Klenzit-C (Klenzit-C). Price, instructions for use for acne, reviews, analogues

Klenzit-S is combination remedy for the treatment of acne, which contains effective active ingredients and rather quickly treats rashes of varying degrees of neglect.

The medication is used after a preliminary examination to clarify the cause of the rash. The price of the drug is quite high, but the effectiveness fully justifies it, so the medication is often prescribed.

Forms of release and composition of the drug

The drug is available only in the form of a gel for topical external use. The gel is thick, has a uniform consistency and a specific aroma, easily spreads over the skin and is well absorbed.

The drug is packaged in special small tubes of 15 or 30 g. Each tube is in an individual cardboard box, instructions for use are also attached to it. The gel contains 2 active components that have a therapeutic effect - adapalene and clindamycin.

The medicine contains auxiliary ingredients:

• Phenoxyethanol.
• Sodium hydroxide.
• Edetate disodium.
• Propylene glycol.
• Purified water.

The excipients have no therapeutic properties.

Pharmacological properties

Klenzit-S (the price of the product depends on the region of distribution) has anti-inflammatory and bacteriostatic properties, which makes it possible to use it for various types of rashes on the face or body.

An additional property of the drug is comedolytic. The action of the gel is aimed at treating acne of varying degrees of neglect and preventing its recurrence. The substances in the composition have a positive effect on the skin, stimulate their recovery, and improve the appearance.

Against the background of the use of the remedy, not only the elimination of external manifestations occurs, but also a significant decrease in the risk of the transition of pathology to a chronic form is observed.

Pharmacodynamics and pharmacokinetics

After applying the agent to the affected area, the active components have a therapeutic effect. The bacteriostatic effect is provided by the content of clindamycin.

This ingredient helps to stop the development and reproduction of many microbes that provoke the appearance of comedones, acne and other types of rashes. The component stops the development of microbes, which leads to their gradual death and an improvement in the condition of the skin.

After the destruction of microbes, the signs of the inflammatory process are eliminated, tissue swelling and discomfort, which is often present during inflammation, disappear.

The medication also has other properties:

• The active component adapalene belongs to the group of retinoid derivatives, therefore it has pronounced regenerating properties.
• It is due to the presence of adapalene in the composition that the comedolytic effect is carried out. The component helps to suppress the process of binding of follicular cells of the epithelium, which leads to a decrease in the foci of inflammation on the skin and significantly improves the condition of the tissues.
• After elimination of edema and signs of inflammation, a significant acceleration of the restoration of the skin is observed.
• Comedones and blackheads gradually disappear after pus and dead skin cells are naturally removed from them.
• Even in the absence of additional therapy, there is an improvement in the appearance of the skin and a decrease in the number of lesions, up to complete disappearance.
• The medicine accelerates the process of tissue repair due to the presence of adapalene in the composition.

After applying the product to the skin, its absorption occurs rather quickly. The active ingredients are concentrated in the upper soybeans of the skin, and are absorbed in a minimal amount into the systemic circulation. The concentration of substances in the skin depends on the duration of use and the thickness of the gel layer.

In the study of blood, it is not possible to detect active substances, which proves minimal systemic absorption. A small amount of components is processed in the liver, after which they are excreted with the help of the kidneys and with feces. The components of the composition do not accumulate in the body, which is considered an advantage over other drugs for topical use.

Indications for use

Klenzit-S is prescribed to patients of different ages and with various accompanying deviations, despite the high price of the gel.

Main indications for use:

• Acne on the face, chest, or upper back.
• Open and closed comedones. The tool helps to treat even advanced forms of pathology, but with the therapy of closed comedones, the therapeutic effect occurs somewhat later.
• Acne on the face.
• A rash on the face, back and chest caused by bacteria sensitive to clindamycin.

It can also be used in combination with systemic medications to help enhance effectiveness.

Contraindications

The gel is not prescribed when identifying individual intolerance to the components of the composition or a tendency to similar manifestations.

