Before drinking Stugeron: the instructions and reviews of those who took the drug

Contents

Pharmacological action of

The active ingredient of the drug is cinnarizine. It has a blocking effect on the calcium channels, thereby reducing the flow of calcium into the cell. This leads to a decrease in the tone of the walls of the blood vessels, which in turn ensures their relaxation and increased lumen of the vessels. Thus, blood circulation in the tissues improves, as well as their nutrition and oxygen saturation.

The most pronounced effect of Stegeron is manifested on the vessels of the brain and peripheral tissues. This reduces intracranial pressure and improves blood microcirculation.

Pharmacokinetics

After oral administration, the drug is absorbed within an hour. However, its bioavailability directly depends on the content of hydrochloric acid in the stomach.

The maximum concentration in the blood is noted 1-3 hours after the application, and the half-life of the drug is 4 hours.

Metabolic processes occur in the liver by glucuronation. The products of the metabolism of the drug substance are excreted from the body by 1/3 of the kidneys and 2/3 of the intestines.

Composition of the preparation and form of release

Stugeron is manufactured by Gedeon Richter in the form of tablets for internal administration.

Cinnarizine formula

Each tablet contains 25 mg of cinnarizine active substance. In addition to it, the formulation also includes auxiliary substances that are needed to fill the dosage form, to prevent clumping of the tablet mass during production, and to ensure the rapid disintegration of tablets into the gastrointestinal tract and the absorption of the active substance into the blood.

The preparation contains the following auxiliary components: potato starch, talc, colloidal silicon dioxide, magnesium stearate, lactose monohydrate, polyvidone.

To whom for good, and to whom and to the detriment of

Stugeron tablets have the following indications for use:

• for maintenance therapy for all possible disorders of the cerebral circulation of the brain ( eg, due to craniocerebral injury, vascular spasm, disk encephalopathy, etc.);
• therapy of chronic circulatory insufficiency of the brain , which is accompanied by memory disorders, migraine, fatigue, tinnitus, dizziness, irritability;
• for the treatment of symptoms of labyrinthine disorders of : nausea, dizziness, vomiting, tinnitus, nystagmus;
• kinetosis ;
• for the treatment of diseases and conditions associated with peripheral circulation pathologies : intermittent claudication, sensation of cold and numbness of the extremities, syndrome and Raynaud's disease, trophic ulcers, pressure ulcers, trophic disorders, Burger's disease, varicose ulcers, acrocyanosis, trophic tissue disorders in diabetes,leg cramps at night, obliterating atherosclerosis.

Like any pharmaceutical product, Stugeron has its own contra-indications and warnings for use. This:

• excessive sensitivity to any component of the drug;
• periods of pregnancy and lactation.

How to apply the drug: tactics and strategy

Stugeron's reception is somewhat different for various diseases, of course, the dose and schedule of the appointment should be prescribed by the doctor in each case individually, but that's what the instructions to the drug say:

• for diseases related to circulatory disordersBrain take 1 tablet 3 times a day;
• for labyrinthine disorders appoint 1 tablet of Stugeron 3 times a day;
• for abnormalities related to peripheral circulation disorders , 2-3 tablets( 50-75 mg) 3 times a day should be taken;
• with kinetosis ( motion sickness in transport) take 1 tablet 30 minutes before departure and then repeat the reception every 6 hours.

This dosage is calculated for children over 12 years and adults. The maximum allowable daily dose for this category of patients is 225 mg( 9 tablets).

If you need to take the drug in young children( from 6 to 11 years), then the dose should be reduced by half. The possibility of using the drug in early childhood should be decided together with the attending physician.

Tablets should be taken after meals, with plenty of clean water.

The course of treatment for this drug is assigned in each case individually and depends on the severity of the disease, as well as the rate of manifestation of positive changes in the patient's condition. The average course of therapy with the drug lasts 3 months. In some conditions and illnesses, it is necessary to conduct several courses of therapy a year, with interruptions between them for at least 1 month.

