Mexidol, a broad-based drug, is an instruction for the use of tablets and ampoules, rave reviews of patients and doctors

A drug that has antioxidant properties. is prescribed with difficulty in supplying blood to the brain and its circulation , with nervous disorders.

Excellent fights with spasms, improves brain activity.

There are in the form of tablets and solutions in ampoules. Has a wide range of effects, with a small number of side effects.

Pharmacological action

Mexidol, interacting with the body, exhibits properties that are not directed against free radicals.

He has a vast field of action. This drug is prescribed in cases of poor oxygen supply to tissues, or in cases of violation of this process.

This drug lowers 's susceptibility to oxygen-dependent pathological conditions, improves memory, capacity for work and concentration, reduces the harmful effects of alcohol on the body.

What happens after the drug has entered the body

As a result of the transfer of Mexidol directly to the muscle, it is possible to detect it in the blood after 4 hours.

The upper threshold of concentration of Mexidol at the time of its entry into human tissues in the amount of 400-500 mg varies in the range of 3.5-4.0 μg / ml. To achieve this, you need 30 minutes.

After it enters the blood plasma, it quickly enters the tissues and organs, then leaves it with urine after it has been 4 hours since taking the drug.

Indications and contraindications for use

Instructions for use for the drug Mexidol says that the indications for use are much greater than contraindications.

Indications for use

Among the main:

• a sharp deviation from the normal activity of the brain;
• result of ischemic stroke;
• results of head injuries;
• in cases of vegetative vascular dystonia;
• disorders associated with neurotic and neurotic-like conditions;
• occurrence of purulent and inflammatory processes.

Contraindications

Number of contraindications much less:

• too strong susceptibility of the person to the drug;
• dramatic change in the poor performance of the kidneys;
• dramatic change in the worse performance of the liver;
• is contraindicated in children.

Mechanism of action of medicament

Mexidol is a preparation, exhibiting antioxidant properties of .

Tablets and injections Mexidol, as indicated by the instructions for use, help inhibit free radical processes, lipid peroxidation.

With its help activates the antioxidant enzyme of superoxide dismutase .It has a positive effect on the physico-chemical properties of the biomembrane.

In the process of its effect on the human body, this drug acts as a substance that protects membranes, prevents the occurrence of seizures, increases the body's resistance to negative factors and prevents the development of oxygen-dependent pathological conditions.

Mexidol improves the course of processes in the brain of , improves blood circulation and reduces the ability of platelets to be attracted to each other. It helps reduce cholesterol.

Under the influence of this drug slows down the process of lipid peroxidation, increases superoxide dismutase activity, reduces the viscosity of the membrane and, in turn, reduces its fluidity.

Due to its mechanisms of action, it has a small number of contraindications to and has a low level of toxicity.

Instructions for use

Instructions for use on Mexidol tablets and the more so the preparation that is administered intramuscularly must be studied.

Methods of application of

There are several options for the supply of Mexidol in the human tissue:

• directly to the muscle or vein;
• inkjet or drip image.

Injection nozzle is used when the number of adrenal hormones in the blood plasma increases rapidly.

The drip feed is used when there is a disruption of blood circulation in the brain. When applying Mexidol directly to the vein as a dissolving substance use special water for injection.

Injection Meksidol is given in the body for 5-7 minutes, with droplet - at a speed of 40-60 drops / minute.

Dosages

Instructions for use for Mexidol indicate such dosages:

1. Serious problems with circulating blood in the brain. Meksidol is prescribed in the first 10-14 days directly into the vein by a dropwise method of 200-500 mg 2-4 times a day. At the end of this period, he is assigned directly to the muscle at 200-250 mg 2-3 times a day for 2 weeks.
2. In cases of non-inflammatory diseases of the brain. Mexidol is administered directly to the vein at a dose of 200-500 mg 1-2 times a day for 2 weeks. After this - directly into the muscle at 100-250 mg per day for the next 2 weeks.
3. To prevent non-inflammatory diseases of the brain. Mexidol is administered directly to the muscle in an amount of 200-250 mg 2 times a day for 2 weeks.
4. With , minor malfunctions of the mental performance and memory loss in elderly patients. Mexidol is prescribed directly to the muscle in an amount of 100-300 mg per day for a period of 2 weeks to 1 month.
5. With , increased craving for alcohol dependence. Mexidol is prescribed in the amount of 200-500 mg directly into the vein by a drop method or directly into the muscle 2-3 times a day for 1 week.
6. With severe purulent and inflammatory processes in the abdominal region. Mexidol is prescribed on the first day either before or after the operation. Dosage is determined depending on the severity of the disease. It is necessary to cancel the drug gradually.
7. Mild severity of necrotizing pancreatitis. Meksidol is prescribed in volumes of 100-200 mg 3 times a day directly into the vein by a droplet or directly into the muscle.
8. The average severity of necrotizing pancreatitis. Prescribe 200 mg 3 times a day directly into the vein in a drip fashion.
9. Severe leakage of necrotizing pancreatitis. In the first day, 800 mg are administered on the condition of administration twice a day. After this, 200-500 mg 2 times a day with a decrease in the daily dose.

Form

Mexidol is produced in as:

• solution;
• tablets.

Solution 50 mg / ml in ampoules of 2 ml and 5 ml.

Tablets that are coated with a white or beige shell have a biconvex shape.

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Overdose and additional indications

Nausea and dryness of the oral cavity, drowsiness may appear. Allergic reactions are possible.

Special instructions

In cases of individual hypersensitivity of patients to the components of the drug, allergic reactions are possible. Patients who drive cars need to take special care.

Interaction with

preparations No specific features are observed with concurrent use of several drugs.

Mexidol is quite well combined with other medicines.

Has the property to reduce the toxic effect of ethyl alcohol.

If necessary, can be taken after taking alcohol.

Use in pregnancy and lactation

Mexidol is not recommended for women during pregnancy and breast-feeding.

Reviews of doctors and patients

Reviews of doctors and patients about Mexidol are mostly positive.

Reviews of doctors

Here's what says doctors:

1. Mexidol is one of the domestic drugs that has proved itself very well. Experience shows that he perfectly fights with disorders of blood circulation, stimulates a decrease in the craving for various addictions, removes the symptoms of neuroses. Still it is good in that it has literally several side effects that are not severely harmful ( Valentinov VS).
2. Patients who suffered from cognitive impairment after the use of this drug observed a significant improvement in general condition due to sufficient supply of the brain with blood ( Egorin KG).

Patient feedback

Patient feedback about Mexidol is also filled with enthusiastic notes:

1. Wonderful thing! Only they are saved. I did not even think that he could save me from so many problems ( Antonina).
2. I suffered a whole year from nightmarish headaches. I had to take pills almost every day to relieve the spasm. I went to a neurologist and he prescribed me Mexidol. Did me terribly prickly injections directly into the muscle, from which the bruises remain. But, in spite of everything, he helped me very well. For a long time already it was not necessary to drink any tablets from headaches and brain activity has improved. I am very happy and I advise everyone to ( Raisa Ilinichna).
3. I was prescribed this drug several times. Well, I think if it's so popular, it will help me. But, as it turned out, this is far from a panacea. Side effects started to appear immediately, and after they passed, it turned out that there was no positive effect. So, not everyone helps. A pity ( Fedor Ivanovich).

Pros and cons of the drug on reviews and practical application of

In general, Mexidol has only positive side:

• perfectly fights with problems of blood circulation in the brain;
• prevents the development of free radical processes, which are provocateurs of other health problems.

In other words, it acts as an excellent antioxidant.

In 90% of cases, he does an excellent job of his tasks, but there are those 10%, in which a side effect is manifested and Mexidol can not interrupt already neglected processes.

Form release and cost

The price of tablets and injections Mexidol is relatively low and is:

• the price of the solution when the drug is delivered directly to the muscle and directly to the vein at a dosage of 50 mg / ampoule in 2 milliliters is 463 rubles;
• the price of the solution when the drug is applied directly to the muscle and directly to the vein at a dosage of 50 mg / ampoule in 5 milliliters will be 436 rubles;
• the price of tablets will be 278 rubles.

Storage conditions and terms

The preparation should be stored in a dry place, non-conductive sunlight with a temperature not exceeding 25 ° C.

Shelf life is 3 years.

Leave at the pharmacy

Let go with the prescription only on the advice of a doctor.

Analogs of

Analogs of Mexidol Mexico, Mexican, Mexident, Mexipiridol, Neurox, Cerekard and others.

They have similar properties and mechanisms of action.

Video: Mexidol - a drug that improves blood flow to the brain

The drug has a wide range of applications in neurology and increases the body's resistance to external influences, has a mass of therapeutic effects and actions.