Reference Book Of Medicines

Pentalgin tablets - instructions for use, composition

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Pentalgin - instructions for use, reviews on the drug

Page Contents

  • 1 Pentalgin - Properties and Composition
  • 2 Indications
  • 3 Contraindications
  • 4 Side Effect
  • 5 Analogues
  • 6 Feedback on the use of

Pentalgin is a combined preparation that has an effective anti-inflammatory and analgesic effect. The therapeutic effect of the drug is due to the five main active components that make up its composition. Instructions for the use of tablets Pentalgin details its pharmacological properties and effects on the body. According to her, the drug has the ability to inhibit the synthesis of prostaglandins due to blocking in the central nervous system of an enzyme such as cyclooxygenase.

Pentalgin - properties and composition of

Pentalgin is a highly effective remedy for the elimination of severe pain of various etiological features. This non-steroidal and non-narcotic drug is able to cope with a severe pain syndrome, and also have a high anti-inflammatory and antipyretic effect. That is, this drug very quickly eliminates pain, various spasms, lowers the temperature and eliminates the focus of inflammation.

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Pentalgin - properties and composition The drug has analgesic, antispasmodic, psychostimulating properties and effectively blocks H1-histamine receptors. The drug is provided by the following medicinal substances:

  1. Drotaverine.

Effectively eliminates spasms of any kind, favorably affects smooth muscle, biliary-excretory pathways, genitourinary and vascular systems. The substance has a pronounced antispasmodic myotropic effect.

  1. Paracetamol.

Is a non-narcotic analgesic that effectively lowers heat and eliminates pain. Its analgesic and antipyretic effects are due to blockade of certain enzymes of the central nervous system, which leads to effective influence on the pain centers and regulates body temperature.

  1. Naproxen Naproxen.

An anti-inflammatory non-steroid component that quickly eliminates the inflammatory process, has an analgesic effect and is also able to reduce fever. The action of the substance is associated with the suppression of the enzyme cyclooxygenase, which regulates the synthesis of prostaglandins. Naproxen actively prevents the development of inflammation and pain.

  1. Caffeine.

Expands the blood vessels of tissues and muscles, beneficially affects the kidneys and heart, eliminates fatigue, drowsiness, increases physical and mental performance. Caffeine enhances the bioavailability and effect of analgesics that go into Pentalgin. It increases the permeability of barriers and increases the therapeutic effect of the drug. Caffeine has a tonic effect on the vessels of the brain.

  1. Pheniramine.

Is a blocker of histamine receptors. Effectively removes spasms and pains of a different nature, enhances the analgesic effect of paracetamol and naproxen.

Indications

What helps Pentalgin? The agent has a very wide range of applications. The drug is effective for headaches, with rheumatic pain, with pain after surgery. The main indications for the use of the drug:

  • What helps Pentalgin myalgia;
  • arthralgia;
  • toothache;
  • headache;
  • acute pain syndrome of different etiology;
  • Migraine.

Also, these medications are often prescribed:

  • for the complex therapy of acute respiratory viral infection and influenza;
  • at high temperature;
  • in the inflammatory process;
  • for muscle pain;
  • fever;
  • pain after injury;
  • pain after surgery;
  • pain in cholelithiasis;
  • in chronic holitsestit;
  • of renal colic.

The drug is a tablet. The maximum allowable dose of the drug is 4 tablets per day. It is important to know that prolonged use of tablets Pentalgin is able to induce drug dependence. It is not recommended to use the drug in treatment for more than seven days. In the case of such a need, it is required to monitor the functioning of the liver and kidneys, as well as the composition of the blood.

Contraindications

Contraindications Pentalginum Pentalgin can not be used during childbearing and breastfeeding. Also, the drug is not used in the treatment of children under 12 years. The main contraindications:

  • tachycardia;
  • myocardial infarction;
  • kidney failure;
  • disorders in the functioning of the liver;
  • polyposis of the nose;
  • bronchial asthma;
  • intestinal bleeding;
  • is an individual intolerance.

With care, it is necessary to take Pentalgine for elderly people, sick with diabetes, patients with epilepsy.

Varieties of the drug

Pentalgin H

Pentalgin H Preparation Pentalgin H includes sodium metamizole, phenobarbital, codeine, naproxen and caffeine. The medicine is available in tablets, in a cellular contour pack( 10 pieces).Phenobarbital provides a sedative effect, soothes the nervous system. Codeine blocks certain receptors and effectively removes pain. The drug is a non-narcotic analgesic. Has analgesic effect and effectively copes with pain in various diseases.