Other contraindications include:

• The period of gestation and breastfeeding. The medication can provoke complications in the mother and child.
• Eczema and dermatitis in the acute stage. With caution, the medicine is prescribed for the chronic course of such diseases, only after examination.
• Psoriasis in the acute stage.
• Infected purulent wounds in the area of ​​application of the product.
• Trophic ulcers and burns on the face or other part to which the agent is applied.
• Herpetic foci in the area of ​​the rash.
• Violation of the integrity of the upper layer of the skin at the site of the intended application of the product.

With caution, the drug is used to treat patients who have previously suffered from allergies to drugs containing similar active ingredients.

At what age can the drug be used?

Klenzit-S (the price of the product differs depending on the amount of gel in the tube) is allowed for use by patients over 14 years old.

At an earlier age, the drug is used only after a doctor's examination and when such a need arises.

Instructions for use, dosage

The drug is used only externally according to a certain scheme. Depending on the type of rash, the use may differ, as well as the duration of the therapeutic course.

The standard scheme of application involves the application of the agent pointwise directly to the affected area. It is recommended to use a clean cotton swab for this. A small amount of gel is applied to the affected area in a rather thin layer, do not rub.

The application is repeated for 2 weeks, once a day. After that, the doctor evaluates the result and can extend the therapy up to 4 weeks. Longer term use is not recommended. If necessary, repeat the course, you should take a break for at least 2 months. If the specialist does not see improvement within 7 days, he may increase the dosage. In this case, the patient applies the gel 2 times a day.

If the patient has large comedones, acne on the face or other area, it is allowed to make applications with a remedy, that is, apply a thick layer of gel on the affected area and apply a small piece of gauze on top, which should not significantly exceed the area hearth.

After 1 hour, the gauze is removed, the manipulations are repeated daily for 1-2 weeks. In case of repeated use, the patient must first visit a doctor who will determine the appropriateness of an additional course.

Side effects

Klenzit-S (the price of the drug is quite high, so not every patient can undergo a therapeutic course) often leads to the development of negative reactions if the instructions are violated. Compliance with all the rules does not guarantee the absence of complications.

Organs and systems	Most common adverse reactions
Digestive tract	Disorders from the digestive system are manifested in the form of nausea, vomiting and stool disorders. Sometimes there is constipation or frequent loose stools, which depends on the characteristics of the patient's body and the nuances of nutrition. With prolonged persistence of symptoms, indigestion is observed and pain appears in the stomach and intestines.
Nervous system	The drug rarely provokes complications from the nervous system. In most cases, they manifest themselves in the form of headache, dizziness, weakness and fatigue. The condition can be aggravated as a result of sleep disturbances, depressive disorders. After discontinuation of therapy, the symptoms disappear, special treatment is required in some cases.
Mucous membranes	From the side of the mucous membranes, complications appear when the patient develops an allergic reaction. Patients experience swelling of the mucous membranes of the mouth, nasal passages, eyes. As the condition progresses, itching and inflammation join. Usually, the manifestations do not disappear on their own; therapy aimed at eliminating the disorders is required.
Skin	Patients often develop an allergic reaction when using the drug for a long period of time. It manifests itself in the form of itchy skin, irritation and flaking. Often, a rash appears on the body, spreading to large areas. When combing lesions, symptoms of inflammation join, and there is a threat of tissue infection.

The severity of negative reactions depends on the duration of the use of the gel, as well as the amount of the applied drug at a time.

Overdose

The minimum absorption of the drug into the systemic circulation significantly reduces the risk of overdose, but does not completely exclude it. Sometimes, with prolonged use, an acute allergic reaction may develop, affecting the skin, mucous membranes.

At the first stage, patients develop a rash on the body, burning and irritation. Somewhat later, itching joins the symptoms. The rash spreads over large areas, which worsens the condition, leading to scratching of the affected areas and damage to the outer layer of the skin.

On the part of the mucous membranes, there is swelling and inflammation, discomfort. Many patients report lacrimation, the discharge of a large amount of clear mucus from the nose, as well as discomfort in the mouth when eating or taking fluids. The appearance of symptoms of an overdose is considered a reason for refusing to use the medication.

The patient is assisted in a hospital setting. Usually, the introduction of an antihistamine is sufficient; in some cases, the use of parenteral glucocorticosteroids is indicated. Within 2-3 days, the condition is normalized, the patient is sent home.

special instructions

Klenzit-S (the price of the medicine may vary depending on the specific pharmacy) can be used after a preliminary examination by a dermatologist. If the rash is the result of an infectious or viral disease, the drug should be discontinued. It is not used in the case when the patient has recently used drugs with similar therapeutic properties.

When applying the gel, it is important to ensure that it does not fall on healthy areas of the skin and mucous membranes. If the medication gets into your eyes, you should immediately rinse them with clean water and visit a doctor. A specialist examines the eyes and, if necessary, prescribes special drops to eliminate irritation.

If there is no therapeutic effect within 10 days, the doctor may cancel the medication and prescribe another one. In the first few days after starting to use the medication, the condition of the skin and acne may worsen. Symptoms usually disappear after 3-5 days. During the period of therapy, direct sunlight should be avoided. It is also forbidden to visit the solarium.

If it is impossible to avoid contact with the sun's rays, the application of the product is carried out no later than 24 hours before the alleged exit to the street. Otherwise, complications may arise in the form of age spots and the formation of areas of inflammation.

Drug interactions

You should not use the medicine at the same time as other medicines containing the same active ingredient or having the same therapeutic properties. The drug has no effect on the action of systemic medicines, which makes it possible to combine it with many other drugs.

Despite this, you should not use the medication at the same time as alcohol-containing liquids, as well as ointments, creams with drying properties.

Simultaneous treatment with gel and products containing calcium gluconate, magnesium sulfate is not recommended. The use of a drug in combination with Erythromycin leads to a weakening of the effectiveness of both drugs.

Specialists also do not prescribe therapy in combination with Ampicillin and B vitamins. If you need to use the medicine at the same time as any means, you should first consult with a specialist.

Analogs

The medicine has analogues that are allowed to be used in the absence of the original medicine in pharmacies.

Most popular substitutes:

• Azix-Derm - a preparation in the form of a cream, which contains azelaic acid as the main active ingredient. The medicine has anti-inflammatory and antimicrobial properties, helps to treat acne and pathological pigmentation. The tool is considered effective, it is applied only topically, and is often prescribed in combination with other medicines.
• Azogel - a gel for external use, which contains azelaic acid and helps to fight rashes, acne and acne of various origins. The drug is applied pointwise to the affected area, it is considered quite effective and helps to get rid of acute symptoms and inflammation in a short time. The medicine is prescribed for adults and adolescents, but only in the absence of infected or purulent wounds in the place of the alleged infliction of skin lesions.
• Regetsin - an effective gel for the treatment of acne and other types of rashes on the face, upper back, chest. The drug has an effect due to the content of zinc hyaluronate, which has regenerating, anti-inflammatory and antimicrobial properties. After completing the course of therapy, a significant reduction in the number of lesions is observed, as well as an improvement in the condition of the skin by accelerating the process of cell renewal.
• AcneStop - a drug based on azelaic acid, which is produced in the form of a cream for external use. The medication is considered quite effective and helps to eliminate most of the rashes in a short period of time.
• Skinoren - gel for external use, which has antimicrobial and anti-inflammatory properties. The tool helps to quickly eliminate signs of inflammation and prevents the reoccurrence of lesions.

Analogs of the drug may contain other active ingredients, may be more expensive or cheaper than the original medication. That is why it is important to select a substitute with the help of a specialist.

Terms, conditions of sale and storage

The drug can be stored for 2 years. The production date is indicated on the packaging, use after the expiration date is prohibited.

During storage, it is important to exclude direct sunlight on the gel and restrict access to children. Dispensing drugs from pharmacies is carried out on prescription from a doctor.

Price

The cost of the medication depends on the region of distribution and the amount of gel in the package. The average price is 550-800 rubles.

Klenzit-S is one of the most popular drugs for the treatment of acne of various origins. Despite the high price of the drug, the use helps to quickly improve the condition of the skin and prevents the progression of the disorder.

Video about the drug

Klenzit-S acne treatment: