Mupirocin (Mupirocin) nasal ointment. Price, instructions for use, reviews

Mupirocin is an antibacterial medication, which is used to improve the condition in pathologies of bacterial origin with damage to the mucous membranes and skin.

Nasal ointment has a different price, is prescribed in short and long courses, helps to eliminate acute symptoms of diseases, and prevents the spread of the inflammatory process to healthy tissues.

Release form and composition of the drug

The medication is available in the form of an ointment for topical external use. It has a standard thick consistency, a specific medicinal aroma, and easily spreads over tissues.

The product is packaged in 15 g aluminum tubes, which are placed in small cardboard boxes. They also contain instructions describing the nuances of use and possible complications during treatment. The composition of the product contains the active substance mupirocin, which has a therapeutic effect on tissues.

Other substances are present as auxiliary ingredients in the composition:

• Macrogol.
• Polyethylene glycol.
• Composition for forming the consistency of the product.

Additional components do not have medicinal properties.

Pharmacological properties

Mupirocin is a nasal ointment, the price of which can be high, depending on the manufacturer. It has strong anti-inflammatory and antibacterial properties. The tool destroys bacteria and prevents the development of complications against the background of the progression of the inflammatory process, its spread to large areas of healthy tissues.

The tool also prevents the recurrence of symptoms when pathogens enter the repaired tissue. The agent also has bacteriostatic properties, that is, it inhibits the growth and development of many bacteria.

The complex effect on the tissues avoids the development of complications that will certainly arise in the absence of therapy.

Pharmacodynamics and pharmacokinetics

When applied to mucous membranes and skin, it begins to act almost immediately. The active ingredient inhibits the growth of bacteria and destroys them, preventing multiplication and subsequent worsening of symptoms.

The activity of the active substance against gram-positive and gram-negative microorganisms is noted, which can provoke complications and tissue infection. The remedy helps to relieve inflammation, as it destroys bacteria that provoke tissue swelling and redness. As a result, the condition of the patients is significantly facilitated.

The tool has other properties:

• Destroys micrococci, staphylococci at different stages of development. These agents most often provoke inflammation and aggravate symptoms.
• Helps fight many gram-negative bacteria, therefore it has a wide range of antimicrobial activity.
• Stimulates tissue regeneration and cleansing of waste products of microorganisms.

When applied topically, the agent is almost not absorbed into the systemic circulation, especially in the absence of damage to the skin. Despite this, the medication is considered to be very effective and safe. With long-term treatment, its components accumulate only in the upper layers of the skin, which provides a long-term effect, even after the end of the treatment course.

An external medication, when used in the area of ​​violation of the integrity of the skin, is rather quickly absorbed into the blood and spreads throughout the body. It does not accumulate in the blood. The maximum concentration in the body is observed after 2-3 hours, it gradually decreases. The main ingredient is processed in the liver, where it breaks down into several metabolites.

The excretion of the substance is carried out within 1 day, while the main amount of metabolites is evacuated with the help of the kidneys. With damage from the urinary system, a slowdown in the excretion of substances from the body is observed, which can lead to its accumulation in the body and the development of complications. Pharmacokinetic characteristics may differ in different patients.

Indications for use

Mupirocin is prescribed for various diseases, despite the price, which can be quite high.

Nasal ointment is commonly used for the following disorders:

• The recovery period after surgery on the nasal passages, maxillary sinuses, nasopharynx. In this case, the remedy helps to avoid the development of complications.
• Herpetic tissue damage. The drug is not effective against herpes, but use in combination with special antiviral agents is sometimes required to avoid infection.
• Staphylococcal infection on the skin, accompanied by various complications and acute symptoms.
• Demodectic mange is not considered a direct indication for use, nor in some cases, treatment of lesions helps to eliminate some symptoms and the addition of the inflammatory process.
• Boils in the area of ​​the external auditory canal or on other parts of the body.
• Eczema of an infected origin, in which inflammation spreads to large areas of the skin.
• Infected wounds, cracks.
• The presence of insect bite marks on the skin, as well as inflammation of the skin in this area.
• Burns, accompanied by the addition of infection, the development of the inflammatory process.
• Inflammatory pathologies of the mucous membranes of the nasal passages against the background of the development of staphylococcal infection.

