Miscellaneous

Is it possible to breastfeed monural or not?

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Content

  1. Release form
  2. Chemical composition
  3. Pharmacological properties
  4. Pharmacodynamics and pharmacokinetics
  5. Indications for use
  6. Contraindications
  7. Can the drug be used while breastfeeding?
  8. Effects on breast milk and baby
  9. Dangers of use with hot water
  10. Instructions for use for breastfeeding, dosage
  11. Side effects
  12. Overdose
  13. special instructions
  14. Drug interactions
  15. Analogs
  16. Terms, conditions of sale and storage
  17. Price
  18. Video about the drug Monural

For the treatment of bacterial cystitis, nonspecific urethritis and postoperative urinary tract infections, it is used in traditional medicine antibacterial drug Monural.

The drug has pronounced bactericidal properties, as it helps to destroy bacteria and viruses. The drug can be taken by adults and children over 5 years old. During pregnancy and breastfeeding, Monural will have to be abandoned. Otherwise, there is a risk of complications that can negatively affect the health of the child.

Release form

The drug Monural is produced in the form of small white granules, which are intended for the preparation of a medicinal solution. The medicine has a delicate fruit aroma. The product is realized in a four-layer laminated sachet-bag, which contains 3 g of granules. 1 carton pack contains 1-2 sachets.

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Chemical composition

It is strictly forbidden to take Monural while breastfeeding without prior consultation with a therapist. Otherwise, the baby may develop an allergy to the components of the drug. Fosfomycin trometamol is included in the composition of the drug as an active substance.

The auxiliary components help to enhance the therapeutic effect of the drug:

  • Saccharin.
  • Flavors (tangerine and orange).
  • Sucrose.Is it possible to breastfeed monural or not?

The components of the drug suppress the initial stage of the formation of the bacterial cell wall. Monural is characterized by high activity against many gram-positive microorganisms. The drug is an analogue of phosphoenol pyruvate, which is widespread in pharmacology.

Pharmacological properties

Monural has a bactericidal principle of action, helps prevent the development of pathogenic microorganisms. The drug is effective against bacteria of gram-positive and gram-negative types. Correctly compiled by a specialist, a course of therapy helps to overcome diseases that are provoked staphylococci, proteas, streptococci, Klebsiella, enterobacteria or other types of pathogenic microorganisms.

An active component of a bactericidal agent in combination with cephalosporins, penicillins, aminoglycosides, carbapenems, fluoroquinols and glycopeptides exhibits a pronounced synergistic effect, which is extremely important in the severe course of diseases that were provoked by multidrug-resistant pathogens.

For example, enterococci, staphylococci, enterobacteria. But only a doctor should make a decision on the advisability of carrying out combined drug therapy, since in Otherwise, there is a high probability of developing bronchospasm, vulvovaginitis, antibiotic-associated colitis.

In modern pharmacology, Monural is one of the most effective drugs for cystitis. In this case, the main part of the drug is excreted from the body along with urine, due to which the likelihood of developing dysbiosis is practically excluded.

Monural is also effective for pyelonephritis, when it is necessary to eliminate pathogens not only in the bladder, but also in the urinary tract. But to achieve the desired therapeutic effect, it is necessary to undergo a full course of combined drug treatment.

Pharmacodynamics and pharmacokinetics

Monural contains a natural antimicrobial substance (fosfomycin trometamol), which helps achieve a powerful bactericidal effect by suppressing the formation of the bacterial cell wall. Due to the inhibition of the early stage of peptidoglycan synthesis, the process of creating the cell wall is disrupted.

The active ingredient of the drug prevents bacteria from adhering to the bladder mucosa. It is adhesion in 98% of cases that is the key factor due to which recurrent urinary tract infections develop. But at the same time, fosfomycin trometamol easily penetrates into breast milk and can accumulate in the child's body, which is why the drug is contraindicated for breastfeeding.

In the body, the drug breaks down into trometamol and fosfomycin. Moreover, the first substance does not have an antibacterial effect. With a single use, the bioavailability indicator of Monural is in the range from 30 to 66%. The maximum concentration of the drug in blood plasma (23 μg / ml) is achieved after 3-4 hours. after oral ingestion of granules.

The active component of the drug is not metabolized and does not bind to blood proteins. The main part of the drug is excreted in urine, and 20-28% of the dose taken is excreted unchanged along with feces.

Indications for use

Monural has a wide spectrum of action and high efficiency in the fight against acute and chronic diseases.

In the annotation to the drug, the manufacturer indicated the following indications for use:

  • Acute attacks of recurrent bacterial cystitis. This disease is characterized by the occurrence of acute attacks at least 3 times a year.Is it possible to breastfeed monural or not?
  • Infections of the urinary system of bacterial origin (postoperative period). It is a syndrome that includes clinically manifest infections of the upper and lower urinary tract.
  • Asymptomatic bacteriuria in women during the period of bearing a child. This is a pathological condition in which a rapid growth of bacteria occurs in urine (in a healthy person, urine is sterile), but there are no symptoms of infection.
  • Nonspecific bacterial urethritis. The disease develops in the body due to the ingress of microbes with atypical flora into the mucous membrane of the urethra.
  • Acute bacterial cystitis. This is an inflammation of the mucous membrane of the bladder due to the introduction and long-term stay in it of bacteria, less often viruses and fungi.
  • Prevention of bacterial infections of the urinary system during surgical interventions / diagnostic transurethral manipulations.

The drug is well tolerated, but before buying it, you need to go through a complex examination of the body so that the doctor can correctly diagnose and prescribe an individual scheme treatment.

Contraindications

It is not recommended to take Monural while breastfeeding, so as not to harm the baby. If it is impossible to cancel the drug, then during the treatment the woman should transfer the baby to artificial feeding.

Is it possible to breastfeed monural or not?

The following contraindications are indicated in the instructions for the medication:

  • Hypersensitivity of the body to the components of the drug.
  • Children's age (up to 5 years old).
  • Severe renal failure, in which the Clcr values ​​are below the 10 ml / min mark.

In laboratory conditions, the principle of the effect of the drug on the body of a woman and her unborn child has not been studied. For this reason, gynecologists do not recommend taking Monural during pregnancy in order to reduce the likelihood of complications.

Can the drug be used while breastfeeding?

The components of the drug Monural easily pass into breast milk, which can be dangerous for the baby. If the patient is shown antibiotic therapy, then it is necessary, together with the attending physician, to choose a more suitable an analogue of the drug that will be safe for the baby, or transfer the child to an artificial one during treatment feeding.

Effects on breast milk and baby

Taking Monural is incompatible with the process of breastfeeding a baby. The risk is associated with the fact that the work of the excretory system has not yet been normalized in children under 6 months of age, which is why the body cannot get rid of drugs at the required rate.

That is why you should refrain from using any medications during lactation. If a woman neglects this rule, then the child's health may deteriorate significantly against the background of the development of adverse reactions (for example, diarrhea, urticaria).

Dangers of use with hot water

The use of Monural during breastfeeding is dangerous due to the fact that it is active the active substance of the drug with a probability of 99% will negatively affect the work of the gastrointestinal tract of the baby. The medicine can disrupt the work and the normal composition of the intestinal microflora.Is it possible to breastfeed monural or not?

The baby's condition may also worsen with diarrhea, vomiting, and an allergic reaction. In such a situation, to normalize the child's condition, you need to consult a pediatrician, who, based on the collected history, will prescribe effective symptomatic treatment.

Instructions for use for breastfeeding, dosage

Monural during breastfeeding can be taken only subject to prior consultation with a urologist and in accordance with the prescribed treatment regimen. During the course of the therapeutic course, the child must be transferred to artificial feeding.

It is recommended to take the drug on an empty stomach (at least 2 h. before meals), immediately after emptying the bladder. For the treatment of cystitis, Monural should be taken at bedtime. Before use, the contents of 1 sachet-packet must be dissolved in 70 ml of water at room temperature. The duration of the therapeutic course is 1 day.Is it possible to breastfeed monural or not?

If the patient is diagnosed with a recurrent urinary tract infection, then after 24 hours. after the first use of Monural, you need to drink another 1 dose of the drug. In this case, it is possible not only to eliminate the painful symptoms of the disease, but also to stop the inflammatory process.

