Nurofen medicinal preparation is intended for removal of inflammatory processes, anesthesia at any kinds of a painful syndrome and with the purpose of decrease in temperature.
Children's Nurofen is also available for adult treatment. It belongs to the group of propionic acid derivatives. It is a nonsteroidal anti-inflammatory drug( NSAID).
The tablets are covered with a white shell, a round shape with an inscription in the middle. The effervescent tablets are white, round, flat, with a characteristic rough surface. The aqueous solution obtained as a result of the interaction of the tablet with the liquid is clear, colorless.
Table of contents
- Pharmacological action
- Pharmacokinetic profile
- Composition and preparation
- Ingredients
- Mechanism of action
- Made specifically for children
- Indications for use
- Limitations and contraindications for use
- Instructions for use: dosages and charts
- Instructions for use:
- Side effects
- Special instructions
- View from the side for completeness
- Purchase and storage
PharmacologicalCorollary
has analgesic, similar to the analgesic, antipyretic and anti-inflammatory effects.
The effect is mild, but stable, due to biochemical reactions inhibiting the synthesis of prostaglandins, carried out by blocking an enzyme called cyclooxygenase.
Pharmacokinetic profile
Absorption and distribution of the drug Nurofen occurs immediately after ingestion of the tablet, syrup or after application of the ointment.
Feature - the active substance of the drug ibuprofen is rapidly absorbed from the digestive tract. The binding of the substance to the plasma proteins is more than 85%.
The metabolic processes occur in the liver, where the inactive form of substances is transformed into an active one. Excretion is performed with urine, conjugates and bile within 2-3 hours after administration.
Composition and form of preparation
Nurofen is available in the form of:
- tablets;
- gels;
- ointments;
- candles;
- capsules;
- suspensions.
Ingredients
The main active substance of the drug is ibuprofen. The auxiliary substances that make up Nurofen:
- sodium in various compounds;
- stearic acid;
- silicon;
- talcum powder;
- gum;
- sucrose;
- titanium;
- macrogol.
Packings of tablets can be produced in usual cardboard packages of 6-12 pieces or in plastic containers of 12 pieces( most often effervescent).
Nurofen Express:
Mechanism of Action
The drug suppresses the formation of enzymes, which affect the formation and start of inflammatory processes, pains of a different nature and origin.
After using the drug, the synthesis stops and the person feels relieved. The process of suppression, and therefore, the action of the tablet lasts up to 8 hours.
Made specifically for children
Children's Nurofen is recommended to be used only after preliminary consultation with a specialist, a remedy is available in the form of a suspension, syrup or ointment.
Suspension and syrup are for oral use, you can dilute it with water a little.
Approved for use from 3 months to 12 years.
For convenient measurement of the amount of the drug in the package there is a special syringe. It is recommended to shake the bottle with the syrup before use.
Also children's forms of the drug are issued in the form of candles, which can be used from 3 months.
If side effects occur during application of Nurofen, the drug should be discontinued immediately and consult a doctor.
Indications for use
Specialists prescribe Nurofen Express if the following diseases were diagnosed:
- rheumatism;
- pain in the back;
- joint pain;
- arthralgia;
- migraine in various manifestations;
- neuralgia;
- acute toothache;
- influenza;
- fever;
- ARVI;
- algomenorrhea.
The drug is also prescribed for the diagnosis of myalgia. Children's Nurofen is effective in the period of teething, is prescribed strictly according to the instructions to the kids from 5-6 months for the removal of painful sensations.
Limitations and contraindications for the use of
Although the drug is approved for use by children from the age of 12, it has a number of contraindications that must be considered when initiating treatment. Consultation and examination with a doctor will make sure that the drug is safe to use.
Contraindications to the use of Nurofen:
- of the disease of the digestive tract - ulcer, erosion, colitis, Crohn's disease;
- diseases of the cardiovascular system( heart failure);
- arterial hypertension;
- bronchial asthma;
- urticaria;
- allergic reactions to acetylsalicylic acid;
- diseases of the eye - disruption of the optic nerve, color perception, amblyopia, scotoma;
- hemophilia;
- hypocoagulation;
- leukopenia;
- diathesis( hemorrhagic form);
- liver and kidney disease in pronounced form;
- hearing problems;
- disease of the vestibular apparatus;
- pregnancy( the entire period, but with extreme caution from the 3rd trimester) and lactation;
- age of child under 6 years old( usual drug);
- Hypersensitivity to the components that make up the drug.
