Hormones And Biochemistry

Antibodies to thyroid peroxidase: the norm and deviations

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In recent years, doctors often diagnose disorders in the endocrine system in women and men. For example, such a disease as an autoimmune thyroiditis is presumably detected in every 5-th person who applied to the clinic.

External symptomatology should always be carefully checked. Optimal option will be the delivery of tests on AT to TPO.To understand the result, you should know about what should be the norm in a healthy person. At the time of taking the tests, every 10th woman and every 20th man found AT to TPO, but only if their level is raised, the situation becomes dangerous.

TPO or thyroid peroxidase / thyreperoxidase is an enzyme produced by the thyroid gland that plays a role in the biosynthesis of hormones. These are complex protein compounds formed in the body, which he considers to be something foreign, along with the immune system.

At present, a considerable number of antibodies found in the human body have been identified and studied, each of which is endowed with its function. Most of these disorders occur in the body of women. Fertile soil for this is the age-related changes - the older the lady, the more the risk is increased.

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When investigating TPO

Examination

TPO is most often investigated by physicians for thyroid disorders. This is the necessary enzyme in the life of the female body, for which the immune system is responsible. But in case of failures, it is he who is susceptible to the production of antibodies - proteins, which must eliminate the negative cells that are formed. Control of antibodies to thyroid peroxidase in women and men is carried out through blood tests and competent interpretation according to the norm. TPO serves as an accelerator for the performance of hormones such as T4 and T3.

In cases when the level of AT to TPO is increased, the production of hormones is greatly reduced. Also, this enzyme plays an important role in the development of the norm of iodine in the body in a natural way. To block the growth of antibodies at an early stage, you need to be seen as often as possible in the endocrinologist, especially women.

Signs of the impact of increasing the AT to TPO

Thyroid function is important in the life of all women, the timely detection of signs will help to maintain health.

  • goiter( enlargement of the thyroid gland);
  • swelling on the legs( shin);
  • rudeness in the voice;
  • hair loss;
  • endocrine ophthalmopathy.

Consequences of increasing AT to TPO

As a consequence, there can be damage to the cardiovascular system, the musculoskeletal system. The work of the nervous and reproductive system is disrupted.

Pregnant women should take special care of themselves, because any violation can affect the baby. The most common syndrome at birth is hyperthyroidism in infants. After delivery, doctors have only 14 days to detect pathology, so children also need to take tests. Any omissions of the norm can lead not only to disruption of the endocrine system, but also to dementia.

Reasons for

Examination

The reasons for the increase in antibodies in women are still not completely revealed, but physicians assume that they are the following:

  • of the thyroid gland;
  • poor heredity;
  • toxin poisoning;
  • some chronic diseases;
  • viral infections;

Also the reason that the level of AT to thyroid peroxidase is increased, will be the bearing of the child. Related to the above is the fact that during pregnancy, women begin hormonal changes.

Immunoglobulins to thyroid peroxidase - this is the autoantibody. Their active compound occurs in the body of women in autoimmune processes( i.e. under the influence of a personal immune system) in the thyroid and leads to the development of such diseases as:

  • chronic or subacute thyroidin;
  • an increase in the organ( diffuse or nodular);
  • hypothyroidism( the process of reducing the main function of the thyroid gland);

Norm of AT to TPO

Age of the patient Norm
Up to 50 years of from 0.0 to 34.9 ed / ml.
Older than 50 years old From 1.00 to 99.9 ed / ml.

If the level of antibodies to thyroid peroxidase is increased by 20 ad / ml is the norm and does not require treatment, but mandatory monitoring and systematic observation should be provided. An increase of more than 25 ed / ml already requires medical intervention.

Treatment of

Treatment will consist of hormone therapy. Completely cure this is impossible, with the help of drugs doctors will only maintain the norm of AT to TPO.In no case should be engaged in self-medication of , the level of antibodies can be raised again, which will lead to new problems.

Prevention

  • get rid of bad habits, but it's better not to buy them at all;
  • eat right;
  • choose the most environmentally friendly area for living;
  • observe the regime of the day. This is especially important for women, sleep disturbance leads to problems with the functioning of the thyroid gland;
  • to maintain psychological health, to try to be always balanced, calm;
  • monitor the health of the internal sex organs.

In order to control the level of development of antibodies to TPO, one should not only lead a healthy lifestyle, but also be constantly observed in medical institutions. Systematic research at least once a year will help you learn about any deviations and relieve unnecessary stress.

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