Etoricoxib 30-60-90-120 mg. Price, instructions for use, reviews

Etoricoxib is a Hungarian drug has anti-inflammatory and antipyretic effect. The medication is produced in tablet form, while the dosage of the active element can be 30, 60, 90, as well as 120 mg. A different percentage of the main component in the drug facilitates the dosing process for the patient and affects the price of the medication.

Composition and form of release

Etoricoxib tablets have a round and biconvex shape, with a white core and a smooth film coating. The color of the coating depends on the dosage of the active element: for 30 mg, the color of the coating is blue; for 60 mg the color is dark green; for 90 mg the color is white; and for 120 mg the color is light green. On one side of the tablet there is a number corresponding to the dosage of the main component.

The product is packed in foil blisters in the amount of 2.7 and 14 pcs. The package, along with the instruction, may contain 1 blister (which contains 2, 7 or 14 tablets), 2, 4 or 7 blisters, including 14 tablets.

The following substances are included in the composition of the tablets:

List of components	Component characteristics
The main component
Etoricoxib	The substance has a pronounced anti-inflammatory and analgesic effect.
Minor components of the tablet core
Anhydrous Calcium Hydrogen Phosphate	The element is involved in the formation, strengthening and growth of bone tissue, as well as in the transmission of nerve impulses. Another component normalizes blood coagulation, improves the functioning of the cardiovascular system and the musculoskeletal system.
Microcrystalline cellulose types 101 and 102	The substance is a preservative and filler, and also facilitates the dissolution of the tablet and improves the absorption of the constituents used. In this case, types 101 and 102 differ only in the size of the MCC particles.
Povidone K 25	The component binds and removes harmful substances from the body, which are actively formed during the development of inflammatory processes.
Crospovidone type A	The ingredient allows the tablet to dissolve faster in the digestive tract.
Magnesium stearate	The element gives the tablets a homogeneous texture, and also facilitates the process of their dissolution.
Shell elements
Aquapolish P (green, white, blue)	The component facilitates the sliding of the tablet along the digestive tract, and also gives the shell the desired color.

For all dosages, the same components are used, but in different proportions (both the active element and the auxiliary), the dyes used also change.

Pharmacological properties

Etoricoxib 30-120 mg, the price of which depends on the concentration of the active substance, belongs to the group of anti-inflammatory drugs with a non-steroidal composition. Also, the drug has antipyretic properties.

Pharmacodynamics and pharmacokinetics

Etoricoxib tablets (regardless of the concentration of the main element) have the following effect on the body:

• inhibit the activity of substances that are responsible for the development of inflammation;
• reduce the severity of signs of already developing inflammation;
• do not have a negative effect on the mucous membranes of the digestive tract and do not disrupt platelet activity;
• reduce vascular permeability, as a result, the likelihood of developing inflammation and an allergic reaction decreases;
• activate blood microcirculation;
• block energy supply at the site of the inflammatory process;
• regulate the activity of the kidneys and the nervous system;
• participate in the formation, as well as growth and strengthening of bones;
• improve the work of the musculoskeletal system, as well as the heart and blood vessels;
• remove harmful elements from the body;
• lowers body temperature by lowering the excitation of brain cells responsible for thermoregulation.

After taking the pill on an empty stomach, the pain relieving effect occurs within the first hour. If the drug is taken after a meal, then its effect occurs within the first 3 hours. At the same time, food does not reduce the anesthetic and anti-inflammatory effect.

When using Etoricoxib, it should be borne in mind that the main component binds to blood proteins, therefore it penetrates into all organs and tissues, including the fetus through the placenta. The decomposition of the main substance occurs in the liver and is excreted from the body with feces within 22 hours. The higher the amount of the active ingredient in the tablet, the more pronounced the analgesic effect.

Indications for use

Etoricoxib 30-120 mg, the price of which depends on the manufacturer's company, can be prescribed by a doctor in the following cases:

• rheumatoid arthritis. The disease is chronic. The inflammatory process affects the connective tissue, joints and internal organs. Etoricoxib reduces the severity of symptoms;
• osteoarthritis. The disease is manifested by a violation of the condition of the cartilage tissues of the joints and is accompanied by severe pain;
• ankylyzing spondylitis. Pathology mainly affects the joints of the spine. The tablets reduce the pain symptom;
• gouty arthritis. The cause of the development of the disease is the pathological deposition of salts in the articular tissues and is accompanied by severe pain;
• elimination of the process of inflammation, swelling and pain in the joints, which are provoked by trauma. The tablets are used only after being prescribed by a doctor;
• elimination of toothache during dental procedures.

Important. Etoricoxib only eliminates the symptoms of the listed pathologies, but does not fight the basis of the development of the disease.

Contraindications

Etoricoxib tablets (regardless of the amount of the main element in the composition) should not be taken in the following cases:

• allergy to the composition of the medication;
• bronchial asthma in any form;
• inflammation and proliferation of tissues (formation of polyps) in the mucous membranes of the nasal cavity;
• the patient has an aspirin intolerance;
• exacerbation of ulcers in the stomach or duodenum;
• inflammation of the intestinal mucosa;
• the presence of bleeding in the gastrointestinal tract or in the brain;
• poor blood clotting;
• severe heart failure;
• impaired oxygen delivery to the heart muscle;
• the presence of liver pathologies in severe form;
• exacerbation of renal failure;
• high potassium content in the body;
• violation of the state and patency of blood vessels;
• the period of bearing a child or when planning conception;
• age up to 16 years. Since the safety of the drug for this age has not been studied;
• high blood pressure (more than 140 to 90 mm Hg. Art.);
• recent heart surgery.

If a woman is breastfeeding a baby, then for the period of treatment it is required to transfer the baby to a mixture.

Patients with the following pathologies should take pills under the special supervision of a physician:

• a tendency to disrupt the work of the digestive tract;
• heart failure;
• an increased amount of fats and complex lipid-containing proteins;
• diabetes;
• increased pressure value (not higher than 140 to 90 mm Hg. Art.);
• the patient smokes a lot (more than half a pack per day);
• severe edema and fluid retention in the body;
• pathology of the kidneys and liver in mild and moderate severity;
• dehydration of the body.

Important. Patients over 65 years of age should take Etoricoxib at the lowest dosage and with extreme caution.

Method of administration and dosage

Etoricoxib 30-120 mg, the price of the drug is not budgetary, should be taken orally and preferably before eating (then the therapeutic effect will come faster). At the same time, doctors recommend using tablets with a minimum dosage for treatment, and the course should be as short as possible.

Features of therapy with Etoricoxib for various pathologies:

List of diseases	Single dose	Frequency rate and peculiarity of reception at 24 hours
Osteoarthritis	30 mg. If necessary (if the pain is poorly reduced), it is allowed to increase the dosage to 60 mg.	One-time. The maximum daily dose should not exceed 60 mg.
Rheumatoid arthritis	60 mg. If the pain is severe, the doctor may increase the dose to 90 mg.	One-time. The permissible daily dose is not more than 90 mg.
Gouty arthritis	90 mg. If the pathology is in the acute stage, then the dose can be increased to 120 mg. In this case, the course should not exceed 8 days.	One-time. The maximum daily dose is not more than 120 mg.
Ankylyzing spondylitis	60 mg. If pain persists, the specialist may increase the dosage to 90 mg.	One-time. The permissible daily dose is not more than 90 mg.
Acute tissue inflammation	Etoricoxib should only be used for severe pain. The initial dosage should not exceed 30 mg. Further, it is allowed to increase the dose (carried out by a doctor) up to 60 mg.	One-time. The maximum allowable dose should not exceed 60 mg. And also, it is advisable not to extend the course for more than 5 days.
Dental procedures	90 mg before the procedure (no more than a day) and 90 mg for 3 days after the procedure. It is forbidden to use tablets for longer.	One-time. The duration of use of the tablets is no more than 4 days and no more than 90 mg per day.

The dosage of Etorikoxib should be agreed with the doctor, since the specialist takes into account the presence of chronic diseases and the severity of the pathology.

The features of the use of tablets for patients from a special group are discussed below:

• elderly patients. Regardless of the purpose of administration, the initial single dose should not exceed 30 mg. If side effects do not appear and the pain symptom is poorly reduced, then the doctor (only a doctor) can increase the dosage;
• patients with liver pathologies. Without considering the reason for using the medication, the initial dose should be 30 mg. If the disease is mild, then the treating specialist can increase the dosage to 60 mg;
• patients with kidney disease. The starting dosage is 30 mg. In the absence of side effects, the doctor may increase the dose to 60 mg.

