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What is Ergocalciferol - its role in the prevention and treatment of diseases of the OA

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Ergocalciferol Ergocalciferol( vitamin D2) and other preparations based on it are often prescribed to strengthen bone tissue. The active component of this drug penetrates into the structure of bone tissue and replenishes in it all the necessary substances and vitamins.

Especially often the drug is prescribed for newborn babies, who at first need calcium and phosphorus for the full growth of the body.

Ergocalciferol is a drug that has the second name - vitamin D2.This drug is designed to treat and prevent the occurrence of avitominosis D, as well as hypovitaminosis. The drug refers to fat-soluble vitamins, and is also a regulator of calcium-phosphorus metabolism.

The preparation is formulated in droplets with an oily structure, which are intended for oral administration. Drops are placed in bottles of dark glass with a volume of 10 and 15 ml. Also, the product is available in the form of a pellet with a dosage of 500 IU.One package contains 100 pieces.

The medicinal product contains the following components:

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  • active component - ergocalciferol;
  • auxiliary constituents are refined soybean oil.

The formula of ergocalciferol

Contents of the article

  • Pharmacological profile
  • What indications are prescribed for the
  • preparation When taking vitamin D2 is not recommended
  • How to take and in what dosages
    • Reception during rickets
    • Reception for treatment of orthopedic diseases
    • How to take with osteomalacia
    • Intended for tuberculous lupus
  • Pregnant and lactating agents
  • Cases of overdose
  • Adverse events
  • Special instructions and important nuances
  • Opinion
  • Buy preparata and its analogs

Pharmacological profile

Ergocalciferol affects the calcium-phosphorus metabolism that occurs in the human body. With the influence of certain enzymes, the main constituent element of the drug passes into the state of active metabolites.

These metabolites can freely enter cell tissues through membranes, and bind to receptors in them. As a result of these actions, Ergocalciferol enhances the activation of the synthesis of calcium-binding proteins. And also there is an improvement in the penetration of calcium and phosphorus into the intestinal structure.

An increase in the level of calcium in the blood is observed within 12-24 hours after taking the drug. Therapeutic impact occurs in about two weeks and lasts for six months.

Rapid absorption of the main component of the drug occurs in the walls of the intestine, partial absorption is observed in the walls of the small intestine. If the intestinal tract decreases the gallbladder intake, then the absorption process decreases.

Accumulation of the main constituent element occurs mainly in the bone tissue, in a small amount it can be present in muscle fibers, liver composition, blood composition, small intestine, fatty tissues.

In the liver, the main element of the drug can pass into the state of the inactive metabolite - calcipediol, in kidneys it can pass into the state of calcitriol, the active metabolite.

The main excretion of the drug occurs with bile, through the kidneys is released in small amounts.

Vitamin D and its effect

When is the

medication prescribed? Ergocalciferol and preparations based on it are prescribed for oral administration for the purpose of prevention and treatment in cases of lack of calcium and phosphorus in the following diseases and disorders:

  • rickets;
  • during tetany( convulsions);
  • during disorders of the gland of parathyroid type;
  • in case of osteomalacia - softening of bone tissue;
  • for bone tissue tuberculosis;
  • during treatment of osteoporosis of various genesis;
  • for tuberculous lupus.

osteoporotic bone

When taking vitamin D2 is not recommended

According to the instructions, the drug should not be used in such conditions:

  • with increased sensitivity to vitamin D2;
  • if there is a high level in the body of calcium and phosphorus;
  • during renal osteodystrophy.

With special care and under the strict supervision of doctors, medication is taken under the following conditions:

  • during active tuberculosis;
  • during sarcoidosis;
  • for the elderly at the age of 60 and over;
  • for pregnant women over the age of 35;
  • during urolithiasis;
  • in renal and heart failure in chronic form.

How to take and in what dosages

drop on pipette According to the instructions, the drug should be taken orally. In 1 ml of the oil agent there is 25 000 IU.One drop from the pipette has about 700 IU of active ingredient.

For preterm neonates, the medicine is given as prophylaxis for rickets from the fourth week of life and during the first year of life. In the summer period, the medicine is not given. Every day a child needs 500-1000 IU of funds.

For preterm infants, as well as children who are in unfavorable climatic conditions, the remedy is given from the 14th day of life.

Admission during rickets

During the therapeutic treatment of rickets of the first degree, children receive 10-15 thousand IU daily for about 30-45 days.

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During therapeutic treatment of rickets of the second and third degree, children need to give 600-800 thousand IU of medication daily for about 30-45 days.

During an exacerbation of the disease or a relapse of rickets, therapeutic treatment should be repeated. At repeated treatment every day 400 thousand IU are given about 10 days. The subsequent repeated course of treatment can be made not earlier than 2 months after the first therapy.

Admission for the treatment of orthopedic diseases

People who have various orthopedic disorders and disorders are prescribed 3,000 IU of medication every day for 45 days.

Repeated therapeutic treatment with this drug is carried out no earlier than 3 months after the first course of therapy.

How to take in case of osteomalacia

Patients who have a history of osteomalacia are prescribed a medication of 3 000 IU per day for 45 days.

Assignment for tuberculous lupus

During tubercular lupus, a patient is given 100,000 IU of medication at 24 hours. Patients aged 16 years, a day is given from 25 000 IU to 75 000 IU.

