Antidepressant Ixel( Milnacipran is an international name) is often used in depressive states, anxiety disorders and malfunctions in the nervous system.
The drug normalizes the general condition, improves the psyche and promotes rapid recovery of the body.
The preparation is available in the form of capsules with gelatinous structure, the size range of which is № 4. The capsules have an orange-colored lid with a pink tinge, on the surface of the capsules there is a black print "IXEL".Inside the capsules there is a powder mixture with a white or almost white color, they are contained in blisters of 14 pieces. In packages from a cardboard basis contains 2 or 4 blisters.
Content of
Ingredients
- Features of
- Pharmacological properties of
- Indications and contraindications for taking
- How to take medicine
- Overdosage and side effects
- Special instructions
- Practical experience of using
- Cost
Features of composition
The composition includes the following components:
- the main active ingredient is milnacipran hydrochloride;
- calcium hydrophosphate dihydrate;
- carmellose calcium;
- povidone K30( polyvidone K30);
- silicon dioxide colloidal anhydrous;
- magnesium stearate;
- talcum powder.
Components of the shell:
- titanium dioxide( E171);
- iron oxide red( E172);
- iron oxide yellow( E172);
- gelatin.
Pharmacological properties
Ixel is an antidepressant with a wide range of effects. Refers to selective inhibitors with a re-uptake of monamine - serotonin and norepinephrine. This drug does not have a sedative effect. During the use of the medicine, the following effects on the body are observed:
- , a physiological improvement of sleep occurs;
- is insomnia;
- improves memory;
- does not adversely affect cognition;
- does not adversely affect the work of the heart, blood pressure, which is especially important for the elderly, who for a long period take corticotropic drugs.
After oral administration, Ixel is rapidly absorbed. The level of bioavailability of the drug is almost 85%, while the bioavailability does not depend on the nature and mode of food intake.
The highest level of concentration in the blood occurs approximately 120 minutes after the application of the drug. After the medication is reused, the equilibrium state can be reached in about two to three days. The degree of protein binding can be about 13%.
Drug withdrawal occurs within 16 hours. The main excretion occurs through the kidneys, almost 90% of the accepted dosage.
Complete elimination of the drug occurs within 2-3 days.
Indications and contraindications for the admission
The drug Ixel is prescribed to be used during therapy of depressive states and anxiety disorders with different 
severity.
Absolute contraindications for the use of the drug include the following conditions and disorders:
- , it is not necessary to use the drug for children and adolescents under the age of 15, because there is no clinical information on the effect of constituent elements on the children's body;
- is contraindicated in taking the drug concomitantly with selective and non-selective monoamine oxidase( MAO) inhibitors of type B, Sumatriptan;
- in case of hypersensitivity to the constituents of the preparation.
The following conditions are relative contraindications:
- for disorders of the urinary tract obstruction type, especially for prostate disease in men, with adenoma;
- to pregnant women;
- during breastfeeding;
- is not recommended for taking the drug with epinephrine, noradrenaline, clonidine and its derivatives;
- it is not necessary to use the drug at the same time with inhibitors of selective type MAO type A, digoxin.
How to take medicine
Ixel is taken orally, in addition capsules are washed down with a sufficient amount of water.
The average daily dosage should be about 100 mg. Capsules should be taken in the morning and closer to dinner in two divided doses. Depending on the severity and severity of the disease, the dosage of the drug may be increased to 250 mg.
Antidepressant Ixel is recommended to be taken while taking food. The duration of therapy for each patient is determined individually.
Overdose and Adverse Events
The following symptoms of overdose may occur when taking an increased dose of the drug:
- excessive sweating;
- attacks of nausea;
- disorder of the stool, namely the appearance of constipation;
- vomiting.
In these cases, it is recommended that gastric lavage be performed and further symptomatic treatment is provided.
If the drug has been taken at a dosage of more than 800-1000 mg at a time, the risk of tachycardia, difficulty breathing, may increase.
When taking a very high dose from 1900 to 2800 mg and if other psychotropic medications are additionally taken, there may be a violation of consciousness, hypercapnia and drowsiness, and the above symptomatology also arises.
The following unpleasant symptoms may occur during application:
- severe dizziness;
- feeling of anxiety;
- headaches;
- muscle tremor;
- appearance of nausea;
- vomiting;
- disorder of the stool, namely constipation;
- increased dryness in the oral cavity;
- occurrence of difficulties in urination;
- increased sweating;
- may cause a rash on the skin;
- increased heart rate.
Special instructions
When using the drug, it is desirable to pay attention to the following important features:
- antidepressant Ixel is recommended to take with care in the presence of prostatic hyperplasia( adenoma);
- during arterial hypertension, with convulsive seizures and cardiomyopathy, the drug is taken with extreme caution;
- should be prescribed no earlier than 2 weeks after discontinuation of MAO inhibitors;
- from withdrawal of the drug before starting the intake of MAO inhibitors should take at least a week;
- for the period of therapy with a drug should refrain from doing exercises that require increased attention.
Practical experience of application of
Review of our expert and testimonials of the visitors of the site Neurodec about the preparation of Ixell.
Ixel is an antidepressant that helps to quickly restore the nervous system. Its use makes it possible to get rid of neuroses, depressions, mental disorders, relieve insomnia and excitability, which has arisen on nerves.
Often this remedy is prescribed under stress, in cases of severe overwork and overstrain of the nervous system.
Usually, therapeutic treatment continues until a beneficial effect. Before taking the drug, it is worth consulting in a doctor, because the medicine causes side effects and has contraindications.
Doctor therapist, site expert Neurodok
Lately she became very nervous, apparently hard problems at work and in the family made themselves felt. As a result, I became very irritable, I fell into constant depression, and even serious problems arose with sleep.
After all these problems, I had to turn to a therapist. After the examination, the doctor recommended taking Ixel. I took it according to the instructions, and in a month I felt much better.
Irina, 28 years old
After the death of my mother, I began to feel that I have serious problems with the nervous system. I began to attend frequent depressions, lost the desire to rejoice and just live a full life. Even my children and husband could not help me at that time.
After a long persuasion of her husband, I still decided to go to see a doctor. After consultation, the doctor noted that I have a nervous system disorder and recommended taking Ixel. I took it for about 2 months, but after a week I noticed improvement, and after 2 months the depression completely disappeared.
Maria, 39 years old
Cost
The packing price of Ixel with the number of capsules 56, with a dosage of 25 mg is 1,700 rubles, No. 56 with a dosage of 50 mg is 2700 
rubles, there are also analogues of the drug:
- Adepres;
- Closet;
- Xset;
- Parelax;
- Paroxin;
- Rexetin.
