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Anticonvulsants: a list of the best for epilepsy and convulsive seizures

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anticonvulsants Drugs anticonvulsant group used as a means to eliminate pain symptoms and muscle spasms, preventing the transition from the state of pain attacks to convulsive and epileptic manifestations.

Activation of a nerve impulse simultaneously by a group of certain neurons is similar to a signal given by motor type neurons in the cerebral cortex. In the event of a lesion of this type, the nerve endings are not manifested in tics or convulsions, but cause pain attacks.

The aim of using anticonvulsant drugs is to eliminate pain or muscle spasms without provoking oppression of the central nervous system. Depending on the degree of complexity of the disease, these drugs can be used from several years prior to lifetime use in severe chronic or genetic forms of the disease.

Attacks of convulsive activity are associated with an increase in the degree of excitation of nerve endings in the brain, usually localized in certain areas of its structure and diagnosed when the condition is characteristic of the onset of convulsive syndrome.

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The cause of seizures may be a deficiency in the body of the necessary chemical elements, for example magnesium or potassium, pinching of the muscle nerve in the canal or a sharp prolonged exposure to cold. Deficiency of potassium, calcium or magnesium provokes failures in the transmission of signals to the muscles from the brain, as evidenced by the occurrence of spasms. impact on the neuron level

In the initial stage, the manifestation of neurological type development consists of local pain sensations emanating from the area of ​​the affected nerve cells and manifested by attacks of pain of varying strength and character of manifestation. With the course of the disease due to the development of inflammatory processes or muscle spasms in the area of ​​jammed nerve endings, the force of attacks increases.

In the case of early treatment with a specialist, a complex of medicines is used to treat patients, eliminating the causes and signs of nerve endings. Self-diagnosis and treatment does not allow choosing from a wide range of anticonvulsants the most suitable for relieving pain symptoms and eliminating the cause of unpleasant sensations.

Most of the drugs used in the treatment of seizures have combined effects, and there are many contraindications, on the basis of which, unauthorized administration and administration of these drugs can pose a health hazard to the patient.

When observed by a specialist, he assesses the performance of the prescribed drug in terms of its effectiveness and diagnoses the absence of pathological changes after its admission on the results of blood tests.

Contents

  • Fundamentals of anticonvulsant therapy
    • Basics of anticonvulsants
      • Imodiumbenes
      • Valproate sodium and derivatives
      • Barbiturates
      • Preparations based on benzodiazepine
      • Succiminides
    • Strike into nine convulsive "gates"
    • Practical experience of consumers
    • Time to collect stones

Basics of anticonvulsant therapy

complex treatment for convulsive manifestations includes groups of drugs of different principle of action, among them:

  • non-steroidal medicines with anti-inflammatory action , which reduce temperature and eliminate pain, and discomfort after elimination of inflammation;
  • tablets from neuralgia of the antiviral type , are used to prevent the appearance of disorders or reduce the degree of pain in the case of emergence;
  • preparations of the analgesic group , having an analgesic effect are used to eliminate pain sensations in strictly dosage amount to avoid occurrence of side effects;
  • means for the elimination of muscle spasms with manifestations of seizure character, related to the seizure group of muscle relaxants;
  • topical products in the form of ointments and gels for the treatment of affected areas or injections to stop the development of muscle spasms;
  • means, normalizing the work of the nervous system and sedatives ;
  • preparations of the anticonvulsant type , whose action is based on the elimination of pain symptoms by reducing the activity of nerve cells, these drugs are most effectively used when concentrating the source of pain in the brain or spinal cord, and with less for the treatment of peripheral nerve disorders.

Some of the prescribed drugs have the effect of inhibiting the development or prevention of allergic reactions.

The main groups of anticonvulsants

Anticonvulsant drugs are divided into several groups, the list of which is proposed below.

Iminostilbenas

Iminostilbeny, characterized by an anticonvulsant effect, after their use, the symptoms of pain and mood improvement are noted. The preparations of this group include: Finlepsin

  • Carbamazepine;
  • Finplesin;
  • Tegretol;
  • Amizepine;
  • Zeptol.

Valproate sodium and derivatives

Valproates, used as anticonvulsants and as iminostilbenes, contribute to improving the patient's emotional background.

In addition, with the use of these drugs, there are tranquilizing, sedative, and muscle relaxant effects. The preparations of this group include:

  • Acidiprol;
  • Valproate sodium;
  • Valparin;
  • Convoolex;
  • Epilim;
  • Apeilepsin;
  • Diplexyl.

Barbiturates

Barbiturates are characterized by a sedative effect, they help to lower blood pressure and have an Phenobarbital hypnotic effect. Among these drugs are most commonly used:

  • Benzobamyl;
  • Phenobarbital;
  • Benzamyl;
  • Benzoyl bromobamyl;
  • Benzoal.

Benzodiazepine-based drugs

Anticonvulsant drugs based on benzodiazepine have a pronounced effect, are used in the case of the appearance of convulsions in epilepsy and prolonged attacks of neuralgic disorders.

For these drugs, sedative and myorelaxate effects are characteristic, while using them normalizes sleep.

Among these drugs:

  • Clonazepam;
  • Antilepsin;
  • Clonopine;
  • Икторил;
  • Ravatryl;
  • Raised;
  • Rivotryl;
  • .

Succiminides

Anticonvulsants of this group are used to eliminate muscle spasms of separate organs in neuralgia. With the use of drugs in this group, sleep disturbances or nausea are possible.

Among the most commonly used tools are:

  • Pufemide;
  • Suxipep;
  • Succimal;
  • Ronton;
  • Etimal;
  • Ethosuximide;
  • Pycnolepsin.

Anticonvulsants used in leg cramps: Keppra

  • Valparin;
  • Xanax;
  • Diphenine;
  • Antinerval;
  • Keppra;

A blow to the nine convulsive "gates"

The main anticonvulsant drugs that are most often used for epilepsy, convulsive seizures and neuralgia of various origins:

  1. Finlepsin is used in cases of neurological diseases in the defeat of the trigeminal and glossopharyngeal nerves. Possesses properties of analgesic, anticonvulsant, antidepressant effects. The principle of the drug is based on the calming of the nerve membrane with a high degree of excitation by blocking the sodium channels. The drug is characterized by complete absorption of the walls of the intestine for a sufficiently long time. Among the contraindications to the use of the drug are poor tolerance of carbamazepine and increased eye pressure.
  2. Carbamazepine is used as an anticonvulsant for the treatment of trigeminal neuralgia, has an antidepressant effect. The beginning of the drug should be gradual as the dose of the previous drug decreases. Preparations with Phenobarbital content reduce the effectiveness of carbamazepine, which must be taken into account when prescribing Clonazepam for complex treatment.
  3. Clonazepam is characterized by an anticonvulsant effect and is used for the therapy of neuralgia with alternating attacks of myoclonic nature. Has a pronounced sedative and hypnotic effects. Possible side effects when using the drug are a violation of the functions of the musculoskeletal system, loss of concentration and mood disorders. The remedy removes the feeling of anxiety, has a hypnotic effect, sedative and relaxing action on the patient's body.
  4. Phenytoin is used in cases of convulsive status with an action based on retardation of nerve endings and fixation of membranes at the cellular level.
  5. Voltaren is used as an anticonvulsant for neurological disorders in the spine.
  6. Ketonal is used to reduce pain symptoms on the body, which have different sites of localization. When prescribing the drug for therapy, it is necessary to take into account the possible intolerance of the components and, as a consequence, the risk of developing a cross-type allergy.
  7. Valproate sodium is used in cases of attacks associated with the therapy of mild forms, the epileptic nature of muscle contraction. The drug reduces the production of electrical impulses sent by the nervous system from the cerebral cortex, normalizes the patient's psyche. Possible side effects of the drug are disorders of the digestive system, changes in the coagulability of blood.
  8. Benzobamyl , used for focal type attacks, is characterized by low toxicity and high efficiency in providing a sedative effect. Side effects of using the remedy are a state of weakness, a decreased emotional background reflected in the degree of activity of the patient.
  9. Phenobarbital is prescribed for children, has a sedative effect, is characterized by a hypnotic effect. It can be used in combination with other means, for example, with means for vasodilatation in disorders of the nervous system.

Practical experience of consumers

How is the situation with anticonvulsant therapy in practice? This can be judged from the reviews of patients and doctors.

I accept Carbamazepine as a substitute for Finlepsin, since a foreign analogue costs more, and a domestic preparation is excellent for therapy in my illness.

Since I tried both drugs, I can say about the high efficiency of both, however the significant difference in cost is a significant disadvantage of the foreign remedy.

Ivan

After several years of taking Finlepsin on the advice of a doctor, he changed it to Retard, since the specialist believes that this drug is more suitable for me. Complaints in the process of taking Finlepsin I did not have, but in Retard, in addition to a similar action, there is a soothing effect.

In addition, the drug is characterized by great convenience in use, because compared with analogues it should be taken not three times a day, but once.

Victor

The preparation Voltaren helps with pain syndromes of moderate severity. It is not bad to use it as a supplement to the main treatment.

Luba

Time to collect stones

A distinctive feature of anticonvulsants is the impossibility of rapid termination of their admission. With a noticeable effect from the effect of the drug, the cancellation period of its use is up to six months, during which a gradual decrease in the intake rate of the drug occurs.

Carbamazepine According to the widespread opinion of doctors, the most effective drug for the treatment of seizure activity is carbamazepine.

Less effective are drugs such as lorazepam, phenytoin, Relanium, Seduxen, clonazepam, dormicum and valproic acid, arranged in order to reduce their therapeutic effects.

It remains to add that anticonvulsants without prescriptions can not be obtained, which is good, because taking them irresponsibly is very dangerous.

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