Reference Book Of Medicines

What helps Nize - instructions for use

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Nyz

Page Contents

  • 1 Names - Description and Function of
  • 2 Forms of Issue
  • 3 When is Nyz used?
  • 4 Contraindications
  • 5 Instructions for use
  • 6 Adverse reactions
  • 7 Analogues
  • 8 Price
  • 9 Feedback on the use of

Nyz is a widely known drug from the NSAID group with a powerful analgesic, anti-inflammatory and antipyretic effect. Instructions for the use of tablets and gel Naise indicates that the main area of ​​application of the drug is the arrest of pain syndrome of a variety of etiology and localization( articular, dental, head, menstrual pains).In addition, the medication is used as part of the complex treatment of many diseases of the joints and spine and other conditions accompanied by the inflammatory process.

Naise - the description and the principle of action of

Nyz

The mechanism of action of Naise is based on the fact that its active substance - nimesulide, inhibits a special enzyme( COX-2), which is responsible for the production of inflammatory mediators( prostaglandins).As a result, the intensity of the inflammatory process decreases, the fever, pain and swelling disappear. The active ingredient, nimesulide, additionally exhibits antioxidant properties, preventing the formation of toxic products of oxygen decay.

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Local Naise forms quickly relieve pain in the area of ​​application, reduce swelling and morning stiffness of the joints and provide freedom of movement. When ingested, the active substance is absorbed for a short time from the gastrointestinal tract and penetrates into the synovial fluid and acid medium in the foci of inflammation. The drug is metabolized by the liver, excreted in the urine and bile.

Forms of release

Nyz

For ease of use, the anti-inflammatory agent is released in various dosage forms:

  • Nyz tablets - contain 100 mg of active nimesulide.
  • Tablets dispersed - contain 50 mg of nimesulide. Before taking them, dissolve in a small amount of water. Packing of both options - 10 pieces of tablets in a blister pack. In a cardboard bundle with a drug there are 2 blisters with tablets.
  • Suspension Naise - in 5 ml of the drug contains 50 mg of active ingredient. The suspension is packaged in 60 ml vials equipped with a dosage cap.
  • Gel Naise( 1%) - 1 g of gel contains 10 mg of active substance. The gel is produced in an aluminum tube of 20 and 50 g.

When is Naise used?

Nyz

Indication for the use of the drug are the following conditions:

  • inflammatory - degenerative diseases of muscles, joints and bones. In this list, a variety of pathologies - arthritis of various etiologies, osteoarthrosis, radiculitis, rheumatism, sciatica, lumbago, atralgia and myalgia.
  • osteochondrosis with radicular syndrome;
  • ankylosing spondylitis;
  • bursitis, an inflammatory process in the ligaments and tendons.

Nyzes are widely used to eliminate inflammation and pain in traumatic injuries of the musculoskeletal system and soft tissue bruises. Another area of ​​application - pain syndrome in the postoperative period and with pains of the most diverse genesis( for example, dental, head, menstrual).In addition, Nyz from the pain can be used as part of a comprehensive treatment of infectious diseases, as the drug exhibits antipyretic, analgesic properties and helps to cope with fever.

Contraindications

Because the drug belongs to the group of non-steroidal anti-inflammatory drugs, it has the same contraindications as most other NSAIDs. Nyz can not be used to stop heat and pain in the following conditions:

  • peptic ulcer and erosive lesions of the digestive tract;
  • pregnancy, lactation;
  • gastrointestinal bleeding;
  • hepatic or renal insufficiency;
  • children's age( up to 2 years);
  • individual intolerance to nimesulide.

With special care, the drug in tablets is prescribed for patients suffering from diabetes mellitus, hypertension, autoimmune diseases( systemic lupus erythematosus), heart failure.

In pregnancy and lactation, taking a drug from the NSAID group is prohibited, since the active substance adversely affects the course of pregnancy and fetal development. Medications with nimesudide are prohibited for use even at the stage of pregnancy planning. Do not take Naise and during breastfeeding, since the active substance can penetrate into the mother's milk.

Nyz in the form of a gel can not be recommended to people who have skin lesions in the field of application of an external remedy, or to those who suffer from skin infections and manifestations of dermatosis.

Instruction for use

The doctor Consultation of a physician

Instructions for use Naiz prescribes adults to take 1 tablet twice a day, preferably before meals. The maximum allowable daily dose of the drug should not exceed 400 mg( 4 tablets).

Disperse tablet before use should be dissolved in 1 tsp.water and then drink. In this case, the drug is recommended after eating.

Suspension can be drunk before meals or after eating, if it causes uncomfortable sensations in the stomach.

Before applying Nyaz gel, the affected area should be washed and dried. The drug is applied a thin layer on clean skin. The amount of gel varies according to the treated area. Frequency of application - no more than 4 times a day. The maximum period of use of the external means is 10 days.

The instructions for use indicate that the gel should not be rubbed into the skin during application, otherwise a burn can be obtained. The substance capsaicin, which is part of the gel, can provoke reddening of the skin and a feeling of heat and burning. If a strong irritation appears in the application area, the use of the gel is stopped. Sometimes in the field of processing, even after discontinuing the use of the drug, painful sensations may remain.

Use external medicine with caution, avoiding contact with mucous membranes and eyes. After the procedure, the tube with gel should be tightly closed with a cap and be sure to wash your hands with soap.

How many days can you drink Naise? The answer to this question is in the competence of the attending physician. Everything depends on the severity of the condition, the severity of the pain syndrome and the inflammatory process, as well as the presence of concomitant diseases and possible contraindications. Since the active substance of the drug - nimesulide has a negative effect on the gastric mucosa and can provoke the development of an ulcerative process, the drugs from the PVS group tend to be prescribed in short courses. On average, the duration of treatment by Naizom is 7-10 days.

Can Nyz be for children?

children

The use of the drug in children is appropriate with age restrictions. Any form of Naise can not be used in young children. Starting from 2 years of age and older, it is permitted to prescribe the drug in the form of a suspension for oral administration. The pediatrician calculates the required dose individually, taking into account the body weight and general condition of the child. Babies older than 3 years can be given dispersible tablets, at the age of 12 years and older, the drug is prescribed to children in the same dosage as adults.

Adverse reactions

nausea

The use of a drug from the NSAID group can cause a number of adverse reactions from various organs and body systems:

The sides of the digestive system when taking the drug inside are possible such manifestations as nausea, vomiting, abdominal pain, stool disorders( diarrhea).With prolonged admission Naiza, development of ulcers and erosive lesions of the gastrointestinal tract is not excluded.

From the side of the nervous system, judging by the responses of patients, headaches, dizziness, weakness often occur. On the part of the respiratory organs there is bronchospasm, dyspnea. Possible development of violations from the hemopoietic system( anemia, thrombocytopenia, leukopenia).The cardiovascular system can respond to the intake of the drug with hot flashes, heart rhythm disturbances, and heartbeat.

In case of individual intolerance to nimesulide, allergic reactions develop, which are manifested by skin symptoms( rash, hyperemia).In severe cases, the rapid development of an allergic reaction leads to anaphylactic shock, which requires the provision of emergency medical care.

When applying the gel, such reactions as itching, flaking, rash-like rash, transient discoloration of the skin are noted. But such manifestations do not require the discontinuation of the drug and with further use of the gel pass independently.

Overdose of

Enterosgel

Overdose Naiza can lead to severe consequences and is accompanied by a violation of kidney function, liver failure, seizures, increased blood pressure, respiratory depression, drowsiness and apathy. Sometimes the position of the patient is aggravated by the development of gastrointestinal bleeding. When an overdose of the patient is sent to a hospital where gastric lavage is done, sorbents( Enterosgel, Polysorb, Polypefan) and osmotic laxatives will be prescribed.

To avoid overdose, follow the instructions to the drug and do not exceed the maximum allowable daily dosage. The dose of medicine for the child should be calculated by the attending physician, taking into account the body weight, age, severity of symptoms and other individual characteristics.

Additional recommendations

contraindications

Nyz preparation should be used with extreme caution in patients suffering from cardiovascular pathologies, liver and kidney diseases, and dehydration of the body. It is not recommended to use this tool if there are pathologies of the organs of vision, metabolic disorders, diseases of the digestive tract, asthenic conditions.

For pathologies of the kidneys, the drug is approved for use only under the supervision of a physician. If the course of treatment lasts more than 7 days, it is necessary to monitor kidney and liver function. If there is a malfunction in their work, the Naise should be canceled and in the future not used in the treatment of drugs with nimesulide.

One of the side effects of Naise is the reduction of blood clotting, so it can not be administered to patients taking anticoagulants and having a tendency to bleed. You can not use this remedy for a disease such as hemorrhagic diathesis.

If such symptoms as vomiting, abdominal pain, darkening of the urine, jaundice of the skin, increased fatigue, changes in blood counts occur on the background of taking the tablets, the drug should be discontinued, since such symptoms indicate a toxic liver damage.

In the treatment of Naise, alcohol should be completely excluded, since methanol increases the toxic effect of the drug on the liver and significantly increases the risk of developing drug hepatitis.

Interaction with other drugs

Simultaneous reception of Naise with aspirin and other NSAIDs increases the risk of bleeding, as these drugs reduce the viscosity of the blood. The same effect is observed when Naise is combined with glucocorticosteroids. In addition, it is not recommended to prescribe Nyz concomitantly with cyclosporins, enhancing its nephrotoxic effects and Methotrexate.

Analogues of

Nimesil( powder, tablets) for children and adults - instructions for use and reviews

The structural analogues of Naise containing the same active substance( nimesulide) are the following preparations:

  • Actasulide;
  • Aponyl;
  • Mesulide;
  • Nimesil;
  • Nimesulide;
  • Prolid;
  • Floiled.

Neil gel analogues are external agents Diclofenac, Nimulide, Voltaren.

Price

In the pharmacy chain, any dosage form of Naise can be purchased without a doctor's prescription. But before using it, it is better to consult a specialist in order to timely identify possible contraindications and avoid undesirable complications. We will quote the average prices for the drug.

  • Nase gel 1%( 20g) - from 180 rubles;
  • Naise tablets( 20pcs) - from 200 rubles;
  • Nyz tablets are dispersible( 20pcs) - from 190 rubles;
  • Nase suspension( 60ml) - from 230 rubles.

Feedback on the application of

Review No. 1

Despite the abundance of side effects, most of the reviews about Naise are positive. Patients note its effectiveness in stopping the pain syndrome of various etiology and localization( dental, head, articular).

The use of pills suppresses painful symptoms for a period of 8 to 12 hours and allows you to lead a habitual way of life, work productively and sleep peacefully at night.

However, in the reviews, patients warn that it is impossible to constantly use an anti-inflammatory drug, especially in children. Regular application of tablets increases the risk of developing gastric ulcers and gastric bleeding, therefore, the drug should be treated with caution, accurately observe the recommended dosages and do not exceed the optimal duration of therapy.

Larissa, St. Petersburg

Review No. 2

Naise gel began to be used on the recommendation of a friend who had similar problems. I was tormented by pains in the spine that were given in the leg. Since morning I got up with great difficulty, because there was limited mobility of the joints, and there was numbness in the extremities.

Gel used twice a day, relief was felt on the second day of treatment. Gradually the pains receded, it became easier to move and get up in the morning. But, unfortunately, it can not be used for more than 10 days, since it can negatively affect the digestive system and provoke a stomach ulcer.

Oleg, Moscow

Review No. 3

Recently, in the garage, he stumbled awkwardly and strongly twisted his leg. She swelled quickly, blushed at the ankle, it hurt very much. The picture showed that there was no fracture, only a strong stretching of the ligaments.

At home, I suffered from severe pains, until my wife gave Naize a pill, then felt relieved. He began to treat the leg with a cream with anti-inflammatory action and drink Naise tablets.

A few days later, the swelling was asleep, and the skin began to acquire a normal color. Nayz is really a good anti-inflammatory. I only took it for a week, so I did not feel any side effects.

Elvira, Krasnodar

Review No. 4

With the drug Nyz is familiar for many years, and he helped me out in a variety of situations. Saved from toothache, painful menstruation, helped to cope with heat and headache for colds.

I think that it is in many respects even safer than other drugs from the same group of NSAIDs and, when properly administered, rarely causes side effects. So do not be afraid of a long list of contraindications, you need only take into account that this remedy can not be taken for a long time. Usually, to ease the condition, 3 to 5 days of treatment is enough.

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