An analogue of Sofradex for the ear. Price

Sofradex is an Indian hormonal agent with antibacterial, antihistamine and anti-inflammatory activity. The drug is used to eliminate ear and eye diseases. Due to the inclusion in the composition of two antibiotics and a hormonal component, the drug is highly effective. In this regard, it is rather difficult to choose an analogue of a medication with identical characteristics.

Characteristics of the drug

Sofradex is presented in the form of a clear solution with a pronounced smell of alcohol.

The active components of the drug are (data are given per 1 ml of the drug):

• framycetin at a dose of 5 mg is an antibiotic;
• dexamethasone weighing 0.5 mg is a synthetic glucocorticosteroid with anti-inflammatory, antihistamine and immunosuppressive effects;
• gramicidin in the amount of 0.05 mg is an antibiotic.

The main substances have anti-inflammatory, antihistamine and antibacterial effects, which are used to eliminate ear and eye pathologies. The product is sold in 5 ml glass jars. A dropper dispenser is attached to dispense the solution.

Sofradex should not be used for tuberculosis, if the patient has a fungal or viral infection, in violation of the integrity of tissues and allergies to the components of the solution. In addition, due to the presence of a hormone in the drug, it is not used until the child is 7 years old, as well as during pregnancy and lactation.

Basic instructions

The analogue of Sofradex for the ear can be either hormonal or not. The original is not just a hormonal preparation, but also contains antibiotics, therefore, when applying it, it is necessary to take into account the following features:

• the solution may cause a burning sensation or irritation;
• the remedy (especially when used for a long time) can cause the development of superinfection (Sofradex contributes to a strong decrease in immunity);
• the medication is strictly forbidden to use if the integrity of the eardrum is damaged;
• the dropper dispenser must be rinsed after each procedure and stored dry;
• Sofradex cannot be combined with antibiotics, as the likelihood of deterioration of the kidneys or liver increases;
• due to the hormonal and antibacterial composition, the drug is prohibited to use for more than 1 week (in rare cases, longer therapy is allowed, but only under the supervision of a doctor).

The development of an overdose of a medication is unlikely even if it is swallowed, therefore the remedy is considered safe.

The storage time of the solution is reduced to 30 days after opening the bottle.

Analogs

Analogues of Sofradex may be required if the drug has caused an allergy, there is an age limit, or the product is simply not on sale. In this case, you can replace the original with the following analogs.

Garazon

The analogue of Sofradex for the ear is Garazon, these are Belgian drops, which, like the original, can be purchased after presenting a prescription.

Comparison table:

Basic data of medicines	Drug names
Sofradex	Garazon
Solution type	The tool is represented by a transparent liquid that has the smell of alcohol.	The solution is colorless, but a yellow tint may be present.
Vial volume	5 ml. Glass bottle, there is a dropper dispenser.	5 ml. The vial is made of plastic and has a dropper.
Main elements	Framycetin, gramicidin and dexamethasone.	Betamethasone and gentamicin.
Effects of funds	Both medications are hormonal and have: antihistamine, anti-inflammatory and antibacterial effects.
Validity	The effect of the drug can last up to 3 hours.	The period of validity of the analogue is not specified.
Appointments	The drugs are used for infectious and inflammatory diseases of the eyes and ears.
Prohibitions	Medicines are not prescribed for tuberculosis, viral or fungal infections and tissue integrity disorders.
Age limits	Not until 7 years old.	Do not use until 8 years of age.
Restrictions during pregnancy and lactation	Prohibited.
Negative consequences	The drugs may cause a burning sensation or tissue irritation.
Excess dose	The development of a negative reaction that is dangerous for the body is unlikely.	Growth retardation in children is possible.
Dosing features	Apply 2-3 drops 2 to 4 times every 24 hours. The course should not be more than 7 days.	3-4 drops are injected into the ears up to 3 times every 24 hours. Course up to 5 days.
Combined treatment	It is forbidden to combine with antibiotics.	Cannot be combined with antibiotics and hormonal medications.
Special recommendations	The drug can cause severe fungal or viral infections.	In severe pathologies, it is allowed to use drops for up to 2 weeks, but only as directed by a doctor.
Storage features	Storage temperature should be between 3 and 25 degrees. In a sealed form, the drug is valid for 2 years, and after opening no more than 30 days.	Storage temperature range from 3 to 25 degrees. The shelf life is 3 years.

The funds are close in therapeutic action and effectiveness. At the same time, the advantage of the original is the inclusion in the composition of two types of antibiotics, as a result of which Sofradex has a more pronounced antibacterial effect.

Combinil-Duo

An analogue of Combinil-Duo is produced by an Indian pharmaceutical company in the form of drops. The drug, like Sofradex, is used for infectious and inflammatory diseases of the eyes and ears.

