription. The cost of the gel in Moscow and regional pharmacies ranges from 728 to 891 rubles.
• Skinoren. The manufacturer of this medication is Italy and Russia. The product is produced in the form of a gel or cream for external use, the active substance of which is azelaic acid. It belongs to the class of topical antiseptic and antibacterial drugs. The drug has anti-acne and anti-inflammatory activity aimed at suppressing Staphylococcus epidermidis and propionobacteria. Indications for the use of both dosage forms: acne, the presence of hyperpigmentation, rosacea, including the presence of papules and pustules. A restriction on the use of the drug is children under 12 years of age, as well as an allergy to the components of the medication. Use a cream / gel with extreme caution in bronchial asthma. Apply the product 2 times a day - in the morning and in the evening. The duration of use is from 1 to 3 months. In the absence of a therapeutic effect within 3 months, it is recommended to cancel the use of the gel / cream and consult a dermatologist. Repeated courses are possible only after a break and a preliminary consultation with a doctor. The method of sale is without a prescription. The cost of a medicine in commercial and state pharmacies in Moscow ranges from 496 to 1490 rubles. per packing.
• Differin. This medicine is produced in France in the form of a cream or gel for external use. Adapalene acts as the active ingredient of the drug. The drug belongs to the category of local anti-inflammatory and comedolytic drugs. This medication is prescribed to treat acne. Avoid using the product if you are allergic to one of its components. Extreme caution is allowed to use the cream / gel in the presence of dermatitis or eczema. The composition is applied to the affected areas with an even thin layer. Use once a day before going to bed. The therapeutic effect develops within 1-2 months of treatment. The recommended duration of therapy is 1 to 3 months. Persistent improvement is noted at the end of the course - 3 months. Repeated courses are allowed after a break and prior consultation with a dermatologist. The method of sale is without a doctor's prescription. The cost of packaging in regional and regional pharmacies in Russia is 600-826 rubles.

Clindovit - gel (patient reviews on the drug indicate the need for prolonged use of the gel), which should be replaced with similar drugs only by the attending specialist, taking into account the severity diseases.

You should not select analogs on your own, since an incorrectly selected agent can cause a deterioration in the condition or cause various allergic reactions.

Terms, conditions of sale and storage

• The gel should be stored in a dry and clean place at temperatures between 15 and 25⁰C.
• The shelf life of the funds is 24 months.
• Do not use the drug after the expiry date indicated on the package.
• Terms of sale - without a prescription.

Price

The cost of the topical gel may vary depending on the area and region of sale. The price is also influenced by the retail pharmacy chain that sells medicines. You can find out the exact cost of a medicine at any pharmacy located in your place of residence.

Sales area / region	Shape / volume	Price
Moscow, Moscow region	Gel, 1%, 30 g	RUB 350-388
St. Petersburg	Gel, 1%, 30 g	RUB 402-473
Saint Petersburg (suburbs)	Gel, 1%, 30 g	RUB 398-452
Leningrad region	Gel, 1%, 30 g	RUB 400-424
Novgorod region	Gel, 1%, 30 g	RUB 389-453

Before using Clindovit, you must carefully study the annotation for the use of the gel and consult a dermatologist. Additionally, it is recommended to read the reviews of patients who have used the drug as a treatment for acne.

Video about the drug

Clindovitis against acne: