Magnesium diasporal 300. Price, instructions for use, analogs, where to buy, how to take, reviews

The intake of Magnesium diasporal 300 is justified in all cases of deficiency magnesium in the body. The price of the drug does not allow it to be classified as the most affordable. However, the course use of this tool, according to reviews, allows you to achieve good clinical results.

Composition, release form

The official international name for this medication is Magnesium diasporal 300. The drug is produced by a leading German pharmaceutical company.

Unlike analogs intended for use with a lack of magnesium, this agent has a specific form release is a powdery granular mixture of a yellowish tint used in the preparation of oral solution. The granules are packaged in sachet bags weighing 5 g.

1 carton pack can contain 20 or 50 of these mini-packs, connected by an easily torn seam. Each 5 g sachet contains a whole complex of substances, among which, in addition to magnesium citrate (1830 mg, corresponding to 295.7 mg of magnesium), it is worth noting riboflavin, sucrose, sodium bicarbonate.

Magnesium diasporal 300, the price of which exceeds the cost of analogues, is an officially registered medication. It is not a dietary supplement. The drug belongs to the pharmacotherapeutic group A.12.C.C Magnesium preparations.

Selling features

You can buy the drug in stationary pharmacy chains or online pharmacies.

However, every user should know that today the sale of medicines through the worldwide network is prohibited.

You can find and buy Magnesium Diasporal 300 without leaving your home using services that provide exclusively search and booking services. But the delivery of the drug itself, according to the law, cannot be carried out by third-party companies, so you will have to pick up the medicine from the pharmacy yourself.

This restriction does not apply to cosmetic products, dietary supplements, vitamin and mineral complexes and other products that do not belong to the category of medicines. They can be sold over the Internet and delivered to the customer.

Thus, reserve Magnesium Diasporal 300 through an online resource and receive the drug in pharmacy with a convenient location, you can, but legally order it with home delivery - impossible. Also, you should not turn to shadow firms, since in this case there can be no talk of any guarantees of quality and health safety.

The cost of a package with 20 sachets is in the range of 825 - 1,022 rubles. Each pack contains an annotation to the drug from the manufacturer.

Mechanism of action

The pharmacological properties of the drug directly depend on the participation of magnesium in biochemical reactions. It is an indispensable element present in all cells and tissues. This substance must be contained in the body in a certain amount in order to maintain cell functionality, participate in metabolism, contribute to the production and maintenance energy reserves.

Thanks to magnesium ions, which are calcium antagonists, increased neuronal excitability, neuromuscular transmission of impulses is normalized, the course of enzymatic reactions. Magnesium citrate is easily absorbed and tolerated by patients, and rarely causes allergic reactions.

The daily requirement for an adult in magnesium is about 300 mg. Almost the same amount is contained in 1 mini-package of Magnesium diasporal 300, which, entering the body, stimulates the production of choline and cholinesterase, and takes part in other enzymatic processes.

Magnesium citrate is required primarily for energy supply to muscle tissue. In fact, this component directly performs the function of a membrane protector, which helps to stabilize the level of phospholipids in the cell membrane.

Magnesium citrate prevents excess calcium deposits from forming. In order to regulate muscle excitability and prevent the flow of calcium ions through the presynaptic membrane barriers in the central nervous system, the concentration of neurotransmitters decreases.

The pharmacokinetic properties of magnesium directly depend on the amount in which it enters the body. The main part of the substance is absorbed into the bloodstream through the walls of the small intestine, while its volume will be proportional to the serum levels of magnesium in the blood.

In patients suffering from malabsorption syndrome, as well as in those who abuse foods high in vegetable or animal fats, the absorption of magnesium is minimal.

Magnesium diasporal 300, absorbed into the blood, is excreted from the body through the urinary system, sweat glands and bile. The part of the drug that is not absorbed into the blood enters the large intestine and has a mild laxative effect.

The rate of filtration and excretion of magnesium by the kidneys is associated with the level of this substance in the plasma and the value of the glomerular process of blood purification. Normally, serum contains approximately 1% magnesium citrate, which equals 0.8–1 mmol / L. Not more than 50% of the specified amount reacts with albumin.

Indications for use

Magnesium is involved in many biological processes and is responsible for several hundred chemical reactions. For example, adenosine triphosphate, which is an important chemical compound for ensuring uninterrupted nutrition of cells, consists of 30% magnesium salts.

Since between the concentration of magnesium in the blood serum and its content in bone and muscle tissues, a kind of balance, to draw a conclusion about the existing deficiency of a given substance in the body by only one result of laboratory analysis impractical.