The drug can be used not only for pathologies of the nasal passages, but also for many other disorders.

Contraindications

The ointment is not prescribed to patients who have an acute or subacute form of intolerance to the main component of the composition or auxiliary ingredients.

Other barriers to therapy:

• Fungal lesions of the skin or other tissues affected by bacteria. The drug can worsen symptoms.
• Pregnancy and lactation period. In case of violation of the integrity of the skin, the drug is not used, but in the presence of a mild form of inflammatory disease, it is allowed to use it.
• Atrophic form of rhinitis, in which there is a constant nasal congestion. The remedy can lead to a deterioration in the condition, as well as the development of complications, so you should not use it.

The severe course of some dermatological diseases is considered a relative contraindication for external therapy. In each case, the decision on the prescription of the medicine is made only by the doctor.

At what age can the drug be used?

Mupirocin is a nasal ointment (the price of the medicine may depend on the volume of the tube), which is allowed to be used for the treatment of patients under 3 years of age.

Only in some cases, the medicine is prescribed for children under 3 years old, but the decision is made by the pediatrician based on the examination data.

Instructions for use, dosage

The tool is used only externally in the prescribed dosage and according to a certain scheme:

• For adults, a standard method of treatment is used, which involves treating the affected area no more than 4 times a day. The therapeutic course lasts no more than 10 days. If necessary, it can be repeated, but only after a break of 2-3 weeks.
• When using the product for children from 3 to 14 years old, the ointment is applied no more than 2 times a day with equal time intervals.
• Adolescents from the age of 14 are treated according to the standard scheme used for adults.

Depending on the disease, the therapeutic effect occurs over a different period of time. It can also depend on the individual patient's body.

With herpes

In case of the appearance of foci of herpes infection, the drug is used within 5 days. At the same time, one should not expect an instant effect. An antibacterial drug does not have antiviral properties, therefore it only helps to prevent the development of complications.

Usually, the treatment of foci is carried out no more than 2 times a day, but this cannot be combined with the application of antiviral ointments or gels. When processing with different means, it is worth taking a break for at least 60 minutes.

With staphylococcal infection

In case of skin lesions with staphylococci, the agent can be used up to 4 times a day, treating the affected area with a thin layer. Treatment usually lasts no more than 7 days, but if necessary, it can be extended to 10 days without the risk of complications.

For adults, the medicine can be applied under a bandage, which enhances the penetration of the components into the tissues, and also increases the effectiveness. With this method of use, it is allowed to apply the ointment in the morning and in the evening and no longer than 5 days in a row. For the next 2-5 days, it is allowed to apply the product externally without the subsequent application of a bandage.

Prevention after nose surgery

After surgery on the nasal sinuses or mucous membranes, the ointment is used in short courses with the treatment of lesions no more than 3 times a day. Application continues for 5-7 days, longer use is not recommended.

If during the prophylactic course complications arise or signs of inflammation appear, you should stop using and consult a doctor.

With demodicosis

Mupirocin is a nasal ointment (the price of the medicine is quite high), which can be used to diagnose demodicosis. With such a violation, tissue damage is noted with a special type of mite, which leads to the development of inflammation.

The remedy does not help to completely get rid of the symptoms, but it significantly reduces the risk of complications as a result of the spread of the inflammatory process. The affected area is treated 3-4 times a day, a thin layer of ointment is applied. Treatment usually lasts no longer than 7 days.

Side effects

The drug can provoke complications that affect not only the affected area. This is especially often observed when used in areas of violation of the integrity of the skin, when a large amount of the drug enters the systemic circulation.

Damage area	Most common reactions
Nervous system	On the part of the nervous system, disorders occur with an increased content of the basic substance in the blood. The condition worsens with the addition of headache, dizziness, severe weakness and sleep disturbance. In this case, the symptoms may worsen if treatment continues. In some cases, it disappears on its own. Others require the use of special medications.
Digestive organs	On the part of the digestive tract, complications appear in the form of upset stools, pain in the intestines and stomach, as well as nausea and vomiting. The condition is aggravated with heartburn, as well as intense thirst. Simultaneously with these symptoms, dehydration develops, which is associated with the loss of a large amount of fluid with vomit and feces.
Vessels and heart	Vascular and heart disorders appear in patients suffering from chronic forms of any disease. Some talk about fluctuations in blood pressure, pain in the heart and aggravation of the symptoms of the underlying disease.
Leather	On the part of the skin, disorders appear in the form of an allergic reaction, accompanied by a rash, irritation and the appearance of areas of redness. If the patient combs the affected area, all reactions may worsen, as well as the addition of a secondary infection.
Mucous membranes	The mucous membranes suffer with prolonged use of the drug or with the development of an acute allergic reaction in the patient. In this case, there is swelling, redness. The process involves the mucous membranes of the eyes, nose and mouth, which leads to a deterioration in smell, vision and disruption of the process of eating.

The severity of complications differs depending on the patient's body and the duration of the use of the medication. If complications from organs or external tissues appear, you should immediately abandon treatment and visit a doctor. Often, symptoms disappear without special treatment, but sometimes antihistamines and other medications are required.

Overdose

Mupirocin is a nasal ointment, the price of which differs in different pharmacies, which does not provoke an overdose if used correctly. Such cases have not been recorded by specialists, which is associated with minimal systemic absorption.

The absence of data on an overdose of a medication is not considered a reason for its uncontrolled use without a preliminary examination and a doctor's prescription. It is especially important to observe this rule when treating children.

special instructions

When using a medicine for the treatment of the mucous membranes of the nasal passages, it is worth injecting the ointment with caution. It is better to use a cotton swab for this manipulation, which will apply the thinnest possible layer.

During the period of nasal therapy, it is worth abandoning other medications, it is especially important not to use vasoconstrictor drops or sprays. For the treatment of patients with kidney pathologies, the ointment is used with extreme caution. In case of contact with the mucous membranes of the mouth or eyes, it is important to immediately rinse them with water. If the manifestations persist, you should consult a doctor.

Drug interactions

The drug does not affect the action of systemic drugs, since, with proper use, it is absorbed into the blood in a minimal amount. Application simultaneously with other ointments is prohibited.

It is also not necessary to combine the treatment of the nasal passages with other local medicines. In each case, the doctor decides on the appointment of a particular medication.

Analogs

The drug has analogues that can be used in the absence of the original drug in pharmacies.

The most effective substitutes:

• Fucidin available in the form of a topical cream which contains fusidic acid as the main active ingredient. The tool has anti-inflammatory and antimicrobial properties, it is considered quite effective.
• Baneocin contains antimicrobial and antifungal components, has a wider spectrum of action. The medicine is prescribed for different patients and for various disorders, it is considered effective and relatively safe, available in the form of an ointment.

Analogues are used only as directed by a doctor. Self-administration can cause complications.

Terms, conditions of sale and storage

When storing funds, it is worth limiting access to children, as well as excluding exposure to sunlight. The maximum storage time is 2 years.

You can buy a medication at a pharmacy with a prescription from a doctor. Application after the expiration date is prohibited.

Price

To date, pharmacies do not have a product with this name. But you can buy medicines that contain mupirocin, for example, Supirocin or Bactroban. Their price ranges from 400-600 rubles.

Mupirocin is an effective medication that has pronounced antibacterial properties. Nasal ointment has a fairly high price, but its effectiveness justifies the cost. Many patients who have used the medicine report the disappearance of symptoms within 3-6 days, which is considered a good result.

Video about the drug with mupirocin

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