Children under 16 years of age, with pain of any severity, are not prescribed Etoricoxib.

Side effects

Taking Etoricoxib tablets (even in a small dosage) can provoke the development of the following adverse reactions:

• dizziness, as the drug affects the blood supply to the brain;
• feeling of heartbeat;
• severe weakness;
• headache with varying degrees of manifestation;
• increased blood pressure;
• development or exacerbation of heart, renal or hepatic failure;
• liquefaction of stools and an increase in the number of acts of defecation;
• constipation;
• unproductive cough;
• nausea, as a result, a deterioration in appetite is allowed;
• hiccups;
• vomit;
• increased appetite, as a result of weight gain;
• the appearance of pain and heaviness in the stomach;
• disruption of the digestive tract organs or the development of inflammatory processes in them;
• increased gas formation in the intestines, manifested by pain and bloating;
• increased production of liver enzymes;
• swelling of tissues;
• joint aches, chills and other signs of the development of influenza;
• changes in taste and smell;
• severe drowsiness or lack of sleep;
• burning or tingling sensation on the skin;
• increased sensitivity of the teeth;
• violation of cerebral circulation;
• the development of depression;
• unreasonable anxiety;
• decreased concentration of attention;
• flushing of the face;
• a decrease in the number of leukocytes, platelets and hemoglobin in the blood;
• decreased vision;
• noise or ringing in your ears;
• feeling of rotation of the body or surrounding objects;
• development of conjunctivitis;
• shortness of breath or bronchospasm;
• bleeding from the nose or in the digestive tract;
• the development of infectious diseases in the upper respiratory and urinary tract;
• dry mouth;
• muscle pain;
• muscle cramps or spasms;
• the appearance of protein in the urine;
• violation or increase in the number of heart contractions;
• an increase in the amount of salts in the urine;
• hallucinations or confusion.

  

If the patient is allergic to the composition, then the patient more often noted the development of suffocation, the appearance of a rash, a runny nose.

Overdose

Etoricoxib (the price of the product can be obtained from your doctor) should be taken in a strictly prescribed dosage. If you exceed the prescribed amount (for example, take more than 700 mg per day), the development of serious poisoning is not excluded, which can be recognized by the following signs:

• severe migraine, it is impossible to even turn your head;
• severe pain in the region of the heart;
• complete lack of strength;
• severe abdominal pain;
• a sharp increase in blood pressure to high levels;
• swelling of the limbs, face and internal organs as a result of impaired renal function;
• yellowing of the skin due to deterioration of the liver;
• vomiting accompanied by diarrhea. In this case, blood may be present in the vomit and in the feces;
• refusal to eat;
• severe aches in muscles and joints;
• loss of balance;
• temporary loss of memory, vision, or hearing;
• development of suffocation;
• falling out of reality or complete detachment from the real world;
• with allergies, the development of Quincke's edema is noted.

If no more than 40 minutes have passed after the poisoning, then the victim will be effectively washed with the intake of sorbents. If more time has passed, then you need to call for urgent help (since you need to clean the blood with an artificial kidney), and use symptomatic therapy before the doctors arrive.

special instructions

Before starting the use of Etoricoxib (in order to reduce the likelihood of developing an adverse reaction), the following subtleties of using the medication should be studied:

• observe the individual dosage if the patient has pathologies from the list of restrictions;
• use the drug in combination therapy only with the permission of the doctor, since its interaction with other drugs must be taken into account;
• pills cannot be combined with alcohol, as it increases the load on the heart, and also increases the toxicity of the medication;
• start using tablets with a minimum dosage;
• if the use of pills caused the appearance of a negative reaction in a severe form, then the treatment should be stopped immediately;
• the drug can cause disruption of the kidneys, heart and gastrointestinal tract, as well as provoke a sharp increase in pressure;
• the first 2 weeks of the course (if the treatment is long), you need to check the work of all vital organs and the composition of the blood.

