Diflucan (Diflucan) suspension for children, men, women. Instructions for use, analogues are cheaper, reviews, price

Diflucan - antifungal suspension which has pronounced therapeutic properties and is used to treat children of different ages. The drug helps to cope with the severe manifestations of various diseases of fungal origin, is considered universal for patients of different ages due to the content of an effective acting substances.

Indications for use

The medication is an effective antifungal agent that is used in the treatment of various mycotic pathologies at different stages of development. The drug has pronounced antifungal, anti-inflammatory properties, helps to normalize the intestinal microflora and prevents the development of acute dysbiosis.

The main indications for prescribing a medication:

• The recovery period after undergoing a course of antibiotic therapy. In this case, the patient usually develops diarrhea and dehydration.
• Infections of the mucous membranes and organs of the digestive tract, provoked by the multiplication of a fungus from the genus Candida.
• Prevention of the development of dysbiosis with prolonged use of not only antibiotics, but drugs from other groups.
• The development of bacterial vaginosis in women of different ages. In this case, the agent can be used in the acute stage or during the transition of pathology to a chronic form.
• Diagnosing a fungal disease of the skin. In this case, the greatest efficiency is achieved with treatment at the initial stage.
• Onychomycosis, that is, a fungal infection of the nail plates of the hands or feet.
• Immunodeficiency states during HIV infection. Moreover, patients often develop dysbiosis and other fungal pathologies as a result of a strong weakening of immunity.
• Candidal stomatitis in children and adults.

Such conditions can occur as an independent disorder or in the form of a concomitant complication in other diseases, therefore, the remedy is also used as part of a comprehensive treatment.

Compound

Diflucan is a suspension for children that contains fluconazole as the main active ingredient. It is this component that has an antifungal effect and is effective against many fungi that can infect the internal organs and external tissues of a person.

Additionally, auxiliary ingredients can be found in the composition of the product:

• Sodium benzoate.
• Citric acid.
• Titanium dioxide.
• Xanthan gum.
• Sodium citrate.
• Orange flavor.

The excipients do not have a therapeutic effect, but the aroma gives the product a pleasant citrus aroma, which makes it easier for children to use.

In what form is it produced

The medicine for children is only available in powder form, which is used for the preparation of an oral suspension. 1 ml of the prepared product contains 10 or 40 mg of fluconazole, which facilitates dosing.

The powder is white, is in a polyethylene bottle, dissolves well. After dissolving, you can get 35 ml of a suspension with a pronounced orange aroma, sweetish taste.

The suspension has a white or almost white color; when used, it can be noted the presence of very small grains, which remain even after dissolution. Each bottle of powder is placed in a cardboard box, which also contains instructions for correct use and a measuring spoon for easy dosing.

In addition, the agent is available in the form of an intravenous solution, which is prescribed only for adults. 1 ml of such a solution contains 1 or 2 mg of the active substance. On pharmacy shelves, you can find capsules for oral use, packaged in blisters. They are also used for adults, 1 capsule contains 50, 150 or 100 mg of active ingredient.

The cost of the suspension is approximately 500 rubles. per bottle. The price of the solution and capsules ranges from 300-600 rubles.

Pharmacodynamics

Diflucan is a suspension for children and adults with pronounced antifungal properties. After ingestion of the drug, it is absorbed in the small intestine and the active ingredient penetrates into the blood.

Fluconazole affects the synthesis of important components in fungal cells, which leads to disruption of metabolic processes and their gradual death.

It should be noted that the active ingredient is active against mold and yeast., helps to get rid of yeast-like organisms. A wide range of antifungal activity allows the drug to be used in various pathological conditions.

The active substance not only weakens the fungi, destroys them, but also prevents repeated damage to the mucous membranes, organs and tissues. As a result, the likelihood of complications and the spread of infection to healthy tissues is reduced.

Additionally, the active ingredient is active against fungal enzymes. It also increases the effectiveness of the medication and helps prevent complications from other organs.

Pharmacokinetics

After taking the suspension inside, it is actively absorbed in the digestive tract. The active ingredient spreads through the systemic circulation and has an antifungal effect. Most of it is concentrated precisely in the area of ​​accumulation of fungi, which allows you to get rid of acute manifestations of the disease in a short period of time.

The maximum concentration of the ingredient in the blood is found 30-90 minutes after oral administration. The agent is very well absorbed in the digestive tract, and its main component binds to blood plasma proteins by 91%, which explains the high bioavailability.

Good absorption and binding to plasma proteins helps the drug to have a rapid therapeutic effect. That is why the suspension is used more often than other medicines for the treatment of children, despite its high cost. One of the advantages of the remedy is the absence of the effect of food intake on its bioavailability and effectiveness.

The effect of the medication persists throughout the day after a single dose, which is also considered advantage, since there is no need to re-take the medicine if therapy is being performed an adult.

It is worth noting that the active substance of the product penetrates well not only into organs and tissues, but also into the skin., nail plates and cerebrospinal fluid. That is why the drug is effective for systemic and local fungal pathologies.

A sufficient amount of fluconazole is found even in the patient's sweat glands. The processing of the active substance is carried out in the liver, but it is excreted unchanged by the kidneys. The withdrawal period does not depend on food intake and other factors, it takes up to 2 days. Only with severe damage to the mucous membranes of the small intestine, the absorption and evacuation of the active ingredient is somewhat slowed down.

Application

Diflucan in different dosage forms is used for the treatment of adults and children. The latter is usually prescribed a suspension in an individual dosage depending on the condition and age.

For children under 18

Suspensions are prescribed for patients under 18 years of age. It must be prepared immediately before the first use. To do this, cool the representatively boiled water, add 24 ml to the bottle with powder. For accurate dosage of the amount of water, a conventional disposable sterile syringe can be used.

After adding water, the bottle must be shaken thoroughly to achieve good dissolution. It is worth remembering that the bottle is also shaken thoroughly before each dose. There are no restrictions on admission for children, that is, the medicine is used at any age. However, infants and children under 1 year of age should be given the medicine under medical supervision.

The dosage is determined depending on the body weight. For 1 kg of the child's weight, there should be 3 mg of the active ingredient. If a suspension is used with a dosage of 10 mg per 1 ml, then only 1 ml of the drug is allowed for the newborn per day. Reception should be repeated once a day.

The duration of treatment is determined by the pediatrician in each case individually. Usually 3 days of treatment are enough, but in severe cases, the course can be extended.

It should be noted that for children with liver and kidney pathologies, the dosage is determined individually and only by a doctor. With generalized mycoses, the dose per 1 kg of body weight can be increased to 12 mg. However, it is worth remembering that her parents cannot independently increase her without first consulting a doctor.

For adults

Adults are prescribed capsules or solution for intravenous administration. The regimen and dosage depends on the degree of neglect of the disease.

Disease	Scheme of application and dosage
Mild yeast infection in women or men	With such a disease, the patient is prescribed from 150 to 200 mg of the drug once, that is, it is necessary to take 1 or 2 capsules, depending on the dose of the active substance. Reapplication is not required as this dose is considered effective.
Chronic genital candidiasis	In chronic candidiasis, women and men are prescribed 150-200 mg of the drug. It is necessary to take this dose once a month for 6 months. As a rule, such a course helps to get rid of the manifestations of the disease.
Generalized fungal pathologies	For such diseases, men and women are usually prescribed a solution for parenteral administration. The procedures are carried out in a hospital, the patient is injected with 50 or 100 ml of solution using a dropper 1 time per day. Treatment can last from 7 to 21 days, depending on the severity of the symptoms. In exceptional cases, therapy is required for 4 weeks
Fungal infection of the skin and nails	The daily dosage for such lesions is 400 mg. It is allowed to use solution or capsules. The second option is considered more convenient for home use. The course lasts from 1 to 4 weeks and is determined only by a doctor

At home, capsules are usually used, which are taken 1 time per day. However, in each case, the doctor individually decides which dosage form to choose for a particular patient.

For pregnant

The drug is not used during lactation and childbearing. Experts have not conducted studies that would confirm the danger of using the drug during this period, but there is no data on the safety of the use.

That is why medication for pregnant and lactating women is rarely prescribed and only if there are strict indications.

For the elderly

The treatment regimen for elderly patients does not differ from that used for adults. Despite this, doctors monitor the condition of patients, which avoids complications.

Elderly patients are strongly advised not to use the medicine at home without a preliminary examination.

Contraindications

Diflucan is a suspension for children and adults, which is not prescribed when an intolerance to the components of the composition or a tendency to similar manifestations is detected. Do not use the medicine for severe renal and hepatic insufficiency with severe organ disorders.

Contraindications include the following conditions:

• Blood pathologies, accompanied by a violation of the formation of its main cells.
• Diseases of the stomach and intestines in the acute stage. With colitis, peptic ulcer, the use of a medicine can provoke complications. In addition, you should not take the remedy for exacerbation of pancreatitis.
• Internal bleeding with damage to the mucous membrane of the digestive tract.
• Tendency to gastrointestinal bleeding.
• Chronic kidney pathology in the acute stage.

The drug is not prescribed for pregnant and lactating women, as well as children who suffer from severe kidney disease. This is due to a violation of the process of removing the processed component from the body. For elderly patients, the medicine is also prescribed with caution, but according to the standard scheme.

Overdose

When taking large doses of medication without a doctor's prescription, an overdose may develop. The condition is accompanied by severe disorders of the nervous system. Patients report severe headache, dizziness and weakness.

The patient's sleep is disturbed, there is rapid fatigue and depressive disorders, which lead to the development of pathologies of internal organs. In severe cases, the appearance of hallucinations and the development of a paranoid state is observed. In this case, the patient becomes aggressive or apathetic, does not control his actions.

When interviewing such a patient, you can see that he is not able to answer simple questions and talk about his feelings. In many cases, the patient cannot even give his name and describe the events preceding the development of such a disorder.

Overdose may be accompanied by repeated vomiting, diarrhea. The patient's skin becomes pale, moist and cold to the touch, there is a decrease in blood pressure and muscle weakness.

If at this stage the patient has not received help, the symptoms are aggravated. An overdose threatens not only the health, but also the life of the patient, therefore, if its signs appear, you should immediately visit a doctor.

In a hospital setting, the patient will undergo a gastric lavage procedure, and also prescribe symptomatic therapy in order to eliminate the manifestations.

Side effects

Violation of the instructions can lead to the development of complications from the internal organs and systems.

The most common adverse reactions:

• Sleep disturbance.
• Decreased appetite with a simultaneous increase in thirst.
• Pain in the stomach, intestinal colic develops quite rarely.
• Dizziness and headache, aggravated by exertion.
• Emotional instability, irritability and a sharp change in mood in one direction or another.
• Nausea and bouts of vomiting that are not associated with food intake and do not relieve the patient's condition.
• Development of a toxic form of hepatitis.
• Exacerbation of chronic pathologies of the digestive system.
• Decrease in the number of platelets in the blood.
• Jumps in blood pressure in one direction or another, tachycardia. Usually, symptoms develop in elderly patients, when examining the cardiogram, you can see abnormalities that disrupt the work of the heart.

Often, negative reactions are manifested in the form of allergies. A rash appears on the skin, itching and burning are noted, which intensifies when scratching. As the condition progresses, the symptoms worsen, the development of angioedema or acute urticaria is possible.

Such complications can threaten the patient's life, therefore, require complex treatment. If complications appear, it is important to stop taking the drug and visit a doctor in order to receive therapy.

Drug interactions

Diflucan is a suspension for children and adults that is not used in combination with other antifungal agents, even if they contain another active ingredient.

Do not use the medicine in combination with products containing aminophylline and its analogs, as this increases the risk of complications. The drug is prescribed with caution in the treatment of cardiac glycosides, antihypertensive agents.

It is allowed to combine the drug with oral contraceptives, but it should be borne in mind that the concentration of the latter in the blood increases as a result of exposure to fluconazole. Some diuretics, for example, hydrochlorothiazide, slows down the elimination of the suspension components from the body. But loop diuretics speed up the elimination of ingredients.

It is allowed to use the medicine simultaneously with sedative, vascular and nootropic medicines. In each case, prior consultation with a specialist is required before using any medication in combination with Diflucan.

Storage conditions and periods

It is important to store the medication away from children, as well as direct sunlight, especially if a suspension is used. The drug has a maximum shelf life of 3 years. However, after preparing the suspension, you can store it in a cool place for no longer than 2 weeks.

It is strictly forbidden to take the suspension after storage for more than 2 weeks, as well as to prepare it if the expiration date of the powder in the vial has expired.

Conditions of dispensing from pharmacies

Today, pharmacies in different regions dispense drugs only with a prescription from a doctor. This eliminates the possibility of self-medication, especially if it is necessary to use it for children.

Analogs

In some cases, the use of the drug is not possible.

There are substitutes with similar therapeutic properties:

• Fluconazole - capsules and tablets that contain the active ingredient of the same name and help to cope with various fungal diseases. The drug is prescribed for adults and children from 4 years of age. The first take the medicine 1-2 tablets per day for 3-7 days. For children, the initial dosage is ½ tablet and increases depending on age and body weight. They usually take the remedy for no longer than 10 days.
• Difluzol - capsules for oral administration, which also contain fluconazole as the main component. They are prescribed for fungal pathologies for children from 6 years old and adults. The daily dosage for patients is 1 capsule, sometimes an adult needs to consume 2 capsules per day at once. As a rule, a single dose is sufficient, but it is possible to extend the course up to 1-2 weeks, depending on the patient's condition.

Analogs usually have a lower cost, but have the same properties.

Diflucan is a popular and quite effective suspension. It is used to treat children and adults with various diseases of fungal origin, it is safe and, if all the rules are observed, it rarely provokes complications.

Video about the active substance of Diflucan

About fluconazole: