Application of the Relum in Neurological Practice: Instruction and Feedback

Relium, the international name Diazepam, is a common sedative. Effective in the fight against convulsive syndromes, struggling with insomnia.

Relaxes muscles after exercise, relieves nervous tension, anxiety and other nervous disorders. However, the drug can cause addiction.

Ingredients

For sale Relium as a solution and coated tablets. Relate to the group of benzodiazepines. Widely used in traditional medicine for the treatment of neurological diseases.

In one package, 20 tablets of 5 mg each. In addition to the main active ingredient of diazepam, the composition of the drug includes: gelatin, potato starch, talcum, tween 80, lactose, magnesium stearate.

There are packages with 24 tablets of 5 or 10 mg each. Also available in the form of a solution for intramuscular and intravenous administration of 10 mg each ampoule.

Diazepam formula

Pharmacological action

The drug has an anxiolytic, sedative, hypnotic, anti-seizure and muscle relaxant effect on the body.

All these effects are due to the unique chemical composition of the product. Benzodiazepines, which are part of the chemical composition of the drug, have a positive effect on the central nervous system, so that various nervous disorders can be effectively treated.

The anxiolytic effect is due to the effect of the drug on the limbic system of the brain. As a result, the patient gets rid of a spontaneous feeling of fear, anxiety, excessive anxiety. Emotional tension is removed.

The Relium also affects the reticular formation of the brain. This structure carries out activation of the cerebral cortex and controls the reflex function of the spinal cord. Therefore, when using drugs, neurotic sensations, such as fears and anxiety, are reduced. This is the sedative effect of the drug.

Anticonvulsant effect manifests itself in the form of warning of another epileptic fit. Although the next attack can be suppressed with the drug, the epilepsy focus in the brain remains in an excited state.

The miorelaksiruyuschee effect on the body due to the effects of drugs on neurons and axons of the spinal cord. In this case, the braking of the spinal cord occurs, as a result, braking of muscles and motor nerves occurs.

The Relium can lower arterial pressure, expand coronary vessels, increase sensitivity to pain, decrease secretion of gastric juice and suppress vestibular paroxysms.

The effect can be felt on the 7th day of treatment. But the drug does not affect the appearance of acute delusional, hallucinatory, affective disorders.

The use of Relium weakens the feeling of agitation, delirium, tremor and negativism.

In people with cardialgia, arrhythmia, paresthesia, by the end of the first week there can be a positive therapeutic effect from taking the medication.

Pharmacokinetic properties of

After use, the main active ingredient in the preparation of diazepam rapidly dissolves in the digestive tract and is absorbed into the body.

It quickly reacts chemically with blood proteins and spreads throughout the body. It is deposited in adipose tissue, then gradually released and enters back into the blood.

The elimination period is from 24 to 48 hours. The process of excretion may be longer in infants and elderly people. It is excreted together with urine in the form of metabolites. Regular use can ensure the accumulation of metabolites in the body.

Scope of Application

Relium is recommended for those who suffer from insomnia. Regular use will facilitate the process of falling asleep.

And also to those people who have:

• muscle spasms;
• dysphoria( low mood);
• cerebral palsy, tetanus, athetosis and other conditions associated with brain trauma;
• angina, severe head pain, vertebral syndrome;
• alcohol syndrome: agitation, tremor, anxiety, etc.;
• epilepsy, arterial hypertension, psychosomatic disorders, eczema, gestosis, stomach ulcers and 12-colon, irritability, myocardial infarction, etc.(as part of complex therapy);
• , premature birth and premature detachment of the placenta, etc.

Dose regimen and prescribed dosages

Depending on the type of disease, the patient's state of health, the sensitivity to the drug, the prescriber appoints and selects the dosage.

The reuIium is ingested orally, administered intravenously or intramuscularly, the instructions show the following dosages depending on the purpose of the drug:

1. The recommended dose of for neurological and psychiatric disorders ( neurosis, hysteria and hypochondria, state of dysphoria, phobias): 5 -10 mg two to three times a day. The dose can be increased to 60 mg per day.
2. Syndromes of alcoholic withdrawal syndrome : 10 mg per day for 3 to 4 times for the first 24 hours. Further, the dose is reduced to 5 mg.
3. Arterial hypertension : 2 - 5 mg per day for 2 - 3 times.
4. Initial dose of for myocardial infarction in bed rest mode: intramuscularly 10 mg. Then it is taken orally 5 to 10 mg per day 1 to 3 times.
5. With epileptic seizures of : children from 1 month to 5 years are slowly injected intravenously by 0.2 mg every 5 minutes until reaching 5 mg. Children older than 5 years - 1 mg every 5 minutes to achieve a dose of 10 mg.
6. Tetanus and muscle relaxation : children from 1 month to 5 years - intravenously and intramuscularly 1 - 2 mg. Children older than 5 years - 5 - 10 mg.
   For the elderly, the dose should be half that of young people, which gradually increases over time.

Overdose and side effect of

Drug intake above the recommended dose of a previously prescribed time is not desirable. Otherwise, side effects may occur.

During treatment with this medication, one should be extremely cautious in performing actions and work that require increased concentration of attention and motor speed. Among others, driving a car.

Like any other medicine of this group, the Relum is able to cause side effects that occur, mainly at the beginning of the course of treatment. Among other things, there may be:

• drowsiness;
• dizziness;
• constant fatigue;
• fast fatigue;
• the retardation;
• poor coordination of motion;
• lethargy;
• general weakness;
• depression;
• hallucinations;
• suicidal condition( rare);
• confusion;
• blunting of emotions, etc.

Alcohol and Relanium - what, how and why?

Different medications interact differently with alcohol. Alcohol contained in the composition of alcoholic beverages can improve, minimize, and sometimes even distort the effect of taking medications.

Many patients wonder whether it is possible to use Relium with alcohol? Champagne and similar drinks strengthen the effect of the drug on the body. However, after drinking alcohol, the patient develops a physical and mental dependence on the given drug.

But on the other hand, if diazepam is used by people with alcohol dependence, then it can dull feelings such as nervousness, anxiety, anxiety, fear, tremor, etc.

Special patients, special instructions

The Relium for patients with impaired renal and hepatic function is not contraindicated. But the dose for them should be reduced. The attending doctor, depending on the condition of the patient and the severity of the kidney and liver, individually assigns the right dose.

If you use the drug with drugs of neuroleptic, sedative, opioid effect, as well as with hypnotics, anesthesia, then there may be a negative effect: arterial hypotension, depressing effect on the nervous and respiratory system. Therefore, the use of the drug with other types of medications is decided by the attending physician.

In the first trimester of pregnancy, the use of Relium should be stopped. Otherwise, the drug may affect the development of the fetus in the womb. You can use it in case of emergency, only by appointment of a specialist. During lactation, breastfeeding of the baby should also be discontinued.

From the practice of

The network has real feedback about the Relium, both from patients and from doctors. Basically they are positive.

Terms of purchase and storage

Depending on the city and the pharmacy, the cost of the facility varies. But the average price of the Relium is about 32 rubles.

The drug is stored in a dry place, protected from light and sun. Storage temperature - no more than +25 degrees. Keep away from small children.

Available by prescription.

Analogue of the Russian-made Relium - Sibazon. There are also foreign analogues: Seduxen( Hungary), Apaureen( Slovenia), Relanium and Reladorm( Poland).