It is forbidden to drive a car or do dangerous work while taking Etorikoxib.

Drug interactions

Etoricoxib (30-120) mg (the price of tablets is the lowest in online pharmacies) is used in complex therapy only with the permission of a doctor.

The following is a brief overview of medications with which it is not recommended to combine the drug:

• aspirin increases the likelihood of developing internal and nosebleeds, as well as exacerbation of ulcers and erosions in the digestive tract;
• oral contraceptives increase the risk of a blood clot in your blood vessels;
• Warfarin (a blood thinner) increases the duration of blood clotting;
• other non-steroidal anti-inflammatory drugs increase the burden on the kidneys and increase the likelihood of high blood pressure;
• immunosuppressants increase the burden on the kidneys;
• Etoricoxib retains lithium in the body when taking lithium-containing medicines;
• diuretics reduce the effectiveness of the tablets and increase the burden on the kidneys.

Do not use Etoricoxib with liquid medicines containing ethanol, as the toxic effect of both drugs increases.

Analogs

Etoricoxib tablets are distinguished by a large list of adverse reactions and a high price, so the doctor can replace the medication with the following analogues:

List of substitutes, subtleties of sale and price	Active element and action of the medication	Features of the admission rules
Arcoxia. Prescription remedy. The price for 28 tablets with a dosage of 90 mg is 1,300 rubles.	The analogue contains an identical active element and in similar proportions. The medication has a pronounced anti-inflammatory and analgesic effect.	The substitute practically does not differ from the original in terms of indications, age and other restrictions and also has a large list of adverse reactions.
Denebol. Sold by prescription. The average price is 600 rubles for 10 tablets.	The main component (rofecoxib) in tablets is contained in a concentration of 25 and 50 mg. The drug has analgesic, antipyretic, anti-inflammatory and anti-edema properties.	The analogue has a wider list of indications. Also, the remedy is distinguished by a different and smaller list of contraindications and side effects. Age limit - the drug is not used until 12 years of age.
Ranselex. Prescription analog. The cost is about 200 rubles.	The active ingredient (celecoxib) is contained in an amount of 100 and 200 mg per capsule. The substitute has a pronounced anti-inflammatory effect.	The list of indications for the use of the analog is close to the original, and the lists of side effects and prohibitions are much smaller.
Celebrex. Prescription substitute. The price for 10 capsules with a concentration of 200 mg is about 420 rubles.	The main component (celecoxib) is included in the capsule in the amount of 100 and 200 mg. The substitute has anti-inflammatory and analgesic effects.	The tool, like the original, has a large list of prohibitions and side reactions. Also, the medication is similar to Etorikoxib in the list of indications.
Exineph. Prescription drug. The price is not specified, as the medication is temporarily out of stock.	The medication contains an identical active element in the amount of 60, 90 and 120 mg. The drug has anti-inflammatory and antirheumatic effects.	The list of appointments, prohibitions and side effects is identical to the original. But at the same time, the analogue is not used until the child reaches 18 years of age.

Only the attending physician can replace Etorikoxib. Since when choosing a remedy, one must take into account the reason for the search for an analogue, as well as the general well-being of the patient.

Terms of sale, storage and prices

Etoricoxib (30-120) mg (price listed below) can be purchased strictly upon presentation of a prescription. In this case, the prescribed dosage and course must be indicated in the prescription. At home, tablets should be put in a dark place with a temperature of 2 to 30 degrees. The shelf life of the medication is 36 months. Keep the tablets away from children.

The price of Etoricoxib tablets varies depending on the region, the concentration of the active element and the amount of the drug in the package. (the table shows prices for the most popular forms of release):

Number of tablets	Tablet dosage	Minimum price	Maximum price
7	90 mg	RUB 180	RUB 290
120 mg	RUB 250	RUB 380
14	60 mg	RUB 200	RUB 360
28	60 mg	RUB 350	RUB 490
90 mg	RUB 540	RUB 690

Etoricoxib relieves pain quickly and for a long time, even with a single dose. But when using it, it should be borne in mind that the medication is "rich" in a list of side effects, which often appear if the patient does not comply with the prescribed dosage (more often 30 mg is used). Additionally, patients note a fairly high price for the product.

Author: Kotlyachkova Svetlana