To prevent infection of the urinary tract during surgery or transurethral diagnostics, you must take the contents of 1 package of Monural for 3 hours. before the procedure, as well as one day after its completion. If the patient is diagnosed with renal failure, then the standard dosage should be reduced by 50%, increasing the interval between doses of the medication.

Only the attending physician can make changes to the treatment regimen, since self-medication is fraught with the development of complications and further progression of the disease. Breastfeeding of the child can be resumed only 3-4 days after the completion of drug treatment.

Side effects

Subject to the recommendations of the urologist, the drug Monural is well tolerated by the body of patients of different ages.

Only in rare cases do side reactions occur:

  • Attacks of nausea, vomiting.
  • Heartburn.
  • Diarrhea.
  • Hives, burning and itching of the skin.
  • General malaise.
  • Migraine.
  • Fever.
  • Chills.
  • Increased heart rate.
    Is it possible to breastfeed monural or not?
    Monural for breastfeeding
    Is it possible to breastfeed monural or not?

In the event of adverse reactions, repeated use of the drug is unacceptable. Otherwise, there is a risk of complications that can prevent the woman from continuing to breastfeed her baby. For example, there will be an inflammatory process in the intestines or paracystitis, which affects the fibrous tissue around the bladder and implies prolonged antibiotic therapy.

Overdose

Exact adherence to the instructions of the urologist excludes the likelihood of an overdose with Monural. But the manufacturer of the medication warns that if you take 2-3 sachets of the bactericidal medicine during the day, then with the probability 98% will experience the following symptoms:

  • Aching pain in the epigastric region.
  • Nausea, vomiting.
  • An increase in body temperature to 38 C.
  • Discomfort in the muscles.
  • Aching pain in the lower abdomen.
  • Limb tremor.
  • Headache attacks.
  • General malaise.
  • Increased concentration of urea in blood plasma.
  • Stool disorder.
  • Neuromuscular arousal.
  • Eosinophilia. This is a condition in which there is an increase in the level of eosinophils in the blood.
  • Pancytopenia. This is a pathological condition, implying a decrease in the composition of all elements of circulating blood (platelets, leukocytes, platelets and erythrocytes) that form its composition.
  • Anemia.
  • Thrombocytopenia.
  • Bronchospasm.
  • Drowsiness.
  • Increased irritability.
  • Increased heart rate.

If these symptoms occur, you should seek qualified medical help. In severe cases, forced diuresis may be required to normalize the patient's condition. Only on the basis of the collected history will the doctor be able to prescribe effective symptomatic treatment.

special instructions

It is advisable to use Monural during breastfeeding in cases where a woman is diagnosed with a recurrent course of urinary tract infection. After transferring the child to artificial feeding, the drug must be taken in combination with B-lactam antibiotics to exclude the possibility of further progression of the disease.Is it possible to breastfeed monural or not?

During the period of the therapeutic course, it is recommended to monitor the functioning of the liver and kidneys, as well as periodically conduct a biochemical blood test.

Laboratory studies have shown that Monural is effective in the treatment of uncomplicated urinary tract infections. In more severe cases, it is additionally necessary to take drugs that contain a b-lactam ring. The use of the drug during meals slows down the absorption of active and auxiliary components into the systemic circulation by 45-60%. For this reason, it is recommended to take Monural on an empty stomach or for 2 hours. before / after meals.

Patients with diabetes mellitus should remember that sucrose is part of the bactericidal agent. In rare cases, the drug provokes the development of antibiotic-associated colitis, which is why during the passage drug therapy in the event of severe diarrhea, you must immediately seek a qualified medical help.

The specialist will prescribe an individual treatment regimen, which cannot include drugs that inhibit intestinal motility.

Monural can cause dizziness, which is why, after using this medication, it is not it is recommended to drive a car and complex mechanisms that require increased concentration attention.

Drug interactions

The pharmacological agent Monural is not recommended to be taken simultaneously with antacids and potassium salts, as it will be essential the concentration of fosfomycin timolol in the patient's blood plasma is reduced, which will negatively affect the result of the medication therapy.