Alcohol intake during Stugeron therapy is prohibited.

In case of impaired liver and kidney function, the drug should be administered with caution and under constant medical supervision.

Cases of overdose

In cases of drug use in doses exceeding the maximum allowable( 225 mg per day), an overdose is possible, which is expressed by the following symptoms:

• drowsiness;
• excessive lowering of blood pressure;
• vomiting;
• tremor;
• coma.

There is no specific antidote for treating this condition. It is necessary to wash the stomach and take an absorbent preparation( activated charcoal, Atoxil, Enterosgel, etc.).

Side effects of

Stegeron tablets may cause a variety of undesirable side effects:

• from the digestive tract : dry mouth, dyspepsia, epigastric pain, bile duct failure;
• from CNS : increased fatigue, drowsiness, depression, frequent headaches;
• allergic reactions of in the form of rash, hives, etc.;
• from the skin : lupus erythematosus, lichen planus;
• other side effects of : weight gain, increased sweating.

Drug interaction

Stugeron is not recommended to be used concomitantly with drugs that depress the central nervous system( sedatives, tricyclic antidepressants, hypnotics, etc.), since it is possible to enhance the sedative effects of these drugs.

When applied simultaneously with antihypertensive, nootropic agents and vasodilators, the therapeutic effects of medicines are mutually reinforced.

It is important to consider that Stugeron reduces the severity of the action of drugs that increase blood pressure, such as, for example, Caffeine, Mezaton, Cordiamin.

With simultaneous administration with phenylpropanolamine, the intensity of the therapeutic effect of the drug decreases.

Use during pregnancy and lactation

It is forbidden to take the drug during pregnancy and lactation, as there have been no studies to identify the absence of adverse effects on the fetus or the baby.

Features of the application in childhood

Infants and young children often have diseases of the nervous system that require treatment, quite often in such cases Stugeron is appointed, despite the age restrictions specified in the annotation. It is rather well tolerated by small patients and gives excellent results of treatment.

The dose of the drug for small children is calculated in each individual case, taking into account the age, weight of the child, his general condition, the degree of neurologic changes, etc. At the age of up to 6 months, the daily dose of the drug should not exceed ½ tablets.

More senior children a daily dose can bring up to 1-2 tablets. The most frequent course of treatment is 1 month. After carrying out repeated studies, it can be continued for a longer time.

Before use, the tablet or part of it should be thoroughly crushed and dissolved in 2 teaspoons of water.

Stugeron is actively used in children's practice because of the lack of drugs with a similar effect, designed to treat children.

How things stand in practice

The network has numerous positive testimonials about Stugerone, both doctors and those who took the drug, which indicate a high effectiveness of the drug. Below are a few of them.

What Do the Doctors Say?

What do patients say?

Advice on receiving from reviews

Before using, consult a doctor and read the instructions for use carefully.

Stugeron should be taken only after a meal, as it causes irritation to the stomach. To avoid dry mouth, you should drink more liquid during therapy.

Advantages and disadvantages of

Advantages:

• high efficiency;
• possibility of reception by different age groups of patients.

Disadvantages:

• is a more expensive price compared to Cinnarizine;
• in case of an overdose, it is possible to develop serious side effects, up to coma.

At the

pharmacy The average price of Stugeron's pack containing 50 tablets varies between 157 and 190 rubles, which makes this drug affordable for the general population.

Cinnarizine possesses a similar composition with Stugeron.

What is better than Stugeron or Cinnarizine?

Cinnarizine is a complete analogue of Stugeron. Therefore, an unambiguous answer, which of the two preparations is preferable rather difficult. They are interchangeable. So what's the difference? Stugeron is a patented name. This drug is produced only by one manufacturer - Gideon Richter, therefore its composition, including auxiliary substances, is always the same.

Under the name of Cinnarizine, the drug produces many pharmaceutical companies. Such drugs may differ in the amount of active substance and the composition of additional components, which can affect the rate of absorption of the drug in the blood and the severity of its action.