Tablets and ampoules Kenalog - instructions for use, conflicting reviews and analogues

Kenalog is a drug for systemic use and refers to the pharmacological group of glucocorticosteroids.

In its composition Kenalog contains one active ingredient - triamcinolone, which has anti-allergic, anti-inflammatory and immunosuppressive medicinal effect.

Practical comparison of Kenalog with other glucocorticosteroids showed that this preparation is safer than its analogues: it does not violate the normal removal of fluid from the body, does not adversely affect the water-salt balance, its diabetic effect is negligible.

In addition, the instructions for use indicate that Kenalog least of all has a depressing effect of on pituitary function.

Pharmacokinetics of the drug

Depending on the dosage form of the drug, its maximum effectiveness in the body is achieved in 8-12 hours( tablets) or 24-48 hours( suspension for injection).

The drug is metabolized in the liver. It is excreted from the body with urine.

Indications for use

Kenalog is prescribed for both local and systemic use, depending on the patient's condition and the desired effect.

For systemic use the drug is prescribed in such cases:

• obstructive chronic diseases of the respiratory system( bronchitis, asthma);
• hay fever;
• skin diseases( some types of dermatitis, accompanied by peeling, blistering, wounds, itching, psoriasis, pemphigoid).

For topical use, the drug is prescribed in such cases:

• joint disease( arthritis, gout, arthrosis, blockade of the shoulder joint, dropsy joints, and others);
• cystic formation;
• inflammation in the periosteum;
• bursitis;
• chronic lupus erythematosus;
• isolated skin diseases( flat nodular lesions, isolated plaques of psoriasis);
• hair loss in the form of a circle.

Contraindications for the use of the Kenalogian

The instructions for use also indicate that the Canal has many contraindications.

This medication is not prescribed if the patient has such diseases:

• gastrointestinal ulcer;
• mental disorders;
• bone atrophy in severe form;
• viral diseases( shingles, chicken pox, herpetic pemphigus);
• infectious diseases of internal organs caused by fungi;
• poliomyelitis( in childhood);
• glaucoma.

Also Kenalog is contraindicated in case of patient's individual intolerance to the components of the drug.

In addition, the drug may be contraindicated before vaccination( 8 weeks) and after this procedure( within 2 weeks).

As a rule, Kenalog is not administered intramuscularly to children under 12 years of age.

Local treatment with is contraindicated in for skin diseases caused by bacteria, as well as skin lesions of syphilitic or tuberculous nature.

With caution, the drug should be used with with:

• muscle disease in severe form;
• susceptibility to thrombosis;
• progressive metastasis formation;
• diabetes mellitus;
• of previous ulcerative diseases;
• epilepsy;
• heart failure;
• disorders of the liver and kidneys.

Mechanism of action of the preparation

As mentioned above, the Kenalog has an anti-allergic, anti-inflammatory and immunosuppressive effect.

This effect is achieved due to the fact that triamcinolone entering the body reduces the level of certain enzymes in the inflammatory focus, thereby stopping the inflammatory process.

In addition, the active component limits the movement of leukocytes, suppresses the formation of antibodies, stabilizes the number of lymphocytes and reduces the permeability of capillaries.

In addition, the drug at the time oppresses the function of the adrenal glands. Due to its rapid absorption, positive dynamics can be traced quite quickly.

Method of administration of the Kenalog and dosage of

The procedure for the use of this drug is determined exclusively by the doctor after assessing the patient's condition.

The patient is not recommended to make independent adjustments to the course of treatment, because this can have negative consequences.

Use of medication in tablets

Depending on the dosage, the drug can be taken in one session( preferably in the morning) or several( if the daily dose exceeds 16 mg).

Instructions for use on tablets Kenalog 40 indicates that for adults the average dosage of the drug is from 4 to 32 mg per day , but depending on the patient's health, the presence of concomitant diseases can be increased to 75 mg.

For children, the dosage is calculated based on weight, 0.5 mg per kg body weight, but the maximum dose is 14 mg.

To cancel treatment, the dosage of the drug should decrease gradually, 1-2 mg every 3 days.

Injection suspension for injection

When intramuscular injection, 40 mg of the drug( 1 ml) of is usually used, only in rare cases the dose is 80 mg. Between injections, there must necessarily be a break of 2 to 4 weeks.

For the treatment of allergies, the drug is used at a dosage of 40 mg once a year before the onset of the allergy season.

The dosage for children is calculated according to the patient's body weight, a maximum of 0.2 mg per kilogram.

For intraarticular administration, the dosage is 10-40 mg for one joint, but not more than 80 mg for all joints per injection. The interval between the administration of the suspension should be 20-30 days.

Overdose

When taking Kenalog, a one-time and chronic overdose is possible.

Symptoms of one-time are nausea, vomiting, increased excitability, a sense of euphoria. Chronic overdose, which occurs with prolonged use of high doses of the drug, is characterized by weakness in the muscles, fluid retention in the body. In addition, the function of the adrenal glands is greatly inhibited.

In case of overdose, consult a doctor who prescribes treatment according to symptoms. It is important to know that you can not stop taking the drug abruptly, even in case of an overdose. The dose should decrease gradually.

Side effect of Kenalog

It should be noted such:

1. Heart and circulatory system: heart rhythm disturbances, increased activity of the thrombus formation process and, as a result, the hanging of blood clotting, arterial hypertension.
2. Central Nervous System: sleep disorders, headaches, dizziness. Possible development of depressive, obtrusive, anxious, paranoid conditions. Also, the patient may have a tremor of extremities, convulsions, increase intracranial pressure.
3. Musculoskeletal: Osteoporosis, weakness or atrophy of some muscles, bone loss. In children, growth is impaired.
4. Skin covers : the appearance of acne, pigmentation spots, stretch marks. When injecting the drug, scar formation and partial numbness of the skin are possible.
5. Gastrointestinal tract: in the process of treatment Kenalogom possible eating disorders, nausea, vomiting, anorexia, ulcers.
6. Endocrine system: increased patient weight, increased sensitivity to glucose, inhibition of adrenal hormone production.
7. Exchange processes: decrease in potassium and calcium levels and increase in the amount of sodium in the blood.
8. Vision: cataract, increased intraocular pressure, corneal changes.
9. Also, the drug can cause allergic reactions ( itching, redness). When injected, a burning sensation is possible.

Special instructions for use and precautions

It is not recommended to use the drug in the first 5 months of pregnancy, becauseTriamcinolone can cause fetal development abnormalities. Also it is not recommended to use this remedy in the last month of pregnancy, because it can damage the functioning of the adrenal glands and the child.

In any case, the use of the drug during pregnancy should be under the supervision of a doctor.

During breastfeeding, the drug can be used if the patient is given small doses of Kenalog and the course of treatment is not long.

Diet in treatment with Kenalog

During the period of treatment, the patient is recommended to consume more protein foods and vitamins.

If the patient has an infectious disease, Kenalog treatment is possible only with the simultaneous use of antimicrobials.

It is recommended to control the blood sugar level, because the Kenalog can increase the level of glucose.

During the period of treatment, the patient is advised to stop driving the vehicle and engage in activities requiring increased attention, concentration and mental activity due to possible side effects.

You should also refrain from drinking alcohol.

The drug is dispensed by prescription.

Interaction with other

medications Before using Kenalog at the same time as other medications, please check with your doctor if this is possible and what effect the combination gives:

• For example, Kenalog weakens the effect of an anticoagulant. A phenytoite and barbiturates, in turn, reduce the effectiveness of the Kenalog.
• With the combination of Kenalog with drugs that have a diuretic effect, an increased amount of potassium is excreted from the body.
• Anti-inflammatory drugs from the non-steroid group in combination with Kenalog increase the risk of disorders in the work of the gastrointestinal tract.

Terms and Conditions of storage

Do not use the product after storage for more than 3 years( for suspension) or more than 5 years( for tablets).

It is recommended to store in a warm( up to 25 degrees), dark and dry place. Hide from children.

Form and Cost

Issue in as:

• tablets( 4 mg of active substance per tablet);
• suspension for injection( 40 mg triamcinolone per 1 ml).

Price:

• price of ampoules Kenalog( 5 ampoules) - 300-480 r;
• price of pills Kenalog 40: 180-250 p.

Reviews of doctors and patients about Kenalog

Judging by the feedback on the use of Kenalog, , many patients were afraid to start treatment with this drug, because they were frightened by rumors about its toxicity and an impressive list of side effects.

However, when other funds did not help, I still had to resort to the Kenalog. Most of those who used the drug for the treatment of joint diseases, note its effectiveness .

The pain decreases significantly after the first injection, the effect is quite long. And some patients claim that Kenalog was much more effective for them than expensive analogues.

Also is effective preparation with frequent lesions of eyelids with barley, haljazionom. However, it should be noted that side effects still make themselves felt. Many patients deteriorate skin condition, body weight increases. Women have malfunctions of the menstrual cycle.

The inefficiency of Kenalog is noted as a cure for alopecia and with seasonal fevers. However, each organism is individual, so before choosing any medication for itself, you should consult your doctor.

Advantages of Kenalog:

• is relatively inexpensive;
• positive result is noticeable almost immediately;
• is effective in joint diseases;
• gives good results in the treatment of skin diseases.

Disadvantages of Kenalog:

• high enough toxicity of the drug;
• serious side effects;
• is not always effective in seasonal allergies;
• can not be stopped abruptly if it is ineffective or intolerant.

Analogues of the drug

Consider the main analogues of Kenalog.

Polcortolone

This formulation contains the same active ingredient as Kenalog, and the amount of triamcinolone is similar to that of Kenalog( 4 mg in 1 tablet).Pollortolone is available only in the form of tablets.

Has more pronounced anti-inflammatory effect of , aimed at treating a wider range of diseases.

Features of application, contraindications and side effects are similar to Kenalog.

Price: 200-430 р.

Focort

Available as an ointment for external use. Active substance - triamcinolone( 1 mg per 1 g of cream). Indicated for the treatment of skin diseases( dermatitis, psoriasis, eczema), alopecia, insect bites.

The pluses can include a softer impact on the body, a small list of side effects, no risk of overdose.

Price: from 120 p.

Fluorocord

Also available as an ointment. The active component is the same. Indications for use of : dermatitis, eczema, psoriasis, lichen, otitis media of the external ear, lupus erythematosus.

Unlike Focort, this drug has side effects similar to Kenalog. There is a risk of overdose.

Children are appointed only in exceptional cases.

Deprecated by prescription.

Price: 130-210 р.