Is it possible to breastfeed monural or not?

In combination with penicillins, the active substance of the bactericidal drug exhibits pronounced synergism. actions, which is especially important in the fight against severe infections that were provoked by multidrug-resistant pathogens. The feasibility of combination therapy with breastfeeding should be assessed by a urologist and a gynecologist, so how important is the patient's age, her current condition and the fact of the presence (absence) of concomitant pathologies.

Analogs

If there are contraindications to the use of Monural, then it can be replaced with another medicine with a similar principle of action. You must first consult with a qualified urologist, since self-treatment of urinary tract infections can provoke the development of acute pyelonephritis, which is accompanied by high fever and general intoxication organism.

Name of the medicinal product Description
Hexamethylenetetramine The drug has dose-dependent disinfecting and disinfecting properties. Methenamine is the main component of Hexamethylenetetramine. It is recommended to use the drug for infectious diseases of the urogenital tract. For example, with inflammation of the bladder, renal pelvis, calyces. Contraindications: pregnancy, lactation, renal failure, children (up to 6 years). To achieve a positive therapeutic effect, the tablets should be taken in the morning and in the evening. A single dosage should not exceed 1 g. The solution for intravenous administration is prescribed in a dosage of 2-4 g. The doctor determines the duration of the therapeutic course individually. The cost of a pharmacological agent ranges from 46 to 260 rubles.
Nitroxoline The main active ingredient of the drug is nitroxoline. Auxiliary components: aerosil, yellow-orange dye, sucrose, beeswax, E171, talc, paraffin, magnesium carbonate. The drug is intended for the treatment of infectious and inflammatory diseases of the urinary tract (for example, cystitis, pyelonephritis, epididymitis, inflammation of the urethra). The pharmacological agent is also recommended to be taken to prevent the development of infectious complications during diagnostic and therapeutic procedures. For example, cystoscopy, catheterization. The drug should not be taken in the presence of the following diseases and conditions: cataracts, severe forms of liver disease, pregnancy, lactation, neuritis. You need to take Nitroxoline 2 tablets 4 times a day before meals. In a severe course of the disease, the dosage of the pharmacological agent can be doubled. A standard therapeutic course is designed for 2-3 weeks. A safe treatment regimen can only be drawn up by a urologist. Nitroxoline costs 320-390 rubles.Is it possible to breastfeed monural or not?
Zyvox It is an effective antibacterial agent. Linezolid is used as the main substance. The following components help to enhance the therapeutic effect of the drug: corn starch, microcrystalline cellulose, hyprolose, sodium carboxymethyl starch, E572. Zyvox is prescribed for the treatment of diseases of an infectious and inflammatory etiology caused by exposure to linezolid-sensitive gram-positive anaerobic and aerobic bacteria. The drug is prohibited to use during pregnancy, lactation, as well as children under 12 years of age. Zyvox should be taken 2 times a day, 1 tablet (600 mg). The recommended daily dosage of the drug is 1200 mg. The drug should be taken at intervals of 12 hours. Treatment should last 10 to 28 days. In pharmacies in Moscow, Zivoks costs 9217-18450 rubles.

Among the available analogues of Monural, one can also distinguish: Ristomycin sulfate, Sanguirithrin, Amizolid. Before buying any medicinal product, you should consult with a urologist and undergo the necessary medical examination in order to find out exactly the cause of your unwell.

Terms, conditions of sale and storage

The pharmacological agent Monural can only be purchased with a doctor's prescription. Granules can be used within 3 years from the date of release, which can be viewed on the package. It is necessary to store the pharmacological agent in a dry place, out of reach of direct sunlight. The optimum air temperature is + 13-27 C.

Price

The drug Monural has a wide spectrum of antimicrobial action. The drug is characterized by good tolerance and high rates of effectiveness in the treatment of urological infections.

In this case, the drug is contraindicated for breastfeeding, since the components of the drug can get into the child's body together with breast milk, due to which the baby may experience disturbances in the functioning of the gastrointestinal organs path. To prevent the development of complications, it is forbidden to self-medicate.

Video about the drug Monural

Monural for cystitis:

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