The use of antidepressant Cipramil in depression, panic attacks and stress

Cipramil is an antidepressant that refers to selective serotonin reuptake inhibitors( SSRIs).

Pharmaceutical form of the drug is tableted. Tablets have a membrane in the form of a film of white color. Oval capsules, a notch is placed on each side: at a dose of active substance 40 milligrams - marking C / R, at 20 milligrams - C / N.

Tablets are in blisters for 14 pieces. Number of blisters in a cardboard package: one, two or four.

Composition of the drug

Citipram includes an active ingredient such as citalopram hydrobromide. In tablets of 40 mg - 49.96 milligrams, 20 mg of - 24.97 milligrams.

The medicine also contains the following excipients:

• magnesium stearate;
• lactose monohydrate;
• microcrystalline cellulose;
• Copovidone;
• cornstarch;
• of croscarmellose sodium;
• 85% glycerin.

The tablet shell has in the composition of titanium dioxide, macrogol and hypromellose.

Pharmacological profile

Cipramil exerts such a curative effect on the body:

• elimination of irritability, aggression, apathy, abulia, feelings of anxiety and fear;
• getting rid of obsessive thoughts;
• improved mood;
• removing the sensation of dysphoria;
• weakening of mental overstrain.

The medication acts on the synapses of neurons, blocking the re-uptake of serotonin, a hormone that prevents the development of depression and stress.

After stopping the medication, the therapeutic effect persists for one to two weeks.

Accumulation of an insignificant concentration of the active substance is observed only a few hours after taking the tablets. Up to 80% of the accumulation of the active component occurs due to the binding of plasma proteins. Removal of the remnants of the drug occurs about a day later with urine.

Scope and contraindications

Cipramil is prescribed in such cases:

• depressive states of various origins and structures;
• obsessive-compulsive disorder;
• panic attacks;
• stress states;
• psychoemotional disorders with the presence or absence of agarophobia;
• phobia of various genesis.

The remedy is also used when the patient has an increased level of anxiety, a sense of fear, aggressiveness, nervousness, apathy, irritability, disturbed sleep, tearfulness, dissatisfaction with life and unwillingness to live, suicidal behavior, self-doubt.

Cipramil has a relatively small list of contraindications to admission.

These include:

• lactase deficiency resulting from a hereditary factor;
• syndrome of QT interval increase;
• hypersensitivity to galactose;
• disrupted absorption of galactose or lactase;
• age to eighteen years;
• serotonin syndrome;
• frequent pressure jumps( increase or decrease);
• high sensitivity to the active or auxiliary component of the drug;
• concurrent use of MAO inhibitors.

For such diseases as bradycardia, diabetes mellitus, arrhythmia, hypomagnesemia, myocardial infarction, hypokalemia, hepatic, renal and heart failure the drug is used with caution. Also, under medical supervision, a drug is used to treat patients prone to bleeding.

In the elderly, dosage adjustment is necessary.

Dosage, duration and treatment regimen

Usually, the medication is consumed once a day. With depressive states, a dose of 20 mg is first prescribed, then the specialist can increase the dosage depending on the severity of the disease, as well as the individual characteristics of the organism to 40 mg.

In panic disorders, the initial dose is the floor of the pill at a dosage of 20 mg, over time it is increased to 40 mg.

The tablets are drunk with water. Their use is not dependent on eating. You can take the medicine at any time, but it is better that the interval between doses is twenty-four hours.

Overdose and what to do with it

In cases of overdose, symptoms may develop:

• vomiting;
• drowsiness;
• epileptic seizures;
• convulsive condition;
• cyanosis;
• arrhythmia.

In case of a serious condition, a coma may occur.

Overdosage requires gastric lavage. Convulsions are removed by Diazepam.

Side effects of

When using Cipramil, side effects and reactions from such organs and their systems are possible:

• respiratory - epistaxis, yawning;
• digestive - constipation, vomiting, diarrhea, organ hemorrhage, hepatitis;
• cardiovascular - tachycardia, hypotension, bradycardia;
• Nervous - paresthesia, dizziness, serotonin syndrome, sleep disorders, convulsions, fainting;
• skin and subcutaneous tissue - increased sweating, rashes and itching on the skin, angioedema, purpura;
• genitourinary - ishuria, profuse period, uterine bleeding.

In addition, there may be problems with the reproductive system. Often there is myalgia, joint pain, ringing in the ears, vision impairment, thrombocytopenia, loss of appetite, weight loss, hypokalemia, hallucinations, sleep disturbance.

Special instructions

Patients whose profession is associated with the need for increased attention and psychomotor actions, it is desirable to cancel the medication or stop the activity for a while.

Therefore, it is necessary to use the medicine with care when driving vehicles and controlling complex mechanisms.

In connection with the psychotropic effect of the drug, it is not recommended to drink alcohol-containing drinks during the course of therapy.

The instructions for use say that Cipramil with caution and under the supervision of a specialist is accepted for kidney pathologies. However, in this case, treatment does not require dosage adjustment.

For liver diseases, the dosage is set by the doctor, however the dose should not exceed 20 milligrams per day.

Interaction with certain medicines

With the use of serotonergic drugs along with Cipramilum, the effect of these drugs is possible.

During simultaneous reception with MAO inhibitors, intoxication results from a high concentration of serotonin, after which a hypertensive crisis may occur. Therefore, their use is contraindicated.

When cimetidine is used, the blood level of the citalopram increases. Therefore it is not advisable to apply high doses of the drug.

Special patients

Cipramil may be given during pregnancy if the risk to a future baby is lower than the benefit for a pregnant woman. Do not sharply interrupt the medication when bearing a child.

Late pregnancy may have a negative effect on the formation of the fetus.

Children are not allowed to drink an antidepressant.

Opinion about medication

Opinion of practicing psychiatrists and feedback from patients who take or take antidepressant Cipramil.

Testimonials of patients who used the remedy show that it is difficult to get out of the medication - there is an addictive syndrome and the effect of withdrawal. Therefore, almost everyone as one is advised to gradually reduce the dose to interrupt treatment.

The advantage of Cipramil is the high effectiveness of the medication and the minimum list of contraindications. Among the shortcomings are high cost, the possibility of addiction and the development of side effects.

Purchase of the drug and its analogues

Price Cipramil is from 1700 to 2100 rubles. Keep the drug is recommended in places difficult to reach at children, at room temperature. Shelf life - 5 years from the date of production.

Cipramil can be replaced with drugs that have the same composition and similar effects on the body:

• Citalopram;
• Pram;
• Citol;
• to Siozam;
• Citalolin;
• Oprah;
• Died;
• Citalon;
• Sedopram;
• Citalift.