Norepinephrine is also called the hormone of rage and courage. Its production is carried out by the adrenal glands. When the patient is stressed, the adrenal glands instantly release this substance to the psychoemotional shock. In the process of receiving this hormone, a person feels self-confidence and courage, feels the ability to exercise.
Norepinephrine is produced from the amino acid tyrosine. After nervous tension, the hypothalamus releases corticotropin into the bloodstream. When the substance enters the adrenal glands, the amount of hormones increases. Adrenaline and norepinephrine are needed for the proper functioning of internal organs. If they are not enough, then the person will be defenseless against danger.
Overview of Norepinephrine
It is not a simple hormone, but a CNS neurotransmitter. Its content increases significantly if a person is in a stressful situation or in a state of shock.
The hormonal surge causes an increase in blood pressure and narrows the lumen between the vessels. After that, the neurotransmitter acts for a short period of time (the action time is almost 2 times less than that of adrenaline).
The main functions include the following:
- brake modulator;
- stabilizes blood pressure and respiration;
- regulates the endocrine system;
- improves the functional state of the body;
- promotes the manifestation of higher feelings.
In addition, noradernaline has other important functions:
- increases oxygen consumption;
- increases the content of glucose in the bloodstream;
- accelerates lipolysis and protein breakdown.
It is important to maintain a balance of adrenaline and norepinephrine. Deviations in the direction of increase or decrease are fraught with adverse consequences for the body.
Hormone synthesis
The effect of this neurotransmitter is very similar to adrenaline. They are interconnected. The synthesis is carried out from tyrosine. Every day, along with food products, a significant amount of this amino acid enters the body. Due to various processes, tyrosine begins to break down into small particles. One of them is Dofa. Then, with blood, it enters the brain, where it becomes a consumable for the formation of Dopamine. He synthesizes this neurotransmitter.
Purpose
This substance is the main mediator in the central nervous system, which controls the body in the event of danger, physical or psycho-emotional stress. Adrenaline and norepinephrine trigger a response that prompts a person to take drastic action. At this time, anxiety decreases, aggression increases and a surge of strength is noted.
In the process of the release of the hormone, the vessels narrow and adrenaline rises, tachycardia is observed. Along with this, under the influence of norepinephrine, the bronchi can expand and the functioning of the digestive tract can stop in order to save energy.
This neurotransmitter plays an important role in the human body. In his absence, he is defenseless and unable to carry out the functions of self-preservation. However, the production of a mediator is carried out not only during psychoemotional stress. It helps to feel joy and high spirits. Norepinephrine directly affects the work of the body in a stressful situation.
Positive and negative impact
The neurotransmitter promotes better absorption of glucose in the muscles, a surge of strength. Brain function is stabilized, memory and thinking are improved. The hormone has a certain cosmetic effect on the body.
With prolonged exposure, a blush is formed, minor mimic wrinkles disappear. Norepinephrine is predominantly observed in predators. Their amount significantly exceeds the level of adrenaline.
During the production of the neurotransmitter, vasoconstriction occurs, which leads to chaotic mental activity. In such a state, it is extremely difficult to concentrate. Suspiciousness, anxiety is observed. Visual disturbances, tinnitus are noted. At times, it increases in the process of watching action movies or engaging in dangerous sports.
With constant emotional outbursts, you need to stay calm. Otherwise, the following difficulties may appear:
- malfunctions of the heart and blood vessels;
- disturbances in the functioning of the central nervous system;
- disorders of the gastrointestinal tract.
With an increase or decrease in hormones, various pathological processes inside the body can occur. In this regard, it is necessary to prevent an imbalance in the neurotransmitter, otherwise it can provoke unpleasant consequences, which will be difficult to get rid of.
The consequences of imbalance
The synthesis of this neurotransmitter leads to the formation of adrenaline. The importance of the balance of hormones within the human body, produced by the adrenal glands, is difficult to overestimate. Its disadvantage is associated with depressed state. The symptoms of imbalance are quite pronounced.
Thus, when the content of the hormone is increased, it causes anxiety, sleep disturbances. A sudden rise in neurotransmitter levels can trigger panic attacks.
Lack of hormone in the bloodstream will be reflected in apathetic state, malaise, indifference to what is happening. It is observed that:
- People who have acquired lethargy syndrome have low hormone levels.
- Migraine is also a consequence of a lack of catecholamine.
- In Alzheimer's and Parkinson's diseases, norepinephrine is often an adverse triggering factor.
It is necessary to control the content of adrenaline and norepinephrine in the body, since an imbalance can provoke complex adverse effects in the work of internal organs.
The difference between the two hormones.
These hormones, which have similar names, have many differences. A sudden increase in the level of adrenaline inside the body has a more negative effect:
- mood swings;
- load on the heart and blood vessels;
- irritability.
Adrenaline is called the fear hormone because it often provokes a person to take decisive action and, in certain situations, calls for a fight. The proper effect can be achieved by playing sports. In other cases, an increase in adrenaline can be disastrous for the whole body. After a hormonal surge, euphoria is often noted.
Norepinephrine is not significantly different from adrenaline. It is synthesized in the process of using any favorite product in food or listening to music. Euphoria appears much less frequently. At the same time, changes are noted within the body:
- increased heart rate;
- increase in blood pressure;
- vasoconstriction;
- change in the rhythm of breathing;
- disruption of the digestive tract.
With the proper ratio, hormones have a positive effect on the body, add strength for subsequent activities. It must be borne in mind that the body needs rest, therefore, in order to obtain strong emotions, one should not deplete the body.
The Importance of Normal Norepinephrine Levels and How to Balance It
Adrenaline and norepinephrine are considered to be the principal hormones within the human body. The production of the second is mainly carried out in the brain, and then in the adrenal glands. When any threat appears, corticotropin is released into the brain, which acts as a catalyst in the process of hormone synthesis.
With a high content of the mediator, adrenaline increases, which affects the work of hearing, vision, and mental activity.
Lack of hormone can plunge into despondency, lethargy.
The proper tone and measured existence are achieved only if there is a balance within the body.
To build norepinephrine, the presence of phenylalanine and tyrosine is necessary. In this regard, an increase in the content of this component is achieved through the inclusion of certain food products in the diet. In addition, naps help boost hormone performance.
To regulate the balance of hormones, medications are often used, which help to eliminate the depressive state. The drugs of the group of selective inhibitors are often used. These drugs have a small list of side effects, but at the same time, their use often leads to positive changes.
In the list of medications that allow you to increase the content of norepinephrine inside the body, the following funds are allocated:
- Norepinephrine;
- Norepinephrine agetane;
- Hydrotartrate;
- Serotonin.
Various antidepressants contribute to the normalization of hormone levels by regulating the sensory state. The main emphasis in therapy should be placed on following the implementation annotation and medical prescriptions. Paroxetine is characterized by a strong effect, it blocks the effect of adrenergic receptors. Norepinephrine drugs do not give a pathological effect on metabolic processes and do not worsen the general condition of internal systems.
It is possible to use the above medications directly under the supervision of a doctor, since sudden drops in norepinephrine content can provoke complex and irreversible adverse effects.
Inside the human body, there are physically active elements that have a significant impact on the course of many physiological processes. These include catecholamines, which are mediators and hormones (adrenaline and norepinephrine). They are responsible for the emotional state, directly take part in mood formation and affect the body in the presence of a depressive state or stress situations. The main hormone that determines mood is norepinephrine. It also has the name of the hormone of courage and rage. Any deviation in the direction of increasing or decreasing the content of norepinephrine inside the body can provoke complex adverse and irreversible consequences.