Also with caution and only after consulting a doctor, Nurofen may be used, if available:
- gastritis;
- bleeding in the gastrointestinal tract;
- autoimmune diseases.
This is why self-receiving is not recommended.
Instructions for use: dosages and charts
If the doctor has not prescribed any other treatment, then according to the application instructions supplied by the manufacturer, for adults( people over 12 years of age) treatment should begin with a dose of 200 mg Nurofen. Number of receptions - no more than 4 times a day.
The maximum amount of a drug taken per day is 1200 mg. If the permission of the attending physician is obtained, you can increase the medication intake to 400 mg / dose, but not exceeding the maximum value per day.
Children aged 6 to 12 years - 200 mg not more than 4 times a day.
The gap between the use of the drug should be 6 hours. The maximum dose per day for a child of 6 years is 1.2 g or 6 tablets. It is recommended to wash them with water. The effervescent form should be dissolved in 1 glass of water.
Ointments for pain relief and other ODA problems are applied to the problem area and rubbed with massage movements.
Repeat the procedure 2 times a day. In case of severe pain, you can apply Nurofen ointment 3 times a day.
Cases of overdose
In cases of overdose - exceeding recommended by the doctor or prescribed in the dose, the person will determine this for the following manifestations:
- abdominal pain;
- nausea;
- weakness;
- drowsiness;
- headache.
In rare cases, there is a response from the body:
- depression;
- coma;
- lowering of blood pressure;
- development of kidney disease;
- tachycardia;
- respiratory arrest.
Usually, in order to feel an ailment, it is required to exceed the dose to 1.5 g. Serious changes occur after double exceeding the maximum dose.
In the case of using the drug to treat a child, serious consequences can occur with a slight increase in the maximum dosage - much depends on the age and body characteristics, so consultation with a doctor is a must.
Side effects of
Side effects appear in most cases not immediately, but on 2-3 days after the start of the drug. Most often expressed in problems and disorders of the digestive tract, dry mouth, inflammation of the gums and mucous membranes. Also there are headaches, less often a migraine.
Sometimes there is cystitis, irritation and dry eyes, ringing and / or tinnitus. Allergic manifestations of different intensity are possible.
Respiratory system may respond with dyspnoea or bronchospasm. Intensive sweating also informs the person that the drug should be discontinued.
Special instructions
It is not recommended to take alcohol during treatment with preparations containing ibuprofen. It is important to remember that the restrictions on admission apply to people with diabetes mellitus, who are on a special diet and with intolerance to fructose.
In the event that the kidney and liver functions are mildly disturbed, admission is allowed - the doctor counts the dose and the number per day. In the event that the pathology is serious - you can not use the drug.
It is not recommended to take several drugs from the NSAID group at the same time. Thrombolytic drugs also do not work well with Nurofen. If a person undergoes treatment and takes various medications, it is necessary to undergo examination and consultation, as some drugs reduce their effectiveness in the presence of ibuprofen.
During pregnancy( before the 3rd trimester), doses of the drug are given based on the minimum values. In the period of lactation - a complete ban on taking the drug. Child age from which you can take Nurofen for adults is 12 years old.
View from the side for completeness of the picture
From the feedback and advice of doctors, as well as their patients who take Nurofen, you can get a lot of useful information.
I started to take Nurofen on the advice of a friend. Carefully read the instructions, especially contraindications, I realized that the remedy suits me. Valid for 10 hours, that is, I take 2 times a day. Usually I have 3 days to fully recover.
Karina, 38
I try not to take medicine at all, but I trust Nurofen - it's time-tested. With bruises and other minor injuries - Nurofen ointment is the most. The whole family is satisfied with the result.
Valeria from Krasnoyarsk
Recommendations for use - do not exceed the indicated dosages. I did not read it, then I suffered from digestion problems for a long time. But if you strictly follow the dosage, then there is no problem, and the effect is felt almost instantly.
Alina
As a doctor I want to say about Nurofen the following - the remedy really works, but you can not exceed this dosage, because excess can put strain on the body.
Therapeutist with profforma
Purchase and storage of
Price of Nurofen depends on the form of release and location of the pharmacy:
- tablets from 97 rubles to 220 rubles;
- suspension - an average of 180 to 200 rubles;
- for children Nurofen - 250-300 rubles;
- gel or ointment - from 160 rubles.
From pharmacies is released freely, without a prescription. The drug should be in a dry place inaccessible to children at a temperature of up to + 25 ° C.
Shelf life up to 3 years. Analogues: Advil, Bonifen, Artrocam.