Actovegin is a medicinal product that activates metabolic processes in tissues, thereby improving trophism and positively affecting the regeneration process. He is one of the most popular representatives of antihypoxants.
Antihypoxants - medical products that can improve the utilization of oxygen and glucose in the body, thereby reducing the need for it.
We will study the long-term practice of using Actovegin in tablets and ampoules - evidence-based medicine, reviews of doctors and patients, and summarize.
Contents of
- The first acquaintance of
- When is Actovegin used?
- Evidence-based medicine
- Long-term use of
- Medication during pregnancy - just the facts
- Application in childhood
- Experience with neurological diseases
- Physicians' reviews
The first acquaintance of
The composition of Actovegin includes:
- amino acids;
- low molecular weight peptides;
- antioxidant enzymes;
- intermediate products of carbohydrate and fat metabolism;
- nucleosides;
- electrolytes and microelements.
Each component has its own function:
- Amino acids are the most real building material for protein molecules. This is of great importance, since it is the protein that plays a major role in the regeneration of tissues.
- The low molecular weight peptides at first glance are not much different from high molecular weight peptides( both are proteins), but with detailed consideration of the characteristics it can be seen that in high molecular weight the risk of causing an allergic reaction is slightly higher than that of others, therefore the use of low molecular weight peptides in Atoweginis justified.
- Antioxidant enzymes at this time accelerate the formation of oxygen in cells, but at the same time block the destructive effect of free radicals.
- The role of amino acids and proteins is understandable, but how are they synthesized? This process is due to the presence of intermediate products of the metabolism of carbohydrates and fat in the drug , which are the basis for this synthesis.
- It is also very important to form a genetic component of newly formed cells. The nucleosides are responsible for this in the preparation.
- Electrolytes and microelements , being obligatory components of blood plasma, influence the best absorption by the body of the drug.
When is Actovegin used?
There are a number of indications in which people are prescribed treatment with this drug.
It is prescribed for metabolic and vascular disorders in the brain, taking into account even craniocerebral trauma. Also, Actovegin will be appropriate for vascular disorders of various types and their consequences. Vascular disorders can be both arterial and venous - this drug will cope with both types.
The drug also helps with chemical and thermal burns, as its main advantage is the acceleration of tissue regeneration. For the same reason, this drug will be ideal for the healing of small wounds or abrasions, the elimination of decubitus. 
It would seem that Actovegin is an ideal means to quickly remove undesirable damage to the skin and mucous membranes, but even here there is a danger. Never take this medication yourself, because even the most harmless remedy has a number of contraindications.
This medication should not be used in people with heart failure of the first or second degree, diabetes mellitus, hyperhydration, pulmonary edema, anuria, oliguria, hyperglycemia, and pregnant women or women during lactation.
The rest can use Actovegin, but even in the absence of the aforementioned diseases there is always a risk of an allergic reaction with individual sensitivity to the drug or the like. Allergies to this remedy may manifest in the form of urticaria, swelling, or drug fever.
Evidence Based Medicine
Above, most of the contraindications to the use of Actovegin have been listed. But even if all the rules are followed, there is never a guarantee that an unfamiliar drug prescribed by a doctor will help improve the overall condition of the patient without harming him. In order to avoid such problems, there is evidence-based medicine.
Speaking specifically about a drug such as Actovegin, the history of medicine has several studies that prove its effectiveness.
According to them it follows that in our time there are two large groups of patients for whom treatment with Actovegin is the most productive. These are either people with chronic cerebrovascular pathology, or patients with complications of diabetes mellitus.
Cerebrovascular pathology is a group of circulatory disorders in the brain area. Among these pathologies, transient disorders of cerebral circulation and strokes are distinguished. For these diseases are characterized by: headache, noise and ringing in the head, puffiness and cyanosis of the limbs, rolling numbness.
There have also been good results in the treatment of cognitive diseases, which are typically characterized by a decrease in memory function and a decrease in mental performance compared to its baseline level.
More than 400 people took part in the research of therapeutic properties of Actovegin. One group was given a drug, and the second - the usual candy, stylized for tablets( the so-called "placebo").
In the group that was taking Actovegin, significant positive results were noticeable already at the fourth week of taking the drug. If we talk about percentages, in the Aktovegin group 70% of patients marked a definite improvement, while in the "placebo" group only 30% were noted.
An approximately identical study was conducted by other scientists, but this time Actovegin was used as a medicine against Alzheimer's disease and multi-infarct dementia.
Multi-infarct dementia, this is when as a result of several strokes, certain cognitive impairments are formed, the totality of which is called this name.
As with the treatment of cognitive diseases, the percentage of positive action of Actovegin on the body was much higher than the effect of "placebo".As a result, it can be concluded that this drug gives a positive result not only during the treatment of external injuries, but also helps with neurological disorders and cognitive impairment for one reason or another.
Long-term use of
In the sheet-characteristics, which can be found in virtually any medicine box, all possible information on dosage, 
contraindications and storage method is given.
But even with an exhaustive completeness of facts, I want to hear people's testimonials. But, alas, they can not all be equalized as one comb, as the use of Actovegin, both in injections and in tablets, can have nuances depending on the disease, therefore, it is better to consider the responses in groups.
In the instructions to Actovegin you can notice an interesting and important line in which you are warned about possible complications when taking the medication during pregnancy. This nuance should be considered in more detail.
Taking medication during pregnancy - only facts
Actovegin has a natural composition, therefore it can not in any way negatively affect the fetus. The risk exists only if the kidneys of a pregnant woman were susceptible to disease even before pregnancy.
Kidneys remove toxins from the body, which in small quantities appear during medical treatment. This does not harm a healthy body with balanced kidney function, however pregnant women are a completely different case, since their natural filters during the bearing of the child are subjected to a double load. Nevertheless, despite this, doctors still prescribe Actovegin to pregnant women.
Further reviews of women who took Actovegin during pregnancy.
I was going through the seventh and a half month of pregnancy, when ultrasound revealed in my body a low oxygen content( or hypoxia, if scientifically).
We put it in the day hospital, where we started placing drippers with Actovegin in a solution of glucose. At first they wanted to prick pricks, but I refused, because I'm afraid of them. After 10 droppers again went to the ultrasound, and everything was in perfect order - hypoxia completely disappeared.
I had some more water, which did not disappear, but it became moderate.10 capsules of medicine cost 900 rubles. And the daughter, by the way, was born healthy and with normal parameters.
Natalia from the city of Orel
Christina from Moscow had a more serious situation:
The whole pregnancy went well, but suddenly at the sixth week there was a threat of interruption with bleeding. Fortunately, everything worked out, but because of the sudden appearance of a strong toxicosis, I threw off weight from 50 kg to 43.
Doctors waved their hands - no one knew what it was for, but as a result, fears about the baby began to creep in again. For prevention, a course of 10 IV injections was prescribed. The treatment helped, and by the 30th week my weight was normal.
According to the weight of the baby, of course. Until now, we can not understand what it was, but my husband and I are sure that it was because of the course of the drug that the son was born healthy.
Cristina, Moscow
This drug not only serves as a panacea for the treatment of the developed disease, but also improves the general condition of the body. This effect on myself was checked by Evgenia Smirnova from Ufa:
I was always painful in life, but I want a baby. As a result, the whole pregnancy passed with a terrible toxemia, anemia and poor blood circulation until the moment when I was not assigned Actovegin.
At first it only got worse, but, as I later learned, I was pricked by a Belarusian analogue, then I started using a normal drug. After that, the state of health improved significantly, the birth was successful and the child was born healthy!
Evgenia Smirnova, Ufa
Application in childhood
Another controversial issue is the appointment of Actovegin to children, parents' opinions on this matter are also ambiguous. Nastya from Ekaterinburg also finds it difficult to answer:
After her hypoxia, her son was found with a cyst, but she somehow disappeared by herself when he was four months old, because the doctors did not prescribe anything. At daughter's daughter the diagnosis was repeated, but she was prescribed Actovegin. The cyst was gone by six months.
I liked very much that before the course of treatment she was given a test shot so that there was no allergy.
Nastia from Ekaterinburg
Actovegin is a drug that is preferably used for the treatment of neurological diseases. Irina from Syzran saw the result on her son:
We had some backwardness in development, as a result, in the complex of other tablets, we were prescribed another Actovegin. The injections are painful, the cry was every day, but there's nothing to be done. But what a result.
Son, so calmed down, became cheerful and animated, reacted to our words and requests. True, I did a lot with him. In general, advice to all mothers - medication is good, but do not rely solely on tablets and pay attention to your child.
Irina from Syzran
Experience with neurological diseases
Since we are talking about neurological diseases, it's time to look at the responses of other people who fought them with Aktovegin.
Semyon from St. Petersburg says:
I suffered for a long time because of headaches, I thought it was not working, because the work is heavy. As a result, I could not stand it, I left, but my headaches did not stop. I went to the hospital. I do not remember the exact diagnosis, but something with the blood vessels. They prescribed Actovegin, and I was very surprised that it helps, since the drug, in fact, should improve the activity of the brain. The only negative is the price. For 5 ampoules paid 500 rubles.
Semen from Petersburg
Based on the reviews, one can come to the conclusion that Actovegin is a universal drug that can be assigned to both a baby and an elderly person. Unfortunately, the results of treatment are individual, because it is impossible to predict in advance how strong will be the improvement of well-being after the application of this medication.
Doctors' reviews
Actovegin can be used both for the treatment of external wounds and abrasions, and for the elimination of cognitive disorders, we will study current reviews of doctors about the drug.
Pharmacist Uchelkina LA believes that this medicine is best suited for the treatment of skin lesions.
With inflammatory wounds and ulcers I recommend only Actovegin. Gel 20% concentration helps to clean the wound, after which you can safely continue treatment with 5% cream. Basically, the cream is used to complete the treatment, since it promotes tissue epithelialization.
Also one of the main advantages of the drug is that it can be used for a long time without the risk of allergies.
Uchelkina L. A
Elena A., neurologist, only recently got acquainted with the results of studies of evidence-based medicine:
I read articles in the library of evidence-based medicine and I was glad that Actovegin was finally recognized as an active drug. Too many patients refused treatment because of rumors that revolve around this remedy.
Recommendations of doctors they stubbornly ignored, although in Russia the majority of doctors believe in its effectiveness.
Elena A.
Also Actovegin medicine is actively used in the field of cosmetology.
Olga Dmitrievna, cosmetologist by profession, shares her opinion with us about this drug:
Actovegin in the form of ointment is often used to cure the problem skin( pimples, acne, and so on).True, you need to be careful and conduct tests for an allergic reaction, otherwise it can only become worse. This can be avoided by consulting a doctor.
It is in our best interests to give full information about the drug in order to improve the patient's health. Do not believe the experts on the Internet, because reviews - this is primarily a subjective and individual opinion. It's not a fact that if it suits someone, it will suit you.
Olga Dmitrievna
If you take into account the opinions of doctors and patients, you can conclude that the average result of treatment with Actovegin is positive.
However, it is worth remembering that the result is always individual and depends on many factors, therefore, before using the medication, consult with a specialist who prescribes a certain form of the drug and a dosage that is suitable for you, which will not cause an allergic reaction.
