Ganaton analogs are cheaper. List, price

Ganaton is a medication that activates gastrointestinal motility. In the list of its analogues, there are fairly cheap drugs that have the same therapeutic effect as the original. The use of the drug should be carried out according to the instructions.

Characteristics of the drug

Ganaton (analogues may be cheaper in composition from the original) is a drug that restores bowel function. The drug comes on sale in the form of tablets. The active ingredient is itoprid (hydrochloride, no more than 50 mg).

Additional elements:

• wax;
• titanium dioxide;
• magnesium salt of stearic acid;
• silicic acid;
• lactose;
• vegetable starch.

Each tablet is enteric coated. They have a chamfer and risk. The drug has a stimulating effect on the intestines and stomach. The active ingredient is able to suppress acetylcholinesterase and dopamine. The drug has a mild antiemetic effect.

The formulation is completely soluble in the intestine. Bioavailability is relatively high - over 80%. Its performance is not affected in any way by the presence of food in the muscular organ. The maximum concentration in the blood is reached after 35-40 minutes. after the first dose.

It binds to blood proteins by 93-95%. The active ingredient enters the systemic circulation and is distributed through the soft tissues of the stomach, liver, adrenal glands, kidneys and small intestine. Itopride is able to cross the blood-brain barrier.

The instructions for use prescribe the following indications:

• uncontrolled vomiting;
• heartburn;
• bouts of nausea;
• anorexia;
• abdominal cramps;
• flatulence.

Like most medicines, Ganaton has a number of absolute contraindications for use.

The drug is not prescribed:

• children under 16;
• pregnant and breastfeeding women;
• people with a history of intestinal, stomach bleeding.

Intolerance to itopride can be considered an absolute contraindication to use.

Basic instructions

According to reviews, the medication is well tolerated, side effects are rare.

The instructions for use prescribe the following ailments:

• itching;
• redness;
• rash;
• fulminant jaundice;
• increased salivation;
• constipation;
• the formation of fecal congestion;
• diarrhea;
• bouts of nausea;
• tremor;
• migraine;
• slight dizziness;
• gynecomastia;
• anaphylactic shock.

Ganaton is taken internally as a whole, without chewing or dissolving in water. The daily norm is no more than 150 mg, which is equivalent to 3 tablets. Elderly people and adolescent children (16-18 years old) may need to adjust the dosage regimen in the direction of decreasing it

Analogs

Ganaton (analogues are cheaper, no less effective) is a drug that eliminates excess gas formation.

In the pharmacy, you can buy medicines that have a therapeutic effect similar to the original:

• Motilak;
• Zofran;
• Motilium;
• Itomed;
• Metoclopramide;
• Cerucal;
• Domperidone;
• Itopra.

The above drugs can be bought at the pharmacy without a doctor's prescription.

Motilak

The structural analogue, like the original drug, is marketed in the form of enteric-coated tablets. The composition of medicines varies: Motilac contains domperidone, which acts as an active ingredient.

Additional elements include:

• titanium dioxide;
• silicon dioxide;
• vegetable starch;
• carboxymethyl cellulose;
• flavor identical to natural (mint).

Like Ganaton, Motilak is capable of stimulating the stomach and duodenum. Even with prolonged use, the drug does not cause extrapyramidal disturbances. Motilak, like Ganaton, has a mild antiemetic effect.

In comparison with the original, Motilak has a low bioavailability (no more than 20%). It binds to blood proteins by 90-92%.

Indications for use of the original drug and its generic are slightly different. Motilak is prescribed for:

• abdominal cramps;
• flatulence;
• heartburn;
• belching (bitter, sour);
• reflux esophagitis.

Unlike the original medication, the analog can be taken by children, pregnant and breastfeeding women.

The absolute contraindications to the use of Motilak include:

• perforation of the stomach;
• intestinal obstruction;
• a history of bleeding.

The drug is not recommended for patients suffering from hypersensitivity. The list of side effects of Motilak and Ganaton is about the same.

If the individually selected dosage regimen is not followed, the risk of developing:

• allergic reactions (rash, itching, urticaria);
• anaphylactic shock;
• gynecomastia;
• dyspeptic disorders (constipation, diarrhea, fecal congestion, vomiting, nausea).

Motilak and Ganaton tablets are taken orally. The daily dose is not more than 30 mg (3 tablets).

Zofran

Ganaton (cheaper analogs have a similar therapeutic effect with the original medication) is a drug belonging to the category of peristalsis stimulants.

Zofran has several forms of release:

• suppositories;
• syrup;
• pills;
• solution for intravenous and intramuscular administration.

The composition of the generic and the original drug is different. The first medication contains ondansetron (2, 4, 8, 16 mg). Zofran does not have a stimulating effect on the intestines and stomach. The drug also has an antiemetic effect. The mechanism of action of the analogue and the original medication is different. Generic is able to increase the level of serotonin in the body and stimulate the vagal afferent axons, stopping the development of the gag reflex.

Zofran and Ganaton are highly bioavailable. The active components of both drugs quickly penetrate the systemic circulation and are evenly distributed over the soft tissues of the internal organs. The list of indications for the use of Zofran is less extensive. Most often, it is prescribed during the rehabilitation period after surgery in order to relieve nausea and vomiting. Also, the drug in the form of suppositories, syrup and tablets can be used by patients after chemotherapy or radiation therapy.

Zofran and Ganaton have the same contraindications.

Medicines are not prescribed:

• children;
• breastfeeding and pregnant women;
• people suffering from hypersensitivity.

Zofran has a more extensive list of side effects in comparison with Ganaton.

If the dosage regimen is not followed, you may experience:

• hypokalemia;
• hypercalcemia;
• arrhythmia;
• bradycardia;
• depression;
• dizziness;
• headache;
• convulsions;
• anaphylaxis;
• laryngospasm;
• angioedema;
• diarrhea;
• constipation;
• hiccups;
• short-term loss of visual acuity.

Instructions for use differ depending on the formulation:

• solution - no more than 8 mg once intramuscularly or intravenously;
• tablets - no more than 8 mg once, 2 times a day;
• syrup - no more than 16 mg per day;
• suppositories - 2 suppositories per day.

Unlike the original drug, an independent excess of the therapeutic dose of Zofran can lead to the development of characteristic symptoms of an overdose. In this case, the patient is prescribed symptomatic treatment.

Motilium

Motilium can be categorized as Ganaton's generics. In addition to tablets, the drug is marketed in the form of a suspension. The active ingredient is domperidone. Auxiliary elements may vary depending on the formulation.

Motilium, like Ganaton, has a stimulating effect on the intestines and stomach. Both medicines have a mild antiemetic effect. The mechanism of action of the original and the analog is approximately the same - the active ingredients are capable of inhibiting dopamines. Unlike Ganaton, Motilium also helps cleanse the gastric walls. The bioavailability of the analogue is low - no more than 18-20%. The rate of absorption is not affected by the presence of food in the stomach.

Unlike Ganaton, Motilium is prescribed for:

• regurgitation syndrome;
• esophageal reflux;
• ulcerative lesions of the duodenum and stomach;
• flatulence;
• cholangitis;
• dyskinesia;
• peptic intestinal ulcers;
• reflux esophagitis;
• cholecystitis;
• hypotension;
• atony;
• nausea and vomiting.

The list of contraindications for both drugs is also different.

You can not take Motilium when:

• violations of the functional activity of the liver (including liver failure);
• perforation of the ulcer;
• bleeding of the intestines and stomach.

Diseases of the kidneys and the cardiovascular system (including acute failure) can be considered as relative contraindications for use.

Unlike Ganaton, Motilium is better tolerated by patients. In extremely rare cases, rash, urticaria, amenorrhea and galactorrhea may occur.

Daily rate:

• tablets - no more than 30 mg (3 tablets);
• syrup - up to 15 ml 2-3 times a day.

In case of an overdose of Motilium, patients complain of disorientation and severe drowsiness. There is no specific antidote, patients are prescribed symptomatic treatment

Itomed

Itomed is a structural analogue of Ganaton. Medicines have the same composition. The active ingredient is itopride hydrochloride (no more than 50 mg). The analogue goes on sale in the form of tablets. He, like Ganaton, has a stimulating and antiemetic effect.

The synthetic prokinetic has a beneficial effect on the motility of the gastrointestinal tract, restoring the rate of natural peristalsis. The mechanism of action is based on the ability of itopride to block acetylcholinesterase.

The original and the generic have approximately the same bioavailability. Both drugs are rapidly absorbed from the intestines. The active ingredient is determined in the adrenal glands, liver, kidneys, stomach and intestines after 35-45 minutes. after the first dose.

