Pharmaceutical of Elbon is produced by the Russian company "MC ELLARA".Its main function is stimulation of the processes of restoration of cartilaginous tissue.
The drug is available as a solution for intramuscular injection. The kit itself contains ampoules with a drug substance( 6 pieces, solution A) and a solvent for them - a 2.4% solution of diethanolamine( R-B).
Also available on sale is a preparation in the form of a powder for oral administration. Produce it on 20 bags in a package.
Another form of the drug pill, but they are on sale very rarely.
Contents of the article
- Pharmacodynamics and pharmacokinetics
- Indications for use
- When should I not use the drug
- Intended use for pregnant women and children
- What adverse effects may occur?
- Treatment and dosage regimen
- Special instructions
- Pharmaceutical interaction
- Purchasing and storing
- From the practice of doctors and their patients
- If there was no drug in the pharmacy. ..
Pharmacodynamics and pharmacokinetics
The pharmaceutical activates the process of cartilage regeneration. The active substance is glucosamine sulfate.
The substance relieves pain syndrome and eliminates inflammatory processes, replenishes the lack of glucosamine in the body, activates the production of proteoglycans and hyaluronate, restores articular cartilage, inhibits joint destruction, relieves pain, reduces the need for non-steroidal anti-inflammatory drugs
When ingested, 90%.When administered orally, the bioavailability is 26%.Half-life with oral intake is 70 hours.
Therapeutic effect is usually observed after 2 weeks from the start of treatment and persists up to 8 weeks after the end of the course.
Indications for use
The drug is included in the treatment regimen for patients suffering from:
- primary and secondary osteoarthritis;
- with osteoarthritis;
- with spondylarthrosis.
When should you not use the drug
Absolute contraindication to taking the drug are: 
- individual intolerance of the active substance and auxiliary components;
- phenylketonuria;
Because of the lidocaine included in the injections of Elbon, they are contraindicated:
- when myocardial conduction is disturbed;
- for acute heart failure;
- with epileptiform cramps on lidocaine in the anamnesis;
- in severe liver and kidney pathologies;
- myasthenia gravis;
- in the period of bearing of the child;
- with natural feeding;
- in pediatrics up to 12 years.
The relative contraindications for prescribing the drug are:
- bronchial asthma;
- chronic heart failure;
- diabetes mellitus;
- reduced pressure;
- individual intolerance to seafood, especially shrimp and soft-bodied.
Administration of the drug to pregnant and children
The drug is contraindicated for use in pregnancy, as there is no reliable data on the safety of the drug in this category of citizens.
Treatment with Elbon's pharmaceutical is not compatible with breastfeeding, if necessary, the child should be transferred to an adaptation mix.
This medication is not prescribed for children under 12 years of age due to a lack of safety data.
What unwanted effects can occur?
During therapy, the following side effects may occur:
- On the part of the digestive system : in some cases - bloating, loose stools, constipation;because of the lidocaine included in the
composition, nausea and vomiting are possible. - Allergy : in rare cases, it is possible to urticaria, itching;lidocaine is possible anaphylaxis.
- Cardiac and vascular lesions of may cause a violation of myocardial conductivity( due to lidocaine).
- All side effects from the CNS are caused by lidocaine: drowsiness, double vision, headache, dizziness, paresthesia of the tongue and oral mucosa, tremor, euphoria, disorientation.
The drug is contraindicated in severe CRF.When prescribing pharmaceuticals, patients with renal insufficiency need constant medical supervision.
When prescribing a drug, patients with severe hepatic impairment need to monitor the patient's condition.
Treatment and dosage regimen
In injections, the Elbone preparation is intended for intramuscular injection.
The solution is prepared by mixing in a single syringe a solvent( 1 ml) with a solution of the preparation( 2 ml).Enter the finished solution intramuscularly 3 ml 3 times a week.
Powder is taken once a day, after dissolving the contents of the sachet in 200 ml of water. Tablets are prescribed either 600 mg 3 times daily or 750 mg 2 times. At the same time, one can take powders and inject the drug.
The course of treatment is 4 to 6 weeks. If necessary, on the recommendation of a specialist, the course can be repeated after 2 months.
Since the therapeutic effect in most patients is observed only after 2 weeks, at the beginning of treatment it is permissible to take non-steroidal anti-inflammatory drugs.
To date, not one case of overdose has been reported. There is no specific antidote. Treatment is symptomatic.
Special instructions
Due to the content of lidocaine during the injection of the drug, care must be taken when driving vehicles and working in hazardous production.
Powders and tablets do not reduce the concentration of attention, they can be taken while driving a car.
When hypersensitivity to seafood increases the risk of allergic reactions on the background of treatment with Elbon.
Pharmaceutical interaction
In conjunction with other medicines, Elbon's treatment has the following effect:
- preparation is allowed to combine with NSAIDs, paracetamol and glucocorticosteroids ;
- Cimetidine and Propranolol reduce hepatic clearance of lidocaine, and as a result, the likelihood of
toxic effects increases; - should not be used simultaneously with Aymalin, Phenytoin, Quinidine, Amiodarone, Verapamil because there is a risk of reducing the force of the heartbeat;
- in combination with β-adrenoblockers increases the likelihood of bradycardia;
- with a parallel appointment with cardiac glycosides observed a decrease in the cardiotonic effect;
- for one-time use with muscle relaxants may enhance their effect;
- Prokainamide in combination with lidocaine increases the likelihood of brain stimulation and the appearance of hallucinations;
- is not acceptable for the combination of lidocaine with with hypnotics and sedative pharmaceuticals , as the likelihood of CNS depression is increasing;
- for intravenous administration of hexobarbital or thiopental sodium , while treatment with Elbones injection forms( due to lidocaine), respiratory arrest is possible;
- also impairment of respiratory function is possible with simultaneous admission with Polymyxin B ;
- lidocaine enhances the action of monoamine oxidase inhibitors ;
- may decrease the effectiveness of hypoglycemic drugs, Doxorubicin, Teniposide, etoposide .
Purchase and storage of
Store the pharmaceutical product at a temperature of no higher than 25 degrees, in a darkened and inaccessible place for children. The drug is dispensed from the pharmacy strictly on the prescription form.
The price for powders and injections of the Elbon is approximately the same and ranges from 1000 to 1500 rubles, depending on the regions of the Russian Federation.
From the practice of doctors, as well as their patients
The comments of patients and specialists who practice the use of the Elbona tool give an insight into how things stand in practice.
I had constant pain in my back. The doctor prescribed me 12 injections of Elbona. A puncture half the course noted that the pain was not so strong. By the end of the treatment, the pain syndrome had passed completely. I have been feeling good for six months now.
The drug was well tolerated, the injections were completely painless. Maybe the tool is not cheap, but the effect of it lasts a long time.
Svetlana, Kazan
Elbon preparation works well for primary and secondary osteoarthritis, with destructive processes in the spinal column. Most patients tolerate it well.
All side effects are mainly due to lidocaine, so it is advisable to take oral dosage forms instead of injections.
Natalia Alexandrovna, rheumatologist
Despite the high effectiveness of the drug, self-medication is not permissible for them. Only a doctor, assessing the general well-being of the patient, can choose the right treatment regimen.
If there was no drug in the pharmacy. ..
The following structural analogs of the drug are on sale: 
- Don;
- Unium;
- Glucosamine sulfate.
Analogues for the therapeutic group:
- Alflutop;
- Structum;
- Chondrolon.
Substitution of Elbone preparation for its analogs is possible only after consultation with a specialist.