Comparison table:

Basic data of medicines	Drug names
Sofradex	Combinil-Duo
Solution type	The tool is represented by a transparent liquid that has the smell of alcohol.	The drug is released in the form of transparent drops, a yellow tint is possible.
Vial volume	5 ml. Glass bottle, there is a dropper dispenser.	5 ml. The bottle is made of plastic and equipped with a dropper.
Main elements	Framycetin, gramicidin and dexamethasone.	Dexamethasone and ciprofloxacin.
Effects of funds	Has antihistamine, anti-inflammatory and antibacterial effects.	The analogue, like the original, is hormonal and has an identical therapeutic effect.
Validity	The effect of the drug can last up to 3 hours.	The drug begins to act in 30 minutes, and its effect lasts up to 3 hours.
Appointments	The drugs are used for infectious and inflammatory diseases of the eyes and ears.
Prohibitions	Medicines are not used for tuberculosis, viral or fungal infections and tissue integrity disorders.
Age limits	Not until 7 years old.	Analogue is prohibited to use under 18 years of age.
Restrictions during pregnancy and lactation	Drops cannot be used.
Negative consequences	May cause burning sensation or tissue irritation.	The remedy can provoke congestion and soreness in the ears.
Excess dose	The development of severe poisoning, with the abuse of both medicines, is unlikely.
Dosing features	Apply 2-3 drops 2 to 4 times every 24 hours. The course should not be more than 7 days.	Enter 4 drops up to 2 times every 24 hours for no more than 7 days.
Combined treatment	It is forbidden to combine with antibiotics.	Do not combine with hormonal agents and antibiotics.
Special recommendations	Medication can cause severe fungal or viral infections.
Storage features	The storage temperature of the considered funds should be from 3 to 25 degrees. In a sealed form, the drug is valid for 2 years, and after opening no more than 30 days.

The disadvantage of the analogue is the prohibition on its use in pediatrics. In terms of other characteristics, Combinil-Duo is close to the original.

Norfloxacin

The analogue of Sofradex for the ear, Norfloxacin, is a Russian remedy that can only be purchased with a prescription.

Comparison table:

Basic data of medicines	Drug names
Sofradex	Norfloxacin
Solution type	The tool is represented by a transparent liquid that has the smell of alcohol.	The analogue is released in the form of transparent drops.
Vial volume	5 ml. Glass bottle, there is a dropper dispenser.	5 ml. Unlike the original, the bottle is made of transparent glass. A dropper is also included.
Main elements	Framycetin, gramicidin and dexamethasone.	Norfloxacin.
Effects of funds	Has antihistamine, anti-inflammatory and antibacterial effects.	Destroys bacterial infection.
Validity	The effect of the drug can last up to 3 hours.	The duration of the therapeutic effect is up to 12 hours.
Appointments	Used for infectious and inflammatory diseases of the eyes and ears.	Diseases of the eyes and ears of a bacterial nature, as well as before manipulations on these organs.
Prohibitions	It is forbidden for tuberculosis, viral or fungal infection and tissue damage.	It is impossible in case of violation of the state of blood vessels, pathologies of the kidneys and liver in severe form, as well as in case of epilepsy.
Age limits	Not until 7 years old.	Banned under 12 years old.
Restrictions during pregnancy and lactation	Drops cannot be used.	The remedy is not prescribed, like the original.
Negative consequences	May cause burning sensation or tissue irritation.	When used topically, adverse reactions are rare.
Excess dose	The development of severe poisoning, with drug abuse, is unlikely.	Poisoning with medication (when swallowing a solution) is manifested by symptoms of moderate severity.
Dosing features	Apply 2-3 drops 2 to 4 times every 24 hours. The course should not be more than 7 days.	Enter 1-2 drops up to 4 times every 24 hours. The duration of treatment is determined by the doctor.
Combined treatment	It is forbidden to combine with antibiotics.	Complex therapy is possible with the permission of a doctor.
Special recommendations	Sofradex can cause severe fungal or viral infections.	It is forbidden to use drops for a long time without the permission of a doctor.
Storage features	Storage temperature should be between 3 and 25 degrees. In a sealed form, the drug is valid for 2 years, and after opening no more than 30 days.	Store drops at temperatures between 3 and 25 degrees. In a sealed state, the drug is valid for 2 years, after opening for 10 days.

The analogue, unlike the original, has only antibacterial activity. In this regard, the tool is less popular than Sofradex.

Otofa

The French analogue of Otofa is produced only in the form of ear drops. The drug, like Sofradex, can only be purchased with a prescription form.

Comparison table:

Basic data of medicines	Drug names
Sofradex	Otofa
Solution type	The tool is represented by a transparent liquid that has the smell of alcohol.	The drops have a rich, bright orange color.
Vial volume	5 ml. Glass bottle, there is a dropper dispenser.	10 ml. A glass bottle with a dispenser attachment.
Main elements	Framycetin, gramicidin and dexamethasone.	Rifamycin.
Effects of funds	Has antihistamine, anti-inflammatory and antibacterial effects.	It has a pronounced antibacterial effect.
Validity	The effect of the drug can last up to 3 hours.	The period of action of the drops is not provided.
Appointments	Used for infectious and inflammatory diseases of the eyes and ears.	The presence of a bacterial infection in the ear or before manipulation of the organ.
Prohibitions	It is forbidden for tuberculosis, viral or fungal infection and tissue damage.	Do not use in case of intolerance to the composition.
Age limits	Not until 7 years old.	None.
Restrictions during pregnancy and lactation	Drops cannot be used.	The use of an analogue is allowed, but after the permission of a doctor.
Negative consequences	May cause burning sensation or tissue irritation.	Allergic symptoms such as itching, tissue swelling or rash.
Excess dose	The development of severe poisoning, with drug abuse, is unlikely.	Poisoning is excluded with local use.
Dosing features	Apply 2-3 drops 2 to 4 times every 24 hours. The course should not be more than 7 days.	The dosage of drops is set according to age. The course lasts up to 7 days, no more.
Combined treatment	It is forbidden to combine with antibiotics.	The possibility of using an analogue in combination with other medicines should be checked with a doctor.
Special recommendations	Sofradex can cause severe fungal or viral infections.	The preparation dyes clothes in a reddish color, while stains cannot be removed.
Storage features	Storage temperature should be between 3 and 25 degrees. In a sealed form, the drug is valid for 2 years, and after opening no more than 30 days.	Store drops at a temperature not exceeding 25 degrees. Shelf life up to 3 years.

Otofa, unlike Sofradexa, has only antibacterial activity, and the drug can only be used to treat ears. In addition, the product stains the skin and clothing orange. In this regard, the analogue is less popular than Sofradex.

Otolorin

The Russian substitute Otolorin, unlike Sofradeksa, can be bought freely. The drug is used only for ear pathologies.

Comparison table:

Basic data of medicines	Drug names
Sofradex	Otolorin
Solution type	The tool is represented by a transparent liquid that has the smell of alcohol.	Transparent and slightly yellowish liquid with an alcoholic odor.
Vial volume	5 ml. Glass bottle, there is a dropper dispenser.	10 ml. Available in glass bottles. Dispenser attachment included.
Main elements	Framycetin, gramicidin and dexamethasone.	Boric acid and procaine.
Effects of funds	Has antihistamine, anti-inflammatory and antibacterial effects.	Has a disinfecting, analgesic and local irritant effect.
Validity	The effect of the drug can last up to 3 hours.	The action lasts up to 12 hours. In this case, the active substances are removed from the body for 1 week.
Appointments	Used for infectious and inflammatory diseases of the eyes and ears.	Ear pathologies, including those of an infectious nature.
Prohibitions	It is forbidden for tuberculosis, viral or fungal infection and tissue damage.	In case of allergies, violation of the integrity of the tympanic membrane and with severe renal failure, an analogue is not prescribed.
Age limits	Not until 7 years old.	Not prescribed for up to 1 year.
Restrictions during pregnancy and lactation	Drops cannot be used.	It is not advisable to use the drug.
Negative consequences	May cause burning sensation or tissue irritation.	The drops can cause itching, irritation and headache.
Excess dose	The development of severe poisoning, with drug abuse, is unlikely.	With long-term treatment and with a large dose, the classic signs of poisoning appear.
Dosing features	Apply 2-3 drops 2 to 4 times every 24 hours. The course should not be more than 7 days.	The dosage of the analogue depends on the age. In this case, the duration of the manipulations should not be longer than 1 week.
Combined treatment	It is forbidden to combine with antibiotics.	Complex therapy is possible with the permission of a doctor.
Special recommendations	Sofradex can cause severe fungal or viral infections.	The analogue is strictly forbidden to use if the integrity of the eardrum is violated.
Storage features	Storage temperature should be between 3 and 25 degrees. In a sealed form, the drug is valid for 2 years, and after opening no more than 30 days.	Storage features are identical to the original, but the shelf life when unopened is 3 years. After opening, the product can be used for 30 days.

Otolorin is inferior in effectiveness to Sofradex, but attracts attention with a long therapeutic effect and the possibility of using it from a year.

Price of funds

An analogue of Sofradex for the ear can be bought at any pharmacy. At the same time, depending on the point of sale, the price of non-medications may vary.

The following are approximate drug price ranges:

List of medicines	Vial volume or number of doses	Minimum price	Maximum price
Sofradex	5 ml.	398 r	RUB 512
Garazon	5 ml.	RUB 98	240 RUB
Combinil-Duo	5 ml.	543 r	686 r
Norfloxacin	5 ml.	157 r	294 r
Otofa	10 ml.	172 r	233 r
Otolorin	10 ml.	189 r	RUB 258

Sofradex, due to its three-component composition, has a pronounced antibacterial and anti-inflammatory effect, and at the same time is an almost safe remedy. The analogs considered in the article are inferior to the original in action, and also some drugs are used only for the treatment of ear pathologies.

Author: Kotlyachkova Svetlana

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