Arthraldol is available in the form of a lyophilizate for injection, which contains active ingredient chondroitin sodium sulfate, which has a regenerative effect on the soft tissues of the joints.
Also, the preparation is available in the form of an ointment of 5% with the same active substance for external use in pathological processes, in which the mobility of the joints decreases and degenerative changes occur in the cartilaginous tissue of the joints, spine, and ligaments.
Table of contents
- Pharmacological action
- Pharmacokinetics of drug
- Indications for use
- Admission is not recommended
- Mechanism of action
- Instruction for use
- Forms of release
- Dosages and administration methods of the drug
- Overdose and special instructions
- Special instructions
- Interaction with other drugs
- Independent medical opinion
- Patient's opinion
- Tips for receiving patients
- Pros and Cons of feedback and practical experience
- The cost of the drug
- Conditions and periods of storage
- How to replace the drug
Pharmacological action
The action of the drug causes active resistance to the development of inflammatory processes in the area of the location of the cartilage tissues of the joints.
Chondroitin sulfate stimulates the production of proteoglycans and promotes the regeneration of the cartilaginous tissues of the subchondral bone.
The active substance is a high molecular weight mucopolysaccharide, which affects the metabolic processes of calcium and phosphorus in the body, serves as a calcium protector in the bone, inhibits the activity of enzymes that decompose into cartilaginous tissues.
Because the drug blocks the release of mediators of the pathological process into the synovial fluid, which occurs through the macrophages of the synovium and through the synoviocytes, the in the patient reduces the pain sensations of .
This is the analgesic effect of the drug. The drug slows the production of prostaglandin E2 and leukotriene B4, acts as a chondroprotective anti-inflammatory drug.
Pharmacokinetics of the drug
Bioavailability of the drug at a level of 15%.The highest concentration reaches in the blood plasma after an hour, the period of excretion from the body is 48 hours. Systemic absorption does not possess, is excreted by the kidneys.
By its structure, Artradol is similar to Heparin and can withstand the formation of fibrin clots in the soft tissues of the joints.
Indications for use
Diseases associated with degenerative changes in cartilage tissue of the joints of the limbs and spine: 
- osteoarthritis - as part of complex therapy;
- spondylarthrosis involving soft tissues in the process of destruction;
- osteochondrosis with dystrophy of vertebral disks and impairment of depreciation;
- the initial stage of development of arthrosis.
Admission is not recommended
The drug is not prescribed for children, pregnant women and women during lactation, as well as people who are prone to bleeding, with ulcers and thrombophlebitis.
Mechanism of action
Artradol enhances resistance to inflammatory processes by stimulating the production of proteoglycans, restraining calcium in bone tissue, prevents destruction of connective tissue.
As the drug enhances the production of joint fluid, the mobility of the joint increases, and soreness disappears. Regulation of phosphate-potassium metabolism of the drug leads to regeneration of the cartilage tissue, its further recovery.
Instructions for use
Artradol is administered intramuscularly at 0, 1 gramme through the day. In the absence of negative reactions, the dose can be increased after 3 injections.
The lyophilizate from the ampoule is dissolved in 1 ml of water. The injections are done by courses of 25 to 35 injections.
Forms of release
The drug is available as a lyophilizate in ampoules, 0.2 grams in a box of 10 ampoules. Also, an ointment of 5% is produced, in a glass jar 30 grams.
Dosages and methods of application of the drug
Injections are used every other day, with a good body reaction, if necessary, on the recommendation of a doctor, you can double the dose.
Ointment is applied externally several times a day in the absence of allergic reactions to the drug.
Overdose and special instructions
In case of an overdose of the drug, there may be changes in blood counts and disruption of the coagulation process.
At the injection site, hemorrhagic changes may occur, as well as local allergic reactions in the form of itching, redness of the skin, local edema may begin.
Special instructions
Special instructions include monitoring blood clotting readings, it is recommended the use of other drugs for suspected stomach ulcer, colitis. 
It is recommended to refrain from taking alcoholic beverages directly in the first hours after the injection.
In case of impaired renal function, it is necessary to initiate injection with caution. With impaired liver function, it should be monitored by blood tests and liver tests.
Children's age is a limitation in taking the drug.
Interaction with other drugs
Using injections of Artradol simultaneously with fibrinolytics, various antiaggregants, anticoagulant drugs, it is necessary to control the clotting characteristics of the blood, since the drug enhances their effect.
Independent medical opinion
The doctors' comments on the Artradol preparation can be studied below.
To patient K. I appointed Artradol. Some time ago, the patient suffered a knee injury and suffered from pain, almost could not, for example, walk on the stairs. There was a course of injections, now the patient went on the mend, it took about three months from the start of therapy. I see positive dynamics in both pictures and the condition of the patient's knee.
Trauma doctor, Desnitsky G.V.
Assigning this drug intramuscularly, I primarily aim to slow the developed inflammation process, to prevent the final disintegration of tissues and affected areas.
When I see that the patient is well tolerating the drug, I increase the dose. The therapeutic effect of this drug is noticeable not immediately, but persistently persists a few months after the start of the course. "
Orthopedic physician, head of the private clinic Pyshkova O. E
I work as a radiologist in the orthopedic center. We are treated by different patients, many undergo long-term courses of therapy, someone needs surgery. And so, and with the transferred operation and when it is possible to do without surgery, the drug works wonders.
I can see from the pictures how progressively the changes in the state of tissues are in both posttraumatic therapy and in complex diagnoses related to the age characteristics of patients.
Degenerative processes in the cartilaginous tissues weaken, new islets of a new strong cellular system appear, Artradol does its job. I am pleased with this drug »
Radiologist, Karasev VV
Opinion of patients
After the course of pain, the knee pains have significantly decreased, I do not even remember them. I was given 25 injections and I hope that I will not need any more.
Hilova T., retired, orthopedic patient for 4 years
I was prescribed a course of taking medication after a trauma. I had a damaged hip joint. I already tried to use other drugs, but the effect did not come.
Right now, just after I was done more than half the course, I began to feel relieved. So far, it's too early to do, but I hope that it will also improve my joint
Benjamin, 29, athlete
Tips for receiving patients from
Many patients who have undergone ARTrDol therapy note a significant improvement in joint motor function,side effects.
Treatment of the drug is not the first time, I apply its third course.
Although a long course of injections is necessary to survive, but persistently retains the effect of it. I advise patients especially to pay attention to their condition in the cold period of the year, then to apply the medicine to maintain the functions of the patient joint and to reduce their painful sensations.
Patient of the orthopedic clinic Garipova N
Pros and cons of reviews and practical experience of using
The drug has almost no side effects, after its application in all cases, there is a positive trend.
The cost of the drug
The drug is issued in ampoules, 1 ampoule contains 2 ml of the drug.
In the box there are 10 ampoules and in the form of an ointment with 5% packaging of 30 grams in a jar of glass.
Price in rubles per package with 10 ampoules of lyophilizate Artradol ranges from 320 rubles to 680 rubles .
The price of the ointment is about 150 rubles per bank.
Terms and storage terms
Store ampoules in a dark place at a temperature of no higher than 25 degrees for 3 years in a dark place. Shelf life of the ointment is 3 years, the required storage temperature is from 2 to 20 degrees Celsius. It is recommended to keep it out of the reach of children.
Ampoules are dispensed in a pharmacy under the prescription of a doctor, ointment without a prescription, on a free sale.
How to replace the drug
Treatment of cartilaginous articular tissues can also be carried out with the full analogues of Artradol in composition:
- Chondrolon;
- Chondrogaard;
- Chondroitin;
- Nimesil;
- Glucosamine.
