Tizanidine is a drug from the muscle relaxant group. It is prescribed for patients suffering from muscular pain, as well as having a number of diseases.
Initially used only for neurological diseases, but due to its analgesic properties, it was used by patients with headache, neuropathic pain and various musculoskeletal pains.
Most often it is prescribed to patients with complaints of osteochondrosis or hernia.
Article content
- Pharmacological action
- Pharmacokinetics of medication
- Indications for use
- Hidden danger of medication
- Mechanism of action
- Instruction for use
- Overdose and additional indications
- What do specialists and patients think about the drug
- Advice on receiving from patients
- Pros and cons of practicalEXPERIENCE
- Cheap and angry
- Drug replacer
Pharmacological action
Tizanidine affects the increased muscle tone, dIts fur is smaller, and at the same time it relieves spasms. In addition, it does not affect skeletal muscle.
Has analgesic effect and reduces the manifestations of both chronic and acute pain.
Pharmacokinetics of the drug
Tablets are absorbed very quickly, which is confirmed by the tests - already literally in an hour the drug is in the blood. The medicine is excreted from the body together with the urine.
Indications for use
This drug is prescribed:
- for painful muscle spasms associated with functional spine injuries;
- for multiple sclerosis;
- after surgery for osteoarthritis or herniation of the intervertebral disc;
- for chronic myelopathy;
- after a stroke;
- with degenerative spinal cord disease and convulsions of central origin.
The hidden danger of the drug
There are reasons why taking Tizanidine may not be safe.
They are called:
- severe liver and kidney disease;
- individual intolerance of the drug;
- age( no prescription for children);
- pregnancy and lactation;
- tablets together with fluvomexamine.
Mechanism of action
Tizanidine stimulates alpha2-adrenergic receptors and thereby inhibits the release of amino acids that stimulate NMDA receptors.
Because of this, at the level of the neurons of the spinal cord, polysynaptic excitation transmissions are suppressed. In addition, the drug does not affect monosynaptic reflexes and skeletal muscles.
Instructions for use
Before using Tizanidine, doctors are advised to read the instructions. The drug is available in the form of tablets and in the form of capsules.
Dosages and methods of application of the drug depending on the concomitant disease and neglect of the disease.
The initial dose of the drug is 2 mg .In this case, the effect of the drug appears a few hours after ingestion, and ends in about 6 hours.
Therefore, the interval between receptions should be 6-7 hours. Gradually, the dosage can be increased to 4 mg. In rare cases, the daily dose of the drug may be 36 mg.
Patients suffering from various kidney or liver diseases should take this medicine very carefully. In addition, you should always consult your doctor.
Overdose and additional instructions
To relieve muscle spasms, you must take Tizanidine in the form of tablets of 2 or 4 mg 3 times a day.
When the patient has a spastic condition of the muscles, the dose should be set by the doctor individually. In no case should the daily norm of the drug be exceeded - 36 mg.
With regard to capsules, at the beginning of treatment, the daily dose of the drug should not exceed 6 mg of , that is, the patient can take only one capsule. The maximum at which the intake rate can be increased is another 6 mg.
There may be side effects when taking medication. Most often, patients feel nauseous, dizzy, drowsy and weak. There is also a decrease in blood pressure and indigestion.
With the use of a medicine along with antihypertensive drugs, bradycardia and hypotension may appear. You should see a doctor if, after taking the drug, the patient feels:
- pain in the right side;
- loss of appetite;
- severe fatigue;
- increase in muscle spasms.
Drugs should not be taken during pregnancy or lactation. And if you can not get by without taking medication, then breastfeeding should be stopped.
Also, you should not take the medicine with alcohol, as it increases drowsiness. Caution should be given to the drug 
patients over 65 years of age.
Children practically do not take the drug and doctors do not recommend it, at least, up to 18 years.
Patients who suffer from kidney failure must definitely reduce the dose. Also, extremely cautiously you need to take pills with heart diseases.
It is not recommended to use the drug before driving a car.
If an overdose of the drug occurs, the first symptoms will be: vomiting, drowsiness and, in extreme cases, coma. At home, doctors recommend using activated charcoal.
If symptoms of poisoning do not go away and intensify, you should seek medical help.
What do specialists and patients think about the drug
Reviews of patients who took tizanidine and doctors.
This drug should be prescribed only in cases of severe pain, since after it can seriously disrupt the work of certain organs. First of all, the liver, kidneys and stomach suffer.
Sergey K., the therapist
Despite the fact that the drug has many contraindications, I do not doubt its effectiveness.
Headaches and muscle pains, multiple sclerosis, nerve pathologies - he copes well with all these problems. Moreover, it is proved by thousands of patients.
Valeria O., the therapist
I, probably, the drug does not fit. Almost immediately after the reception, the head became very dizzy, and nausea appeared. I thought that the body would get used to it and everything would go away, but further problems with the stomach started. I had to ask the doctor to replace the medicine.
Katia, Barnaul
I bought a remedy, as the exacerbation of the cervical syndrome began, and Tizanidine was prescribed by a doctor. There were several side effects, for example, fatigue and low blood pressure. The main thing is that the drug helped.
Alena, Omsk
After the operation on the spine for a long time did not take strong drugs, but one day the pain returned. Rushed to the hospital, where the doctor prescribed tyzanidine. I took it for the night, and in the morning a miracle happened - everything was over! Nothing hurts and no unpleasant symptoms. Like this.
Victor, Yekaterinburg
I am an athlete, so often I suffer from intervertebral hernias. The doctor prescribed tizanidine, but warned that there could be sleep disorders, etc. In general, it should be taken only as a last resort, but it actually helps to reduce the pain.
Glory, Moscow
Tips for receiving patients from
It's best to start taking this medicine from small doses, because you never know how the body will react to it. By the way, sharply stop drinking it, too, do not.
Olya, Moscow
Since the drug causes drowsiness very much, it can sometimes be used as a sleeping pill.
Andrey, Yalta
I had a lot of "pobochek", so I do not recommend drinking this drug for nothing. Saying "a lot", I mean that I had almost all the signs of a real poisoning.
Anna, Murmansk
Advantages and disadvantages of the practical experience of
The advantages of the drug are that it really effectively helps with severe muscle pain.
Patients note its therapeutic properties primarily in osteochondrosis and intervertebral hernias.
Cons - in a large number of contraindications .Even patients with excellent health sometimes complain that after taking this medication, various body disorders appear.
Therefore, you need not only listen to your doctor, but also read the instructions for use.
Cheap and angry
The medicine is released in several variations. The most common are tablets of 2, 4 and 6 mg. In the packaging they are usually 30 pieces. Also there is a preparation in capsules - 6 mg, 10 pieces per pack.
Price Tizanidine approximately from 100 to 150 rubles .
The drug should be stored out of the reach of small children and at a temperature of no higher than 25 ° C.Usually the shelf life of the medicine is not more than 3 years. Sold only by prescription.
The medicine substitute
The Russian equivalent of Tizanidine is Sirdalud.
