Nise is a potent drug to eliminate pain and fever. The drug is produced by an Indian pharmaceutical company in the form of tablets and gel. The main component for both forms (nimesulide) has not only antipyretic and analgesic effects, but also prevents the development of inflammation, bronchospasm.
The drug stands out among its analogues by the speed of achieving a therapeutic effect, which occurs (as with oral and external use) approximately 15 minutes after application and can persist up to 12 hours.
The disadvantage of the drug is not quite the budget price, therefore, if long-term treatment is required, cheaper substitutes can be used.
Record content:
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1 Domestic and imported analogues of the product
- 1.1 Ibuprofen gel
- 1.2 Traumeel
- 1.3 Dimexide for external use
- 1.4 Nurofen gel
- 2 Prices
- 3 Video about the drug Nise
Domestic and imported analogues of the product
Nise - gel (analogs are cheap or expensive, can only be prescribed by a doctor), which is recommended by experts to quickly eliminate pain symptoms in the joints.
The drug has not only high efficiency, but also contraindications and side effects, in the presence of which it is necessary to replace the drug with analogues. Further, the most similar in therapeutic properties, as well as more budgetary analogs, are considered.
Ibuprofen gel
If you need to replace Nise gel, you can use Ibuprofen ointment or gel, which are produced not only abroad (Belarus, USA, China), but also in Russia. The active ingredient in both forms of release is ibuprofen in an amount of 50 mg per 1 g of the drug.
The main component has antipyretic, analgesic and anti-inflammatory properties, and also reduces the number of platelets in the blood. The therapeutic effect is observed in about 40-60 minutes after applying the product to the skin.
Ibuprofen ointment and gel (like the original) is prescribed to eliminate pain symptoms in the joints, muscles, as well as to reduce pain and swelling in case of injuries (provided that there are no open wounds). Due to the use of different main components, contraindications to the use of an analogue differ when compared with Nise gel.
| Prohibitions on the use of ibuprofen | Contraindications for Nise gel | General prohibitions |
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Ibuprofen should be used with extreme caution in the first two trimesters of pregnancy.
A single dosage for both drugs is selected by the doctor individually. Ibuprofen should be applied to the skin 3-4 times a day for 2-3 weeks, and Nise should be applied 2-3 times during the day, the duration of the course is 10 days.
When using Ibuprofen and Nise, the following side effects may occur:
- the development of an allergy to the composition, manifested mainly by rashes, swelling and itching of the epidermis;
- burning sensation at the site of application of the product;
- increased sweating;
- a decrease in the number of platelets in the blood;
- redness of the epidermis;
- peeling of the skin at the site of application of the gel.
When applying funds to large areas of the skin or with prolonged use of drugs, it is noted:
- pain in the abdomen;
- violation of the condition and activity of the organs of the digestive tract;
- nausea, heartburn, development of vomiting is possible;
- frequent and loose stools;
- headache;
- the appearance of blood in the urine;
- development of swelling of the extremities;
- violation of the composition of the blood.
If any side effect occurs, you should stop using the product (both the original and the analogue). Further, the doctor can adjust the dosage or prescribe a different medication. In case of accidental oral administration of the drug (typical for both medicines) the patient may experience the following symptoms:
- profuse vomiting;
- severe abdominal pain due to a violation of the condition of the tissues of the digestive tract;
- headaches that cannot be eliminated with medication;
- inhibition of reactions;
- noise in ears;
- depression and increased sleepiness;
- a sharp increase in the pressure indicator;
- violation of the rhythm of heart contractions;
- development of intestinal bleeding;
- impaired renal function;
- cessation of breathing.
With a large swallowing of drugs, the development of a coma is possible. In case of an overdose, it is necessary to wash the stomach within the first hour after poisoning, after washing it is required to take sorbents and laxatives. If the time is "lost", then you need to call an ambulance, then the doctors perform symptomatic therapy.
You can buy Ibuprofen ointment and gel without a prescription in the same way as the original. If it is necessary to use the original or tax in complex therapy (with both oral and external medicines), a doctor's permission is required. Otherwise, the likelihood of increased side effects is high.
Traumeel
Nise is a gel (cheap analogs with a natural composition are more popular due to the smaller list of contraindications and side effects), which can be replaced with German gel or Traumeel ointment.
The main substances in the composition of the product are extracts of 11 herbs and mineral complexes that have anesthetic, anti-inflammatory, immunomodulatory action, as well as improve blood circulation and prevent the formation of exudate (liquid, formed during inflammation). A decrease in the pain symptom is noted approximately 1 hour after the application of the drug.
Traumeel ointment and gel are prescribed for pathologies similar to the original, but since the drug has natural basis, then contraindications to its use have differences, which for comparison are indicated in table.
| When to use Traumeel is prohibited | Contraindications for Nise gel | General prohibitions |
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Traumeel ointment and gel are allowed to be used from birth, unlike the original.
When using Traumeel, it should be applied to the skin in the same way as the original, that is, 2-3 times a day for 10 days. With severe pain, it is allowed to use the gel / ointment up to 6 times throughout the day for 14 days. When using a substitute, one should take into account the likelihood of developing side effects that are less dangerous when compared with the original.
| Backlash to Traumeel | Side effects on Nise | Common side effects |
| There are no individual side effects. When using the medication on large skin areas, only an increase in allergy is possible, other symptoms of a negative reaction do not appear. |
When applying the drug to large areas of the skin:
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Allergy in the form of itching, redness and swelling of the epidermis |
When drugs are used externally in high doses, there is an increase in side effects. But since the use of Traumeel practically does not cause the development of a negative reaction, except for allergies, no cases of overdose of these medications were recorded, unlike the original, the use of which in high doses can cause:
- increased sleepiness;
- the development of internal bleeding;
- disruption of the kidneys and organs of the digestive tract (mainly the stomach, intestines and liver);
- a sharp increase in blood pressure.
With these symptoms, a visit to the hospital is required for symptomatic treatment. You can buy Traumeel without a prescription, like Nise.
Important. Traumeel ointment and gel are recommended for combined treatment with oral medications, in contrast to the original, for which only a doctor can select a complex treatment.
Dimexide for external use
Nise-gel can be replaced with Dimexide, which is produced in the form of a gel and a solution by companies in Russia and Belarus. The active ingredient of the analogue, under the same name dimexide, has an analgesic and anti-inflammatory effect.
The therapeutic effect after applying the gel occurs in about 10 minutes and can last up to 8 hours. The fast and long-term healing effect is similar to the original, while the substitute is cheaper than Nise gel.
Indications for the use of a substitute have a slight discrepancy when compared with the original (data are presented in the table below).
| Indications for Dimexidum | Indications for Nise gel | General indications |
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Pain and swelling as a result of injury, provided the skin remains intact |
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According to the testimony of Dimexidum, it is superior to the original. But before choosing an analog gel, you should first exclude the presence of prohibitions on the use of a medication, which differ when compared with Nise gel.
| When Dimexide cannot be used | Prohibitions for Nise gel | General contraindications |
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For contraindications, Dimexide is also superior to the original.
Dimexide gel should be used 1-3 times a day for 10-15 days. It is allowed to use the product in the form of a compress (the original is strictly forbidden to be used under bandages).
When using Dimexide gel, the development of the following side effects is possible:
- itching sensation at the site of application of the gel;
- burning sensation when holding the compress for longer than the specified time;
- bronchospasm, swelling, redness of the skin and other signs of allergy to the composition of the gel;
- dryness and peeling of the skin;
- nausea due to an unpleasant smell of the drug.
For comparison, when using Nise gel, the following can additionally develop:
- diarrhea, vomiting;
- stomach ache;
- decrease in the concentration of platelets in the blood;
- the presence of blood in the urine;
- increased pressure;
- headache;
- fluid retention in the body.
In terms of the number of adverse reactions and the severity of their manifestation, Dimexide also surpasses the original. Dimexide gel, like Nise gel, is commercially available.
Important. Dimexide enhances the effect of antibiotics and pain relievers. This nuance should be taken into account if complex treatment is necessary.
Nurofen gel
Nise is a gel (cheap analogs can be chosen both Russian and imported), which can be replaced with Nurofen gel, which is produced by pharmaceutical companies in Italy and Spain.
The active ingredient of the drug (ibuprofen) has anti-inflammatory and analgesic effects, additionally helps to lower body temperature and strengthen immunity. Reduction of the pain symptom occurs in about 30-60 minutes. and can last up to 6 hours.
Indications for the use of Nurofen gel are identical to Nise gel. Contraindications to the use of an analogue have the following differences.
| When Nurofen is not used | Contraindications for Nise | General prohibitions |
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During pregnancy and lactation, Nurofen gel is allowed to be used, but only under the supervision of a doctor and with the selection of an individual course and dosage.
Gel Nurofen is recommended to be applied to the skin no more than 4 times a day for 10 days. Extension of therapy is allowed with the permission of the doctor.
When using this analogue, it is required to take into account the likelihood of developing the side effects described below:
- redness of the epidermis;
- a burning sensation at the sites of treatment with the gel;
- development of bronchospasm;
- allergic symptoms in the form of itching and rashes.
The development of more severe side effects, as with the use of the original (for example, abdominal pain, the development of edema, the appearance of blood in the urine), was not observed. In this regard, when using Nurofen gel in large quantities or for a longer time, cases of overdose development were not recorded. You can buy Nurofen gel without a prescription.
Important. Nurofen gel, like Nise gel, must be used with caution in combination treatment.
Prices
The cost of Nise gel and its analogs in Russia is indicated in the table below, taking into account price changes by region and point of sale.
| Name of the medication | Tube volume | Price range (RUB) |
| Nise gel | 20 g | 215-240 |
| Ibuprofen gel | 25 g | 35-50 |
| Traumeel gel | 50 g | 380-450 |
| Dimexide gel | 30 g | 175-210 |
| Nurofen gel | 50 g | 190-230 |
Nise gel is considered to be an effective medicine for relieving joint and lower back pain.
The advantage of the drug is not only a pronounced therapeutic effect, but also the speed and duration of pain elimination (these characteristics are not available in any analogue). At the same time, Nise also has disadvantages, among which there is not a small list of contraindications and side effects, as well as not a cheap cost.
Author: Kotlyachkova Svetlana
Video about the drug Nise
Instructions for using Nise:
