Influenza vaccine Ultrix. Reviews of doctors, instructions, manufacturer, where to buy, price

Feedback from people who made the decision deliver the vaccine from influenza, testify to the effectiveness of the formulations used in medical practice. Ultrix is ​​considered one of the safest vaccinations for the body.

Despite the fact that the vaccine in question is approved for use in strengthening children's immunity, it is recommended to put it only after familiarization with the contraindications and potential risks.

Forms of release and composition of the Ultrix influenza vaccine

The Ultrix influenza vaccine, reviews of which are controversial, is inactivated. This means that it contains purified concentrated viruses grown in chicken embryos. Their inactivation is achieved by powerful UV irradiation or the use of formalin.

The list of substances that make up influenza vaccines changes every year (in some cases, six months). This adjustment process is overseen by WHO (World Health Organization) and the Commission on Influenza Vaccines and Diagnostic Strains formed by the Ministry of Health.

Experts track trends, make predictions about the activity of specific strains, and advise manufacturers on what types of viruses to work with this year.

Ultrix inactivated influenza vaccine is supplied as a solution for intramuscular administration. The composition is packed in glass ampoules with a volume of 0.5 ml. The manufacturer's packaging involves placing 10 ampoules in 1 cardboard box.

In addition to specific types of purified and inactivated viruses (e.g. influenza type A and influenza type B), the composition of Ultrix may include merthiolate (a preservative added at a concentration of 80 to 120 μg / ml). In some cases, the manufacturer makes a vaccine without preservatives, which significantly increases its popularity in comparison with vaccines with a classical composition.

Pharmacological properties

The inactivated influenza vaccine Ultrix has an immunostimulating pharmacological effect. In other words, the considered composition, with the correct introduction and correctly calculated dosage, forms a persistent specific immunity to viruses of type A and B in a person.

After intramuscular administration of the vaccine, after 10-14 days, in the absence of a sharp negative reaction of the body to the components of the composition, active division of antibody cells occurs. This process ends when immunity to specific influenza viruses is fully formed.

The protective properties persist for 10-12 months from the date of vaccination (the specific duration is determined by the individual characteristics of human health).

Thanks to them, even if the human body encounters the flu, being already familiar with the aggressive microflora, it will overcome the virus in the shortest possible time, thus minimizing the severity of the disease being tolerated (in particular, vaccination practically eliminates the risk of damage to the brain and cardiovascular system in children due to the flu).

Ultrix is ​​considered one of the most effective vaccines, since its composition includes not only surface, but also internal antigens of influenza strains.

Pharmacodynamics and pharmacokinetics

Influenza vaccine Ultrix (reviews on the consequences of vaccination are always of interest to patients, so how the experience of other people helps to quickly decide on vaccination) creates specific immunity in 85-90% of people.

The lack of effectiveness in the formation of immunity in the rest of the vaccinated population is associated with a possible marriage of a batch of composition or individual characteristics of the body (for example, the presence of acute forms of diseases that have arisen after the introduction of the composition, or weakened organism).

It is recommended to be vaccinated against influenza annually, since the epidemiological incidence of the types of virus under consideration is seasonal. This leads to a regular change in active strains of influenza and a gradual decrease in human immunity to them.

The protection formed after the administration of a specific composition of Ultrix does not exclude the risk of damaging the body by other types of influenza viruses.

Antibodies that appear in the blood after vaccination will not be able to protect a person from even a slightly altered influenza antigen of a similar type or subtype. It is the frequent change of active antigens that determines the annual adjustment of the strain composition of vaccinations.

Indications for vaccination

It is strongly recommended to be vaccinated against influenza with Ultrix annually:

• people who have a high risk of getting the flu (for example, with a weakened immune system due to a recent acute infectious or bacterial disease);
• those who have a reasonably high risk of complications in case of infection with an influenza virus;
• persons who often suffer from acute respiratory viral diseases (more often 6 times a year);
• persons whose main occupation involves a high risk of contracting influenza due to prolonged stay in crowded places;
• people working in the fields of health care and education, transport, communal and social areas;
• police officers and military personnel;
• persons with a diagnosed somatic mental disorder, diseases of the cardiovascular system, as well as pathology of the respiratory and central nervous system;
• patients with diabetes mellitus (regardless of the type of disease) and those who have serious kidney pathologies, chronic anemia, as well as metabolic disorders;
• people with diagnosed immunodeficiency (regardless of how it was acquired).

Contraindications

Influenza vaccine Ultrix (reviews about inactivated formulations are better than about vaccinations with "live" vaccinations) is contraindicated if:

• during the previous vaccination, a person had a strong allergic reaction (from acute urticaria to Quincke's edema);
• a person has an individual intolerance to chicken protein or any other component of the composition of the influenza vaccine (if there are doubts related to possible reaction of the body, the doctor should prescribe a number of additional examinations of the patient, determining the level of his allergy and the presence of chronic diseases);
• a specific person has an increase in body temperature (not necessarily to subfebrile values) or an acute feverish state (Ultrix is ​​forbidden to enter the body at a human body temperature above 37 degrees Celsius);
• the person has a viral or bacterial disease (regardless of whether the disease is in the acute stage);
• the vaccine is planned to be administered to a woman in the 1st trimester of pregnancy (influenza vaccines are safest for the expectant mother and child in the 2nd and 3rd trimesters);
• the patient's age has not reached the minimum allowed value for the administration of the composition.

At what age can the vaccine be used?

The inactivated influenza vaccine Ultrix is ​​approved for use in the formation of immunity to the corresponding virus in children from 6 months of age. The vaccination schedule differs depending on the age of the patient.

From six months to 3 years, children are vaccinated as follows:

• if the body of a growing person has not previously encountered influenza (the diagnosis, if any, must be confirmed by laboratory), vaccination should be carried out twice in a dosage of no more than 0.25 ml with a break between the setting of vaccinations, lasting 4 weeks;
• if the inactivated influenza vaccine has already been administered once in the previous season, then in new to protect the child from influenza, it will be enough to introduce a single standard dose of Ultrix (0.25 ml);
• if the inactivated vaccine was administered once in the previous season, then in the current season it will be necessary to deliver 2 doses of Ultrix (0.25 ml each).

If a child is first vaccinated against influenza at the age of 3-9 years, then he needs to inject a dose of Ultrix equal to 0.5 ml 2 times, with an interval of at least 4 weeks. If the child has been vaccinated earlier, then a single injection of the drug within 12 months will be sufficient. (0.5 ml).

The vaccination schedule is recommended to be agreed with a pediatrician who has an idea of ​​the health status of a particular child.

Instructions for use, dosage

The dosage of Ultrix is ​​calculated individually for each patient, depending on his age and the scheme of previous vaccination.

The composition is applied according to the standard scheme:

1. Perform the necessary disinfection of work surfaces, tools, and hands.
2. Allow the ampoule with the vaccine to warm up to room temperature on its own.
3. Open the ampoule with the composition using a special sterile blade. If a cut of the ampoule neck is not provided, it is sufficient to remove the colored plastic cap or aluminum disc.
4. Using a disposable syringe, draw up the required amount of vaccine.
5. By lightly pressing the movable rod of the syringe, remove the air trapped inside.
6. Treat the area of ​​the skin through which the composition is supposed to be injected with an alcohol napkin. Ultrix is ​​injected slowly intramuscularly into the shoulder delta.
7. Remove the needle from the skin, then treat the puncture site with an alcohol wipe.
8. Dispose of used instruments and an opened vaccine vial, regardless of how much of the composition has remained intact.

The vaccination is allowed to be given only after a visual examination of the patient, the appointment of the necessary tests to him, as well as the measurement of body temperature, which should not exceed 37 degrees Celsius.

Side effects

Influenza vaccine Ultrix (reviews indicate that this vaccine, due to its safety, is most often used to vaccinate children in preschool and school institutions) extremely rarely provokes the occurrence of side reactions.

Among the possible side effects, however, manufacturers note:

• soreness at the site of puncture of the skin with a needle from a syringe used to inject the composition;
• local redness of the skin;
• slight swelling at the site of a puncture of the skin with a needle from a syringe used to inject the composition;
• temporary increase in fatigue;
• the occurrence of headache, dizziness;
• an increase in body temperature to subfebrile indicators;
• the development of symptoms of ENT diseases (pharyngitis, runny nose, and so on);
• the occurrence of allergic reactions in various forms.

In the vast majority of cases, side effects after vaccination with Ultrix do not require additional measures, and go away by themselves, 3-4 days after the intramuscular injection of the composition.

If, after the specified time, the symptoms of the post-vaccination period persist, the person should immediately contact a therapist for the prescription of medications that can normalize the condition and help the body form immunity to influenza viruses.

Overdose

There are no data on an overdose of the Ultrix vaccine.

special instructions

Specific guidelines for the use of the inactivated Ultrix vaccine include:

• despite the fact that the recommended period of vaccination is autumn and winter, it is allowed to vaccinate with more frequent cases of a diagnosed disease;
• it is strictly forbidden to inject the composition of the vaccine intravenously;
• it is not recommended to take tests for the detection of immunoenzymes in the period after the vaccination due to the increased production of lgM, as a reaction to the inactivated composition of the vaccine;
• when assessing the risks of drug administration, it is necessary to take into account the likelihood of the presence of traces of gentamicin in it;
• the introduced composition does not have a negative effect on a person's reaction and his ability to concentrate;
• in order to avoid unforeseen reactions of the body, after the vaccine has been given, the patient should be under the supervision of a doctor for half an hour;
• if the ampoule with the composition that was supposed to be used for vaccination has signs of a violation of its integrity, its use is strictly prohibited.

Drug interactions

Ultrix can be used with other inactivated influenza vaccines. According to reviews, the setting of vaccinations from different companies that have the same effect does not have a negative effect on the formation of immunity in a vaccinated person.

Despite this, when organizing vaccination according to this scheme, it is important to take into account the manufacturer's recommendations for each of the formulations used (in particular, the method of application, contraindications, dosage, the place of administration of the drug, and so on Further).

It is not recommended to inject Ultrix if the patient at that moment, for objective medical reasons, is taking immunosuppressants or glucocorticosteroids.

This combination significantly reduces the likelihood of a stable immune response to influenza strains administered by the vaccine.

Analogs

The closest analogues of the inactivated Ultrix vaccine (interchangeability is permissible) are:

Drug name	a brief description of
Vaxigripp	Inactivated influenza vaccine, split type. Approved for use in the formation of stable immunity in children from 6 months. The main disadvantage is the development of an immune response to only 3 strains of influenza. When Vaxigripp is administered to a person for the first time, the doctor should make sure that a standard set of medications is available to assist the patient in the event of an anaphylactic reaction of the body.
Influvac	Inactivated influenza vaccine, subunit type. It is approved for use in the formation of stable immunity in children from 6 months. Forms protection against influenza A and B infections. The peculiarity of this vaccine is the minimum number of contraindications and the rarity of side effects. Influvac can be administered to nursing mothers, regardless of the amount of time that has elapsed since birth.

Terms, conditions of sale and storage

Ultrix inactivated influenza vaccine is dispensed from pharmacies strictly by prescription or supplied to medical institutions directly from manufacturer (or its official distributor in the territory of a particular country) upon official request with the provision of the necessary documentation.

Keep the composition of the vaccine out of the reach of children and people suffering from mental disorders or having any type of addiction (drug or alcohol).

Freezing the contents of the ampoules is strictly prohibited in order to avoid the loss of the properties of the active components of the composition. In medical institutions, Ultrix should be stored in accordance with the manufacturer's recommendations and SanPin requirements (temperature regime - from +2 to +8 degrees Celsius).

Price

The retail price for Ultrix in pharmacies varies from 280 to 500 rubles. for 1 package. If vaccination with the inactivated composition in question is carried out in a private medical center, the cost of the procedure will be, on average, 3000 rubles. in Moscow and St. Petersburg, and about 1,500 rubles. in the regions.

The influenza vaccine must be selected not only depending on which one is available at a particular moment in availability in a medical institution, but also taking into account the reviews of real people, as well as the recommendations of a therapist or immunologist.

Ultrix, having the safest (inactivated) composition, can be used as a stimulant for the formation of an immune response to influenza strains, starting as early as 6 months. from the moment of birth.

Despite the fact that the injected drug will not be able to guarantee that the vaccinated person will not get infected influenza virus, Ultrix will be able to significantly minimize the risks associated with the consequences of the diseases.

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