Indications for use:

• anorexia;
• heartburn;
• flatulence;
• vomit;
• nausea;
• cramping;
• pain in the epigastric region;
• gastritis, characterized by various dyspeptic disorders.

The analogue has a more extensive list of contraindications.

He is not appointed:

• children under 16;
• breastfeeding, pregnant women;
• people with a history of gastrointestinal bleeding;
• people suffering from mechanical perforation of the digestive tract.

It is forbidden to take Itomed in case of violation of the processes of absorption of galactose and glucose. Patients suffering from impaired functional activity of the kidneys and liver may need to adjust the dosage regimen. Instructions for the use of Ganaton and Itomed are the same: patients should take no more than 3 tablets per day.

The drug form is drunk whole, without chewing or dissolving in water.

If the dosage regimen is not followed, the following side effects occur:

• constipation;
• diarrhea;
• fulminant jaundice;
• nausea;
• increased salivation;
• gynecomastia;
• thrombocytopenia;
• leukopenia;
• tremor;
• insomnia;
• hives;
• anaphylactic shock.

When the therapeutic dose is exceeded by 3 or more times, characteristic symptoms of an overdose occur (dizziness, fainting, tremor, nausea, spasm in the abdominal cavity).

Metoclopramide

Ganaton, like Metoclopramide (a cheaper analogue), has high bioavailability. Generic is marketed in the form of a solution for intravenous, intramuscular administration and tablets. As with the original drug, Metoclopramide has a stimulating and antiemetic effect. The mechanism of action of the original medication and its analog is the same: itopride and metoclopramide hydrochloride block serotonin and dopamine receptors.

The active substances initiate the process of faster transport of food from the stomach to the small intestine. With the systematic use of both medicines, the pressure of the food sphincter increases, which minimizes the risk of gastric contents back up into the esophagus. Acid clearance is increased by accelerating natural peristalsis.

Ganaton and Metoclopramide tablets are rapidly absorbed in the intestines. Indications for the use of drugs vary. Metoclopramide is prescribed to accelerate peristalsis before radiography and probing.

The instructions for use of the analogue contain the following indications:

• ulcerative lesions of the digestive tract;
• dyskinesia;
• stenosis;
• atony and hypotension of the stomach, intestines;
• reflux esophagitis;
• flatulence.

The list of contraindications for a generic drug is more extensive.

It is strictly forbidden to take the drug to people suffering from:

• Parkinson's disease;
• bronchial asthma;
• pheochromocytoma;
• epilepsy;
• glaucoma;
• perforation of the gastric and intestinal walls;
• intestinal obstruction;
• mental disorders.

Also, it is not recommended to take the drug:

• elderly patients suffering from hypertension, hepatic, renal insufficiency;
• children under 18 years of age.

If the therapeutic dose is exceeded or if the dosage regimen is not adhered to against the background of prolonged use of metoclopramide, the following side effects may occur:

• drowsiness;
• vibration in the ears;
• depression;
• dyskinesis;
• protrusion of the tongue;
• parkinsonism;
• fatigue;
• anxiety;
• porphyria;
• leukopenia;
• diarrhea;
• constipation;
• dry mouth;
• galactorrhea;
• amenorrhea;
• gynecomastia.

Instructions for the use of Metoclopramide and Ganaton tablets are the same. Therapeutic dose is not more than 30 mg, which is equivalent to 3 tablets. The course of application is selected individually. The solution can be administered up to 3 times a day, 10-15 mg once.

Cerucal

In addition to tablets, Cerucal also goes on sale in the form of a solution. The composition of the original and the generic is different. Cerucal contains metoclopramide hydrochloride (in the form of monohydrate, 5-10 mg). The analogue of Ganaton is also able to block dopamine and serotonin receptors. The component fights heartburn and hiccups. Under its influence, the process of gastric emptying is accelerated.

The bioavailability of both medicines is relatively high. The original and its counterpart have the same indications for use.

Cerucal is prescribed for the following pathologies and clinical syndromes:

• flatulence;
• duodenal and stomach ulcers;
• dyskinesia;
• reflux esophagitis;
• atony, hypotension of the intestine;
• vomit;
• hiccups.
• Contraindications to the use of Cerucal:
• hepatic, renal failure;
• bronchial asthma;
• arterial hypertension;
• Parkinson's disease;
• the growth of prolactin-dependent neoplasms;
• extrapyramidal disorders;
• epilepsy;
• stenosis of the stomach;
• intestinal obstruction;
• perforation of the gastrointestinal tract;
• pheochromocytoma.

Like Ganaton, Cerucal is strictly forbidden to be taken by people suffering from hypersensitivity. The daily dose of the original and the generic is the same - you can drink no more than 3 tablets per day. The solution is intended for intravenous or intramuscular administration. This formulation is not prescribed for children under 14 years of age. The daily norm of the solution is no more than 15 mg, which is equivalent to 3 ampoules.

The side effects of the drugs are the same:

• drowsiness:
• dizziness;
• constipation;
• diarrhea;
• gynecomastia.

In most cases, the malaise goes away on its own after 2-3 days.

Domperidone

The original medicine and its generic have the same formulation. Medicines are sold in pill form. Their composition varies: Domperidone contains a component of the same name, which acts as an active agent. The analog stops vomiting, nausea and hiccups due to the ability of domperidone to accelerate the motor activity of the intestines and stomach.

The instructions for the use of Domperidone prescribe the following indications:

• belching;
• heartburn;
• bloating;
• flatulence;
• hiccups;
• intestinal atony;
• diseases accompanied by bouts of nausea and profuse vomiting;
• the period of preparation for radiation therapy.

Medicines have the same contraindications.

Domperidone, like Ganaton, is not prescribed for hypersensitivity:

• a history of intestinal and gastric bleeding;
• perforation of the stomach and intestines;
• intestinal obstruction.

Also, children's age, the period of bearing a child and breastfeeding are considered an absolute contraindication. The original and the analogue have approximately the same instructions for use: no more than 3 tablets per day.

The instructions for the drugs indicate the same side effects:

• gynecomastia;
• galactorrhea;
• hives;
• itching;
• rashes;
• cramping;
• dyspeptic disorders.

The course of administration of Domperidone is selected individually, depending on the age and condition of the patient.

Itopra

Ganaton (cheaper analogues do not require prescription dispensing) is an antiemetic agent. Itopra, like the original drug, is taken strictly according to the instructions. The analogue and the original drug have a dosage form of tablets. The active ingredient is itopride hydrochloride (no more than 50 mg).

The auxiliary elements are also the same:

• magnesium salt of stearic acid;
• hypromellose;
• vegetable starch;
• lactose;
• titanium dioxide;
• povidone.

Tablets of Itoprid and Ganaton are enteric coated. There is a chamfer and a risk. Medicines have a beneficial effect on the organs of the digestive tract, enhancing their motor skills. With the participation of the active component, the release and activation of acetylcholine occurs. The antiemetic effect is achieved due to the blockade of dopamine with itopride.

The active ingredient is absorbed quickly. It binds to blood proteins by 93-95%. Both drugs are metabolized by the liver. Inactive metabolites are excreted in the urine.

Isopra and Ganaton have the same indications for use:

• nausea;
• heartburn;
• anorexia;
• gastralgia;
• flatulence;
• chronic gastritis.

Both medicines are strictly forbidden to take:

• children under 16;
• pregnant and breastfeeding women;
• people suffering from galactose, glucose and lactose intolerance;
• people with a history of intestinal and stomach bleeding.

An absolute contraindication can be considered an individual intolerance to itopride.

Drugs, if the individually selected dosage regimen is not followed, can provoke the following side effects:

• irritability;
• dizziness;
• headache;
• gynecomastia;
• anaphylactic shock;
• rash;
• itching;
• hyperemia;
• thrombocytopenia;
• leukopenia;
• profuse salivation;
• constipation;
• diarrhea;
• nausea;
• lightning-fast jaundice.

Isopra and Ganaton tablets must be taken 2-3 times a day. The therapeutic norm is no more than 150 mg, which is equivalent to 3 tablets.

Price of funds

The cost of the drugs listed above may vary depending on the method of sale:

Name	Price
Ganaton	RUB 480-620
Motilak	440-530 rub.
Zofran	400-550 rub.
Motilium	RUB 380-430
Itomed	400-480 rub.
Metoclopramide	420-490 rub.
Cerucal	RUB 450-520
Domperidone	RUB 350-480

Experts recommend purchasing medicines only from pharmacies. When placing orders in online stores, there is a high risk of running into a fake. Medicines are dispensed without a prescription.

Ganaton is a fairly effective drug with a number of structural, cheaper analogues. If there are contraindications to the use of the original medicine, the patient should consult a doctor. The specialist will select the safest and most effective substitute medication.

Video about the analogue of the drug Ganaton

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