The lack of magnesium can be judged by the presence of the corresponding symptoms, indicating impaired neuromuscular conduction:

Organ system	Symptoms	Possible complications
central nervous system	Headaches, frequent dizziness, lightheadedness, decreased concentration, irritability, aggression.	Stroke, arteriosclerosis, depression.
Muscular apparatus	Neck pain, twitching of the muscles of the face, thoracic and lumbar spine, neck and shoulder collar, cramps of the calf muscles, feet, toes, hands.	Chronic fatigue syndrome, fibromyalgia, osteoporosis.
The cardiovascular system	Arrhythmia, tachycardia, hypertension.	Ischemic heart disease, atrial fibrillation, development of heart failure, sudden death.
Digestive system	Spasms in the stomach, duodenum and colon, nausea, vomiting, stool disorders.	Diabetes, autonomic disorders, abdominal pain of unknown etiology.
Kidneys and urinary tract	Cramping pain during urination.	Kidney and bladder stones, congestion.

Magnesium diasporal 300 (the price of the drug is indicated above) is recommended for use if available confirmed magnesium deficiency, which is manifested by one or more of these symptoms in the table. If, after a month of using the drug, no improvement has occurred, further taking the medication does not make sense.

Contraindications

The need for magnesium for the vital functions of the body has been confirmed by many laboratory studies. However, it would be wrong to consider drugs based on this substance completely safe. They, like a number of other medicines, have contraindications.

An absolute ban on the use of Diasporal 300 Magnesium occurs in the following cases:

• with increased individual sensitivity to magnesium citrate;
• with severe forms of renal failure and creatinine clearance less than 30 ml / min;
• with atrioventricular block;
• with myasthenia gravis;
• with an excess of magnesium in the blood serum.

For persons suffering from diabetes mellitus, Magnesium Diasporal 300 is contraindicated due to the presence of sucrose in its composition. Also, this drug is not prescribed for children under 12 years of age. It is necessary to use the product on the recommendation and under the supervision of a doctor.

Side effects

The drug is capable of provoking adverse reactions in the body. Taking Magnesium diasporal 300 sometimes leads to temporary disorders of the central nervous system, which appears as weakness, loss of strength, and apathy.

Such side effects occur, as a rule, as a result of prolonged or uncontrolled use of the drug. It is recommended to suspend further use of Magnesium Diasporal 300, and it will be possible to resume taking the drug in a lower dosage after stabilization of health.

Sometimes patients develop allergies to magnesium medications. In this case, we are talking about the reaction of the immune system to the main or auxiliary components. Most often, allergies are manifested by a skin rash, mild itching and swelling. After discontinuation of the drug, the symptoms go away on their own.

In the first days of using Magnesium diasporal 300, some patients, judging by the reviews, observe changes in the gastrointestinal tract, expressed by diarrhea, flatulence, nausea, and abdominal pain.

Such undesirable reactions to the drug, although they bring temporary discomfort, are still not a reason for a categorical refusal to use it. If it is necessary to select an analogue, the patient should consult a doctor.

Overdose

If for a long time the amount of magnesium entering the body exceeds the daily requirement for this substance, the patient may experience symptoms of an overdose.

The maximum allowable amount of magnesium is considered to be 310-420 mg. Pregnant and lactating women, as well as those involved in professional sports, experiencing regular physical activity, the need for any trace elements increases by 20-25%.

With the course of magnesium intake, the full functioning of the kidneys is of great importance. In the case of a slight overabundance of a substance that enters the body by the oral route, no symptoms appear in a person with healthy kidneys.

In case of an overdose that leads to an increase in the level of magnesium in the blood serum, the following symptoms and complications occur:

• vomiting;
• nausea;
• drop in blood pressure readings;
• bradycardia;
• depression of the central nervous system;
• dulling reflexes;
• lack of urination;
• breathing disorders, up to a complete stop;
• coma;
• death.

Thus, an excess of magnesium can be fatal if the necessary actions are not taken in a timely manner.

Rescue therapy involves:

• intravenous administration of calcium - a magnesium antagonist, which partially neutralizes its effect;
• subcutaneous and intramuscular injections of a cholinesterase inhibitor;
• drip injection of sodium chloride 0.9% for blood cleaning.

Patients with a history of renal failure undergo hemodialysis as a matter of urgency.

Method of administration and dosage

Magnesium diasporal 300 in granules is used orally. The drug, about the price of which there is often indignation, is diluted with water and the resulting liquid solution is drunk. 1 sachet contains the recommended dose of magnesium for adult patients, so there is no need to divide its contents over several days of treatment.

Before use, the granules from 1 sachet are dissolved in 100 ml of drinking water, non-hot tea or juice. The average course duration is 1 month. If necessary, after 2-3 months, taking the drug can be repeated with the permission of the doctor. As soon as the level of magnesium in the blood reaches normal values, further intake of the drug must be abandoned.

special instructions

It is necessary to use the medication strictly according to the instructions. It is impossible to arbitrarily increase the dosage recommended by the manufacturer. However, in some cases, adjustment of the therapeutic dose is allowed in agreement with the doctor.

The dosage is calculated based on the established daily norms: about 300 mg should enter the human body magnesium daily (the specified amount of need also includes those substances that are contained in products power supply).

However, the systematic use of alcoholic beverages, strong coffee, tea, laxatives, increased physical activity increase this need.

Magnesium diasporal 300 (the price of the drug deserves special attention) is undesirable for people with genetic disorders accompanied by fructose intolerance, glucose-galactose malabsorption or deficiency sucrose-isomaltose.

Also, restrictions apply to patients who are prescribed a dietary salt-free table, since 1 package of this medication contains about 40 mg of sodium.

If the patient has a deficiency of magnesium and calcium at the same time, it is impossible to replenish the missing substances with the parallel use of such drugs. First, you need to undergo treatment with Diasporal 300 Magnesium, and then start taking medications and dietary supplements with a high calcium content.

Precautionary measures

Diasporal magnesium 300 does not affect the reaction rate and the quality of control of various mechanisms and vehicles. The drug has no effect on psychomotor functions, does not change the patient's cognitive behavior.

For patients with moderate renal insufficiency, the drug is indicated in the minimum dosage due to the risk of developing hypermagnesemia. At the same time, for pregnant and lactating women, this drug can be used as directed by specialists.

Numerous clinical experiences confirm the absence of a direct relationship between medication intake and the development of intrauterine fetal malformations, but Magnesium Diasporal 300 is only recommended if the potential maternal health benefits outweigh the developmental risks unborn child.

The active substance passes into breast milk through the bloodstream, therefore, in order to avoid oversaturation of the child's body with magnesium, lactation must be suspended before starting treatment.

Drug interactions

It is possible to combine Magnesium Diasporal 300 with other medicines, however, planning to take other drugs in parallel, it is imperative to inform your doctor about this. So, for example, the effect of muscle relaxants increases when combined with magnesium salts. Aminoglycosides, diuretics, antacids act in the opposite way: they remove magnesium from the body, provoking its lack.

If it is necessary to undergo complex treatment, incompatible medications can be used, but subject to a 3-hour interval between taking each of them.

This will avoid their interaction and will not interfere with full absorption. Magnesium preparations have a weakening effect on indirect anticoagulants, while calcium salts and phosphates reduce its absorption in the gastrointestinal tract.

Storage conditions and periods

Special conditions for storing Magnesium Diasporal 300 are not required. Sachets must be kept in sealed containers, protected from direct sunlight. The optimum temperature for this medication is room temperature, not higher than 25 ° C. The drug remains usable for 3 years from the date of release.

Analogs

According to the chemical formula and principle of action, Diasporal 300 can hardly be called a unique drug. It is distinguished from other drugs in this group by the form of release and the relatively high cost. In case of drug intolerance, you can find a full replacement for it and continue therapy.

Magnelis B6 Forte

This product is a combination of magnesium citrate and vitamin B6. The drug is produced in the form of tablets, each of which contains 618 mg of magnesium, corresponding to 100 mg of easily digestible magnesium. 1 package of Magnelis B6 Forte contains 60 tablets.

The main indication for its use is a lack of magnesium, which is the cause of various functional disorders:

• muscle spasms;
• tachycardia;
• depression.

It has the same application restrictions as other magnesium-containing products. Unlike Magnesium diasporal 300, which is recommended to be taken once a day, Magnelis B6 Forte is used daily in 3-4 tablets. In this case, the dosage can be increased or decreased according to indications. The average price of a medicine in pharmacies is 550-600 rubles.

Magnerot

In the composition of this drug, the main component is not magnesium citrate, but orotic acid, which has almost the same structure as most vitamins. Magnerot is prescribed to patients not only for the purpose of replenishing magnesium reserves in the body, but also as a compound that increases the bioavailability of metals.

The medication is produced in tablet form with a dosage of 500 mg of magnesium orotate. Most often, the medicine is prescribed to people suffering from heart disease. Magnerot is prescribed to patients who have had a heart attack, with ischemic disease and chronic myocardial insufficiency, arrhythmias, atherosclerotic vascular lesions.

The standard regimen for Magnerot's use is 2 tablets three times a day. 1 package contains 50 tablets and it costs more than 650 rubles. Magnerot is an expensive drug. To undergo the recommended 30-day course of treatment, you will have to spend about 2500 rubles. Another drawback of the drug is the presence of additional contraindications, in comparison with Magnesium diasporal 300 (cirrhosis of the liver and urolithiasis).

Magne Express

Diasporal 300 magnesium, the price of which is within 1000 rubles, loses by this criterion: the cost of a Magne Express package with 20 sachets is approximately 500-550 rubles.

This drug is a complex of pyridoxine hydrochloride and magnesium citrate. Both components enhance the action of each other, helping to restore the balance of important trace elements in the body.

Magne Express is sold in sachets with granules for oral administration. Unlike Magnesium Diasporal 300, they should not be diluted in water, but simply absorbed. Take 2 sachets per day with meals. By the way, the granules have a pleasant taste and aroma of exotic fruits.

Magnesium preparations such as Magnesium Diasporal 300 and analogues are designed to address health problems caused by a lack of this substance. The prices of medicines, their composition and mechanism of action may differ, therefore, before using medicines, it is imperative to get the advice of a qualified doctor.

Video about Magnesium Diaspora

Diasporal magnesium for calf cramps: