Contents of the page
1 Action of the drug
Erius is an effective antihistamine drug that is used in treatmentallergies of different genesis. This selective blocker of antihistamine receptors of the body has an active active substance desloratadine, a metabolite of the loratadine known to everyone.
The main advantage of this new generation medicine is the complete absence of sedation, as a result of which the patient does not feel drowsiness and fatigue at all. In laboratory preclinical studies, it was found that pharmacological differences between active drug substances loratadine and desloratadine are absent.
Action of the drug
The pharmacological properties of the preparation describe in detail the instructions for the use of Erius. This drug has a long and very effective therapeutic effect and is an effective blocker of histamine peripheral receptors. Active medicinal substance desloratadine inhibits various reactions of an allergic nature, removes inflammation of the skin, nasopharynx, respiratory organs, effectively releases cytokines in the body of the patient with human allergy.
As a result of exposure to this drug, interleukins are fully incorporated and further release of chemokines. Thus, substances of histamine, prostaglandin, leukotriene are released in the patient's allergy. Chemical reactions also provoke the release of adhesion molecules.
The drug prevents the further development of allergies of any genesis, and also facilitates the course of the disease itself.
Erius:
- Provides effective antipruritic and antiexudative action;
- helps reduce capillary permeability;
- prevents various swelling and smooth muscle cramps.
As a third generation pharmaceutical product, Erius does not affect the central nervous system, does not affect the various psychomotor reactions of the patient's body and does not cause a feeling of drowsiness, unlike other antiallergic drugs. The effect of this drug begins within half an hour after taking the medication orally and lasts for a whole day.
Desloratadine is partially absorbed in the gastrointestinal tract, the concentration of this drug in the blood plasma is observed after half an hour after it enters the body of a patient with human allergy. The total concentration of desloratadine in the blood comes in thirty hours. In the body, the active drug dezloratadine actively binds to blood proteins by 87%.
Simultaneous food intake does not affect its further distribution. In the process of metabolism, the drug is hydroxylated to form 3-OH-desloratadine, which is combined with glucuronide. The drug does not inhibit glycoprotein.
From the body, the drug is excreted as a glucuronide compound with urine and calves.
Dosage form
The drug is available in coated tablets and in syrup. Tablets of the preparation have a blue shell and printed logo of the manufacturer. Each tablet contains desloratadine 5 mg. As an aid, dihydrate of hydrophosphate, cellulose, corn starch and talc are used.
Syrup for oral use contains 250 μg of active substance in one milliliter. Auxiliaries that are part of the syrup: propylene glycol, disodium edetate, sodium benzoate, liquid sorbitol, citric acid, dye and flavor.
Included in the syrup is a dosage spoon with a dosage of 2.5 ml and 5 ml. The syrup has a pleasant taste and aroma and is intended for the treatment of allergies in children of one year old.
Operating instructions, dosage
Before starting the therapeutic treatment with this medication, you need to know how to take Erius. The coated tablets are prescribed by the attending physician to adults and children over 12 years of age. A single dosage of the drug is 5 mg. The drug is taken one tablet once a day. The tablet should be swallowed whole and washed down with a small amount of water.
Children from one year are given syrup Erius. Up to five years - 2.5 ml of syrup( once a day).Children aged 6 years are prescribed 5 ml of syrup once a day. Children older than 12 years should take 10 ml of syrup per day for one dose.
Syrup can be taken at any time of the day, regardless of food. Before taking the medication, you should consult an allergist who will prescribe the correct individual dosage of the medication and the required course of treatment.
Overdose of
In the case of a minor overdose of the remedy, no symptoms have been clinically detected. If you accidentally take a large amount of a drug, you should immediately wash your stomach and take activated charcoal. The doctor can also prescribe symptomatic therapy in case of complications of health.
Indications for use
After oral administration of the antiallergic agent, Erius effectively blocks histamine receptors. In this case, the drug does not penetrate the blood-brain barrier. Due to its anti-inflammatory, antiallergic properties, this medication is prescribed by allergy specialists, both adults and children, from one year when various allergic reactions of various genesis manifest themselves.
