Ultracain (Ultracain). Price of 1 ampoule, instructions for use, composition, where to buy, reviews

Ultracaine - popular local anesthetic, which is actively used in dentistry and other medical fields to prevent severe pain. The price of the product is affordable, especially when the patient only needs 1 ampoule. Today the drug is considered one of the most popular anesthetics, which proves its relative safety and effectiveness.

Forms of release and composition of the drug

The medication is available only in the form of a solution for parenteral administration. The solution is transparent, has a specific odor, and has no sediment. The liquid is packaged in ampoules or vials of different sizes.

The most popular are 2 ml ampoules.

, which are in an individual cardboard box in the amount of 10 pieces. The ampoules are always accompanied by instructions, which describe in detail the rules for using the medicinal solution.

In addition, you can find a product that is packaged in a kind of 1.7 ml ampoules. In an individual cardboard box, you can find instructions, as well as 10 such ampoules. This form is produced specifically for use for infiltration or conduction anesthesia in dentistry, and it is convenient to fill the ampoules into a special syringe.

As the main active component in the composition of the solution, the substance articaine is present. It is through him that the therapeutic effect is carried out. The second active ingredient is adrenaline, which enhances the effectiveness of the first.

Additionally, the composition contains water for injection, sodium metabisulfate, and sodium chloride. These ingredients have no medicinal effect. The product does not contain preservatives and other components that most often provoke allergies, which is why it is considered relatively safe for patients.

Pharmacological properties

Ultracaine (the price of 1 ampoule is available to almost every patient) has local anesthetic properties, which allows the drug to be used for different patients and with various pathological states. Most often, the tool is used in dentistry, since it affects the process of transmitting a pain impulse to nerve cells.

As a result, even minor pain sensations are eliminated, which has a beneficial effect on the patient's condition. Additionally, the medication relieves spasms that can occur against a background of strong fear. This leads to some muscle numbness in the injection site.

Many patients note that after going to the dentist it is quite difficult, and sometimes almost impossible, to control the muscles of the face on the affected side. As a rule, the action is short-term, but pronounced, which explains the high efficacy of the drug.

Pharmacodynamics and pharmacokinetics

The tool begins to actively act immediately after administration. The main ingredient of the composition is concentrated in the tissues, and blocks substances that serve as a signal for the conduction of a nerve impulse and the appearance of pain.

As a result, the injection area becomes an insensitive area where various manipulations can be performed without fear that the patient will lose consciousness from pain shock.

It should be noted that the active ingredients of the agent do not provoke increased bleeding and do not slow down tissue regeneration., which is considered an advantage over other anesthetics. Many medicines, when administered topically, slow down the formation of a blood clot, which increases the amount of blood lost and slows down the recovery process.

However, Ultracaine does not possess such properties, and also prevents the development of microorganisms on the tissues that are being interfered with. As a result, after the disappearance of the anesthetic effect, a rather rapid regeneration occurs, and the risk of complications is reduced several times.

It is due to the complex effect that the remedy is one of the most effective and relatively safe. It is worth noting that the drug does not increase blood pressure as many other local anesthetics do.

After topical application, the effect develops almost immediately and lasts for 1-3 hours, which depends on the degree of sensitivity of the patient and the pain threshold, as well as the rate of excretion of substances. Throughout the entire time, the patient does not feel pronounced discomfort, but especially sensitive people may notice minor discomfort.

The active components are concentrated in large quantities in the area of ​​administration and in a small dose enter the systemic circulation. It is almost impossible to detect substances in plasma, therefore it is impossible to identify the period that is required to reach the maximum concentration. The drug does not accumulate in tissues and organs. Well processed in the liver.

When using the product in an acidic environment, the effectiveness is slightly reduced. The elimination of the medication is carried out with the help of the kidneys. Within 5-10 hours, the components are completely removed from the body. A small part of the ingredients is excreted in the feces.

In case of disorders of the urinary and digestive systems, there is a slight slowdown in the absorption and excretion of substances from the body, which does not weaken the therapeutic effect.

Indications for use

Ultracaine is used for a variety of disorders. The affordable price of 1 ampoule of the drug allows you not to look for a substitute, but to use the original drug.

The main indications for use:

• Minimally invasive surgical interventions using endoscopic instruments. At the same time, there is no need for general anesthesia, and local anesthesia can shorten the recovery period and prevent various complications.
• Operations on the nasopharynx. When removing tonsils, adenoids, or removing purulent contents from the maxillary sinuses, local anesthesia may be required to help the patient cope with the discomfort more easily.
• Dental manipulations, involving the extraction of teeth, the installation of a seal or crown, an implant. Today, such interventions are carried out quite often. Often, patients ask the doctor to immediately perform manipulation on several units, which, in the absence of anesthesia, can lead to complications.
• Cleaning of deep purulent wounds of large sizewhen the patient is unable to withstand the pain. For this purpose, the medicine is used less often, but sometimes it is necessary, since severe pain can lead to complications in the patient.
• Blocks with severe pain in the spinal column. In this case, the remedy is used in combination with other medicines that increase the effectiveness and at the same time relieve the inflammatory process, which allows you to get rid of pain for a long time. As a rule, the remedy is supplemented with hormonal medication and B vitamins. Such blockades are carried out with intervertebral hernias at the initial stage, osteochondrosis, osteoarthritis, as well as other pathological conditions.

Often, the tool is used in cosmetology during various procedures aimed at correcting the contour of the face and lips.

Contraindications

The drug is not prescribed if an intolerance to its components is detected, as well as a history of allergies to such drugs. Contraindications include anemia that develops against the background of cyanocobalamin deficiency, as well as severe renal failure.

With cirrhosis of the liver, acute hepatitis and liver failure, the drug is not prescribed. It is also not used for severe angle-closure glaucoma, atrial fibrillation and advanced tachycardia. The last symptom is usually a consequence of the advanced course of heart pathology, therefore, the use of a medicine can aggravate the condition and lead to complications.

You can not prescribe a medicine when diagnosing a severe form of bronchial asthma, accompanied by an allergy to drugs from the group of non-steroidal anti-inflammatory, sulfonamides. The use of the medication can provoke severe complications and increased seizure frequency.

Relative contraindications include a severe course of arterial hypertension, as well as anemia, hyperthyroidism, in which there are minor disorders of the thyroid gland. In addition, the drug is used with caution in type 1 diabetes mellitus, as well as for the treatment of elderly patients.

At what age can the drug be used?

Ultracaine (the price of 1 ampoule may differ in different pharmacies) is prescribed only to patients over 4 years old. If it is necessary to carry out local anesthesia, patients under 4 years old use external agents in the form of a gel or spray.

Instructions for use, dosage

In most cases, the remedy is used by specialists in a polyclinic or hospital. In dentistry, it is used most often. Before the extraction or filling of teeth, an adult is injected no more than 1.5 ml into the palatal suture.

This dosage is sufficient to achieve an anesthetic effect. If necessary, a repeated dose can be administered no earlier than 6 hours after the last injection. Such a need is rare. It is allowed to administer 1.5 ml of the drug daily, when the patient visits the dentist for several days, for example, if it is necessary to treat several units at once.

Children from 14 years old are injected from 0.5 to 1 ml of the drug, if such a need arises, repeated administration on the same day is contraindicated. For children from 4 to 14 years old, the drug is administered very rarely, but the dosage for them does not exceed 0.5 ml per day.

If it is necessary to carry out infiltration anesthesia, the patient is injected subcutaneously from 5 to 10 ml of the agent, depending on the extent of the affected area and the level of the pain threshold. This will relieve a person from pain for 1-3 hours and carry out all the necessary manipulations.

It is worth noting that when injected, a point technique is used, according to which the affected tissues are anesthetized pointwise. That is, a small amount of the agent is injected into several places around the perimeter of the focus, which helps to prevent the appearance of discomfort in the area of ​​manipulation.

This method is used quite often. If a blockade is required in the area of ​​the shoulder blades or in another place where severe pain associated with pathologies of the spine, 1-2 ml of the drug is taken into the syringe, after which a hormonal drug is added to it and vitamin. This mixture is injected into the area of ​​greatest pain, which is determined by palpation.

Such a blockade is carried out no more than 1 time in 3-6 months, but the procedure is considered very effective. The tool is also used for other manipulations, the dosage in each case is determined individually. The drug is not used for long courses.

Side effects

Ultracaine (the price of 1 ampoule may depend on the dosage of the active ingredient) can provoke complications, despite its safety and the minimum amount of active ingredients.

Organs and systems	Most common complications
Nervous and peripheral system	Cramps and tremors of the limbs, headaches and dizziness appear quite often when using the medicine. In addition, patients may be disturbed by insomnia, pathological limb mobility. Sometimes fainting is possible, but this complication is not so common.
Digestive tract	When using the solution, nausea and vomiting may occur. Some talk about diarrhea, only in exceptional cases persistent constipation develops. Quite often, patients talk about intense thirst, poor appetite and pain in the stomach.
Sense organs	With single or repeated use, it is possible to develop diplopia, that is, double vision in the eyes. If the patient does not inform the doctor about the disorder, the condition turns into visual impairment. As a rule, the symptom disappears after stopping the use of the drug, but it can persist for several days.
Vessels and hearts	Tachycardia and arrhythmia during treatment develops in most cases in patients who suffer from chronic heart disease. Some patients have a decrease in blood pressure and heart rate, which is considered a rare complication.
Skin	Allergy to the drug manifests itself in the form of a rash and itching of the skin. Often, patients notice the appearance of foci of flaking and redness.

In case of violation of the technique of introduction or non-observance of the rules of asepsis and antisepsis, it is possible to develop local negative manifestations in the form of swelling and hyperemia of tissues, as well as pain.

The severity of negative reactions depends on the age of the patient and the dose of the drug administered. If complications appear, it is worth abandoning the remedy and undergoing a course of symptomatic treatment.

Overdose

When used correctly, an overdose of the drug is unlikely. However, such cases have been recorded. At the same time, the patient's condition is aggravated, the severity of all negative reactions increases.

The headache worsens, there is repeated vomiting and frequent loose stools. In addition, severe convulsions are observed. The patient cannot perform even minor hand manipulations, since he has a tremor.

The most dangerous manifestation of an overdose is a critical decrease in pressure and the development of shock a condition in which the risk of death increases, respiratory depression and other violations.

In case of an overdose, cardiac arrest, as well as severe bradycardia, is possible. As a rule, when using a large dose of the drug, there are no manifestations of allergies, since disorders of the vessels and the heart come first. The appearance of signs of an overdose is considered a reason for refusing further administration and prescribing symptomatic treatment.

The drug does not have a specific antidote, therefore, treatment depends on the severity of the symptoms, as well as the age of the patient, the dosage of the drug that provoked the disorder.

special instructions

Ultracaine (the price of 1 ampoule may differ in different regions) with local infiltration anesthesia is used after preliminary measurement of all indicators.

The patient's pulse, blood pressure and body temperature are measured. The anesthesiologist calculates the heart rate, and also interviews the patient in order to identify cases of allergies in history. This eliminates complications.

The procedures are always carried out in a medical institution. It is categorically contraindicated to use the solution at home. When swelling and pain occurs at the injection site, external agents are used to help eliminate discomfort.

The drug is not injected directly into the inflamed tissues, it is also prohibited to use it for intravenous injections.

The drug is not prohibited to use during pregnancy and lactation, which is associated with minimal penetration into the systemic blood flow and the lack of the ability of the active component to overcome the placental barrier or penetrate into the chest milk.

Drug interactions

The medication cannot be used simultaneously with drugs that contain the same active ingredient. This can provoke an overdose. Do not combine the drug with some antidepressants and antihypertensive medications.

It is dangerous to combine the solution with non-selective beta-blockers, since the risk of developing negative symptoms from the blood vessels and the heart is significantly increased. When using the solution, it is worth remembering that it enhances the effect of other anesthetics. In each case, the doctor decides on the combination of one or another remedy.

Analogs

In some cases, Ultracaine must be replaced with another agent.

There are several analogs that have the same properties:

• Markain - local anesthetics based on bupivacaine, which has a pronounced effect. It is noted that the agent is 4 times stronger than Lidocaine, which makes it possible to use it for spinal anesthesia and when performing minimally invasive soft tissue operations.
• Lidocaine - the agent, which is available in the form of a spray and solution, is often used for the purpose of local anesthesia. It does not possess such pronounced properties as Ultracaine, but in some cases it can be used as a substitute.

  

• Ubistezine - a drug based on articaine and epinephrine, which is often used for the purpose of local conduction or infiltration anesthesia. It has pronounced properties, rarely provokes complications, provided it is used correctly.
• Scandonest - a solution based on mepivacaine. Contains another active ingredient, but has the same therapeutic properties, it is often used for local short-term pain relief in dentistry and other fields of medicine.

Analogues are used only as directed by a doctor and in the absence of contraindications. Many drugs with a similar effect can provoke complications.

Terms, conditions of sale and storage

The sale of the product is carried out by prescription from a doctor. The solution can be stored for 5 years. At the same time, it is important to limit access to children and direct sunlight.

The production date is indicated on the packaging. It is categorically contraindicated to freeze the solution, as well as to use it after the expiration date.

Price

The cost of the medicine is approximately 50-60 rubles. for 1 ampoule. In different pharmacies and regions, the price may differ.

Ultracaine is a local anesthetic with pronounced properties, which is relatively safe. The price of the medicine for 1 ampoule is affordable, so in most cases the patient can afford such local anesthesia.

Video about Ultracain analogs

Indications for the use of ampoules of Lidocaine: