Phybofide is an anti-inflammatory, non-steroidal drug designed to alleviate pain syndrome with tendon, ligament, muscle, skin and lymphatic vessels.
The drug reduces edema, reduces pain and stiffness in the joints after prolonged resting, for example, in the morning after sleep.
Available in the form of a gel and cream for external use. Cream and gel Febrofid stored in aluminum tubes with a capacity of 30 g and 50 g, packed in a cardboard box along with instructions for use.
Table of contents
- Pharmacodynamics of
- Pharmacodynamics of
- Pharmacokinetic properties of
- Composition of
- Mechanism of action
- When application of ointment is not recommended
- Instruction for use
- Overdose and side effects
- Special instructions
- Interaction with other medications
- on the use of
- Pros and cons of
- Purchase and storage of
- Similar drugs
Pharmacodynamics withCOROLLARY
Febrofid active ingredient of the drug is ketoprofen known properties such as anti-inflammatory and analgesic effect. This is due to its ability to inhibit the synthesis of prostaglandins, which are responsible for the swelling and pain in the focus of inflammation.
The drug reduces pain syndrome and unpleasant sensations in the joints, muscles, ligaments at rest and in motion, relieves edema and swelling.
Pharmacokinetic properties of
The gel / cream is rapidly absorbed into the skin, and the active component binds to plasma proteins approximately 99%.
Metabolized ketoprofen in the liver, the properties do not accumulate in the body. It is excreted through the urine as metabolites( 80%) and unchanged( 20%).
Ingredients
The composition of Fefrofid includes:
- the main component - ketoprofen lysine salt;
- auxiliary inclusions - macrogol-200, carbomer, trolamine, purified water and others.
Mechanism of action
The agent is rapidly absorbed into the skin, the active ingredient is metabolized in the liver, and is subsequently excreted in the urine( 80% as metabolites, 10% unchanged).
The mechanism of action of the drug is based on the suppression of the synthesis of prostaglandins, due to which a rapid anti-inflammatory and analgesic property is observed, a reduction in pain syndrome and removal of edema from the affected area.
Indications for use
The drug is indicated for patients suffering from such problems as: 
- diseases of the musculoskeletal system( osteochondrosis, sciatica, lumbago, exacerbation of gout, rheumatoid arthritis, synovitis and others);
- muscle pain;
- various injuries of the musculoskeletal system( damage to ligaments and tendons, muscle contusions, post-traumatic pains, stretching, etc.).
When ointment is not recommended
Despite a wide range for the use of medication, there are a number of contraindications.
The drug is not recommended for use:
- if there is an individual intolerance to the active ingredient or auxiliary inclusions;
- on open extensive wounds, eczema, infected skin lesions;
- for women in late pregnancy( third trimester) and lactating mothers;
- for children under 15 years of age.
Use with caution and only as directed by a physician should patients with gastrointestinal diseases, with kidney and liver functioning, suffering from bronchial asthma and heart failure, and women in the first and second trimesters of pregnancy.
In this case, the drug is prescribed only by the attending physician and in strictly specified doses in order to avoid undesirable consequences.
Instruction for use
Gel The fobrofide is used only externally.
A strip of gel( cream) 3-5 cm long is applied to the skin surface at the site of inflammation or damage and rubbed with light massaging movements 2-3 times a day.
No bandages or bandages are necessary because the product does not stain, does not stain clothing and does not contain dyes.
Overdose and side effects of
Absorption of the drug is very low, and therefore, an overdose is unlikely, such cases have not been established by practice.
Excessive use of the drug, as well as individual sensitivity to the active ingredient, can cause various allergic reactions, skin exanthema, flushing, purpura and others.
Special instructions
Do not apply to the damaged skin and mucous membranes. If side effects occur, immediately stop using the drug and seek help from a specialist.
Interaction with other drugs
Incompatible with tramadol solution. 
Prolonged use with other non-steroidal anti-inflammatory drugs may lead to impaired gastrointestinal function.
Application of the drug in the parallel use of oral anticoagulants, heparin, thrombolytics increases the risk of internal bleeding.
Opinion of Doctors
Reviews of Experts on Gel Febrophide.
I am a neurologist with a long history of work. Gel Febrofid I apply in practice for a long time, as an effective local anesthetic for lumbago.
I recommend using it to my patients in combination with other medications( injections, manual therapy, tablets) to relieve the pain syndrome and alleviate the condition.
Nikolai Sergeevich
The gel is well suited for the removal of mild edema, sprains, minor bruises. The ketoprofen contained in it will quickly relieve the pain for a short time.
Another drug-analogue of nonsteroidal antiexudative drugs, although there are preparations of the same action and at lower prices.
Valeriy Karimovich
I recommend to apply this cream for light bruises, small swelling, stretching during sports, in the post-traumatic period. The gel will quickly absorb into the skin, leaving no traces, quickly relieve the pain syndrome.
If there are no improvements within three days, I recommend urgently to contact a specialist for diagnosis and the appointment of a comprehensive treatment of the problem.
Alina Markovna
Satisfied patients
What people say, who tried the action of the gel on themselves.
A familiar nurse advised me to purchase this gel when I dislocated my wrist at work. Pleased and fairly affordable price, and the cooling effect of rubbing, and lack of odor, and very rapid easing of pain.
I used Febrofid for five days and my arm completely recovered. Now this miracle gel is always in my medicine cabinet.
Julia
The daughter fell off her bicycle and bruised her knee, a large hematoma and swelling formed. Having convinced on a roentgen, that the fracture is not present, the doctor has advised to buy this ointment and elastic bandages.
Already an hour after the application of the cream, the baby gently stood on his aching leg, which indicates the quality of pain relief for the bruised joint.
On the fourth day of use, the swelling passed completely, leaving a small bruise. The child completely regained activity, running without limping.
Lena
Churned up his back, caring for the beds in the country. To facilitate my condition, my wife bought this drug from the pharmacy on the advice of a pharmacist.
After the application, in just five minutes, it became much better, but, unfortunately, for a short while, after a short time the pain returned. I had to see a doctor.
Serge
After giving birth, I began to worry about my back, I am saving myself only with this remedy. A bit of gel on the lower back and after 10 minutes all as a hand removes. Does not smell, does not leave fat traces, perfectly removes pain.
Marina
Tips for using
The drug, unfortunately, has many contraindications, and therefore, it is necessary to carefully study the instructions before use in order to minimize the risks when using Febrofide.
The gel( cream) practically does not smell and does not leave traces on clothes, a small portion should be gently rubbed into a sore spot, without imposing bandages.
Do not use the drug for a long time, if no improvement occurs. Perhaps you need another remedy, which can only be properly prescribed by a doctor.
Pros and cons of the preparation
Of the positive qualities of this drug can be identified:
- rapid analgesic effect;
- is a low-fat consistency, without foreign odors, quickly absorbed;
- reasonable price.
Disadvantages:
- reduces pain for a short while;
- has a large number of contraindications;
Buying and storing
You can buy Febrophide in any pharmacy without a doctor's prescription at the following price:
- 2.5% gel with a capacity of 30 g will cost about 200-250 rubles( the price may vary depending on the region and country of the manufacturer);
- tuba 50 g costs 350-400 rubles.
Store the drug within 15-25 ° C for two years from the date of manufacture. This analgesic is on the list of OTC drugs.
Similar drugs
Non-steroidal remedies for alleviating pain syndrome similar to that of Febrofidu:
- Bystrumgel 2.5% 30 g( Russia) - 240 rubles;
- Ketonal cream 30g( Slovenia) - 280 rubles;
- Ketoprofen-gel 30 g( Russia) - 67 rubles;
- Fastum gel 2.5% 30g( Italy) - 230 rubles;
- Fleksen gel 2,5% 30g( Italy) - 150 rub.