Erius may be administered at:
- seasonal manifestation of plant bloom allergy;
- allergies to medicines;
- allergies to animal hair;
- dust allergies;
- with food allergies to various products;
- for allergy to insect bites.
The basis of inflammation in the patient's body can be acute atopic bronchospasm, release of prostaglandin, expression of selectin, production of cytokines.
The main indications for the use of the drug:
- atopic dermatitis;
- skin itching;
- allergic rhinitis;
- allergic cough;
- allergic nasal congestion;
- is an allergic skin rash;
- pollinosis;
- idiopathic chronic urticaria.
Side effects
Like any pharmaceutical product, this drug has its own minor side effects from various human body systems. Side effects have been observed clinically in some patients with allergies and producing appropriate treatment with this drug. Basically, patients complained of increased fatigue, headache, palpitation, tachycardia, dry mouth.
The main side manifestations when taking the medication are:
- diarrhea;
- insomnia;
- activity of hepatic enzymes;
- hepatitis;
- migraine;
- disorders from the gastrointestinal tract;
- disorders of the cardiovascular system.
Erius during pregnancy and lactation
Also, the medicine is very carefully prescribed during pregnancy and lactation. Clinically, on pregnant women, the effect of this drug was not detected. However, in the case of the appointment of Erius to a pregnant woman, the attending physician takes into account the ratio of benefit to the mother and the occurrence of a risk for the fetus to be born.
Any medicine taken during pregnancy is dangerous, because chemicals can cause the development of various pathologies and malformations in a future child. This medication is prescribed during pregnancy with great caution and only when exercising medical control over the patient's health.
When breastfeeding the drug is not prescribed. If, for any reason, the doctor insists on taking this medication as a nursing mother, the child must be transferred to artificial feeding.
Contraindications
Major contraindications:
- lactation;
- pregnancy;
- individual intolerance;
- children under one year old;
- hereditary fructose intolerance.
Erius is not assigned to hypersensitivity of the patient to the active drug desloratadine.
Interaction with other drugs
As a new generation drug, Erius practically does not interact with other drugs. Clinically, significant changes in the body of patients with the active substance desloratadine with other medicinal substances Azithromycin, Erythromycin, ketoconazole, cimetidine and Fluoxetine have not been registered. Until the enzyme, which would interact with desloratadine, was not clinically identified.
This gives a special advantage to the preparation of Erius before other antiallergic drugs. Obsolete antihistamines Suprastin, Diazolin and many others cause a pronounced sedative effect. Sometimes the constant drowsiness from taking antiallergic drugs interferes with full-fledged work and causes a lot of inconvenience.
Also in this case, you can not drive a vehicle. Erius does not cause any drowsiness and does not interfere with the psychomotor reactions of the body. With this medication the patient can safely work without feeling tired and sleepy.
Erius for children
To children Erius from an allergy is appointed from two years in the form of a syrup. The use of this histamine blocker for children under one year is not recommended. The safety of the use of this drug in the treatment of children under two years has not been established. In most cases, the runny nose of a small child is of an infectious nature.
As a rule, it is quite difficult to establish a differential diagnosis of rhinitis in a small child. It is necessary to carry out thorough analyzes, various laboratory tests of the respiratory system, in order to establish a child's allergic rhinitis. Corresponding results can serve as the reason for appointing Erius to children of two years in the form of syrup.
In case of prescribing this medication to the child, it is better to use in the treatment of syrup Erius, which has a pleasant taste and will not be unpleasant to the baby. The syrup has a pleasant taste and smell, it is completely safe. Dosage of the syrup should be prescribed by the attending physician, who knows all the features of the child's organism, the symptoms of an allergic reaction.
The individual dosage also depends on the weight and height of the child. In some cases, the syrup can be replaced with tablets in the shell, but it is necessary to divide the pill and give it to the child only as prescribed by the doctor. Adults can not take children! Before taking Eryus in syrup and tablets, be sure to show the child to a qualified allergist!
Analogues of
In some situations, Erius should be replaced in treatment for other, similar antihistamines. Like most drugs, Erius has its analogues, which are similar in interaction to the body. Below listed drugs are prescribed for such allergic manifestations, such as: allergic rhinitis, sneezing, itching in the palate, an allergic cough, discharge from the nasal cavity, skin itch, skin rash, stuffiness and swelling of the nose.
Each antiallergic drug has its own cost. Find out what is better than Erius in the treatment of allergic symptoms, the attending physician will help. Since Erius is a new generation drug, it can be replaced only among drugs of similar pharmacological action. The best drugs can affect each organism in their own way, so the choice of medicine is determined strictly by the doctor who knows all the features of the disease.
Analogues:
- Alerhomax;
- Desloratadine;
- Alerstop;
- Ds-lor;
- Dismantling;
- Lauratec;
- Eden;
- Fribrys.
Price
The cost of Erius in various pharmacy points can vary in a significant price range. The approximate cost of the drug in domestic pharmacies is 400-600 rubles.
This medication has proven itself in the treatment of various manifestations of allergies. Erius does not cause drowsiness, it does not interact with other medicines, effectively removes inflammation and removes allergy symptoms. This drug is completely safe and can be used in the treatment of children from one year.
Feedback on application
Review No. 1
I often suffer from seasonal allergies in late spring. Usually the allergy begins with a simple sneezing, itching in the nasopharynx. Then an allergic rhinitis is added to the unpleasant sensations. It starts intensified lacrimation, it is simply impossible to look at the light, so tears cover your eyes. The state is terrible, and I have been suffering for several years.
The first time I tried the treatment with Erius three years ago, and since then I always have it on hand every spring. This drug just brings me back to normal. Allergic rhinitis begins to pass on the fourth day of treatment with this medicine.
Erius is very effective and effective, while it has a minimum of adverse reactions and contraindications. I have not observed any side effects at myself. In addition, I like that, unlike old antiallergenic drugs of the Soviet period, Erius does not cause drowsiness at all.
Inessa, 27 years - Voronezh
Review No. 2
I have a hard time with allergies. In our home medicine chest, Erius is always there. We give growing children at the slightest manifestation of the rash for cold medicines, antibiotics, we are saved by this drug from insect bites.
Yes, and with his wife at the slightest signs of allergies we apply in the treatment of Erius. A little expensive for the price, but the medicine is worth it. Very effective drug. Perfectly removes a rash, itching. I recommend to all who suffer from allergy symptoms.
Kirill, 31-year-Rostov-on-Don
Review No. 3
My son fell ill no one knows what happened five years ago. First there were plaques on the skin and a small rash. Have addressed for the help in the allergocentre. The doctor has appointed or nominated to pass or take place analyzes, has taken allergens and has sent to hand over soskob skins. We thought that we would find something serious, but the analyzes showed nothing.
Then the doctor diagnosed atopic dermatitis, prescribed an anti-allergic diet, prescribed a corticosteroid ointment and Erius in tablets. The child was then 4 years old, but the allergist prescribed the drug in tablets. We treated our son completely according to her recommendations. The rash passed almost immediately, then the red swollen plaques on the skin began to disappear.
Literally in ten days the child was perfectly healthy. Since then, I buy Erius at the slightest manifestations of the allergy of the younger daughter and try to always keep this medicine in my home medicine cabinet.
Светлана, 39 years - Москва
Reviewed № 4
I liked the action of Erius. The drug is very strong, removes sneezing, nasal congestion, quickly removes skin rash at various allergies. The main thing is completely safe and does not cause sleep. Taking Erius, you can safely work in production as usual.
We have already learned how to make good antiallergic drugs. Often I use Erius in the treatment of allergies to insect bites in children, as well as when children suffer from atopic dermatitis, then for food, then for medicines, then for an ordinary cat. Erius wrote to my children an allergist, because they had to take allergens and pass various tests, revealing the child's allergen. A good drug of a new generation, very effective and strong. I recommend.
Boris, 45 years old - Krasnodar