Intended use for pregnant and lactating mothers

For pregnant women and breast-feeding mothers, it is recommended that the drug be given for prophylactic treatment of rickets in pregnant woman and a doctor of newborns.

The medication is prescribed for the 30-32 week of pregnancy. Its reception is carried out in a fractional manner for 10 days. One course of therapy consists of a total dosage of 400,000-600,000 IU.

For women during breastfeeding, the medicine is given every day in a dosage of 500 IU.Accept it until the newborn child begins to take it himself.

Cases of overdose

In case of hypervitaminosis, namely, at an excessive level of vitamin D2, symptomatology associated with hypercalcemia can be observed.

From the initial symptomatology observed:

  • occurrence of constipation or diarrhea;
  • increased dryness of the oral mucosa;
  • frequent headaches;
  • feeling of thirst;
  • state of nocturia, pollakiuria, polyuria;
  • may have anorexia;
  • state of nausea and the occurrence of emetic pushes;
  • occurrence of metallic aftertaste;
  • a feeling of severe fatigue and asthenia;
  • state of hypercalciuria, hypercalcemia.

There may also be a later symptomatology, which manifests itself in the following conditions:

  • urine turbidity;
  • pain in the bones;
  • high blood pressure;
  • the state of the photosensitivity of the eyes;
    feeling drowsy;
  • state of hyperemia, conjunctiva;
  • appearance of skin itch;
  • occurrence of nausea and vomiting;
  • pancreatitis;
  • sharp slimming.

During an intoxication in the chronic form development of an arterial hypertensia, a calcinosis of soft tissues, lungs, kidneys, blood vessels, a problem in body height of the child, occurrence of cardiovascular and renal insufficiency can arise.

At the appearance of the first symptomatology of vitamin D2 hypervitaminosis, it is necessary to immediately stop taking the drug. Also, the patient is given a course of taking vitamins A, B and C.

Adverse events

When taking medication in excessive doses, vitamin D2 hypervitaminosis may develop, caused by high intake of vitamin D. In this case, the following symptoms may occur:

  • state of nausea;
  • poor appetite;
  • headaches;
  • increased body temperature;
  • there may be changes in laboratory tests, namely the appearance of protein in the urine, leukocytes;
  • in addition to the blood levels of calcium can increase, in the blood vessels, kidneys, lungs can appear calcium deposits.

Special instructions and important nuances

When taking Ergocalciferol and its analogs, the following points should be considered: Vitamin D2

  • if medication is prescribed for premature infants, then phosphate should be administered together with it;
  • because the symptomatology and intensity of sensitivity to vitamin D2 is different, in some people, even when taking therapeutic doses, hypervitaminosis may appear;
  • in newborns may have different sensitivity to vitamin, with prolonged admission, some children may experience growth retardation;
  • is not recommended for people who have hereditary hypophosphatemia and hypoparathyroidism;
  • with long-term medication in a large dosage is recommended to conduct studies on the content of calcium and phosphorus in urine and blood.

There is an opinion of

Reviews of doctors and ordinary people who know what is Ergocalciferol firsthand.

Ergocalciferol is a substitute for the well-known Aquadetrim. By action and composition, both agents are similar. But I believe that Ergocalciferol is much more effective and its effect is more extensive. If you compare it with Aquadetrim, in most cases the effect from its reception is visible after a week of intake.

It is especially good for rickets in newborns. Therefore, this drug must be given to children with 4 weeks of life, in order to prevent this disease. But still, while taking a vitamin, you should always undergo a test and take tests for calcium levels.

Pediatrician pediatrician

Ergocalciferol is an excellent remedy for the prevention of rickets in newborn babies, and it can be taken by pregnant and lactating mothers.

During the reception of this remedy, the condition of the bone tissue improves, the lack of calcium and phosphorus is compensated.

Newborn children should be given it from 4 weeks of life and up to a year. In the summer months, the drug should not be taken. Also, the drug is recommended for taking with various orthopedic pathologies, tuberculosis lupus, osteomalacia.

Physician Therapist

The pediatrician prescribed the drug to my son from 2 months. He explained that this drug should be taken to newborn babies for the prevention of rickets. We took it in the autumn and winter to a year. Rickets throughout the period was not.

Of course, it is not clear whether this should be associated with taking this medication or with the physiological characteristics of the child's body.

But, in my opinion, it is necessary to take this remedy for small children, because their body is still weak, and they do not joke with their health!

Catherine, 28

The doctor prescribed a daughter to take Aquadetrim in 5 months, but when I came to the pharmacy, there was no money. In the pharmacy they said that Ergocalciferol is the same remedy for action. Very much surprised by its cost, the medicine is almost 10 times cheaper than the Aquadetrim.

However, there is a drawback - there is no dispenser, so it is difficult to type a solution. I typed it with a pipette. She took her daughter in the fall and winter, strangely enough signs of rickets we did not even have. I think it's all thanks to this drug.

Lyudmila, 22 years

purchase the drug and its analogues

price of one bottle of ergocalciferol is 30 rubles, are also available to purchase its analogs:

  • Akvadetrim;Aquadetrim
  • Alfadol-Ca;
  • Videchol;
  • Van Alpha;
  • ROCALTROL;
  • Ethal;
  • Alfadol;
  • Oxidevit;
  • Tevabon.

Store the medicine in a dry place in the refrigerator. The temperature during storage should not exceed 10 degrees Celsius.

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