Pentalgin H is used to eliminate any pain and fever. It is used after operations, with a cold, neuralgia, myalgia, radiculitis and other diseases. The drug effectively removes toothache, muscle pain and quickly eliminates migraines.

Medication is contraindicated in case of:

  • Medication is contraindicated of individual intolerance:
  • peptic ulcer;
  • blood diseases;
  • disorders of the liver and kidneys;
  • alcohol intoxication;
  • acute myocardial infarction;
  • heart rhythm disturbances;
  • attacks of bronchial asthma;
  • glaucoma;
  • traumatic brain injury;
  • high intracranial pressure;
  • hypertension;
  • pregnancy;
  • of lactation;
  • in children under 12 years.

Pentalgin icn

Pentalgin icn There is also such a medicinal variety as the preparation Pentalgin icn. In its composition this drug contains paracetamol, caffeine, phenobarbital, codeine phosphate, sodium metamizole. It is a combined medicine that has an anti-inflammatory, analgesic and antipyretic effect. The drug effectively blocks pain, affecting the centers of inflammation. Reduces the peristalsis of the intestinal sphincters, relaxes the smooth muscles, eliminates spasms.

The medicine is indicated for the elimination of pain syndrome of any etiology, it is used for headaches, for colds, for rheumatism, after surgery. Also the remedy perfectly eliminates toothache and muscle pain. The drug can not be used for a long time and uncontrolled.

Contraindications:

  • alcoholic intoxication pregnancy;
  • lactation;
  • child's age;
  • anemia;
  • respiratory depression;
  • arrhythmia;
  • alcohol intoxication;
  • leukopenia;
  • bronchial asthma;
  • hypertension;
  • susceptibility to drug components;
  • kidney failure;
  • liver disease;
  • glaucoma.

Side effect of

The drug is very well tolerated by the body and rarely causes side effects. When taking medication in rare cases, such manifestations as:

  • nausea;
  • vomiting;
  • abdominal pain;
  • sleep disturbance;
  • anemia;
  • vision impairment;
  • heart rate failure;
  • noise in the auricles;
  • increased intracranial pressure;
  • stool disorders;
  • allergic reaction.
Pentalgin for pain: recommendations on the use of Pentalgin for pain: recommendations for use
  1. Do not use Pentalgine with other non-narcotic analgesics, with aminofenazone, since the joint intake of these medicines causes an increase in toxicity in the body. The paracetamol, which is part of the drug, enhances the effect of anticoagulants and reduces the effect of enzyme agents.
  2. The treatment with pentalgin during alcoholic intoxication is forbidden, since the codeine included in the medicine strengthens the oppressive effect of alcohol on the central nervous system.
  3. Pentalgin enhances the action of such drugs as Griseofulvin, Phenothiazine, Doxycycline, as well as estrogens and antidepressants. The effect of tranquilizers and sedatives increases the analgesic effect of Pentalgin.
  4. The use of the drug in large doses and its long-term use causes drug dependence. The drug should be taken one tablet 1-3 times a day. The tablet is swallowed whole and washed down with enough drinking water. Many patients are interested in - through how much is Pentalgin? All active components of the drug are quickly absorbed into the stomach tissues and enter the bloodstream, after which they begin their effects in the body. Therapeutic and analgesic effects can be felt within 10-15 minutes after the use of one tablet of the drug.
  5. The intake of the drug does not depend on the intake of food. The maximum dose( single dose) can be in special cases, two tablets. Duration of treatment is usually prescribed for a period of 5-7 days. In case of acute need, taking the drug can be continued under the supervision of the attending physician and regular monitoring of blood counts. Pentalgin can not be used in the treatment of children under 12 years old.

Overdose

Overdose In the event of an overdose of the drug, vomiting, nausea, weakness, decreased heart rate and blood pressure may occur. Also, an overdose manifests an allergic reaction, depression of the central nervous system.

Application in pregnancy and lactation

Fetal bearing requires a pregnant woman to pay special attention to her health. Any intake of medications can cause a risk for the future child's development of various pathologies and abnormalities. Pregnant should be as cautious as possible with medication. Any desire to take medication should be agreed with a gynecologist who knows the features of the course of pregnancy.

Application in pregnancy and lactation Preparation Pentalgin and its variants Pentalgin N, Pentalgin icn can not be used during pregnancy! Instruction to the drug from manufacturers of the drug prohibits its use during the period of bearing the child at any stage of pregnancy. The future mother is better used to relieve pain and treat other, less dangerous drugs. Today, the pharmaceutical market offers pregnant women a wide range of different safe homeopathic remedies that are allowed to be used when bearing the fetus.

Also, Pentalgin is not used during the baby's feeding period. Active substances that make up the drug are very quickly absorbed into the blood and enter the breast milk. For treatment with pentalgin it is better to transfer the baby to artificial feeding or refuse to take this medication.

Pentalgin for children

Pentalgin for children The drug is taken after 12 years. Before the specified age to use Pentalgin in the treatment of children can not be in accordance with the instructions of manufacturers of medication. For children from 12 years of age it is undesirable to use a single dose in the form of two tablets. Otherwise, the drug will negatively affect the child's body. Also, you should limit treatment with two or three tablets a day. The instruction allows to give children 1 tablet of Pentalgina three times a day.

If you experience weakness, nausea, allergies, vomiting, dizziness, tinnitus, and other adverse side effects, medication should be discontinued and consulted by your doctor.

After operation

The drug is a very powerful painkiller, so it is often used to eliminate various pains after surgery. Also, the drug can be effectively used after tooth extraction. It is undesirable to take two tablets once. The components of the drug are focused on rapid action, so you should wait until the pain subsides.

Pentalgin After surgery This drug is widely used during recovery from heavy surgery. You should be aware that the prescription for Pentalgin without codeine for the purchase of the drug in the pharmacy is not required. If the form of the drug does not include codeine in its composition, the medicine can be bought at pharmacies without hindrance.

The high efficacy of Pentalgine in the elimination of pain after surgery is due to the active properties of the drug components. In the body, paracetamol binds to plasma proteins and steadily blocks the development of prostaglandins. Drug substances of the drug act directly on the receptors, which cause pain.

The phenobarbital, which is part of the product, has a relaxing effect on the nervous system, soothes the nerve receptors and reduces the excitability. Complex impact of all components of Pentalgin allows quickly and persistently to remove stitching, cutting, pulling pains after surgery.

Analogues

Today the pharmaceutical market offers a wide variety of painkillers. Pentalgin has its advantages over other pain medications, but sometimes it is necessary to replace it with similar drugs. There are cheaper analogs of Pentalgin, which have a similar composition and effect. When selecting a medicinal product from a group of analogues, it is important to consult a physician in advance. Perhaps, due to the nature of the body, a similar drug will not work.

Basic analogues of Pentalgin:

  1. Pentalgin analogs Pentaflen. It is produced by the Russian pharmaceutical company. It is released by prescription. Includes narcotic analgesic.
  2. Pentamalgin. It is cheaper than Pentalgin and has similar properties and the same effect, because it contains phenobarbital and coded.
  3. Sedal M. Has the same cost as the original Pentalgin and exactly the same composition.
  4. Pliwalgin. The composition of this drug is somewhat different from the composition of Pentalgin, since it includes propylphenazone in addition to paracetamol.
  5. Sedalgin plus. The drug is Bulgarian, but less effective than the original. Does not contain spasmolytic substances.
Price

Price In the retail pharmacy network, the price of the drug may vary. Approximate cost:

  • Pentalgin( 12 pcs.) - 85-104 rubles;
  • Pentalgin( 24 pcs.) - 160 -170 rubles;
  • Pentalgin icn( 12 pcs.) - 50 rubles;
  • Pentalgin H with drotaverin - 56 -106 rubles;
  • Pentalgin H - 170 rubles.

Average price of analogues:

  • Pentamtialgin - 130 rubles;
  • Pentaflen - 70 - 100 rubles;
  • Sedal M - 120 - 230 rubles;
  • Plivaldin - 50 rubles;
  • Sedalgin plus - 126 - 260 rubles.

Feedback on the application of

Review No. 1

Pyla most recently Pentalgin after surgery on the pancreas. The medicine is very effective and quickly relieves pain. Pentalgin is used throughout my family to relieve headaches and when teeth become inflamed. A good and high-quality drug.

Irina, 45 years - Moscow

Review No. 2

I know this medicine for a long time - it quickly eliminates any pain and allows you to feel better already ten minutes after taking. Sometimes I drink it with sprains after training.

Constantine, 33 years - Novosibirsk

Review No. 3

I often use Pentalgin for headaches. Quickly removes a strong migraine. I recommend it as a good and quality analgesic.

Nikita, 62 years old - Samara

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